MX354156B - Dipeptido que comprende un aminoacido no proteogenico. - Google Patents

Dipeptido que comprende un aminoacido no proteogenico.

Info

Publication number
MX354156B
MX354156B MX2014007604A MX2014007604A MX354156B MX 354156 B MX354156 B MX 354156B MX 2014007604 A MX2014007604 A MX 2014007604A MX 2014007604 A MX2014007604 A MX 2014007604A MX 354156 B MX354156 B MX 354156B
Authority
MX
Mexico
Prior art keywords
dipeptide
amino acid
proteogenic amino
proteogenic
making
Prior art date
Application number
MX2014007604A
Other languages
English (en)
Other versions
MX2014007604A (es
Inventor
Christensen Caspar
Raunkjaer Michael
Severinsen Rune
Christian Norrild Jens
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of MX2014007604A publication Critical patent/MX2014007604A/es
Publication of MX354156B publication Critical patent/MX354156B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K4/00—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06147—Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a un dipéptido que comprende un aminoácido no proteogénico, métodos para hacer tal y métodos para usar el dipéptido en un proceso para hacer un polipéptido o proteína que comprenda uno o más aminoácidos no proteogénicos.
MX2014007604A 2011-12-29 2012-12-20 Dipeptido que comprende un aminoacido no proteogenico. MX354156B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11195998 2011-12-29
US201261593524P 2012-02-01 2012-02-01
PCT/EP2012/076408 WO2013098191A1 (en) 2011-12-29 2012-12-20 Dipeptide comprising a non-proteogenic amino acid

Publications (2)

Publication Number Publication Date
MX2014007604A MX2014007604A (es) 2014-09-15
MX354156B true MX354156B (es) 2018-02-15

Family

ID=48696363

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014007604A MX354156B (es) 2011-12-29 2012-12-20 Dipeptido que comprende un aminoacido no proteogenico.

Country Status (11)

Country Link
US (3) US20140364587A1 (es)
EP (1) EP2797947B1 (es)
JP (1) JP6046161B2 (es)
KR (1) KR101922164B1 (es)
CN (2) CN104011064A (es)
AU (1) AU2012360998B2 (es)
CA (1) CA2861000A1 (es)
ES (1) ES2682253T3 (es)
MX (1) MX354156B (es)
RU (1) RU2643515C2 (es)
WO (1) WO2013098191A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106928340A (zh) * 2015-12-31 2017-07-07 深圳翰宇药业股份有限公司 一种利西拉来的制备方法
ES2835033T3 (es) 2016-03-03 2021-06-21 Novo Nordisk As Derivados de GLP-1 y sus usos
PT3426348T (pt) 2016-03-11 2021-06-28 Intercept Pharmaceuticals Inc Derivado de 3-desoxi e composições farmacêuticas do mesmo
MA46780A (fr) 2016-11-07 2019-09-11 Novo Nordisk As Esters à dchbs actif de composés peg et leur utilisation
EP3655427A1 (en) 2017-07-19 2020-05-27 Novo Nordisk A/S Bifunctional compounds
WO2020190757A1 (en) 2019-03-15 2020-09-24 Novetide Ltd. Improved processes for the preparation of semaglutide
US20240124520A1 (en) * 2019-10-16 2024-04-18 The Board Of Trustees Of The Leland Stanford Junior University N-acylated histidine dipeptides as anticancer agents
KR102647938B1 (ko) * 2020-09-14 2024-03-15 엘지전자 주식회사 이차전지의 파우치 두께 측정장치
WO2023012829A1 (en) * 2021-08-04 2023-02-09 Msn Laboratories Private Limited, R&D Center Process for the preparation of semaglutide
WO2026013265A1 (en) 2024-07-12 2026-01-15 Novo Nordisk A/S Novel dipeptide acylating agents

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705483A (en) 1993-12-09 1998-01-06 Eli Lilly And Company Glucagon-like insulinotropic peptides, compositions and methods
US6277819B1 (en) 1996-08-30 2001-08-21 Eli Lilly And Company Use of GLP-1 or analogs in treatment of myocardial infarction
US6458924B2 (en) 1996-08-30 2002-10-01 Novo Nordisk A/S Derivatives of GLP-1 analogs
IL128332A0 (en) 1996-08-30 2000-01-31 Novo Nordisk As GLP-1 derivatives
CA2283834A1 (en) 1997-03-31 1998-10-08 James Arthur Hoffmann Glucagon-like peptide-1 analogs
CN1352034A (zh) * 2000-11-10 2002-06-05 上海博德基因开发有限公司 一种新的多肽——二肽氨基肽酶iv相关蛋白(dppx)9.24和编码这种多肽的多核苷酸
US7595172B2 (en) 2001-07-24 2009-09-29 Novo Nordisk A/S Method for making acylated polypeptides
CA2539253A1 (en) 2003-09-19 2005-03-31 Novo Nordisk A/S Albumin-binding derivatives of therapeutic peptides
BRPI0417684A (pt) 2003-12-18 2007-03-20 Novo Nordisk As composto, composição farmacêutica, e, uso de um composto
ES2542228T3 (es) 2004-07-08 2015-08-03 Novo Nordisk A/S Marcas de prolongación polipeptídica que comprenden un resto de tetrazol
WO2006037810A2 (en) 2004-10-07 2006-04-13 Novo Nordisk A/S Protracted glp-1 compounds
TWI372629B (en) 2005-03-18 2012-09-21 Novo Nordisk As Acylated glp-1 compounds
BRPI0608516A2 (pt) 2005-03-18 2010-11-16 Novo Nordisk As análogo de glp-1, método para aumentar o tempo de ação em um paciente de um análogo de glp-1, composição farmacêutica, e, uso de um composto
EP1863537A2 (en) 2005-03-18 2007-12-12 Novo Nordisk A/S Dimeric peptide agonists of the glp-1 receptor
CN101151369B (zh) * 2005-03-29 2017-02-15 协和发酵生化株式会社 二肽的结晶及其制备方法
NZ573093A (en) * 2006-06-23 2012-01-12 Hoffmann La Roche Insulinotropic peptide synthesis
US20100317057A1 (en) * 2007-12-28 2010-12-16 Novo Nordisk A/S Semi-recombinant preparation of glp-1 analogues
WO2009147816A1 (ja) 2008-06-02 2009-12-10 国立大学法人鳥取大学 ヘテロポリ酸分解触媒及びそれを用いるディーゼル燃料油の製造方法
CN102414220A (zh) * 2009-05-01 2012-04-11 霍夫曼-拉罗奇有限公司 使用固相和液相组合技术的促胰岛素肽合成
CN104327182B (zh) 2009-12-16 2020-04-17 诺沃—诺迪斯克有限公司 双酰化glp-1衍生物

Also Published As

Publication number Publication date
JP6046161B2 (ja) 2016-12-14
US10954267B2 (en) 2021-03-23
US20190002496A1 (en) 2019-01-03
WO2013098191A1 (en) 2013-07-04
BR112014015947A2 (pt) 2021-05-25
AU2012360998A1 (en) 2014-06-19
CA2861000A1 (en) 2013-07-04
EP2797947B1 (en) 2018-05-02
EP2797947A1 (en) 2014-11-05
RU2643515C2 (ru) 2018-02-02
CN110041399B (zh) 2023-12-12
MX2014007604A (es) 2014-09-15
AU2012360998B2 (en) 2017-11-23
RU2014130446A (ru) 2016-02-20
CN104011064A (zh) 2014-08-27
KR20140111651A (ko) 2014-09-19
KR101922164B1 (ko) 2019-02-13
ES2682253T3 (es) 2018-09-19
JP2015503534A (ja) 2015-02-02
CN110041399A (zh) 2019-07-23
BR112014015947A8 (pt) 2017-07-04
US20170096450A1 (en) 2017-04-06
US20140364587A1 (en) 2014-12-11

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