GB2564026B - Topical composition and delivery system and its use - Google Patents

Topical composition and delivery system and its use Download PDF

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Publication number
GB2564026B
GB2564026B GB1814047.5A GB201814047A GB2564026B GB 2564026 B GB2564026 B GB 2564026B GB 201814047 A GB201814047 A GB 201814047A GB 2564026 B GB2564026 B GB 2564026B
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GB
United Kingdom
Prior art keywords
delivery system
topical composition
topical
composition
delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1814047.5A
Other versions
GB201814047D0 (en
GB2564026A (en
Inventor
Harvey Greenspan Michael
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SBG Medical Technologies Inc
Original Assignee
SBG Medical Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/014,988 external-priority patent/US10265283B2/en
Application filed by SBG Medical Technologies Inc filed Critical SBG Medical Technologies Inc
Priority to GB2201845.1A priority Critical patent/GB2600651A/en
Publication of GB201814047D0 publication Critical patent/GB201814047D0/en
Publication of GB2564026A publication Critical patent/GB2564026A/en
Application granted granted Critical
Publication of GB2564026B publication Critical patent/GB2564026B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
GB1814047.5A 2016-02-03 2016-02-04 Topical composition and delivery system and its use Active GB2564026B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2201845.1A GB2600651A (en) 2016-02-03 2016-02-04 Topical composition and delivery system and its use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/014,988 US10265283B2 (en) 2012-12-07 2016-02-03 Topical composition and delivery system and its use
PCT/US2016/016517 WO2017135948A1 (en) 2016-02-03 2016-02-04 Topical composition and delivery system and its use

Publications (3)

Publication Number Publication Date
GB201814047D0 GB201814047D0 (en) 2018-10-10
GB2564026A GB2564026A (en) 2019-01-02
GB2564026B true GB2564026B (en) 2022-07-13

Family

ID=59499809

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1814047.5A Active GB2564026B (en) 2016-02-03 2016-02-04 Topical composition and delivery system and its use
GB2201845.1A Withdrawn GB2600651A (en) 2016-02-03 2016-02-04 Topical composition and delivery system and its use

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB2201845.1A Withdrawn GB2600651A (en) 2016-02-03 2016-02-04 Topical composition and delivery system and its use

Country Status (3)

Country Link
CA (1) CA3013567C (en)
GB (2) GB2564026B (en)
WO (1) WO2017135948A1 (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070243132A1 (en) * 2005-12-22 2007-10-18 Apollo Life Sciences Limited Transdermal delivery of pharmaceutical agents
US20070269379A1 (en) * 2003-07-23 2007-11-22 Samir Mitragotri Penetration Enhancer Combinations for Transdermal Delivery
US20080154210A1 (en) * 2004-05-28 2008-06-26 Oryxe Mixture for Transdermal Delivery of Low and High Molecular Weight Compounds
US20130337031A1 (en) * 2006-03-06 2013-12-19 Nuvo Research Inc. Topical formulations, systems and methods
WO2014089381A1 (en) * 2012-12-07 2014-06-12 Sambria Pharmaceuticals, Llc Topical preparation for pain relief
WO2014130761A2 (en) * 2013-02-22 2014-08-28 President And Fellows Of Harvard College Nanostructured active therapeutic vehicles and uses thereof
WO2014176417A1 (en) * 2013-04-24 2014-10-30 Sambria Pharmaceuticals, Llc Topical preparation for bypassing gi tract, delivery of therapeutics, and trans-epithelial drug delivery system
US20150290151A1 (en) * 2014-04-15 2015-10-15 Vizuri Health Sciences Llc Topical compositions for pain relief, manufacture and use

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070269379A1 (en) * 2003-07-23 2007-11-22 Samir Mitragotri Penetration Enhancer Combinations for Transdermal Delivery
US20080154210A1 (en) * 2004-05-28 2008-06-26 Oryxe Mixture for Transdermal Delivery of Low and High Molecular Weight Compounds
US20070243132A1 (en) * 2005-12-22 2007-10-18 Apollo Life Sciences Limited Transdermal delivery of pharmaceutical agents
US20130337031A1 (en) * 2006-03-06 2013-12-19 Nuvo Research Inc. Topical formulations, systems and methods
WO2014089381A1 (en) * 2012-12-07 2014-06-12 Sambria Pharmaceuticals, Llc Topical preparation for pain relief
US20140163105A1 (en) * 2012-12-07 2014-06-12 Michael Harvey Greenspan Topical preparation for pain relief
WO2014130761A2 (en) * 2013-02-22 2014-08-28 President And Fellows Of Harvard College Nanostructured active therapeutic vehicles and uses thereof
WO2014176417A1 (en) * 2013-04-24 2014-10-30 Sambria Pharmaceuticals, Llc Topical preparation for bypassing gi tract, delivery of therapeutics, and trans-epithelial drug delivery system
US20150290151A1 (en) * 2014-04-15 2015-10-15 Vizuri Health Sciences Llc Topical compositions for pain relief, manufacture and use

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Amazon, 2021, NeuroMed7® 2.2 Ounce Tube, amazon.com, [online] Available from https://www.amazon.com/NeuroMed-7-NeuroMed7-lidocaine-cream/dp/B00T3N1O82 [Accessed 14 July 2021] *
Wayback machine, 28 April 2015, Neuromed 7 Topical Pain Relief - lidocaine hydrochloride cream, Internet Archive, [online] Available from https://web.archive.org/web/20150428014731/https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f199f56b-d971-4cf8-834d-babb5c2ff81a [Accessed 14 July 2021] *
Youtube, 9 November 2015, NeuroMed7 | Topical Anesthetic | 888.246.6601, youtube.com, [online], Available from NeuroMed7 | Topical Anesthetic | 888.246.6601 - YouTube [Accessed 25 November 2021] *

Also Published As

Publication number Publication date
GB202201845D0 (en) 2022-03-30
CA3013567C (en) 2023-09-05
CA3013567A1 (en) 2017-08-10
WO2017135948A1 (en) 2017-08-10
GB2600651A (en) 2022-05-04
GB201814047D0 (en) 2018-10-10
GB2564026A (en) 2019-01-02

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