BR112014010811A2 - redes de gotículas encapsuladas multisomas - Google Patents
redes de gotículas encapsuladas multisomasInfo
- Publication number
- BR112014010811A2 BR112014010811A2 BR112014010811A BR112014010811A BR112014010811A2 BR 112014010811 A2 BR112014010811 A2 BR 112014010811A2 BR 112014010811 A BR112014010811 A BR 112014010811A BR 112014010811 A BR112014010811 A BR 112014010811A BR 112014010811 A2 BR112014010811 A2 BR 112014010811A2
- Authority
- BR
- Brazil
- Prior art keywords
- encapsulated
- droplet
- multisome
- encapsulated droplet
- drop
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/025—Applications of microcapsules not provided for in other subclasses
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
- C09B67/0097—Dye preparations of special physical nature; Tablets, films, extrusion, microcapsules, sheets, pads, bags with dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
resumo redes de gotículas encapsuladas multisomas a invenção proporciona uma gotícula encapsulada compreendendo: uma gota de um meio hidrofóbico; uma camada periférica de moléculas anfipáticas não poliméricas em torno da superfície da gota; e uma gotícula de solução aquosa no interior da camada periférica, a gotícula solução aquosa compreendendo: (a) um meio aquoso, e (b) uma camada externa de moléculas anfipáticas não poliméricas em torno da superfície do meio aquoso. a invenção também proporciona processos para preparar as gotículas encapsuladas. várias utilizações da gotícula encapsulada são também descritas, incluindo a sua utilização como veículos de entrega de drogas, em biologia sintética, e no estudo de proteínas de membrana.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1119032.9A GB201119032D0 (en) | 2011-11-03 | 2011-11-03 | Multisomes: encapsulated droplet networks |
GB1119032.9 | 2011-11-03 | ||
US201261592062P | 2012-01-30 | 2012-01-30 | |
US61/592,062 | 2012-01-30 | ||
PCT/GB2012/052736 WO2013064837A1 (en) | 2011-11-03 | 2012-11-02 | Multisomes: encapsulated droplet networks |
Publications (3)
Publication Number | Publication Date |
---|---|
BR112014010811A2 true BR112014010811A2 (pt) | 2017-05-02 |
BR112014010811A8 BR112014010811A8 (pt) | 2018-01-02 |
BR112014010811B1 BR112014010811B1 (pt) | 2022-07-12 |
Family
ID=45375781
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014010811-0A BR112014010811B1 (pt) | 2011-11-03 | 2012-11-02 | Multissomas: redes de gotículas encapsuladas |
Country Status (11)
Country | Link |
---|---|
US (3) | US10548852B2 (pt) |
EP (1) | EP2773451A1 (pt) |
JP (1) | JP6234371B2 (pt) |
KR (1) | KR102038450B1 (pt) |
CN (1) | CN104053497B (pt) |
AU (1) | AU2012330894B2 (pt) |
BR (1) | BR112014010811B1 (pt) |
CA (1) | CA2853966C (pt) |
GB (1) | GB201119032D0 (pt) |
IN (1) | IN2014CN03680A (pt) |
WO (1) | WO2013064837A1 (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201119032D0 (en) | 2011-11-03 | 2011-12-14 | Isis Innovation | Multisomes: encapsulated droplet networks |
GB201219201D0 (en) | 2012-10-25 | 2012-12-12 | Isis Innovation | Hydrogel network |
GB201219196D0 (en) | 2012-10-25 | 2012-12-12 | Isis Innovation | Droplet assembly method |
EP2928610A2 (en) | 2012-12-07 | 2015-10-14 | Isis Innovation Limited | Droplet assembly by 3d printing |
WO2014093714A1 (en) * | 2012-12-14 | 2014-06-19 | Bio-Rad Laboratories, Inc. | Methods and compositions for using oils for analysis and detection of molecules |
FR3000688B1 (fr) * | 2013-01-08 | 2016-09-30 | Centre Nat De La Rech Scient - Cnrs - | Procede pour activer une reaction chimique, melange activable par ce procede et dispostiif pour la mise en oeuvre de ce procede |
US9758535B2 (en) | 2013-03-15 | 2017-09-12 | Bio-Rad Laboratories, Inc. | Silicone surfactants for emulsion assays |
MX2016002560A (es) * | 2013-08-29 | 2016-10-26 | Teva Pharma | Forma de dosificacion unitaria que comprende emtricitabina, tenofovir, darunavir y ritonavir y un comprimido monolitico que comprende darunavir y ritonavir. |
WO2015155673A1 (en) * | 2014-04-08 | 2015-10-15 | Teva Pharmaceutical Industries Ltd | Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir |
WO2016057829A1 (en) | 2014-10-10 | 2016-04-14 | Quantapore, Inc. | Nanopore-based polymer analysis with mutually-quenching fluorescent labels |
WO2017004504A1 (en) | 2015-07-02 | 2017-01-05 | The University Of Massachusetts | Membrane and droplet-interface bilayer systems and methods |
US20190078145A1 (en) | 2015-12-08 | 2019-03-14 | Quantapore, Inc. | Method of translocating nucleic acids through nanopores |
AU2017225355A1 (en) | 2016-03-01 | 2018-09-13 | Oxford University Innovation Limited | Phase transfer of a cargo laden scaffold |
GB201603591D0 (en) * | 2016-03-01 | 2016-04-13 | Isis Innovation | Improved promotors and compositions |
GB201615741D0 (en) * | 2016-09-15 | 2016-11-02 | Univ College Cardiff Consultants Ltd | Artificial cells |
GB2561157A (en) * | 2017-03-27 | 2018-10-10 | Univ Oxford Innovation Ltd | Compartmentalised gel matrix and method of production |
CN110961055B (zh) * | 2019-12-06 | 2021-01-05 | 锦州医科大学 | 离子液体聚合微球及其制备方法和应用 |
WO2021192861A1 (ja) * | 2020-03-26 | 2021-09-30 | 国立大学法人九州大学 | イオン液体、溶媒、製剤および経皮吸収剤 |
CN112588218B (zh) * | 2020-12-11 | 2021-09-21 | 中国科学院力学研究所 | 一种实现液滴快速自发旋转的方法 |
CN114250190A (zh) * | 2021-12-22 | 2022-03-29 | 北京京东方技术开发有限公司 | 封装细胞及其制备方法 |
Family Cites Families (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4812856A (en) | 1987-10-30 | 1989-03-14 | Microfab Technologies, Inc. | Method and apparatus for dispensing a fluid with dispersed particles therein |
US5104736A (en) | 1988-03-03 | 1992-04-14 | Micro-Pak, Inc. | Reinforced paucilamellar lipid vesicles |
US4934564A (en) | 1989-03-23 | 1990-06-19 | Eastman Kodak Company | Drop jet metering method and system |
US5858399A (en) * | 1992-04-09 | 1999-01-12 | Northwestern University | Acoustically reflective liposomes and methods to make and use the same |
US5464629A (en) | 1993-11-16 | 1995-11-07 | Georgetown University | Method of forming hydrogel particles having a controlled size using liposomes |
US6531156B1 (en) | 1994-04-15 | 2003-03-11 | Temple University | Aqueous solven encapsulation method, apparatus and microcapsules |
DE4438232A1 (de) | 1994-10-26 | 1996-05-02 | Guenter Prof Dr Fuhr | Kryokonservierung und Tieftemperaturbearbeitung von biologischen Zellen |
US5891467A (en) | 1997-01-31 | 1999-04-06 | Depotech Corporation | Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes |
CA2564120C (en) | 1997-01-31 | 2010-04-13 | Skyepharma Inc. | Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes |
US6106858A (en) * | 1997-09-08 | 2000-08-22 | Skyepharma, Inc. | Modulation of drug loading in multivescular liposomes |
US7470547B2 (en) | 2003-07-31 | 2008-12-30 | Biodot, Inc. | Methods and systems for dispensing sub-microfluidic drops |
US6461812B2 (en) | 1998-09-09 | 2002-10-08 | Agilent Technologies, Inc. | Method and multiple reservoir apparatus for fabrication of biomolecular arrays |
ES2230901T3 (es) * | 1998-12-05 | 2005-05-01 | Imperial Chemical Industries Plc | Sistema emulsionantes y emulsiones. |
EP1099484B1 (en) | 1999-11-11 | 2006-06-07 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | A dispensing method and assembly for liquid droplets |
US20030048341A1 (en) | 2000-09-25 | 2003-03-13 | Mutz Mitchell W. | High-throughput biomolecular crystallization and biomolecular crystal screening |
US20020106308A1 (en) | 2001-02-02 | 2002-08-08 | Zweifel Ronald A. | Microdrop dispensing apparatus |
US20030119193A1 (en) | 2001-04-25 | 2003-06-26 | Robert Hess | System and method for high throughput screening of droplets |
US7943067B2 (en) | 2001-08-16 | 2011-05-17 | Polytechnic Institute Of New York University | Nanogels and their production using liposomes as reactors |
US6995024B2 (en) | 2001-08-27 | 2006-02-07 | Sri International | Method and apparatus for electrostatic dispensing of microdroplets |
US6962747B1 (en) | 2001-10-23 | 2005-11-08 | Sandia Corporation | Self-assembled lipid bilayer materials |
US6945638B2 (en) | 2001-10-29 | 2005-09-20 | Therics, Inc. | Method and system for controlling the temperature of a dispensed liquid |
US6960298B2 (en) | 2001-12-10 | 2005-11-01 | Nanogen, Inc. | Mesoporous permeation layers for use on active electronic matrix devices |
FR2846041B1 (fr) * | 2002-10-18 | 2006-06-09 | Peugeot Citroen Automobiles Sa | Moteur a combustion interne a suralimentation et bougie a prechambre, procede d'allumage et application |
US7160614B2 (en) | 2002-11-01 | 2007-01-09 | Sony Corporation | Crystalline superfine particles, complex material, method of manufacturing crystalline superfine particles, inverted micelles, inverted micelles enveloping precursor superfine particles, inverted micelles enveloping crystalline superfine particles, and precursor superfine particles |
KR20110097971A (ko) * | 2003-04-25 | 2011-08-31 | 메디뮨 백신즈, 인코포레이티드 | 메타뉴모바이러스 유래 이종 항원을 포함하는 재조합 파라인플루엔자 바이러스 발현 시스템 및 백신 |
US7914714B2 (en) | 2003-05-14 | 2011-03-29 | The Regents Of The University Of Colorado | Methods and apparatus using electrostatic atomization to form liquid vesicles |
US7051654B2 (en) | 2003-05-30 | 2006-05-30 | Clemson University | Ink-jet printing of viable cells |
US7217410B2 (en) | 2003-06-17 | 2007-05-15 | The Board Of Trustees Of The Universtiy Of Illinois | Surface modified protein microparticles |
JPWO2005053643A1 (ja) | 2003-12-01 | 2007-06-28 | 三菱ウェルファーマ株式会社 | リポソーム |
AU2004303805A1 (en) * | 2003-12-16 | 2005-07-07 | Aventis Pharmaceuticals Inc | Secreted neural apoptosis inhibiting proteins |
US20080226500A1 (en) | 2004-01-15 | 2008-09-18 | Mitsuhiro Shikida | Chemical Analytic Apparatus and Chemical Analytic Method |
JP2008535644A (ja) * | 2005-03-04 | 2008-09-04 | プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ | 多重エマルジョンの形成のための方法および装置 |
US20060210443A1 (en) | 2005-03-14 | 2006-09-21 | Stearns Richard G | Avoidance of bouncing and splashing in droplet-based fluid transport |
GB0505971D0 (en) | 2005-03-23 | 2005-04-27 | Isis Innovation | Delivery of molecules to a lipid bilayer |
EP1874950B1 (en) * | 2005-04-05 | 2015-06-03 | Corning Incorporated | Label free biosensors |
JP2007046595A (ja) | 2005-07-15 | 2007-02-22 | Daikin Ind Ltd | 回転式圧縮機 |
JP5114702B2 (ja) | 2005-07-29 | 2013-01-09 | 国立大学法人 東京大学 | 両親媒性単分子膜の接触による二分子膜の形成方法およびその装置 |
US20070148697A1 (en) | 2005-12-27 | 2007-06-28 | Boston Scientific Scimed, Inc. | Methods and system for high throughput screening of polymer materials for medical devices |
US8216855B2 (en) | 2006-02-13 | 2012-07-10 | Agency For Science, Technology And Research | Method of processing a biological and/or chemical sample |
WO2007101174A2 (en) | 2006-02-27 | 2007-09-07 | Arizona Board Of Regents For And On Behalf Of Arizona State University | Digital magnetofluidic devices and methods |
US8492168B2 (en) | 2006-04-18 | 2013-07-23 | Advanced Liquid Logic Inc. | Droplet-based affinity assays |
US7439014B2 (en) | 2006-04-18 | 2008-10-21 | Advanced Liquid Logic, Inc. | Droplet-based surface modification and washing |
US7901947B2 (en) | 2006-04-18 | 2011-03-08 | Advanced Liquid Logic, Inc. | Droplet-based particle sorting |
US20090208466A1 (en) | 2006-04-21 | 2009-08-20 | James Yoo | Ink-jet printing of tissues |
US20070293449A1 (en) * | 2006-06-20 | 2007-12-20 | Nastech Pharmaceutical Company Inc. | Compositions and methods for delivery of double-stranded rna |
KR100817086B1 (ko) | 2006-07-21 | 2008-03-26 | 삼성전자주식회사 | 비전도성 모세관 노즐을 구비한 전하집중 방식 액적디스펜싱 장치 |
GB0614835D0 (en) * | 2006-07-26 | 2006-09-06 | Isis Innovation | Formation of bilayers of amphipathic molecules |
JP2010503417A (ja) | 2006-09-19 | 2010-02-04 | ホリズン サイエンス ピーティーワイ リミテッド | サトウキビに由来する抽出物、およびこれらの製造方法 |
EP1920765A1 (en) | 2006-11-07 | 2008-05-14 | Medigene AG | Liposome preparation by single-pass process |
US7776927B2 (en) | 2007-03-28 | 2010-08-17 | President And Fellows Of Harvard College | Emulsions and techniques for formation |
GB0716264D0 (en) | 2007-08-21 | 2007-09-26 | Isis Innovation | Bilayers |
US8293339B2 (en) | 2007-09-17 | 2012-10-23 | Sri International, Inc. | Droplet bilayers |
US9468607B2 (en) | 2007-10-09 | 2016-10-18 | Washington University | Ligand directed toroidal nanoparticles for therapy and diagnostic imaging |
EP2232535A4 (en) | 2007-12-10 | 2016-04-13 | Advanced Liquid Logic Inc | DROPLET ACTUATOR CONFIGURATIONS AND METHODS |
WO2009111723A1 (en) | 2008-03-07 | 2009-09-11 | Drexel University | Electrowetting microarray printing system and methods for bioactive tissue construct manufacturing |
US8270148B2 (en) | 2008-03-14 | 2012-09-18 | David Griffith | Suspension for a pressure sensitive touch display or panel |
WO2009148598A1 (en) * | 2008-06-05 | 2009-12-10 | President And Fellows Of Harvard College | Polymersomes, colloidosomes, liposomes, and other species associated with fluidic droplets |
US9156010B2 (en) | 2008-09-23 | 2015-10-13 | Bio-Rad Laboratories, Inc. | Droplet-based assay system |
GB0909154D0 (en) | 2008-09-25 | 2009-07-08 | Nanomaterials Tech Pte Ltd | A process for making particles for delivery of drug nanoparticles |
US20110250688A1 (en) | 2008-11-24 | 2011-10-13 | Immunotrex Corporation | Three Dimensional Tissue Generation |
JP5487666B2 (ja) * | 2009-03-23 | 2014-05-07 | コニカミノルタ株式会社 | 内水相を固定化することを特徴とするリポソームの製造方法 |
WO2010110471A1 (ja) * | 2009-03-23 | 2010-09-30 | 国立大学法人北海道大学 | 脂質膜構造体 |
EP2599548B1 (de) | 2009-05-13 | 2018-07-04 | ibidi GmbH | Probenträger zum Positionieren einer organischen, biologischen und/oder medizinischen Probe |
GB0913823D0 (en) | 2009-08-07 | 2009-09-16 | Isis Innovation | Bilayers |
US8992984B1 (en) * | 2009-10-21 | 2015-03-31 | Stc.Unm | Protocells and their use for targeted delivery of multicomponent cargos to cancer cells |
WO2011107599A1 (en) | 2010-03-04 | 2011-09-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Bioprinting station, assembly comprising such bioprinting station and bioprinting method |
US20110312744A1 (en) | 2010-06-17 | 2011-12-22 | Geneasys Pty Ltd | Microfluidic device for amplifying mitochondrial dna in a biological sample |
US20120006681A1 (en) | 2010-07-06 | 2012-01-12 | Kaler Karan V I S | Controlled Dispensing of Ultrafine, Variable Volume, Emulsion Droplets |
KR101550941B1 (ko) | 2010-10-14 | 2015-09-07 | (주)아모레퍼시픽 | 리피드가 코팅된 하이드로겔 입자 및 이의 제조방법 |
US9849089B2 (en) | 2010-10-14 | 2017-12-26 | Amorepacific Corporation | Hydrogel particle coated with lipid and method for manufacturing same |
US9149952B2 (en) | 2010-10-21 | 2015-10-06 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue |
JP2012166159A (ja) | 2011-02-15 | 2012-09-06 | Microjet:Kk | 吐出装置および吐出する方法 |
US8944083B2 (en) | 2011-06-15 | 2015-02-03 | Ut-Battelle, Llc | Generation of monodisperse droplets by shape-induced shear and interfacial controlled fusion of individual droplets on-demand |
CN103930210B (zh) | 2011-09-19 | 2018-06-12 | 国家科学研究中心 | 微流体系统 |
GB201119032D0 (en) | 2011-11-03 | 2011-12-14 | Isis Innovation | Multisomes: encapsulated droplet networks |
US20130319861A1 (en) | 2012-05-30 | 2013-12-05 | Berkeley Lights, Inc. | Outputting A Droplet Of Liquid Medium From A Device For Processing Micro-Objects In The Medium |
US9223317B2 (en) | 2012-06-14 | 2015-12-29 | Advanced Liquid Logic, Inc. | Droplet actuators that include molecular barrier coatings |
US20140023697A1 (en) | 2012-07-17 | 2014-01-23 | Iona College | Methods and systems for nanomembrane crystallization |
GB201219196D0 (en) | 2012-10-25 | 2012-12-12 | Isis Innovation | Droplet assembly method |
GB201219201D0 (en) | 2012-10-25 | 2012-12-12 | Isis Innovation | Hydrogel network |
WO2014064444A1 (en) | 2012-10-26 | 2014-05-01 | Oxford Nanopore Technologies Limited | Droplet interfaces |
EP2928610A2 (en) | 2012-12-07 | 2015-10-14 | Isis Innovation Limited | Droplet assembly by 3d printing |
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2011
- 2011-11-03 GB GBGB1119032.9A patent/GB201119032D0/en not_active Ceased
-
2012
- 2012-11-02 AU AU2012330894A patent/AU2012330894B2/en active Active
- 2012-11-02 BR BR112014010811-0A patent/BR112014010811B1/pt active IP Right Grant
- 2012-11-02 US US14/354,706 patent/US10548852B2/en active Active
- 2012-11-02 IN IN3680CHN2014 patent/IN2014CN03680A/en unknown
- 2012-11-02 CN CN201280065007.0A patent/CN104053497B/zh active Active
- 2012-11-02 CA CA2853966A patent/CA2853966C/en active Active
- 2012-11-02 WO PCT/GB2012/052736 patent/WO2013064837A1/en active Application Filing
- 2012-11-02 JP JP2014539406A patent/JP6234371B2/ja active Active
- 2012-11-02 KR KR1020147015197A patent/KR102038450B1/ko active IP Right Grant
- 2012-11-02 EP EP12784659.0A patent/EP2773451A1/en active Pending
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2019
- 2019-12-19 US US16/721,302 patent/US11406603B2/en active Active
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2022
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Also Published As
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CA2853966C (en) | 2021-07-06 |
JP2015501328A (ja) | 2015-01-15 |
US11406603B2 (en) | 2022-08-09 |
BR112014010811B1 (pt) | 2022-07-12 |
AU2012330894A1 (en) | 2014-05-29 |
US11998642B2 (en) | 2024-06-04 |
EP2773451A1 (en) | 2014-09-10 |
KR20140097303A (ko) | 2014-08-06 |
US20200214988A1 (en) | 2020-07-09 |
US20230048266A1 (en) | 2023-02-16 |
GB201119032D0 (en) | 2011-12-14 |
JP6234371B2 (ja) | 2017-11-22 |
WO2013064837A1 (en) | 2013-05-10 |
CN104053497A (zh) | 2014-09-17 |
KR102038450B1 (ko) | 2019-11-26 |
AU2012330894B2 (en) | 2017-07-13 |
BR112014010811A8 (pt) | 2018-01-02 |
IN2014CN03680A (pt) | 2015-09-25 |
CN104053497B (zh) | 2017-04-26 |
CA2853966A1 (en) | 2013-05-10 |
US20140356289A1 (en) | 2014-12-04 |
US10548852B2 (en) | 2020-02-04 |
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