MX352827B - Valoracion de la actividad de la ruta de señalizacion celular usando modelado probabilistico de la expresion del gen diana. - Google Patents

Valoracion de la actividad de la ruta de señalizacion celular usando modelado probabilistico de la expresion del gen diana.

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Publication number
MX352827B
MX352827B MX2014000557A MX2014000557A MX352827B MX 352827 B MX352827 B MX 352827B MX 2014000557 A MX2014000557 A MX 2014000557A MX 2014000557 A MX2014000557 A MX 2014000557A MX 352827 B MX352827 B MX 352827B
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Mexico
Prior art keywords
signaling pathway
cellular signaling
target gene
assessment
gene expression
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MX2014000557A
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English (en)
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MX2014000557A (es
Inventor
Hoffmann Ralf
Jan Van Ooijen Hendrik
Franciscus Johannes Verhaegh Wilhelmus
Van De Stolpe Anja
Chakravarthi Dulla Kalyana
Alves De Inda Marcia
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Koninklijke Philips Nv
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Publication of MX2014000557A publication Critical patent/MX2014000557A/es
Publication of MX352827B publication Critical patent/MX352827B/es

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Abstract

La presente invención se refiere principalmente a métodos específicos para inferir la actividad de una o más rutas de señalización celular en tejido de un sujeto médico en base a al menos los niveles de expresión de uno o más genes diana de las rutas de señalización celular medidos en una muestra extraída del tejido del sujeto médico, un aparato que comprende un procesador digital configurado para realizar estos métodos y un medio de almacenamiento no transitorio que almacena instrucciones que son ejecutables por un dispositivo de procesamiento digital para realizar estos métodos.
MX2014000557A 2011-07-19 2012-07-19 Valoracion de la actividad de la ruta de señalizacion celular usando modelado probabilistico de la expresion del gen diana. MX352827B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161509137P 2011-07-19 2011-07-19
EP11178148A EP2549399A1 (en) 2011-07-19 2011-08-19 Assessment of Wnt pathway activity using probabilistic modeling of target gene expression
PCT/IB2012/053686 WO2013011479A2 (en) 2011-07-19 2012-07-19 Assessment of cellular signaling pathway activity using probabilistic modeling of target gene expression

Publications (2)

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MX2014000557A MX2014000557A (es) 2014-05-01
MX352827B true MX352827B (es) 2017-12-11

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US (2) US11443831B2 (es)
EP (6) EP2549399A1 (es)
JP (3) JP6204354B2 (es)
KR (1) KR102064004B1 (es)
CN (2) CN109852671A (es)
BR (1) BR112014000965B8 (es)
DK (3) DK2734643T3 (es)
ES (3) ES2874452T3 (es)
IN (1) IN2014CN00675A (es)
MX (1) MX352827B (es)
RU (1) RU2719194C2 (es)
WO (1) WO2013011479A2 (es)

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