MX354725B - Metodo de tratamiento de una enfermedad proliferativa. - Google Patents
Metodo de tratamiento de una enfermedad proliferativa.Info
- Publication number
- MX354725B MX354725B MX2014005726A MX2014005726A MX354725B MX 354725 B MX354725 B MX 354725B MX 2014005726 A MX2014005726 A MX 2014005726A MX 2014005726 A MX2014005726 A MX 2014005726A MX 354725 B MX354725 B MX 354725B
- Authority
- MX
- Mexico
- Prior art keywords
- treating
- proliferative disease
- serine
- kinase inhibitor
- threonine kinase
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002062 proliferating effect Effects 0.000 title 1
- 229940121742 Serine/threonine kinase inhibitor Drugs 0.000 abstract 3
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161558619P | 2011-11-11 | 2011-11-11 | |
| PCT/US2012/064269 WO2013070996A1 (en) | 2011-11-11 | 2012-11-09 | Method of treating a proliferative disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014005726A MX2014005726A (es) | 2014-05-28 |
| MX354725B true MX354725B (es) | 2018-03-16 |
Family
ID=47279036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014005726A MX354725B (es) | 2011-11-11 | 2012-11-09 | Metodo de tratamiento de una enfermedad proliferativa. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11007194B2 (OSRAM) |
| EP (1) | EP2776037B1 (OSRAM) |
| JP (1) | JP6150813B2 (OSRAM) |
| CN (2) | CN108542906A (OSRAM) |
| AU (1) | AU2012335663B2 (OSRAM) |
| BR (1) | BR112014011223A8 (OSRAM) |
| CA (1) | CA2855243C (OSRAM) |
| MX (1) | MX354725B (OSRAM) |
| RU (1) | RU2622015C2 (OSRAM) |
| WO (1) | WO2013070996A1 (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR077975A1 (es) | 2009-08-28 | 2011-10-05 | Irm Llc | Derivados de pirazol pirimidina y composiciones como inhibidores de cinasa de proteina |
| AU2013299841B8 (en) * | 2012-08-07 | 2017-01-05 | Array Biopharma Inc. | Pharmaceutical combinations comprising a B-Raf inhibitor, an EGFR inhibitor and optionally a PI3K-alpha inhibitor |
| WO2017210538A1 (en) * | 2016-06-03 | 2017-12-07 | Giordano Caponigro | Pharmaceutical combinations |
| WO2018107146A1 (en) * | 2016-12-11 | 2018-06-14 | Memorial Sloan Kettering Cancer Center | Methods and compositions for treatment of braf mutant cancers |
| CN110256408B (zh) * | 2018-07-12 | 2022-03-22 | 深圳市塔吉瑞生物医药有限公司 | 一种二芳基吡唑化合物及包含该化合物的组合物及其用途 |
| TWI817018B (zh) | 2019-06-28 | 2023-10-01 | 美商艾瑞生藥股份有限公司 | 用於治療braf相關的疾病和失調症之化合物 |
| CA3163703A1 (en) * | 2020-01-07 | 2021-07-15 | Steve Kelsey | Shp2 inhibitor dosing and methods of treating cancer |
| JP7312335B2 (ja) | 2020-06-09 | 2023-07-20 | アレイ バイオファーマ インコーポレイテッド | Braf関連疾患および障害を処置するための4-オキソ-3,4-ジヒドロキナゾリノン化合物 |
| CA3257280A1 (en) | 2022-05-25 | 2023-11-30 | Msd International Gmbh | COMBINATION OF A BRAF INHIBITOR, AN EGFR INHIBITOR AND A PD-1 ANTAGONIST FOR THE TREATMENT OF COLORECTAL CANCER MSI-H/DMMR, WITH BRAF V600E MUTATION |
| ES3035530T3 (en) | 2023-03-09 | 2025-09-04 | Minneamrita Therapeutics Llc | Drug combination for the treatment of stomach cancer |
| WO2025003956A1 (en) | 2023-06-30 | 2025-01-02 | Pfizer Inc. | High drug loading formulations of encorafenib |
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| BRPI0818340A2 (pt) | 2007-10-19 | 2015-04-22 | Abbott Gmbh & Co Kg | Produto de dispersão sólida de fármacos baseados em n-aril uréia |
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| HRP20120577T1 (hr) | 2008-07-24 | 2012-08-31 | Nerviano Medical Sciences S.R.L. | 3,4-diarilpirazoli kao inhibitori proteinskih kinaza |
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| AR077975A1 (es) | 2009-08-28 | 2011-10-05 | Irm Llc | Derivados de pirazol pirimidina y composiciones como inhibidores de cinasa de proteina |
| BR112012017705B1 (pt) | 2010-01-27 | 2020-03-24 | Nerviano Medical Science S.R.L. | Derivados de sulfonamidas de 3,4-diarilpirazóis como inibidores da proteína cinase |
| RU2639876C2 (ru) | 2010-03-30 | 2017-12-25 | Версеон Корпорейшн | Мультизамещенные ароматические соединения в качестве ингибиторов тромбина |
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| CN103442715A (zh) | 2011-03-21 | 2013-12-11 | 瓦尔库里亚公司 | 包括hdac抑制剂以及类固醇的药用组合物及其用途 |
| SG195141A1 (en) | 2011-06-14 | 2013-12-30 | Novartis Ag | Combination of panobinostat and ruxolitinib in the treatment of cancer suchas a myeloproliferative neoplasm |
| PE20141994A1 (es) | 2011-11-23 | 2014-12-24 | Novartis Ag | Formulaciones farmaceuticas |
| AU2013343425A1 (en) | 2012-11-08 | 2015-06-11 | Novartis Ag | Pharmaceutical combination comprising a B-Raf inhibitor and a histone deacetylase inhibitor and their use in the treatment of proliferative diseases |
-
2012
- 2012-11-09 CA CA2855243A patent/CA2855243C/en active Active
- 2012-11-09 US US14/355,903 patent/US11007194B2/en active Active
- 2012-11-09 CN CN201810135736.8A patent/CN108542906A/zh active Pending
- 2012-11-09 WO PCT/US2012/064269 patent/WO2013070996A1/en not_active Ceased
- 2012-11-09 AU AU2012335663A patent/AU2012335663B2/en active Active
- 2012-11-09 BR BR112014011223A patent/BR112014011223A8/pt not_active Application Discontinuation
- 2012-11-09 RU RU2014117707A patent/RU2622015C2/ru active
- 2012-11-09 MX MX2014005726A patent/MX354725B/es active IP Right Grant
- 2012-11-09 JP JP2014541283A patent/JP6150813B2/ja active Active
- 2012-11-09 CN CN201280054663.0A patent/CN103917236A/zh active Pending
- 2012-11-09 EP EP12795175.4A patent/EP2776037B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012335663A1 (en) | 2014-05-29 |
| BR112014011223A2 (pt) | 2017-05-09 |
| JP6150813B2 (ja) | 2017-06-21 |
| JP2014533272A (ja) | 2014-12-11 |
| US20140275136A1 (en) | 2014-09-18 |
| RU2014117707A (ru) | 2015-12-20 |
| MX2014005726A (es) | 2014-05-28 |
| EP2776037B1 (en) | 2019-01-09 |
| CN108542906A (zh) | 2018-09-18 |
| EP2776037A1 (en) | 2014-09-17 |
| BR112014011223A8 (pt) | 2023-01-31 |
| WO2013070996A1 (en) | 2013-05-16 |
| AU2012335663B2 (en) | 2015-12-24 |
| CA2855243C (en) | 2020-04-14 |
| CA2855243A1 (en) | 2013-05-16 |
| HK1198920A1 (en) | 2015-06-19 |
| US11007194B2 (en) | 2021-05-18 |
| RU2622015C2 (ru) | 2017-06-08 |
| CN103917236A (zh) | 2014-07-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |