MX375586B - Metodo para diagnosticar cancer colorrectal a partir de una muestra de heces humanas por pcr cuantitativa, cebadores y equipo. - Google Patents

Metodo para diagnosticar cancer colorrectal a partir de una muestra de heces humanas por pcr cuantitativa, cebadores y equipo.

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Publication number
MX375586B
MX375586B MX2016011377A MX2016011377A MX375586B MX 375586 B MX375586 B MX 375586B MX 2016011377 A MX2016011377 A MX 2016011377A MX 2016011377 A MX2016011377 A MX 2016011377A MX 375586 B MX375586 B MX 375586B
Authority
MX
Mexico
Prior art keywords
colorectal cancer
diagnostics
primers
equipment
quantitative pcr
Prior art date
Application number
MX2016011377A
Other languages
English (en)
Other versions
MX2016011377A (es
Inventor
Jesús García-Gil
PAGÉS Mariona SERRA
De Xaxars Teresa Mas
Xavier Aldeguer
Original Assignee
Univ Girona
Fundacio Inst Dinvestigacio Biomedica De Girona Dr Josep Trueta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Girona, Fundacio Inst Dinvestigacio Biomedica De Girona Dr Josep Trueta filed Critical Univ Girona
Publication of MX2016011377A publication Critical patent/MX2016011377A/es
Publication of MX375586B publication Critical patent/MX375586B/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se relaciona con el campo de la detección de cáncer colorrectal (CRC). Específicamente, se relaciona con métodos para la detección temprana, análisis selectivo de riesgos y monitoreo de CRC y/o pólipos adenomatosos en un sujeto humano, con base en la cuantificación de una o más secuencias bacterianas de rDNA 16S en las heces. Además se relaciona con el uso de estas secuencias bacterianas como biomarcadores del cáncer colorrectal y/o pólipos adenomatosos, con un equipo que comprende un reactivo e instrucciones para la cuantificación de las secuencias bacterianas, y con ácidos nucleicos para la cuantificación de las secuencias bacterianas de rDNA 16S.
MX2016011377A 2014-03-03 2015-03-03 Metodo para diagnosticar cancer colorrectal a partir de una muestra de heces humanas por pcr cuantitativa, cebadores y equipo. MX375586B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14382074.4A EP2915884B1 (en) 2014-03-03 2014-03-03 Method for diagnosing colorectal cancer from a human feces sample by quantitive PCR
PCT/EP2015/054451 WO2015132273A1 (en) 2014-03-03 2015-03-03 Method for diagnosing colorectal cancer from a human feces sample by quantitive pcr, primers and kit

Publications (2)

Publication Number Publication Date
MX2016011377A MX2016011377A (es) 2017-05-04
MX375586B true MX375586B (es) 2025-03-06

Family

ID=50241352

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016011377A MX375586B (es) 2014-03-03 2015-03-03 Metodo para diagnosticar cancer colorrectal a partir de una muestra de heces humanas por pcr cuantitativa, cebadores y equipo.

Country Status (17)

Country Link
US (1) US10927416B2 (es)
EP (2) EP2915884B1 (es)
JP (2) JP7053146B2 (es)
KR (1) KR102354660B1 (es)
CN (1) CN106574294A (es)
AU (1) AU2015226203B2 (es)
CA (1) CA2941502C (es)
DK (1) DK3114234T3 (es)
ES (2) ES2661684T3 (es)
HR (1) HRP20191108T1 (es)
IL (1) IL247370B (es)
MX (1) MX375586B (es)
PT (1) PT3114234T (es)
RU (1) RU2692555C2 (es)
SI (1) SI3114234T1 (es)
TR (1) TR201909533T4 (es)
WO (1) WO2015132273A1 (es)

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* Cited by examiner, † Cited by third party
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EP3130680A1 (en) * 2015-08-11 2017-02-15 Universitat de Girona Method for the detection, follow up and/or classification of intestinal diseases
CN105543354B (zh) 2015-12-31 2019-07-26 广州市康立明生物科技有限责任公司 一种肿瘤分子检测/诊断试剂
WO2017172894A2 (en) * 2016-03-30 2017-10-05 The Trustees Of Columbia University In The City Of New York Methods of preventing, treating and detecting colorectal cancer using butyrate producing bacteria
CN108690864A (zh) * 2017-10-31 2018-10-23 中山大学 一种粪便样本中菌群稳态评价方法及在结直肠癌筛查中的应用
KR102282490B1 (ko) * 2018-01-12 2021-07-28 주식회사 엠디헬스케어 패칼리박테리움 프라우스니찌 유래 나노소포 및 이의 용도
WO2019226035A1 (ko) * 2018-05-25 2019-11-28 주식회사 엠디헬스케어 Qpcr 분석을 통한 대장암 진단방법
CN110857450B (zh) * 2018-08-22 2023-04-07 深圳华大生命科学研究院 结直肠癌标志物及其应用
EP3874068A4 (en) * 2018-11-02 2022-08-17 The Regents of the University of California METHODS OF DIAGNOSIS AND TREATMENT OF CANCER USING NON-HUMAN NUCLEIC ACIDS
CA3132912A1 (en) 2019-03-13 2020-09-17 Goodgut S.L. Improved method for the screening, diagnosis and/or monitoring of colorectal advanced neoplasia, advanced adenoma and/or colorectal cancer
CN113906130A (zh) * 2019-03-28 2022-01-07 千实验室株式会社 粪杆菌属微生物及包含其的抗癌组合物
WO2020237238A1 (en) * 2019-05-23 2020-11-26 American Molecular Laboratories, Inc. Methods for detection of rare dna sequences in fecal samples
KR102308931B1 (ko) * 2019-05-24 2021-10-06 주식회사 엠디헬스케어 qPCR 분석을 통한 대장염 진단방법
CN111500732A (zh) * 2020-05-25 2020-08-07 福建医科大学 微生物在作为子宫内膜癌的诊断标志物中的应用和试剂盒
CN113106163B (zh) 2020-05-27 2024-06-04 微度(苏州)生物科技有限公司 一种用于结直肠癌早期诊断的生物标志物组合物及应用
CN112048564A (zh) * 2020-08-11 2020-12-08 康美华大基因技术有限公司 一种快速检测瘤胃球菌的荧光定量pcr引物组、试剂盒及其应用
CN114107527A (zh) * 2021-12-10 2022-03-01 中国药科大学 用于检测丁酰辅酶a脱氢酶基因的引物对及试剂盒
CN115261271B (zh) * 2022-08-01 2023-12-12 厦门承葛生物科技有限公司 一种肠道菌群的高通量分离培养与筛选方法
CN115963268B (zh) * 2023-02-14 2023-09-19 浙江大学 一种用于结直肠癌早期诊断的血浆分泌蛋白组合及应用
CN117051113B (zh) * 2023-10-12 2023-12-29 上海爱谱蒂康生物科技有限公司 生物标志物组合在制备预测结直肠癌的试剂盒中的应用

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US6054278A (en) 1997-05-05 2000-04-25 The Perkin-Elmer Corporation Ribosomal RNA gene polymorphism based microorganism identification
WO2001023608A2 (en) * 1999-09-27 2001-04-05 Merck Sharp & Dohme De Espana, S.A.E. Hybridization probes which specifically detect strains of the genera microbispora, microtetraspora, nonomuria and planobispora
JPWO2009057695A1 (ja) 2007-10-30 2011-03-10 オリンパス株式会社 遺伝子解析による腺腫又はがんの検出方法
JP2009165401A (ja) * 2008-01-16 2009-07-30 Olympus Corp 標的物質の定量方法
CN102105583A (zh) 2008-07-23 2011-06-22 奥林巴斯株式会社 从粪便试样中回收核酸的方法、核酸分析方法以及粪便试样处理装置
US20140171339A1 (en) * 2011-06-06 2014-06-19 The University Of North Carolina At Chapel Hill Methods and kits for detecting adenomas, colorectal cancer, and uses thereof
KR20150134356A (ko) * 2013-03-05 2015-12-01 리엑스유니버시테이트 그로닝겐 염증을 억제하기 위한 페칼리 박테리움 프라우스니치이 htf-f (dsm 26943)의 용도
WO2014138999A1 (en) * 2013-03-14 2014-09-18 University Of Ottawa Methods for the diagnosis and treatment of inflammatory bowel disease
CN105473738B (zh) * 2013-08-06 2018-09-21 深圳华大基因科技有限公司 结直肠癌生物标志物

Also Published As

Publication number Publication date
ES2734143T3 (es) 2019-12-04
EP3114234A1 (en) 2017-01-11
RU2692555C2 (ru) 2019-06-25
KR102354660B1 (ko) 2022-01-24
JP7053146B2 (ja) 2022-04-12
JP2017508464A (ja) 2017-03-30
US20170096709A1 (en) 2017-04-06
EP2915884B1 (en) 2017-12-06
RU2016138766A (ru) 2018-04-03
EP3114234B1 (en) 2019-04-24
DK3114234T3 (da) 2019-07-15
EP2915884A1 (en) 2015-09-09
US10927416B2 (en) 2021-02-23
SI3114234T1 (sl) 2019-09-30
IL247370B (en) 2020-07-30
AU2015226203A1 (en) 2016-10-20
AU2015226203B2 (en) 2020-11-12
CA2941502C (en) 2023-09-26
CA2941502A1 (en) 2015-09-11
WO2015132273A1 (en) 2015-09-11
ES2661684T3 (es) 2018-04-03
MX2016011377A (es) 2017-05-04
JP2020146052A (ja) 2020-09-17
TR201909533T4 (tr) 2019-07-22
KR20170028296A (ko) 2017-03-13
HRP20191108T1 (hr) 2019-09-20
PT3114234T (pt) 2019-07-12
IL247370A0 (en) 2016-11-30
RU2016138766A3 (es) 2018-04-03
CN106574294A (zh) 2017-04-19

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