MX359616B - Metodo y aparato para deteccion electroquimica. - Google Patents

Metodo y aparato para deteccion electroquimica.

Info

Publication number
MX359616B
MX359616B MX2010004465A MX2010004465A MX359616B MX 359616 B MX359616 B MX 359616B MX 2010004465 A MX2010004465 A MX 2010004465A MX 2010004465 A MX2010004465 A MX 2010004465A MX 359616 B MX359616 B MX 359616B
Authority
MX
Mexico
Prior art keywords
electrochemical detection
sensor
anticoagulants
assays
directed
Prior art date
Application number
MX2010004465A
Other languages
English (en)
Other versions
MX2010004465A (es
Inventor
Peter Michael Newman
Alastair M Hodges
Original Assignee
Universal Biosensors Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universal Biosensors Pty Ltd filed Critical Universal Biosensors Pty Ltd
Publication of MX2010004465A publication Critical patent/MX2010004465A/es
Publication of MX359616B publication Critical patent/MX359616B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273—Devices therefor, e.g. test element readers, circuitry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/021—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance before and after chemical transformation of the material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G01N2021/4776—Miscellaneous in diffuse reflection devices
    • G01N2021/478—Application in testing analytical test strips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ecology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La presente invención se refiere a un detector opuesto, caracterizado porque comprende un electrodo de trabajo, un contraelectrodo, un reactivo para iniciar la coagulación, y un sustrato electroquímico, en donde el reactivo para iniciar la coagulación está recubierto sobre uno de los electrodos y el sustrato de trombina electroquímico está recubierto sobre el otro electrodo, en donde el detector detecta la escisión del ustrato electroquímico.
MX2010004465A 2007-10-26 2008-10-25 Metodo y aparato para deteccion electroquimica. MX359616B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98302907P 2007-10-26 2007-10-26
PCT/IB2008/002849 WO2009053834A1 (en) 2007-10-26 2008-10-25 Apparatus and method for electrochemical detection

Publications (2)

Publication Number Publication Date
MX2010004465A MX2010004465A (es) 2010-10-25
MX359616B true MX359616B (es) 2018-10-03

Family

ID=40579126

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010004465A MX359616B (es) 2007-10-26 2008-10-25 Metodo y aparato para deteccion electroquimica.

Country Status (21)

Country Link
US (1) US20100252452A1 (es)
EP (1) EP2210085B1 (es)
JP (2) JP6147463B2 (es)
KR (3) KR20100087181A (es)
CN (1) CN102232185B (es)
AU (1) AU2008315677B2 (es)
CA (1) CA2704126C (es)
CY (1) CY1117095T1 (es)
DK (1) DK2210085T3 (es)
ES (1) ES2557933T3 (es)
HU (1) HUE026083T2 (es)
IL (1) IL205315A (es)
MX (1) MX359616B (es)
NZ (1) NZ585031A (es)
PL (1) PL2210085T3 (es)
PT (1) PT2210085E (es)
SG (1) SG171582A1 (es)
SI (1) SI2210085T1 (es)
TW (1) TWI516601B (es)
WO (1) WO2009053834A1 (es)
ZA (1) ZA201002856B (es)

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TWI539157B (zh) 2011-11-15 2016-06-21 五鼎生物技術股份有限公司 電化學血液檢測試片及其診斷系統
CA2898201C (en) 2012-01-16 2023-09-26 Abram Scientific, Inc. Methods, devices, and systems for measuring physical properties of fluid
US9291612B2 (en) * 2012-07-16 2016-03-22 Micropoint Bioscience, Inc. Determining blood coagulation characteristics using residual accumulative conductive energy
US20150176049A1 (en) 2013-12-23 2015-06-25 Cilag Gmbh International Determining usability of analytical test strip
AU2014373646B2 (en) * 2014-01-01 2019-07-04 Digital Diagnostics Pty. Ltd System and method for detecting and monitoring proteolysis of protein matrices
WO2015183792A1 (en) * 2014-05-27 2015-12-03 Case Western Reserve University Electrochemical sensor for analyte detection
US9995701B2 (en) 2014-06-02 2018-06-12 Case Western Reserve University Capacitive sensing apparatuses, systems and methods of making same
US9921232B2 (en) 2014-09-26 2018-03-20 Abbott Point Of Care Inc. Ellagic acid formulations for use in coagulation assays
WO2016049527A1 (en) 2014-09-26 2016-03-31 Abbott Point Of Care Inc. Cartridge device with segmented fluidics for assaying coagulation in fluid samples
US10247741B2 (en) 2014-09-26 2019-04-02 Abbott Point Of Care Inc. Microfabricated device with micro-environment sensors for assaying coagulation in fluid samples
CN106999932A (zh) 2014-09-26 2017-08-01 雅培医护站股份有限公司 用于流体样本中的凝结测定的具有流体结的盒设备
CN107107057B (zh) 2014-09-26 2020-12-15 雅培医护站股份有限公司 用于流体样本中的凝结测定的盒设备识别
CN107107056B (zh) 2014-09-26 2020-04-14 雅培医护站股份有限公司 用于流体样本中的凝结测定的单通道盒设备
ES2881861T3 (es) 2014-09-26 2021-11-30 Abbott Point Of Care Inc Sensores para evaluar la coagulación en muestras de fluidos
BR112017011033B1 (pt) 2014-12-19 2021-12-14 F. Hoffmann-La Roche Ag Sistema para determinar pelo menos uma propriedade de uma amostra e método para determinar pelo menos uma propriedade de uma amostra
EP3403080A4 (en) 2016-01-15 2019-09-04 Case Western Reserve University DIELECTRIC DETECTION FOR SAMPLE CHARACTERIZATION
US11175252B2 (en) 2016-01-15 2021-11-16 Case Western Reserve University Dielectric sensing for blood characterization
CN106680339A (zh) * 2016-12-28 2017-05-17 北京乐普医疗科技有限责任公司 一种基于电化学方法的凝血酶原时间测试卡及其制备方法
US11162934B2 (en) 2017-03-15 2021-11-02 California Institute Of Technology Smart bandage
US20180328877A1 (en) * 2017-05-11 2018-11-15 Medtronic Minimed, Inc. Analyte sensors and methods for fabricating analyte sensors
JP7393006B2 (ja) 2018-01-25 2023-12-06 ペンタファーム アーゲー フィブリノーゲン検査
CN108398470B (zh) * 2018-04-13 2024-01-30 广州万孚生物技术股份有限公司 血液活化凝血时间测定生物传感器及其制作方法
US11774388B2 (en) 2019-04-02 2023-10-03 Case Western Reserve University Dielectric sensing to characterize hemostatic dysfunction
US11408844B2 (en) 2019-04-02 2022-08-09 Case Western Reserve University Dielectric sensing to characterize hemostatic dysfunction

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Also Published As

Publication number Publication date
CN102232185B (zh) 2016-08-03
ES2557933T3 (es) 2016-01-29
DK2210085T3 (en) 2016-01-11
SI2210085T1 (sl) 2016-04-29
JP2011501181A (ja) 2011-01-06
CY1117095T1 (el) 2017-04-05
WO2009053834A1 (en) 2009-04-30
IL205315A0 (en) 2010-12-30
NZ585031A (en) 2012-12-21
SG171582A1 (en) 2011-06-29
TW200942619A (en) 2009-10-16
EP2210085B1 (en) 2015-09-30
EP2210085A1 (en) 2010-07-28
JP6147463B2 (ja) 2017-06-14
CA2704126C (en) 2017-07-25
MX2010004465A (es) 2010-10-25
KR101854883B1 (ko) 2018-05-04
ZA201002856B (en) 2011-03-30
HUE026083T2 (en) 2016-05-30
AU2008315677A1 (en) 2009-04-30
PT2210085E (pt) 2016-01-29
IL205315A (en) 2016-11-30
KR20170038945A (ko) 2017-04-07
TWI516601B (zh) 2016-01-11
KR20160042162A (ko) 2016-04-18
JP2016048248A (ja) 2016-04-07
AU2008315677B2 (en) 2014-04-17
CA2704126A1 (en) 2009-04-30
CN102232185A (zh) 2011-11-02
EP2210085A4 (en) 2010-12-22
US20100252452A1 (en) 2010-10-07
KR20100087181A (ko) 2010-08-03
PL2210085T3 (pl) 2016-05-31

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