MX352117B - Anticuerpo anti-idiotipo dirigido contra un anticuerpo dirigido contra el peptido beta amiloideo. - Google Patents

Anticuerpo anti-idiotipo dirigido contra un anticuerpo dirigido contra el peptido beta amiloideo.

Info

Publication number
MX352117B
MX352117B MX2014009062A MX2014009062A MX352117B MX 352117 B MX352117 B MX 352117B MX 2014009062 A MX2014009062 A MX 2014009062A MX 2014009062 A MX2014009062 A MX 2014009062A MX 352117 B MX352117 B MX 352117B
Authority
MX
Mexico
Prior art keywords
antibody against
amyloid
peptide
antibody
idiotype
Prior art date
Application number
MX2014009062A
Other languages
English (en)
Inventor
Stubenrauch Kay-Gunnar
Essig Ulrich
Hoesel Wolfgang
Vogel Rudolf
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX352117B publication Critical patent/MX352117B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/686—Anti-idiotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4709—Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención se refiere a un método para la determinación inmunológica de un anticuerpo contra el péptido amiloide ß en una muestra que utiliza un inmunoensayo empleando un anticuerpo obtenido de la línea de células DSM ACC2939, caracterizado porque le inmunoensayo comprende un anticuerpo de captación, un anticuerpo trazador y un anticuerpo de detección, en donde el anticuerpo de captación es un anticuerpo antí-idiotipo biotinilado contra un anticuerpo contra el péptido amiloido ß obtenido de la línea de célulcas DSM ACC2939 conjugado a una fase sólida vía estreptavidina, el anticuerpo trazador es un anticuerpo anti-idiotipo contra un anticuerpo contra el péptido amiloide ß obtenido de la línea de células DSM ACC 2939 conjugado a digoxigenina como marca detectable, y el anticuerpo de detección es un anticuerpo contra digoxigenina conjugado a una peroxidasa.
MX2014009062A 2008-12-22 2009-12-18 Anticuerpo anti-idiotipo dirigido contra un anticuerpo dirigido contra el peptido beta amiloideo. MX352117B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08022235 2008-12-22
PCT/EP2009/009160 WO2010072384A1 (en) 2008-12-22 2009-12-18 ANTI-IDIOTYPE ANTIBODY AGAINST AN ANTIBODY AGAINST THE AMYLOID β PEPTIDE

Publications (1)

Publication Number Publication Date
MX352117B true MX352117B (es) 2017-11-09

Family

ID=40581970

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2014009062A MX352117B (es) 2008-12-22 2009-12-18 Anticuerpo anti-idiotipo dirigido contra un anticuerpo dirigido contra el peptido beta amiloideo.
MX2011006641A MX2011006641A (es) 2008-12-22 2009-12-18 Anticuerpo anti-idiotipo dirigido contra un anticuerpo dirigido contra el peptido beta amiloideo.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2011006641A MX2011006641A (es) 2008-12-22 2009-12-18 Anticuerpo anti-idiotipo dirigido contra un anticuerpo dirigido contra el peptido beta amiloideo.

Country Status (22)

Country Link
US (2) US8614297B2 (es)
EP (1) EP2379601B1 (es)
JP (1) JP5642702B2 (es)
KR (2) KR20110086182A (es)
CN (2) CN106990251B (es)
AR (1) AR074816A1 (es)
AU (1) AU2009331900A1 (es)
BR (1) BRPI0923544B1 (es)
CA (1) CA2746779C (es)
CY (1) CY1118420T1 (es)
DK (1) DK2379601T3 (es)
ES (1) ES2595981T3 (es)
HR (1) HRP20161398T1 (es)
HU (1) HUE030478T2 (es)
IL (1) IL213343A0 (es)
LT (1) LT2379601T (es)
MX (2) MX352117B (es)
PL (1) PL2379601T3 (es)
PT (1) PT2379601T (es)
SI (1) SI2379601T1 (es)
TW (1) TWI424162B (es)
WO (1) WO2010072384A1 (es)

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US9334319B2 (en) 2012-04-20 2016-05-10 Abbvie Inc. Low acidic species compositions
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
WO2013177115A2 (en) * 2012-05-21 2013-11-28 Abbvie Inc. Novel purification of human, humanized, or chimeric antibodies using protein a affinity chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
CA2905010A1 (en) 2013-03-12 2014-09-18 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
EP3176580A1 (en) 2015-12-01 2017-06-07 Roche Diagnostics GmbH Method for reduction of interferences in immunoassays
EP3508849B1 (en) * 2016-08-31 2023-04-19 Eiken Kagaku Kabushiki Kaisha Antibody measurement method using antigen-carrying insoluble carrier particles on which antigen is immobilized by different methods, and reagent for antibody measurement

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Also Published As

Publication number Publication date
AU2009331900A1 (en) 2010-07-01
CA2746779A1 (en) 2010-07-01
US9547010B2 (en) 2017-01-17
HUE030478T2 (en) 2017-05-29
SI2379601T1 (sl) 2016-11-30
BRPI0923544A2 (pt) 2016-01-26
PT2379601T (pt) 2016-10-04
EP2379601A1 (en) 2011-10-26
KR20130088199A (ko) 2013-08-07
US8614297B2 (en) 2013-12-24
CA2746779C (en) 2017-01-24
ES2595981T3 (es) 2017-01-04
AR074816A1 (es) 2011-02-16
JP2012513426A (ja) 2012-06-14
IL213343A0 (en) 2011-07-31
CN106990251A (zh) 2017-07-28
TW201030335A (en) 2010-08-16
BRPI0923544B1 (pt) 2021-11-23
DK2379601T3 (en) 2016-08-29
HRP20161398T1 (hr) 2016-12-16
LT2379601T (lt) 2016-10-25
CN106990251B (zh) 2019-12-27
US20100167313A1 (en) 2010-07-01
CY1118420T1 (el) 2017-06-28
CN102257010A (zh) 2011-11-23
US20130323762A1 (en) 2013-12-05
KR101777899B1 (ko) 2017-09-13
EP2379601B1 (en) 2016-08-10
WO2010072384A1 (en) 2010-07-01
PL2379601T3 (pl) 2017-02-28
JP5642702B2 (ja) 2014-12-17
KR20110086182A (ko) 2011-07-27
TWI424162B (zh) 2014-01-21
MX2011006641A (es) 2011-07-12

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