DK3529248T3 - Farmaceutiske sammensætninger - Google Patents

Farmaceutiske sammensætninger Download PDF

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Publication number
DK3529248T3
DK3529248T3 DK17790813.4T DK17790813T DK3529248T3 DK 3529248 T3 DK3529248 T3 DK 3529248T3 DK 17790813 T DK17790813 T DK 17790813T DK 3529248 T3 DK3529248 T3 DK 3529248T3
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DK
Denmark
Prior art keywords
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
DK17790813.4T
Other languages
Danish (da)
English (en)
Inventor
Neil Anthony Pegg
Stuart Thomas Onions
David Michel Adrien Taddei
Jonathan Shannon
Silvia Paoletta
Richard James Brown
Don Smyth
Gareth Harbottle
Original Assignee
Cellcentric Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellcentric Ltd filed Critical Cellcentric Ltd
Application granted granted Critical
Publication of DK3529248T3 publication Critical patent/DK3529248T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK17790813.4T 2016-10-18 2017-10-18 Farmaceutiske sammensætninger DK3529248T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1617630.7A GB201617630D0 (en) 2016-10-18 2016-10-18 Pharmaceutical compounds
PCT/GB2017/053152 WO2018073586A1 (en) 2016-10-18 2017-10-18 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
DK3529248T3 true DK3529248T3 (da) 2020-09-14

Family

ID=57680668

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17790813.4T DK3529248T3 (da) 2016-10-18 2017-10-18 Farmaceutiske sammensætninger

Country Status (23)

Country Link
US (2) US10696666B2 (OSRAM)
EP (1) EP3529248B1 (OSRAM)
JP (1) JP7152393B2 (OSRAM)
KR (1) KR102578786B1 (OSRAM)
CN (1) CN110049983B (OSRAM)
AU (1) AU2017346453B2 (OSRAM)
CY (1) CY1123666T1 (OSRAM)
DK (1) DK3529248T3 (OSRAM)
EA (1) EA201990643A1 (OSRAM)
ES (1) ES2828504T3 (OSRAM)
GB (1) GB201617630D0 (OSRAM)
HR (1) HRP20201444T1 (OSRAM)
HU (1) HUE052443T2 (OSRAM)
IL (1) IL266017B (OSRAM)
LT (1) LT3529248T (OSRAM)
MX (1) MX384438B (OSRAM)
PT (1) PT3529248T (OSRAM)
RS (1) RS61007B1 (OSRAM)
SG (1) SG11201903155XA (OSRAM)
SI (1) SI3529248T1 (OSRAM)
SM (1) SMT202000593T1 (OSRAM)
WO (1) WO2018073586A1 (OSRAM)
ZA (1) ZA201902334B (OSRAM)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201617630D0 (en) 2016-10-18 2016-11-30 Cellcentric Ltd Pharmaceutical compounds
GB201617627D0 (en) * 2016-10-18 2016-11-30 Cellcentric Ltd Pharmaceutical compounds
WO2019055877A1 (en) 2017-09-15 2019-03-21 Forma Therapeutics, Inc. TETRAHYDROIMIDAZO QUINOLINE COMPOSITIONS AS INHIBITORS OF CBP / P300
GB201806320D0 (en) * 2018-04-18 2018-05-30 Cellcentric Ltd Process
MX2023013508A (es) 2018-06-29 2023-12-13 Forma Therapeutics Inc Inhibicion de la proteina de union a creb (cbp).
CN113874017B (zh) * 2019-03-15 2024-11-22 福马治疗股份有限公司 抑制环amp-应答元件结合蛋白(creb)
EP3937940A4 (en) 2019-03-15 2022-12-21 Forma Therapeutics, Inc. Inhibiting cyclic amp-responsive element-binding protein (creb)
CN112574178B (zh) * 2019-09-27 2025-12-16 海创药业股份有限公司 一种氘代苯并咪唑类化合物及其作为ep300/cbp抑制剂的用途
CN112574189B (zh) * 2019-09-27 2024-05-31 海创药业股份有限公司 一种ep300/cbp抑制剂
CN112574191B (zh) * 2019-09-29 2024-01-23 南京圣和药业股份有限公司 异噁唑杂环类化合物及其应用
AU2021298154A1 (en) 2020-06-25 2023-02-23 Tolremo Therapeutics Ag Combination of a CBP/p300 bromodomain inhibitor and a KRAS inhibitor for the treatment of cancer
US20230255966A1 (en) 2020-06-25 2023-08-17 Tolremo Therapeutics Ag A combination of a cbp/p300 bromodomain inhibitor and an egfr inhibitor for use in treating egfr-mutant nsclc
US11795168B2 (en) 2020-09-23 2023-10-24 Forma Therapeutics, Inc. Inhibiting cyclic amp-responsive element-binding protein (CREB) binding protein (CBP)
US11801243B2 (en) 2020-09-23 2023-10-31 Forma Therapeutics, Inc. Bromodomain inhibitors for androgen receptor-driven cancers
TW202227429A (zh) * 2020-11-06 2022-07-16 大陸商貝達藥業股份有限公司 P300抑制劑、包含其的藥物組合物、其應用及製備其的方法
JPWO2022138944A1 (OSRAM) * 2020-12-25 2022-06-30
US20240109879A1 (en) * 2020-12-31 2024-04-04 Medshine Discovery Inc. Benzimidazole compound and application thereof
CN114989158A (zh) * 2021-03-02 2022-09-02 复旦大学 组蛋白乙酰转移酶p300溴结构域抑制剂及其药用组合物及其应用
WO2022184664A1 (en) 2021-03-02 2022-09-09 Boehringer Ingelheim International Gmbh Anticancer combination therapy
EP4257130A1 (de) * 2022-04-08 2023-10-11 Justus-Liebig-Universität Gießen Inobrodib zur behandlung von pulmonaler arterieller hypertonie

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA953311B (en) 1994-04-29 1996-10-24 Lilly Co Eli Non-peptidyl tachykinin receptor antagonists
CA2383546A1 (en) * 1999-06-30 2001-01-04 William H. Parsons Src kinase inhibitor compounds
US20030055037A1 (en) 2000-10-06 2003-03-20 Delombaert Stephane Benzimidazole and indole derivatives as CRF receptor modulators
WO2002072549A1 (en) 2001-03-12 2002-09-19 Millennium Pharmaceuticals, Inc. Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor
ATE375350T1 (de) 2002-02-21 2007-10-15 Lilly Co Eli Modulatoren von peroxisome proliferator- aktivierten rezeptoren
EP1581539A4 (en) 2003-01-03 2007-09-19 Bristol Myers Squibb Co NEW TYROSINE KINASE HEMMER
US7312215B2 (en) 2003-07-29 2007-12-25 Bristol-Myers Squibb Company Benzimidazole C-2 heterocycles as kinase inhibitors
US7687638B2 (en) 2004-06-04 2010-03-30 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
WO2006124780A2 (en) 2005-05-12 2006-11-23 Kalypsys, Inc. Ih-benzo [d] imidazole compounds as inhibitors of b-raf kinase
WO2006136823A1 (en) 2005-06-21 2006-12-28 Astex Therapeutics Limited Heterocyclic containing amines as kinase b inhibitors
AU2006311433B2 (en) * 2005-11-08 2012-06-28 Choongwae Pharma Corporation Alpha-helix mimetics and method relating to the treatment of cancer stem cells
EP1878724A1 (en) 2006-07-15 2008-01-16 sanofi-aventis A regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles
AU2007329480A1 (en) 2006-12-05 2008-06-12 National Chio Tung University Indazole compounds
ATE539063T1 (de) 2007-06-26 2012-01-15 Sanofi Sa Regioselektive, kupferkatalysierte synthese von benzimidazolen und azabenzimidazolen
WO2009023179A2 (en) 2007-08-10 2009-02-19 Genelabs Technologies, Inc. Nitrogen containing bicyclic chemical entities for treating viral infections
CA2709883A1 (en) 2007-12-19 2009-06-25 The Scripps Research Institute Benzimidazoles and analogs as rho kinase inhibitors
US8501957B2 (en) 2008-12-10 2013-08-06 China Medical University Benzimidazole compounds and their use as anticancer agents
US20110237633A1 (en) 2008-12-11 2011-09-29 Bijoy Panicker Small molecule modulators of hepatocyte growth factor (scatter factor) activity
WO2010075282A1 (en) 2008-12-22 2010-07-01 University Of Washington Molecular inhibitors of the wnt/beta-catenin pathway
ES2620177T3 (es) 2009-10-15 2017-06-27 Guerbet Agentes de formación de imágenes y su uso para el diagnóstico in vivo de enfermedades neurodegenerativas, particularmente la enfermedad de Alzheimer y enfermedades derivadas
WO2011085039A2 (en) * 2010-01-05 2011-07-14 The Johns Hopkins University Use of histone acetyltransferase inhibitors as novel anti-cancer therapies
US8455516B2 (en) 2010-01-15 2013-06-04 Touro University HIV-1 fusion inhibitors and methods
WO2011097607A1 (en) 2010-02-08 2011-08-11 Southern Research Institute Anti-viral treatment and assay to screen for anti-viral agent
MX2012013128A (es) 2010-05-13 2013-03-20 Amgen Inc Compuestos heterociclicos de nitrogeno como inhibidores de la fosfodiesterasa 10.
EP2397471A1 (en) 2010-06-16 2011-12-21 China Medical University Benzimidazole compounds and their use
JP5850503B2 (ja) 2010-09-14 2016-02-03 北海道公立大学法人 札幌医科大学 筋ジストロフィーを処置するための組成物
CA2825028A1 (en) 2011-02-09 2012-08-16 F. Hoffman-La Roche Ag Heterocyclic compounds as pi3 kinase inhibitors
ES2786298T3 (es) 2011-03-03 2020-10-09 Zalicus Pharmaceuticals Ltd Inhibidores de benzimidazol del canal de sodio
JP2014114212A (ja) 2011-03-29 2014-06-26 Dainippon Sumitomo Pharma Co Ltd 新規ベンズイミダゾール誘導体
TW201348231A (zh) 2012-02-29 2013-12-01 Amgen Inc 雜雙環化合物
EA028626B1 (ru) 2012-06-11 2017-12-29 Юсб Байофарма Спрл БЕНЗИМИДАЗОЛЫ, МОДУЛИРУЮЩИЕ TNF-α
AU2013289938A1 (en) 2012-07-13 2015-01-29 Indiana University Research & Technology Corporation Compounds for treatment of spinal muscular atrophy
JP2016000697A (ja) 2012-10-02 2016-01-07 大日本住友製薬株式会社 ピリミジン誘導体
JP2014073982A (ja) 2012-10-03 2014-04-24 Dainippon Sumitomo Pharma Co Ltd 新規ベンズイミダゾール誘導体からなる医薬
WO2014078479A2 (en) 2012-11-14 2014-05-22 The Board Of Regents Of The University Of Texas System INHIBITION OF HIF-2α HETERODIMERIZATION WITH HIF1β (ARNT)
WO2014157382A1 (ja) 2013-03-29 2014-10-02 味の素株式会社 スフィンゴシンキナーゼ阻害剤
PL231063B1 (pl) 2013-04-10 2019-01-31 Oncoarendi Therapeutics Spolka Z Ograniczona Odpowiedzialnoscia Pochodne 1-(podstawionej sulfonylo)-2-aminoimidazoliny jako środki przeciwnowotworowe
TWI527811B (zh) 2013-05-09 2016-04-01 吉李德科學股份有限公司 作爲溴結構域抑制劑的苯並咪唑衍生物
EP3010918B1 (en) * 2013-06-21 2018-08-15 Zenith Epigenetics Ltd. Novel substituted bicyclic compounds as bromodomain inhibitors
US10471139B2 (en) 2013-08-15 2019-11-12 The University Of Kansas Toll-like receptor agonists
GB201321741D0 (en) 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents
JP6785217B2 (ja) 2014-07-31 2020-11-18 インスティチュート パスツール コリア 2−アミノ−ベンゾイミダゾール誘導体ならびにこれらの5−リポキシゲナーゼおよび/またはプロスタグランジンeシンターゼ阻害剤としての使用
US9763922B2 (en) * 2014-11-27 2017-09-19 Genentech, Inc. Therapeutic compounds and uses thereof
GB201506660D0 (en) * 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
GB201506658D0 (en) * 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
WO2016200401A1 (en) 2015-06-12 2016-12-15 Transitions Optical, Inc. Alignment compounds
CN108137539B (zh) 2015-08-12 2022-01-11 尼奥迈德研究所 取代的苯并咪唑、它们的制备和它们作为药物的用途
AU2016329075A1 (en) 2015-10-02 2018-04-26 Gilead Sciences, Inc. Combinations of the BTK inhibitor GS-4059 with inhibitors selected from a JAK, ASK1, BRD and/or MMP9 inhibitor to treat cancer, allergic disorders, autoimmune diseases or inflammatory diseases
WO2017100525A1 (en) 2015-12-11 2017-06-15 The Board Of Regents Of The University Of Texas System Substituted benzimidazolium, pyrido-imidazolium, or pyrazino-imidazolium compounds as chemotherapeutics
WO2017106568A1 (en) 2015-12-17 2017-06-22 Gilead Sciences, Inc. Combination of a jak inhibitor and a bromodomain inhibitor for treating cancer
CN109641838A (zh) 2016-06-21 2019-04-16 X4 制药有限公司 Cxcr4抑制剂及其用途
WO2017223229A1 (en) 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
GB201617630D0 (en) 2016-10-18 2016-11-30 Cellcentric Ltd Pharmaceutical compounds
GB201617627D0 (en) * 2016-10-18 2016-11-30 Cellcentric Ltd Pharmaceutical compounds
WO2018097976A1 (en) 2016-11-22 2018-05-31 Gilead Sciences, Inc. Synthesis of a compound that modulates the activity of bromodomain-containing proteins

Also Published As

Publication number Publication date
US10696666B2 (en) 2020-06-30
JP2019537571A (ja) 2019-12-26
KR102578786B1 (ko) 2023-09-15
ZA201902334B (en) 2022-10-26
KR20190075095A (ko) 2019-06-28
CN110049983A (zh) 2019-07-23
EP3529248A1 (en) 2019-08-28
NZ752354A (en) 2025-02-28
AU2017346453B2 (en) 2022-02-17
BR112019007834A2 (pt) 2019-07-16
HRP20201444T1 (hr) 2020-12-11
AU2017346453A1 (en) 2019-05-02
US20200407349A1 (en) 2020-12-31
JP7152393B2 (ja) 2022-10-12
CA3039641A1 (en) 2018-04-26
SI3529248T1 (sl) 2020-11-30
RS61007B1 (sr) 2020-11-30
US20190375740A1 (en) 2019-12-12
IL266017A (en) 2019-06-30
HUE052443T2 (hu) 2021-04-28
ES2828504T3 (es) 2021-05-26
GB201617630D0 (en) 2016-11-30
EP3529248B1 (en) 2020-08-19
MX2019004113A (es) 2019-09-09
SG11201903155XA (en) 2019-05-30
US11377443B2 (en) 2022-07-05
IL266017B (en) 2021-08-31
SMT202000593T1 (it) 2020-11-10
MX384438B (es) 2025-03-14
CN110049983B (zh) 2022-06-14
EA201990643A1 (ru) 2019-11-29
CY1123666T1 (el) 2022-03-24
LT3529248T (lt) 2020-10-26
WO2018073586A1 (en) 2018-04-26
PT3529248T (pt) 2020-09-03

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