MX384232B - Vesiculas colestosomicas para incorporacion de moleculas en quilomicrones. - Google Patents
Vesiculas colestosomicas para incorporacion de moleculas en quilomicrones.Info
- Publication number
- MX384232B MX384232B MX2015011462A MX2015011462A MX384232B MX 384232 B MX384232 B MX 384232B MX 2015011462 A MX2015011462 A MX 2015011462A MX 2015011462 A MX2015011462 A MX 2015011462A MX 384232 B MX384232 B MX 384232B
- Authority
- MX
- Mexico
- Prior art keywords
- cholestosome
- loaded
- present
- patient
- molecules
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1275—Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Communicable Diseases (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361783003P | 2013-03-14 | 2013-03-14 | |
| PCT/US2014/027761 WO2014152795A2 (en) | 2013-03-14 | 2014-03-14 | Cholestosome vesicles for incorporation of molecules into chylomicrons |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015011462A MX2015011462A (es) | 2016-05-31 |
| MX384232B true MX384232B (es) | 2025-03-14 |
Family
ID=51581747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015011462A MX384232B (es) | 2013-03-14 | 2014-03-14 | Vesiculas colestosomicas para incorporacion de moleculas en quilomicrones. |
Country Status (10)
| Country | Link |
|---|---|
| US (6) | US9693968B2 (https=) |
| EP (1) | EP2970369B1 (https=) |
| JP (2) | JP2016513712A (https=) |
| CN (1) | CN105164143B (https=) |
| AU (1) | AU2014236559B2 (https=) |
| BR (1) | BR112015022936A2 (https=) |
| CA (1) | CA2905108C (https=) |
| IL (1) | IL241501B (https=) |
| MX (1) | MX384232B (https=) |
| WO (1) | WO2014152795A2 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9119782B2 (en) | 2006-03-20 | 2015-09-01 | Mary P. McCourt | Drug delivery means |
| US20180099001A1 (en) | 2011-04-29 | 2018-04-12 | Volant Holdings Gmbh | Diagnostics and methods for treatment of non-alcoholic hepatic steatosis and hepatic steatohepatitis, and prevention of complications thereof |
| MX384232B (es) | 2013-03-14 | 2025-03-14 | Jerome J Schentag | Vesiculas colestosomicas para incorporacion de moleculas en quilomicrones. |
| CN105579582A (zh) | 2013-07-25 | 2016-05-11 | 埃克西奎雷股份有限公司 | 用于预防和治疗用途的作为免疫刺激剂的基于球形核酸的构建体 |
| WO2016054399A1 (en) * | 2014-10-01 | 2016-04-07 | The Brigham And Women's Hospital, Inc. | Enhancing dermal wound healing by downregulating microrna-26a |
| ES2574615B1 (es) * | 2014-12-19 | 2017-07-24 | Biopraxis Research Aie | Nanopartícula lipídica de tobramicina |
| CN108697768B (zh) | 2015-12-23 | 2022-07-22 | 约翰霍普金斯大学 | 长效glp-1r激动剂作为神经系统病状和神经退行性病状的治疗方法 |
| CN105797132A (zh) * | 2016-05-03 | 2016-07-27 | 滨州医学院 | 沙奎拉韦的医药新用途 |
| CN110418636A (zh) * | 2016-08-23 | 2019-11-05 | 杰罗米.J.申塔格 | 将肽、蛋白质和核酸负载至乳糜微粒和体细胞中的胆固醇酯囊泡 |
| US11364304B2 (en) | 2016-08-25 | 2022-06-21 | Northwestern University | Crosslinked micellar spherical nucleic acids |
| CN107260681A (zh) * | 2017-08-04 | 2017-10-20 | 济南维瑞医药科技开发有限公司 | 一种磷酸特地唑胺脂质体的制备方法及其应用 |
| WO2019032877A1 (en) * | 2017-08-09 | 2019-02-14 | Arizona Board Of Regents On Behalf Of The University Of Arizona | MICELLES AND VESICLES FOR RELEASE OF GLYCOPEPTIDES |
| US12478585B2 (en) | 2017-08-09 | 2025-11-25 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Micelles and vesicles for the delivery of glycopeptides |
| US12078642B2 (en) * | 2017-11-09 | 2024-09-03 | The University Of Melbourne | Methods for evaluating and improving cognitive function |
| CN109929806B (zh) * | 2017-12-19 | 2020-05-08 | 北京吉源生物科技有限公司 | 一种表达glp1和fgf21的干细胞及其用途 |
| JP2021512051A (ja) | 2018-01-23 | 2021-05-13 | ギラ セラピューティクス インコーポレイテッドGila Therapeutics, Inc. | ペプチドyy薬学的調剤物、組成物、および方法 |
| CA3128398A1 (en) | 2018-02-01 | 2019-08-08 | The Royal Institution For The Advancement Of Learning / Mcgill University | Formulations for improving the delivery of hydrophobic agents |
| US12064406B2 (en) | 2019-05-14 | 2024-08-20 | Pharmosa Biopharm Inc. | Pharmaceutical composition of a weak acid drug and methods of administration |
| IL322315A (en) | 2019-05-14 | 2025-09-01 | Provention Bio Inc | Methods and preparations for preventing type 1 diabetes |
| CN110638788A (zh) * | 2019-10-25 | 2020-01-03 | 广州医科大学 | 一种能够沉默Pcsk9蛋白的siRNA、其纳米递送系统及应用 |
| AU2021287998B2 (en) | 2020-06-11 | 2026-03-12 | Benaroya Research Institute At Virginia Mason | Methods and compositions for preventing type 1 diabetes |
| WO2022067336A1 (en) * | 2020-09-25 | 2022-03-31 | Algorithm Sciences, Inc. | Compositions and methods for vasodilator delivery |
| US12565529B2 (en) | 2021-05-24 | 2026-03-03 | Provention Bio, Inc. | Methods for treating type 1 diabetes |
| JP7505831B2 (ja) * | 2021-12-14 | 2024-06-25 | シード医療製薬株式会社 | 海藻抽出物を含む高血圧症改善剤並びに同高血圧症改善剤を含む機能性食品、医薬部外品及び医薬品 |
| CN114470186B (zh) * | 2022-02-17 | 2023-10-20 | 唐颐控股(深圳)有限公司 | 一种可吸入式纳米新冠疫苗的制备方法 |
| AU2023238223A1 (en) | 2022-03-23 | 2024-10-10 | Nanovation Therapeutics Inc. | High sterol-containing lipid nanoparticles |
| CN119837820B (zh) * | 2023-12-13 | 2025-10-10 | 上海交通大学 | 一种基于蛋白载体的活性成分透皮递送系统及其制备方法和应用 |
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| US20110268653A1 (en) | 2010-04-16 | 2011-11-03 | The Board Of Regents Of The University Of Texas System | Compositions and Methods Related to Acid Stable Lipid Nanospheres |
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| KR20190060879A (ko) | 2011-03-02 | 2019-06-03 | 제롬 쉔타그 | 단독으로 또는 c형 간염 바이러스 감염과 결합되는 간 지방증의 치료를 위한 조성물, 방법 및 진단 |
| US20140199233A1 (en) * | 2011-05-11 | 2014-07-17 | The Regents Of The University Of California | Enhanced Growth Inhibition of Osteosarcoma by Cytotoxic Polymerized Liposomal Nanoparticles Targeting the Alcam Cell Surface Receptor |
| US9693969B2 (en) | 2012-01-02 | 2017-07-04 | Andrew L. SKIGEN | Mucous membrane active agent application |
| JP6203816B2 (ja) | 2012-03-29 | 2017-09-27 | セラバイオーム,エルエルシー | 回腸及び虫垂に対して活性の胃腸部位特異的経口ワクチン接種製剤 |
| MX384232B (es) * | 2013-03-14 | 2025-03-14 | Jerome J Schentag | Vesiculas colestosomicas para incorporacion de moleculas en quilomicrones. |
| US9833486B2 (en) | 2013-03-15 | 2017-12-05 | Alltech, Inc. | Compositions comprising selenium and use of same for the treatment and prevention of disease or conditions associated with mitochondrial dysfunction |
| WO2016155809A1 (en) | 2015-03-31 | 2016-10-06 | Biontech Rna Pharmaceuticals Gmbh | Lipid particle formulations for delivery of rna and water-soluble therapeutically effective compounds to a target cell |
| CN110418636A (zh) | 2016-08-23 | 2019-11-05 | 杰罗米.J.申塔格 | 将肽、蛋白质和核酸负载至乳糜微粒和体细胞中的胆固醇酯囊泡 |
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| HK1212354A1 (en) | 2016-06-10 |
| US20230277471A1 (en) | 2023-09-07 |
| US10369114B2 (en) | 2019-08-06 |
| IL241501B (en) | 2020-05-31 |
| US20200069598A1 (en) | 2020-03-05 |
| EP2970369A2 (en) | 2016-01-20 |
| US20220040116A1 (en) | 2022-02-10 |
| EP2970369A4 (en) | 2016-10-12 |
| CA2905108C (en) | 2021-12-07 |
| JP2019070031A (ja) | 2019-05-09 |
| WO2014152795A2 (en) | 2014-09-25 |
| CN105164143A (zh) | 2015-12-16 |
| MX2015011462A (es) | 2016-05-31 |
| US9693968B2 (en) | 2017-07-04 |
| US20240398719A1 (en) | 2024-12-05 |
| CN105164143B (zh) | 2019-02-19 |
| US12005146B2 (en) | 2024-06-11 |
| IL241501A0 (en) | 2015-11-30 |
| JP2016513712A (ja) | 2016-05-16 |
| JP6688408B2 (ja) | 2020-04-28 |
| US11633364B2 (en) | 2023-04-25 |
| US11052052B2 (en) | 2021-07-06 |
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| WO2014152795A3 (en) | 2014-11-27 |
| EP2970369B1 (en) | 2023-11-22 |
| AU2014236559A1 (en) | 2018-05-24 |
| US20160030361A1 (en) | 2016-02-04 |
| US12465575B2 (en) | 2025-11-11 |
| US20180055780A1 (en) | 2018-03-01 |
| BR112015022936A2 (pt) | 2017-07-18 |
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