MX357692B - Analisis genomico a base de tamaño. - Google Patents
Analisis genomico a base de tamaño.Info
- Publication number
- MX357692B MX357692B MX2015002302A MX2015002302A MX357692B MX 357692 B MX357692 B MX 357692B MX 2015002302 A MX2015002302 A MX 2015002302A MX 2015002302 A MX2015002302 A MX 2015002302A MX 357692 B MX357692 B MX 357692B
- Authority
- MX
- Mexico
- Prior art keywords
- size
- chromosome
- haplotype
- size distribution
- fetus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/10—Ploidy or copy number detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25907609P | 2009-11-06 | 2009-11-06 | |
| US36039910P | 2010-06-30 | 2010-06-30 | |
| PCT/EP2010/066935 WO2011054936A1 (en) | 2009-11-06 | 2010-11-05 | Size-based genomic analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX357692B true MX357692B (es) | 2018-07-19 |
Family
ID=43530526
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015002302A MX357692B (es) | 2009-11-06 | 2010-11-05 | Analisis genomico a base de tamaño. |
| MX2012005217A MX2012005217A (es) | 2009-11-06 | 2010-11-05 | Analisis genomico a base de tamaño. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012005217A MX2012005217A (es) | 2009-11-06 | 2010-11-05 | Analisis genomico a base de tamaño. |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US8620593B2 (https=) |
| EP (3) | EP2496713B1 (https=) |
| JP (2) | JP5770737B2 (https=) |
| CN (2) | CN102791881B (https=) |
| AU (1) | AU2010317019B2 (https=) |
| CA (1) | CA2780016C (https=) |
| EA (1) | EA034241B1 (https=) |
| ES (1) | ES3026544T3 (https=) |
| IL (1) | IL219545A (https=) |
| MX (2) | MX357692B (https=) |
| TW (1) | TWI445854B (https=) |
| WO (1) | WO2011054936A1 (https=) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2557517T (lt) * | 2007-07-23 | 2023-01-10 | The Chinese University Of Hong Kong | Nukleino rūgščių sekos disbalanso nustatymas |
| CA2717320A1 (en) | 2008-03-11 | 2009-09-17 | Sequenom, Inc. | Nucleic acid-based tests for prenatal gender determination |
| US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| US8962247B2 (en) | 2008-09-16 | 2015-02-24 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses |
| LT3783110T (lt) | 2009-11-05 | 2023-01-25 | The Chinese University Of Hong Kong | Vaisiaus genomo analizė iš motinos biologinio mėginio |
| EA034241B1 (ru) * | 2009-11-06 | 2020-01-21 | Те Чайниз Юниверсити Ов Гонконг | Способ пренатальной диагностики дисбаланса последовательности |
| EP3088532B1 (en) | 2009-12-22 | 2019-10-30 | Sequenom, Inc. | Processes and kits for identifying aneuploidy |
| CN101921874B (zh) * | 2010-06-30 | 2013-09-11 | 深圳华大基因科技有限公司 | 基于Solexa测序法的检测人类乳头瘤病毒的方法 |
| US10167508B2 (en) | 2010-08-06 | 2019-01-01 | Ariosa Diagnostics, Inc. | Detection of genetic abnormalities |
| US11203786B2 (en) | 2010-08-06 | 2021-12-21 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
| US20140342940A1 (en) | 2011-01-25 | 2014-11-20 | Ariosa Diagnostics, Inc. | Detection of Target Nucleic Acids using Hybridization |
| US20130040375A1 (en) | 2011-08-08 | 2013-02-14 | Tandem Diagnotics, Inc. | Assay systems for genetic analysis |
| US11031095B2 (en) | 2010-08-06 | 2021-06-08 | Ariosa Diagnostics, Inc. | Assay systems for determination of fetal copy number variation |
| US8700338B2 (en) | 2011-01-25 | 2014-04-15 | Ariosa Diagnosis, Inc. | Risk calculation for evaluation of fetal aneuploidy |
| US20130261003A1 (en) | 2010-08-06 | 2013-10-03 | Ariosa Diagnostics, In. | Ligation-based detection of genetic variants |
| US10533223B2 (en) | 2010-08-06 | 2020-01-14 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
| US20120034603A1 (en) | 2010-08-06 | 2012-02-09 | Tandem Diagnostics, Inc. | Ligation-based detection of genetic variants |
| MX349568B (es) | 2010-11-30 | 2017-08-03 | Univ Hong Kong Chinese | Deteccion de aberraciones geneticas o moleculares asociadas con el cancer. |
| US11270781B2 (en) | 2011-01-25 | 2022-03-08 | Ariosa Diagnostics, Inc. | Statistical analysis for non-invasive sex chromosome aneuploidy determination |
| US9994897B2 (en) | 2013-03-08 | 2018-06-12 | Ariosa Diagnostics, Inc. | Non-invasive fetal sex determination |
| US10131947B2 (en) | 2011-01-25 | 2018-11-20 | Ariosa Diagnostics, Inc. | Noninvasive detection of fetal aneuploidy in egg donor pregnancies |
| US8756020B2 (en) | 2011-01-25 | 2014-06-17 | Ariosa Diagnostics, Inc. | Enhanced risk probabilities using biomolecule estimations |
| WO2012149339A2 (en) | 2011-04-29 | 2012-11-01 | Sequenom, Inc. | Quantification of a minority nucleic acid species |
| US8712697B2 (en) | 2011-09-07 | 2014-04-29 | Ariosa Diagnostics, Inc. | Determination of copy number variations using binomial probability calculations |
| US10424394B2 (en) | 2011-10-06 | 2019-09-24 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| WO2013060762A1 (en) * | 2011-10-25 | 2013-05-02 | Roche Diagnostics Gmbh | Method for diagnosing a disease based on plasma-dna distribution |
| HK1206055A1 (en) | 2012-03-02 | 2015-12-31 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US9892230B2 (en) * | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
| JP6411995B2 (ja) * | 2012-03-13 | 2018-10-24 | ザ チャイニーズ ユニバーシティー オブ ホンコン | 非侵襲的出生前診断のために大量並列シークエンシング・データを分析する方法 |
| US10289800B2 (en) | 2012-05-21 | 2019-05-14 | Ariosa Diagnostics, Inc. | Processes for calculating phased fetal genomic sequences |
| US9920361B2 (en) | 2012-05-21 | 2018-03-20 | Sequenom, Inc. | Methods and compositions for analyzing nucleic acid |
| US10504613B2 (en) | 2012-12-20 | 2019-12-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US11261494B2 (en) | 2012-06-21 | 2022-03-01 | The Chinese University Of Hong Kong | Method of measuring a fractional concentration of tumor DNA |
| US20140093873A1 (en) | 2012-07-13 | 2014-04-03 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| JP2015522293A (ja) | 2012-07-19 | 2015-08-06 | アリオサ ダイアグノスティックス インコーポレイテッドＡｒｉｏｓａ Ｄｉａｇｎｏｓｔｉｃｓ，Ｉｎｃ． | 多重化連続ライゲーションに基づく遺伝子変異体の検出 |
| GB201215449D0 (en) * | 2012-08-30 | 2012-10-17 | Zoragen Biotechnologies Llp | Method of detecting chromosonal abnormalities |
| BR122021021823B1 (pt) | 2012-09-20 | 2023-04-25 | The Chinese University Of Hong Kong | Método para determinar um primeiro perfil de metilação de uma amostra biológica de um organismo, e, meio de armazenamento de memória |
| US10482994B2 (en) | 2012-10-04 | 2019-11-19 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| HK1216655A1 (zh) | 2013-03-13 | 2016-11-25 | Sequenom, Inc. | 用於dna甲基化分析的引物 |
| TWI637058B (zh) | 2013-03-15 | 2018-10-01 | 香港中文大學 | 測定多胞胎妊娠之胎兒基因組 |
| CN112037860B (zh) * | 2013-06-13 | 2024-02-23 | 豪夫迈·罗氏有限公司 | 用于非入侵性性染色体非整倍性确定的统计分析 |
| HUE042654T2 (hu) * | 2013-06-21 | 2019-07-29 | Sequenom Inc | Eljárás genetikai variációk nem-invazív megállapítására |
| KR102429186B1 (ko) | 2013-10-21 | 2022-08-03 | 베리나타 헬스, 인코포레이티드 | 사본수 변동을 결정함에 있어서 검출의 감수성을 향상시키기 위한 방법 |
| US11365447B2 (en) | 2014-03-13 | 2022-06-21 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| CA2950596C (en) | 2014-05-30 | 2023-10-31 | Verinata Health, Inc. | Detecting fetal sub-chromosomal aneuploidies and copy number variations |
| AU2015269103B2 (en) | 2014-06-06 | 2021-12-23 | Cornell University | Method for identification and enumeration of nucleic acid sequence, expression, copy, or DNA methylation changes, using combined nuclease, ligase, polymerase, and sequencing reactions |
| ES2741400T3 (es) | 2014-07-18 | 2020-02-10 | Univ Hong Kong Chinese | Análisis de patrones de metilación de tejidos en mezcla de ADN |
| CN107002122B (zh) | 2014-07-25 | 2023-09-19 | 华盛顿大学 | 确定导致无细胞dna的产生的组织和/或细胞类型的方法以及使用其鉴定疾病或紊乱的方法 |
| EP3175236B1 (en) * | 2014-08-01 | 2019-08-21 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
| EP3502273B1 (en) | 2014-12-12 | 2020-07-08 | Verinata Health, Inc. | Cell-free dna fragment |
| US11242559B2 (en) | 2015-01-13 | 2022-02-08 | The Chinese University Of Hong Kong | Method of nuclear DNA and mitochondrial DNA analysis |
| US10364467B2 (en) | 2015-01-13 | 2019-07-30 | The Chinese University Of Hong Kong | Using size and number aberrations in plasma DNA for detecting cancer |
| US10319463B2 (en) * | 2015-01-23 | 2019-06-11 | The Chinese University Of Hong Kong | Combined size- and count-based analysis of maternal plasma for detection of fetal subchromosomal aberrations |
| EP3256605B1 (en) | 2015-02-10 | 2022-02-09 | The Chinese University Of Hong Kong | Detecting mutations for cancer screening and fetal analysis |
| CN104789686B (zh) * | 2015-05-06 | 2018-09-07 | 浙江安诺优达生物科技有限公司 | 检测染色体非整倍性的试剂盒和装置 |
| PL3666902T3 (pl) | 2015-05-22 | 2025-02-03 | Medicover Public Co Ltd | Multipleksowa równoległa analiza docelowych regionów genomowych do nieinwazyjnych badań prenatalnych |
| EP4063517B1 (en) | 2015-07-20 | 2026-01-07 | The Chinese University Of Hong Kong | Methylation pattern analysis of haplotypes in cell-free dna mixtures of maternal and fetal dna |
| IL305462A (en) | 2015-07-23 | 2023-10-01 | Univ Hong Kong Chinese | DNA fragmentation pattern analysis suitable clean |
| CA2995422A1 (en) | 2015-08-12 | 2017-02-16 | The Chinese University Of Hong Kong | Single-molecule sequencing of plasma dna |
| US10095831B2 (en) | 2016-02-03 | 2018-10-09 | Verinata Health, Inc. | Using cell-free DNA fragment size to determine copy number variations |
| KR20190017738A (ko) * | 2016-04-11 | 2019-02-20 | 퀀텀 바이오시스템즈 가부시키가이샤 | 생물학적 데이터 관리를 위한 시스템 및 방법 |
| EP3518974A4 (en) | 2016-09-29 | 2020-05-27 | Myriad Women's Health, Inc. | NON-INVASIVE PRENATAL SCREENING USING DYNAMIC ITERATIVE DEEP OPTIMIZATION |
| EP4209598A1 (en) | 2016-10-19 | 2023-07-12 | The Chinese University of Hong Kong | Gestational age assessment by methylation and size profiling of maternal plasma dna |
| TWI797095B (zh) | 2016-10-24 | 2023-04-01 | 美商格瑞爾有限責任公司 | 腫瘤檢測之方法及系統 |
| CN106591451B (zh) * | 2016-12-14 | 2020-06-23 | 北京贝瑞和康生物技术有限公司 | 测定胎儿游离dna含量的方法及其用于实施该方法的装置 |
| EP4421489B1 (en) | 2017-01-25 | 2026-03-11 | The Chinese University of Hong Kong | Diagnostic applications using nucleic acid fragments |
| JP7370862B2 (ja) | 2017-03-17 | 2023-10-30 | セクエノム， インコーポレイテッド | 遺伝子モザイク症のための方法およびプロセス |
| CN110914456A (zh) * | 2017-03-31 | 2020-03-24 | 普莱梅沙有限公司 | 检测胎儿染色体异常的方法 |
| US11342047B2 (en) | 2017-04-21 | 2022-05-24 | Illumina, Inc. | Using cell-free DNA fragment size to detect tumor-associated variant |
| IL316163A (en) | 2017-07-26 | 2024-12-01 | Univ Hong Kong Chinese | Enhancement of cancer screening using cell-free viral nucleic acids |
| US11168356B2 (en) | 2017-11-02 | 2021-11-09 | The Chinese University Of Hong Kong | Using nucleic acid size range for noninvasive cancer detection |
| CN108827887B (zh) * | 2018-03-19 | 2021-05-18 | 陕西学前师范学院 | 一种商陆基因组大小估计方法及基因组大小测量系统 |
| KR20210014111A (ko) | 2018-05-03 | 2021-02-08 | 더 차이니즈 유니버시티 오브 홍콩 | 세포-무함유 혼합물의 특성을 측정하기 위한 크기-태깅된 바람직한 말단 및 배향-인지 분석 |
| WO2020192680A1 (en) | 2019-03-25 | 2020-10-01 | The Chinese University Of Hong Kong | Determining linear and circular forms of circulating nucleic acids |
| CA3147613A1 (en) * | 2019-08-19 | 2021-02-25 | Chang-Seok Ki | Method for detecting chromosomal abnormality by using information about distance between nucleic acid fragments |
| BR112022015073A2 (pt) | 2020-02-05 | 2022-11-16 | Univ Hong Kong Chinese | Método de análise de uma amostra biológica, produto de programa de computador, mídia de armazenamento, e, sistema de computação |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0016742D0 (en) * | 2000-07-10 | 2000-08-30 | Simeg Limited | Diagnostic method |
| US6664056B2 (en) * | 2000-10-17 | 2003-12-16 | The Chinese University Of Hong Kong | Non-invasive prenatal monitoring |
| EP1370692A2 (fr) * | 2001-03-23 | 2003-12-17 | Gencell S.A. | Procedes de purification et de detection de sequences cibles d'adn double brin par interaction triple helice. |
| US6927028B2 (en) | 2001-08-31 | 2005-08-09 | Chinese University Of Hong Kong | Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA |
| WO2004078999A1 (en) | 2003-03-05 | 2004-09-16 | Genetic Technologies Limited | Identification of fetal dna and fetal cell markers in maternal plasma or serum |
| AU2003901671A0 (en) * | 2003-04-02 | 2003-05-01 | The University Of Adelaide | Comparative genomic hybridization |
| DE60328193D1 (de) * | 2003-10-16 | 2009-08-13 | Sequenom Inc | Nicht invasiver Nachweis fötaler genetischer Merkmale |
| CA2601221C (en) * | 2005-03-18 | 2013-08-06 | The Chinese University Of Hong Kong | A method for the detection of chromosomal aneuploidies |
| US20070122823A1 (en) * | 2005-09-01 | 2007-05-31 | Bianchi Diana W | Amniotic fluid cell-free fetal DNA fragment size pattern for prenatal diagnosis |
| TR201910868T4 (tr) | 2006-02-02 | 2019-08-21 | Univ Leland Stanford Junior | Dijital analizle invazif olmayan fetal genetik tarama. |
| EP2351858B1 (en) | 2006-02-28 | 2014-12-31 | University of Louisville Research Foundation | Detecting fetal chromosomal abnormalities using tandem single nucleotide polymorphisms |
| ES2391212T3 (es) * | 2006-12-07 | 2012-11-22 | Novartis Ag | Cribado genético prenatal no-invasivo |
| US12180549B2 (en) * | 2007-07-23 | 2024-12-31 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using genomic sequencing |
| LT2557517T (lt) | 2007-07-23 | 2023-01-10 | The Chinese University Of Hong Kong | Nukleino rūgščių sekos disbalanso nustatymas |
| US20090053719A1 (en) | 2007-08-03 | 2009-02-26 | The Chinese University Of Hong Kong | Analysis of nucleic acids by digital pcr |
| WO2010053980A2 (en) | 2008-11-04 | 2010-05-14 | The Johns Hopkins University | Dna integrity assay (dia) for cancer diagnostics, using confocal fluorescence spectroscopy |
| SG174401A1 (en) | 2009-03-31 | 2011-11-28 | Oridis Biomarkers Gmbh | Method for diagnosis of cancer and monitoring of cancer treatments |
| WO2011053790A2 (en) | 2009-10-30 | 2011-05-05 | Fluidigm Corporation | Assay of closely linked targets in fetal diagnosis and coincidence detection assay for genetic analysis |
| EA034241B1 (ru) * | 2009-11-06 | 2020-01-21 | Те Чайниз Юниверсити Ов Гонконг | Способ пренатальной диагностики дисбаланса последовательности |
| ES2534758T3 (es) | 2010-01-19 | 2015-04-28 | Verinata Health, Inc. | Métodos de secuenciación en diagnósticos prenatales |
| CA2786564A1 (en) | 2010-01-19 | 2011-07-28 | Verinata Health, Inc. | Identification of polymorphic sequences in mixtures of genomic dna by whole genome sequencing |
| WO2011103236A2 (en) | 2010-02-18 | 2011-08-25 | The Johns Hopkins University | Personalized tumor biomarkers |
| US9892230B2 (en) | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
-
2010
- 2010-11-05 EA EA201200701A patent/EA034241B1/ru unknown
- 2010-11-05 MX MX2015002302A patent/MX357692B/es unknown
- 2010-11-05 MX MX2012005217A patent/MX2012005217A/es active IP Right Grant
- 2010-11-05 ES ES23160186T patent/ES3026544T3/es active Active
- 2010-11-05 WO PCT/EP2010/066935 patent/WO2011054936A1/en not_active Ceased
- 2010-11-05 TW TW099138272A patent/TWI445854B/zh active
- 2010-11-05 EP EP10779290.5A patent/EP2496713B1/en active Active
- 2010-11-05 CN CN201080059269.7A patent/CN102791881B/zh active Active
- 2010-11-05 US US12/940,992 patent/US8620593B2/en active Active
- 2010-11-05 EP EP18182983.9A patent/EP3406737B1/en active Active
- 2010-11-05 CN CN201710549501.9A patent/CN107312844B/zh active Active
- 2010-11-05 EP EP23160186.5A patent/EP4212630B1/en active Active
- 2010-11-05 AU AU2010317019A patent/AU2010317019B2/en active Active
- 2010-11-05 JP JP2012537410A patent/JP5770737B2/ja active Active
- 2010-11-05 CA CA2780016A patent/CA2780016C/en active Active
-
2012
- 2012-05-02 IL IL219545A patent/IL219545A/en active IP Right Grant
-
2013
- 2013-11-25 US US14/089,720 patent/US9982300B2/en active Active
-
2015
- 2015-04-27 JP JP2015090264A patent/JP6001721B2/ja active Active
-
2018
- 2018-04-20 US US15/958,376 patent/US11365448B2/en active Active
-
2022
- 2022-05-12 US US17/742,749 patent/US20220282332A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW201129736A (en) | Size-based genomic analysis | |
| CA3010254C (en) | Size-based analysis of fetal dna fraction in maternal plasma | |
| Mantikou et al. | Molecular origin of mitotic aneuploidies in preimplantation embryos | |
| Ryan et al. | Informatics-based, highly accurate, noninvasive prenatal paternity testing | |
| WO2009114543A3 (en) | Nucleic acid-based tests for prenatal gender determination | |
| TWI641834B (zh) | 藉由大量平行ｒｎａ定序之母體血漿轉錄體分析 | |
| MX341573B (es) | Diagnostico de aneuploide cromosomico fetal mediante el uso de secuenciacion genomica. | |
| NZ601079A (en) | Methods and compositions for noninvasive prenatal diagnosis of fetal aneuploidies | |
| GB2484764B (en) | Normalizing chromosomes for the determination and verification of common and rare chromosomal aneuploidies | |
| WO2012088456A3 (en) | Methods for non-invasive prenatal paternity testing | |
| MA39951A (fr) | Détection de l'adn provenant d'un type spécifique de cellule et méthodes associées | |
| AU2014205038A8 (en) | Noninvasive prenatal molecular karyotyping from maternal plasma | |
| WO2011143659A3 (en) | Nucleic acid isolation methods | |
| WO2013177581A3 (en) | Whole genome sequencing of a human fetus | |
| WO2007147073A3 (en) | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats | |
| EP3922731A3 (en) | Methods and processes for non-invasive assessment of genetic variations | |
| WO2012012703A3 (en) | Identification of differentially represented fetal or maternal genomic regions and uses thereof | |
| WO2017009372A3 (en) | System and methodology for the analysis of genomic data obtained from a subject | |
| EA038117B1 (ru) | Мультиплексный параллельный анализ целевых геномных областей с целью неинвазивного пренатального тестирования | |
| MY193127A (en) | Method, device and kit for detecting fetal genetic mutation | |
| CN112888783A (zh) | 改善游离dna质量 | |
| Kim | Advantages of the single nucleotide polymorphism-based noninvasive prenatal test | |
| EA201992444A2 (ru) | Геномный анализ на основе размеров | |
| Ravichandran et al. | Causes and estimated incidences of sex-chromosome misdiagnosis in preimplantation genetic diagnosis of aneuploidy | |
| UA59264U (ru) | Способ прогнозирования индивидуальной склонности к развитию преэклампсии у беременных |