MX377377B - Composiciones tópicas para el alivio del dolor, manufactura y uso. - Google Patents

Composiciones tópicas para el alivio del dolor, manufactura y uso.

Info

Publication number
MX377377B
MX377377B MX2016013280A MX2016013280A MX377377B MX 377377 B MX377377 B MX 377377B MX 2016013280 A MX2016013280 A MX 2016013280A MX 2016013280 A MX2016013280 A MX 2016013280A MX 377377 B MX377377 B MX 377377B
Authority
MX
Mexico
Prior art keywords
pain relief
manufacture
topical compositions
methods
compositions
Prior art date
Application number
MX2016013280A
Other languages
English (en)
Other versions
MX2016013280A (es
Inventor
Daniel Bucks
Philip J Birbara
Original Assignee
Propella Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Propella Therapeutics Inc filed Critical Propella Therapeutics Inc
Publication of MX2016013280A publication Critical patent/MX2016013280A/es
Publication of MX377377B publication Critical patent/MX377377B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a composiciones agonistas selectivas de TRPV1 que incluyen un capsaicinoide, un surfactante y un agente de liberación prolongada, y a métodos de manufactura y métodos para proporcionar alivio del dolor así como también para tratar una variedad de trastornos con estas composiciones.
MX2016013280A 2014-04-15 2015-04-15 Composiciones tópicas para el alivio del dolor, manufactura y uso. MX377377B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461979905P 2014-04-15 2014-04-15
PCT/US2015/025957 WO2015160941A1 (en) 2014-04-15 2015-04-15 Topical compositions for pain relief, manufacture and use

Publications (2)

Publication Number Publication Date
MX2016013280A MX2016013280A (es) 2017-04-27
MX377377B true MX377377B (es) 2025-03-10

Family

ID=53008908

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016013280A MX377377B (es) 2014-04-15 2015-04-15 Composiciones tópicas para el alivio del dolor, manufactura y uso.

Country Status (9)

Country Link
US (6) US9956190B2 (es)
EP (1) EP3131531B1 (es)
JP (1) JP6563954B2 (es)
KR (1) KR102073258B1 (es)
AU (1) AU2015247649B2 (es)
BR (1) BR112016023815A2 (es)
CA (1) CA2945818C (es)
MX (1) MX377377B (es)
WO (1) WO2015160941A1 (es)

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GB2525517B (en) 2012-12-07 2019-12-04 Sambria Pharmaceuticals Llc Topical preparation for pain relief
US10265283B2 (en) 2012-12-07 2019-04-23 Sambria Pharmaceuticals, Llc Topical composition and delivery system and its use
US9956190B2 (en) 2014-04-15 2018-05-01 Vizuri Health Sciences Llc Topical compositions for pain relief, manufacture and use
GB2564026B (en) * 2016-02-03 2022-07-13 Sbg Medical Tech Inc Topical composition and delivery system and its use
AU2017353782B2 (en) 2016-11-02 2022-06-02 Centrexion Therapeutics Corporation Stable aqueous capsaicin injectable formulations and medical uses thereof
JP2020500220A (ja) 2016-11-15 2020-01-09 クラリア ファーマ ホールディング エービー 医薬製剤
US10918685B2 (en) * 2017-01-05 2021-02-16 Ravi Ramamoorthy Iyer Herbal topical composition for muscle and joint health, recovery from exertion, and for pain management
GB201709141D0 (en) 2017-06-08 2017-07-26 Klaria Pharma Holding Ab Pharmaceutical formulation
BR112020000989A2 (pt) 2017-07-20 2020-07-14 Centrexion Therapeutics Corporation métodos e composições para tratamento de dor com o uso de capsaicina
GB201808462D0 (en) 2018-05-23 2018-07-11 Klaria Pharma Holding Ab Pharmaceutical formulation
US11254659B1 (en) 2019-01-18 2022-02-22 Centrexion Therapeutics Corporation Capsaicinoid prodrug compounds and their use in treating medical conditions
US11447444B1 (en) 2019-01-18 2022-09-20 Centrexion Therapeutics Corporation Capsaicinoid prodrug compounds and their use in treating medical conditions
JP2020152674A (ja) * 2019-03-20 2020-09-24 株式会社リコー 難水溶性化合物の可溶化物の製造方法
CN115297853A (zh) 2020-03-17 2022-11-04 格吕伦塔尔有限公司 用于治疗初始无反应者的辣椒素贴剂的重复局部敷用
EP4125841A1 (en) 2020-04-03 2023-02-08 Grünenthal GmbH Regimen for repeated topical application of capsaicin patch
US12268663B2 (en) * 2020-10-03 2025-04-08 Pruvyc Pharma, LLC Method for treating pruritus
MX2024007092A (es) 2021-12-17 2024-06-26 Aerie Pharmaceuticals Inc Composiciones farmaceuticas oftalmicas y usos de las mismas.
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US20250228815A1 (en) 2024-01-15 2025-07-17 Gruenenthal Gmbh Lyophilized resiniferatoxin
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Also Published As

Publication number Publication date
KR102073258B1 (ko) 2020-02-04
US20180214397A1 (en) 2018-08-02
US11123315B2 (en) 2021-09-21
US20180214398A1 (en) 2018-08-02
US20190247337A1 (en) 2019-08-15
CA2945818A1 (en) 2015-10-22
AU2015247649A1 (en) 2016-11-03
AU2015247649B2 (en) 2019-01-17
US10583100B2 (en) 2020-03-10
US20150290151A1 (en) 2015-10-15
US10206892B2 (en) 2019-02-19
US20200323800A1 (en) 2020-10-15
US20220168247A1 (en) 2022-06-02
EP3131531B1 (en) 2022-04-06
US9956190B2 (en) 2018-05-01
WO2015160941A1 (en) 2015-10-22
US11737994B2 (en) 2023-08-29
JP2017511366A (ja) 2017-04-20
JP6563954B2 (ja) 2019-08-21
BR112016023815A2 (pt) 2017-08-15
MX2016013280A (es) 2017-04-27
KR20160145628A (ko) 2016-12-20
EP3131531A1 (en) 2017-02-22
US10085956B2 (en) 2018-10-02
CA2945818C (en) 2022-05-03

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Owner name: PROPELLA THERAPEUTICS, INC.