MX377669B - Derivados de aminoester. - Google Patents

Derivados de aminoester.

Info

Publication number
MX377669B
MX377669B MX2016015958A MX2016015958A MX377669B MX 377669 B MX377669 B MX 377669B MX 2016015958 A MX2016015958 A MX 2016015958A MX 2016015958 A MX2016015958 A MX 2016015958A MX 377669 B MX377669 B MX 377669B
Authority
MX
Mexico
Prior art keywords
sub
sup
buffer
edta
hci
Prior art date
Application number
MX2016015958A
Other languages
English (en)
Spanish (es)
Other versions
MX2016015958A (es
Inventor
Carmelida Capaldi
Charles Baker-Glenn
Elisabetta Armani
Gabriele Amari
De Pöel Hervé Van
Ian Linney
Naimisha Trivedi
Wesley Blackaby
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Publication of MX2016015958A publication Critical patent/MX2016015958A/es
Publication of MX377669B publication Critical patent/MX377669B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
MX2016015958A 2014-06-05 2015-06-03 Derivados de aminoester. MX377669B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14171266 2014-06-05
PCT/EP2015/062417 WO2015185649A1 (en) 2014-06-05 2015-06-03 Aminoester derivatives

Publications (2)

Publication Number Publication Date
MX2016015958A MX2016015958A (es) 2017-04-10
MX377669B true MX377669B (es) 2025-03-11

Family

ID=50884281

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016015958A MX377669B (es) 2014-06-05 2015-06-03 Derivados de aminoester.

Country Status (32)

Country Link
US (2) US9763924B2 (https=)
EP (1) EP3152201B1 (https=)
JP (1) JP2017516824A (https=)
KR (1) KR102420323B1 (https=)
CN (1) CN106459020B (https=)
AR (1) AR100732A1 (https=)
AU (1) AU2015270539B2 (https=)
BR (1) BR112016026725B1 (https=)
CA (1) CA2953198C (https=)
CL (1) CL2016003117A1 (https=)
CY (1) CY1120698T1 (https=)
DK (1) DK3152201T3 (https=)
EA (1) EA032761B1 (https=)
ES (1) ES2688826T3 (https=)
GE (2) GEAP201814338A (https=)
HR (1) HRP20181967T1 (https=)
HU (1) HUE042119T2 (https=)
IL (1) IL249325B (https=)
LT (1) LT3152201T (https=)
MA (1) MA39947B1 (https=)
MX (1) MX377669B (https=)
PE (1) PE20161557A1 (https=)
PH (1) PH12016502221A1 (https=)
PL (1) PL3152201T3 (https=)
PT (1) PT3152201T (https=)
RS (1) RS57787B1 (https=)
SG (1) SG11201610132RA (https=)
SI (1) SI3152201T1 (https=)
TN (1) TN2016000546A1 (https=)
TW (1) TW201625600A (https=)
WO (1) WO2015185649A1 (https=)
ZA (1) ZA201608331B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016177849A1 (en) 2015-05-07 2016-11-10 Chiesi Farmaceutici S.P.A. Aminoester derivatives
AR104829A1 (es) * 2015-06-01 2017-08-16 Chiesi Farm Spa Derivados de aminoésteres
AR104822A1 (es) * 2015-06-01 2017-08-16 Chiesi Farm Spa Derivado de aminoésteres
CN106866474B (zh) * 2017-02-16 2018-12-28 陕西师范大学 一种手性α-芳基甘氨酸酯衍生物的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2022783A1 (en) * 2007-08-08 2009-02-11 CHIESI FARMACEUTICI S.p.A. "Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors"
AR070562A1 (es) 2008-02-06 2010-04-21 Glaxo Group Ltd Farmacoforos duales - antagonistas muscarinicos de pde4
EP2216327A1 (en) * 2009-02-06 2010-08-11 CHIESI FARMACEUTICI S.p.A. Benzoic acid (1-phenyl-2-pyridin-4-yl)ethyl esters as phosphodiesterase inhibitors
HK1213245A1 (zh) 2012-12-05 2016-06-30 奇斯药制品公司 作为pde4抑制剂的苯乙基吡啶衍生物
HK1212988A1 (zh) 2012-12-05 2016-07-22 奇斯药制品公司 作为pde-4抑制剂的苯基乙基吡啶衍生物
WO2014086852A1 (en) 2012-12-05 2014-06-12 Chiesi Farmaceutici S.P.A. Phenylethylpyridine derivatives as pde4-inhibitors
RU2016121852A (ru) 2013-12-05 2017-12-07 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Производные бензгидрила для лечения респираторных заболеваний
US9133185B2 (en) 2013-12-05 2015-09-15 Chiesi Farmaceutici S.P.A Heteroaryl derivatives

Also Published As

Publication number Publication date
SG11201610132RA (en) 2017-01-27
EP3152201A1 (en) 2017-04-12
IL249325A0 (en) 2017-02-28
US20150352091A1 (en) 2015-12-10
WO2015185649A1 (en) 2015-12-10
BR112016026725B1 (pt) 2024-02-27
CN106459020B (zh) 2019-06-18
EA201692227A1 (ru) 2017-05-31
EP3152201B1 (en) 2018-08-29
AU2015270539B2 (en) 2018-11-08
HRP20181967T1 (hr) 2019-02-08
KR20170015294A (ko) 2017-02-08
BR112016026725A2 (pt) 2017-08-15
CY1120698T1 (el) 2019-12-11
CA2953198A1 (en) 2015-12-10
BR112016026725A8 (pt) 2021-06-29
ZA201608331B (en) 2018-05-30
WO2015185649A9 (en) 2017-01-05
US20170340616A1 (en) 2017-11-30
JP2017516824A (ja) 2017-06-22
PT3152201T (pt) 2018-10-26
EA032761B1 (ru) 2019-07-31
TN2016000546A1 (en) 2018-04-04
GEAP201814338A (en) 2018-07-25
PE20161557A1 (es) 2017-02-07
DK3152201T3 (en) 2018-11-19
LT3152201T (lt) 2018-10-10
MX2016015958A (es) 2017-04-10
CN106459020A (zh) 2017-02-22
IL249325B (en) 2018-12-31
MA39947A (fr) 2017-04-12
AR100732A1 (es) 2016-10-26
PL3152201T3 (pl) 2019-02-28
MA39947B1 (fr) 2018-10-31
KR102420323B1 (ko) 2022-07-13
AU2015270539A1 (en) 2016-12-22
US10117860B2 (en) 2018-11-06
GEP20186922B (en) 2018-11-12
US9763924B2 (en) 2017-09-19
CL2016003117A1 (es) 2017-06-23
TW201625600A (zh) 2016-07-16
CA2953198C (en) 2023-06-13
ES2688826T3 (es) 2018-11-07
RS57787B1 (sr) 2018-12-31
PH12016502221A1 (en) 2017-02-06
HUE042119T2 (hu) 2019-06-28
SI3152201T1 (sl) 2018-10-30

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