MX2014014590A - Microcapsulas que contienen retinoides, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Microcapsulas que contienen retinoides, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
MX2014014590A
MX2014014590A MX2014014590A MX2014014590A MX2014014590A MX 2014014590 A MX2014014590 A MX 2014014590A MX 2014014590 A MX2014014590 A MX 2014014590A MX 2014014590 A MX2014014590 A MX 2014014590A MX 2014014590 A MX2014014590 A MX 2014014590A
Authority
MX
Mexico
Prior art keywords
same
microcapsules
pharmaceutical compositions
retinoids
preparing
Prior art date
Application number
MX2014014590A
Other languages
English (en)
Inventor
Amel Djedour
Original Assignee
Galderma Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Res & Dev filed Critical Galderma Res & Dev
Publication of MX2014014590A publication Critical patent/MX2014014590A/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

La presente invención se refiere a microcápsulas que incluyen un agente farmacéutico activo seleccionado a partir de retinoides, un polímero hidrofílico aniónico (en particular goma arábica), y un polímero hidrofílico catiónico (en particular, gelatina tipo-A). La presente invención también se refiere a métodos para preparar tales microcápsulas, a composiciones farmacéuticas tópicas que incluyen tales microcápsulas, y al uso dermatológico de las mismas.
MX2014014590A 2012-06-01 2013-05-30 Microcapsulas que contienen retinoides, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. MX2014014590A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261654723P 2012-06-01 2012-06-01
FR1255108A FR2991172A1 (fr) 2012-06-01 2012-06-01 Compositions pharmaceutiques topiques comprenant des microcapsules
PCT/EP2013/061183 WO2013178743A1 (fr) 2012-06-01 2013-05-30 Microcapsules contenant des rétinoïdes, leur procédé de préparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
MX2014014590A true MX2014014590A (es) 2015-03-03

Family

ID=46889199

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014014590A MX2014014590A (es) 2012-06-01 2013-05-30 Microcapsulas que contienen retinoides, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.

Country Status (12)

Country Link
US (1) US20150190372A1 (es)
EP (1) EP2854775A1 (es)
JP (1) JP2015518031A (es)
KR (1) KR20150014522A (es)
CN (1) CN104661656A (es)
AU (1) AU2013269566A1 (es)
BR (1) BR112014029869A2 (es)
CA (1) CA2874375A1 (es)
FR (1) FR2991172A1 (es)
MX (1) MX2014014590A (es)
RU (1) RU2014152994A (es)
WO (1) WO2013178743A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3099290A1 (en) * 2014-01-28 2016-12-07 Allergan, Inc. Topical retinoid formulations and methods of use
KR102406880B1 (ko) 2015-10-30 2022-06-08 팀버 파마슈티칼스 엘엘씨 이소트레티노인 제형 및 이의 용도 및 사용 방법
CN105663081B (zh) * 2015-12-30 2019-08-02 大连医诺生物股份有限公司 微囊化β-丙氨酸
KR102108153B1 (ko) * 2017-07-05 2020-05-07 (주)동구바이오제약 생체 이용률 및 안정성이 개선된 레티노이드를 함유하는 약제학적 조성물
JP2020527140A (ja) 2017-07-12 2020-09-03 ソル − ゲル テクノロジーズ リミテッド カプセル化トレチノインを含む組成物
KR102218427B1 (ko) * 2017-09-20 2021-02-22 차의과학대학교 산학협력단 단백질 약물을 포함하는 코아세르베이트 조성물 및 이를 포함하는 창상 치료제
CN108451787B (zh) * 2018-05-23 2020-01-07 上海格兰化妆品有限公司 一种包埋维生素a醇的纳米脂质载体及其制备方法
CN111329851A (zh) * 2018-06-08 2020-06-26 中国医学科学院皮肤病医院 阿达帕林和抗增殖药物联合在制备预防或治疗血液系统肿瘤药物中的应用
CN114929678B (zh) * 2019-11-29 2023-08-15 石家庄迪斯凯威医药科技有限公司 一种取代的间三联苯类化合物及其药物组合物和用途
CN110917071B (zh) * 2019-12-23 2022-11-08 万华化学集团股份有限公司 核壳结构柔珠、其制备方法及包括其的个人护理用品
CN111378185B (zh) * 2020-03-31 2022-11-29 暨南大学 一种仿生蛋白多糖类纳米材料及其制备方法与应用
CN113818240A (zh) * 2021-09-23 2021-12-21 烟台明远创意生活科技股份有限公司 一种大麻二酚整理液及大麻二酚功能面料的整理工艺

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR512367A (fr) 1920-03-25 1921-01-21 Scott Motor Cycle Company Ltd Perfectionnements apportés aux fourches de roues
JPS5910642B2 (ja) * 1979-02-09 1984-03-10 田辺製薬株式会社 疎水性医薬物質含有マイクロカプセルおよびその製法
JPH01265007A (ja) * 1988-04-15 1989-10-23 Shiseido Co Ltd 外用剤
JPH02261534A (ja) * 1989-04-01 1990-10-24 Shiseido Co Ltd マイクロカプセル及びそれを配合した外用剤
GB9700624D0 (en) * 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
FR2861069B1 (fr) 2003-10-17 2005-12-09 Galderma Res & Dev NOUVEAUX LIGANDS ACTIVATEURS DES RECEPTEURS RARs, UTILISATION EN MEDECINE HUMAINE AINSI QU'EN COSMETIQUE
ES2317076T3 (es) 2003-12-08 2009-04-16 GALDERMA RESEARCH & DEVELOPMENT Derivados bifenilicos utiles como ligandos que activan receptores rar, procedimiento para prepararlos y su utilizacion en medicina humana y en cosmeticos.
CN1972675A (zh) * 2004-05-06 2007-05-30 伊夫雷亚医药公司 用于递送活性剂的粒子
CA2565236A1 (en) * 2004-05-06 2005-11-17 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents
FR2880020B1 (fr) * 2004-12-23 2007-02-16 Galderma Res & Dev NOUVEAUX LIGANDS MODULATEURS DES RECEPTEURS RARs, UTILISATION EN MEDECINE HUMAINE AINSI QU'EN COSMETIQUE
WO2006066978A1 (en) * 2004-12-23 2006-06-29 Galderma Research & Development Novel ligands that modulate rar receptors, and use thereof in human medicine and in cosmetics
FR2915682B1 (fr) * 2007-05-04 2009-07-03 Galderma Res & Dev Compositions depigmentantes dermatologiques et cosmetiques, leurs procedes de preparation, et leurs utilisations
BRPI0705823A2 (pt) * 2007-08-23 2009-04-14 Glenmark Pharmaceuticals Ltd composições farmacêuticas tópicas contendo microesferas de adapaleno
CN101288662B (zh) * 2008-05-09 2010-06-02 济南大学 一种叶黄素微胶囊及其制备方法
WO2009156679A1 (fr) * 2008-05-30 2009-12-30 Galderma Research & Development Compositions depigmentantes anhydres comprenant, au sein de la phase grasse un derive phenolique solubilise et un retinoide

Also Published As

Publication number Publication date
CA2874375A1 (fr) 2013-12-05
CN104661656A (zh) 2015-05-27
BR112014029869A2 (pt) 2019-08-20
AU2013269566A1 (en) 2015-01-15
US20150190372A1 (en) 2015-07-09
KR20150014522A (ko) 2015-02-06
JP2015518031A (ja) 2015-06-25
WO2013178743A1 (fr) 2013-12-05
FR2991172A1 (fr) 2013-12-06
RU2014152994A (ru) 2016-07-27
EP2854775A1 (fr) 2015-04-08

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