BR112016026725A2 - Derivados de aminoéster - Google Patents

Derivados de aminoéster

Info

Publication number
BR112016026725A2
BR112016026725A2 BR112016026725A BR112016026725A BR112016026725A2 BR 112016026725 A2 BR112016026725 A2 BR 112016026725A2 BR 112016026725 A BR112016026725 A BR 112016026725A BR 112016026725 A BR112016026725 A BR 112016026725A BR 112016026725 A2 BR112016026725 A2 BR 112016026725A2
Authority
BR
Brazil
Prior art keywords
aminoester derivatives
aminoester
derivatives
Prior art date
Application number
BR112016026725A
Other languages
English (en)
Other versions
BR112016026725A8 (pt
BR112016026725B1 (pt
Inventor
Capaldi Carmelida
Baker-Glenn Charles
Armani Elisabetta
Amari Gabriele
Van De Pöel Hervé
Linney Ian
Trivedi Naimisha
Blackaby Wesley
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Publication of BR112016026725A2 publication Critical patent/BR112016026725A2/pt
Publication of BR112016026725A8 publication Critical patent/BR112016026725A8/pt
Publication of BR112016026725B1 publication Critical patent/BR112016026725B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
BR112016026725-7A 2014-06-05 2015-06-03 Derivados de aminoéster BR112016026725B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14171266 2014-06-05
EP14171266.1 2014-06-05
PCT/EP2015/062417 WO2015185649A1 (en) 2014-06-05 2015-06-03 Aminoester derivatives

Publications (3)

Publication Number Publication Date
BR112016026725A2 true BR112016026725A2 (pt) 2017-08-15
BR112016026725A8 BR112016026725A8 (pt) 2021-06-29
BR112016026725B1 BR112016026725B1 (pt) 2024-02-27

Family

ID=50884281

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016026725-7A BR112016026725B1 (pt) 2014-06-05 2015-06-03 Derivados de aminoéster

Country Status (32)

Country Link
US (2) US9763924B2 (pt)
EP (1) EP3152201B1 (pt)
JP (1) JP2017516824A (pt)
KR (1) KR102420323B1 (pt)
CN (1) CN106459020B (pt)
AR (1) AR100732A1 (pt)
AU (1) AU2015270539B2 (pt)
BR (1) BR112016026725B1 (pt)
CA (1) CA2953198C (pt)
CL (1) CL2016003117A1 (pt)
CY (1) CY1120698T1 (pt)
DK (1) DK3152201T3 (pt)
EA (1) EA032761B1 (pt)
ES (1) ES2688826T3 (pt)
GE (1) GEP20186922B (pt)
HR (1) HRP20181967T1 (pt)
HU (1) HUE042119T2 (pt)
IL (1) IL249325B (pt)
LT (1) LT3152201T (pt)
MA (1) MA39947B1 (pt)
MX (1) MX2016015958A (pt)
PE (1) PE20161557A1 (pt)
PH (1) PH12016502221A1 (pt)
PL (1) PL3152201T3 (pt)
PT (1) PT3152201T (pt)
RS (1) RS57787B1 (pt)
SG (1) SG11201610132RA (pt)
SI (1) SI3152201T1 (pt)
TN (1) TN2016000546A1 (pt)
TW (1) TW201625600A (pt)
WO (1) WO2015185649A1 (pt)
ZA (1) ZA201608331B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016177849A1 (en) 2015-05-07 2016-11-10 Chiesi Farmaceutici S.P.A. Aminoester derivatives
AR104829A1 (es) * 2015-06-01 2017-08-16 Chiesi Farm Spa Derivados de aminoésteres
AR104822A1 (es) * 2015-06-01 2017-08-16 Chiesi Farm Spa Derivado de aminoésteres
CN106866474B (zh) * 2017-02-16 2018-12-28 陕西师范大学 一种手性α-芳基甘氨酸酯衍生物的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2022783A1 (en) * 2007-08-08 2009-02-11 CHIESI FARMACEUTICI S.p.A. "Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors"
UY31637A1 (es) 2008-02-06 2009-08-03 Farmacoforos duales-antagonistas muscarinicos de pde4
EP2216327A1 (en) * 2009-02-06 2010-08-11 CHIESI FARMACEUTICI S.p.A. Benzoic acid (1-phenyl-2-pyridin-4-yl)ethyl esters as phosphodiesterase inhibitors
TW201439089A (zh) 2012-12-05 2014-10-16 Chiesi Farma Spa 新穎化合物
TW201434817A (zh) * 2012-12-05 2014-09-16 Chiesi Farma Spa 新穎化合物
BR112015012949A2 (pt) 2012-12-05 2017-07-11 Chiesi Farm Spa composto, composição farmaceutica, uso de um composto, dispositivo inalatório e kit
CA2932486A1 (en) 2013-12-05 2015-06-11 Chiesi Farmaceutici S.P.A. Benzhydryl derivatives for the treatment of respiratory diseases
KR20160086351A (ko) * 2013-12-05 2016-07-19 키에시 파르마슈티시 엣스. 피. 에이. 호흡기 질환의 치료를 위한 헤테로아릴 유도체

Also Published As

Publication number Publication date
EP3152201B1 (en) 2018-08-29
US9763924B2 (en) 2017-09-19
IL249325A0 (en) 2017-02-28
US20150352091A1 (en) 2015-12-10
JP2017516824A (ja) 2017-06-22
PH12016502221A1 (en) 2017-02-06
BR112016026725A8 (pt) 2021-06-29
PT3152201T (pt) 2018-10-26
GEP20186922B (en) 2018-11-12
MA39947B1 (fr) 2018-10-31
CL2016003117A1 (es) 2017-06-23
AU2015270539A1 (en) 2016-12-22
TN2016000546A1 (en) 2018-04-04
SI3152201T1 (sl) 2018-10-30
US10117860B2 (en) 2018-11-06
SG11201610132RA (en) 2017-01-27
ES2688826T3 (es) 2018-11-07
TW201625600A (zh) 2016-07-16
KR102420323B1 (ko) 2022-07-13
CA2953198C (en) 2023-06-13
PL3152201T3 (pl) 2019-02-28
RS57787B1 (sr) 2018-12-31
LT3152201T (lt) 2018-10-10
CA2953198A1 (en) 2015-12-10
KR20170015294A (ko) 2017-02-08
BR112016026725B1 (pt) 2024-02-27
MA39947A (fr) 2017-04-12
ZA201608331B (en) 2018-05-30
HUE042119T2 (hu) 2019-06-28
WO2015185649A1 (en) 2015-12-10
CN106459020A (zh) 2017-02-22
EA201692227A1 (ru) 2017-05-31
EA032761B1 (ru) 2019-07-31
AR100732A1 (es) 2016-10-26
IL249325B (en) 2018-12-31
MX2016015958A (es) 2017-04-10
AU2015270539B2 (en) 2018-11-08
US20170340616A1 (en) 2017-11-30
CN106459020B (zh) 2019-06-18
HRP20181967T1 (hr) 2019-02-08
DK3152201T3 (en) 2018-11-19
EP3152201A1 (en) 2017-04-12
WO2015185649A9 (en) 2017-01-05
CY1120698T1 (el) 2019-12-11
PE20161557A1 (es) 2017-02-07

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/06/2015, OBSERVADAS AS CONDICOES LEGAIS

B16D Grant of patent or certificate of addition of invention cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 16.1 NA RPI NO 2773 DE 27/02/2024 POR TER SIDO INDEVIDA.

B09X Republication of the decision to grant [chapter 9.1.3 patent gazette]