LT2379601T - Antiidiotipiniai antikūnai, atpažįstantys antikūną prieš amiloido beta peptidą - Google Patents
Antiidiotipiniai antikūnai, atpažįstantys antikūną prieš amiloido beta peptidąInfo
- Publication number
- LT2379601T LT2379601T LTEP09796629.5T LT09796629T LT2379601T LT 2379601 T LT2379601 T LT 2379601T LT 09796629 T LT09796629 T LT 09796629T LT 2379601 T LT2379601 T LT 2379601T
- Authority
- LT
- Lithuania
- Prior art keywords
- antibody against
- amyloid beta
- beta peptide
- idiotype
- idiotype antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/686—Anti-idiotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08022235 | 2008-12-22 | ||
PCT/EP2009/009160 WO2010072384A1 (en) | 2008-12-22 | 2009-12-18 | ANTI-IDIOTYPE ANTIBODY AGAINST AN ANTIBODY AGAINST THE AMYLOID β PEPTIDE |
Publications (1)
Publication Number | Publication Date |
---|---|
LT2379601T true LT2379601T (lt) | 2016-10-25 |
Family
ID=40581970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP09796629.5T LT2379601T (lt) | 2008-12-22 | 2009-12-18 | Antiidiotipiniai antikūnai, atpažįstantys antikūną prieš amiloido beta peptidą |
Country Status (22)
Country | Link |
---|---|
US (2) | US8614297B2 (lt) |
EP (1) | EP2379601B1 (lt) |
JP (1) | JP5642702B2 (lt) |
KR (2) | KR20110086182A (lt) |
CN (2) | CN102257010A (lt) |
AR (1) | AR074816A1 (lt) |
AU (1) | AU2009331900A1 (lt) |
BR (1) | BRPI0923544B1 (lt) |
CA (1) | CA2746779C (lt) |
CY (1) | CY1118420T1 (lt) |
DK (1) | DK2379601T3 (lt) |
ES (1) | ES2595981T3 (lt) |
HR (1) | HRP20161398T1 (lt) |
HU (1) | HUE030478T2 (lt) |
IL (1) | IL213343A0 (lt) |
LT (1) | LT2379601T (lt) |
MX (2) | MX352117B (lt) |
PL (1) | PL2379601T3 (lt) |
PT (1) | PT2379601T (lt) |
SI (1) | SI2379601T1 (lt) |
TW (1) | TWI424162B (lt) |
WO (1) | WO2010072384A1 (lt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2702077A2 (en) | 2011-04-27 | 2014-03-05 | AbbVie Inc. | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
US9334319B2 (en) | 2012-04-20 | 2016-05-10 | Abbvie Inc. | Low acidic species compositions |
WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
WO2013177115A2 (en) * | 2012-05-21 | 2013-11-28 | Abbvie Inc. | Novel purification of human, humanized, or chimeric antibodies using protein a affinity chromatography |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
SG11201507230PA (en) | 2013-03-12 | 2015-10-29 | Abbvie Inc | Human antibodies that bind human tnf-alpha and methods of preparing the same |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
EP3052640A2 (en) | 2013-10-04 | 2016-08-10 | AbbVie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
WO2015073884A2 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
EP3176580A1 (en) * | 2015-12-01 | 2017-06-07 | Roche Diagnostics GmbH | Method for reduction of interferences in immunoassays |
EP3508849B1 (en) * | 2016-08-31 | 2023-04-19 | Eiken Kagaku Kabushiki Kaisha | Antibody measurement method using antigen-carrying insoluble carrier particles on which antigen is immobilized by different methods, and reagent for antibody measurement |
JP7273195B2 (ja) * | 2019-05-13 | 2023-05-12 | エフ. ホフマン-ラ ロシュ アーゲー | 干渉抑制薬物動態イムノアッセイ |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
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US5219730A (en) | 1982-09-28 | 1993-06-15 | New York University | Idiotype-anti-idiotype immunoassay |
US4828981A (en) | 1983-08-24 | 1989-05-09 | Synbiotics Corporation | Immunoassays for determining Dirofilaria immitis infection using antiidiotype monoclonal antibody reagents |
EP0170302A1 (fr) | 1984-06-27 | 1986-02-05 | l'Association internationale à but scientifique, dite: Institut international de pathologie cellulaire et moléculaire | Procédé de dosage immunologique d'une substance dans un échantillon liquide au moyen d'anticorps anti-idiotypiques |
US5238808A (en) | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
US4666829A (en) | 1985-05-15 | 1987-05-19 | University Of California | Polypeptide marker for Alzheimer's disease and its use for diagnosis |
EP0243471A4 (en) | 1985-10-22 | 1989-07-11 | Cooper Lipotech Inc | SOLID PHASE LIPOSOME IMMUNOANALYSIS SYSTEM. |
IL92164A (en) | 1988-11-03 | 1996-01-19 | Igen Inc | Particle-based electrochemiluminescent test method |
US5068088A (en) | 1988-11-03 | 1991-11-26 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescent measurements |
WO1990006515A1 (en) | 1988-12-09 | 1990-06-14 | Centocor, Inc. | Anti-idiotopic immunometric assay |
IL100866A (en) | 1991-02-06 | 1995-10-31 | Igen Inc | Luminescence test method and device based on magnetic tiny particles, containing many magnets |
WO1994001451A2 (en) | 1992-07-13 | 1994-01-20 | Bionebraska, Inc. | Method for modification of recombinant polypeptides |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
US7179892B2 (en) | 2000-12-06 | 2007-02-20 | Neuralab Limited | Humanized antibodies that recognize beta amyloid peptide |
WO2001062801A2 (en) | 2000-02-24 | 2001-08-30 | Washington University | Humanized antibodies that sequester amyloid beta peptide |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
TWI255272B (en) | 2000-12-06 | 2006-05-21 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
US20040192898A1 (en) | 2001-08-17 | 2004-09-30 | Jia Audrey Yunhua | Anti-abeta antibodies |
AR038568A1 (es) | 2002-02-20 | 2005-01-19 | Hoffmann La Roche | Anticuerpos anti-a beta y su uso |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
US7745569B2 (en) | 2003-04-07 | 2010-06-29 | The Regents Of The University Of California | Amyloid specific binding peptides and detecting abeta peptide |
TWI306458B (en) | 2003-05-30 | 2009-02-21 | Elan Pharma Int Ltd | Humanized antibodies that recognize beta amyloid peptide |
US20070110750A1 (en) | 2003-09-12 | 2007-05-17 | The Regents Of The University Of California | Monoclonal antibodies specific for high molecular weight aggregation intermediates common to amyloids formed from proteins of differing sequence |
EP1680666A4 (en) | 2003-10-27 | 2008-03-26 | Monogram Biosciences Inc | ANTI-THERAPEUTIC HUMAN ANTIBODY DETECTION |
CA2564432A1 (en) | 2004-04-27 | 2005-11-10 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Human anti-amyloid .beta. peptide antibody and fragment of said antibody |
EP1781704A2 (en) | 2004-07-30 | 2007-05-09 | Rinat Neuroscience Corp. | Antibodies directed against amyloid-beta peptide and methods using same |
PE20061152A1 (es) | 2004-12-15 | 2006-10-13 | Neuralab Ltd | Anticuerpos humanizados que reconocen el peptido beta amiloideo |
PE20061323A1 (es) | 2005-04-29 | 2007-02-09 | Rinat Neuroscience Corp | Anticuerpos dirigidos contra el peptido amiloide beta y metodos que utilizan los mismos |
US20090061466A1 (en) | 2006-03-09 | 2009-03-05 | Wolfgang Hoesel | Anti-drug antibody assay |
US20080127359A1 (en) * | 2006-11-06 | 2008-05-29 | Hermann Beck | Method for producing anti-idiotypic antibodies |
EP1917854A1 (en) | 2006-11-06 | 2008-05-07 | F. Hoffmann-La Roche Ag | Method for producing anti idiotypic antibodies |
TWI434855B (zh) * | 2006-11-21 | 2014-04-21 | Hoffmann La Roche | 結合物及其在免疫分析中作為參考標準之用途 |
-
2009
- 2009-12-15 US US12/637,833 patent/US8614297B2/en active Active
- 2009-12-18 JP JP2011542710A patent/JP5642702B2/ja active Active
- 2009-12-18 DK DK09796629.5T patent/DK2379601T3/en active
- 2009-12-18 WO PCT/EP2009/009160 patent/WO2010072384A1/en active Application Filing
- 2009-12-18 CA CA2746779A patent/CA2746779C/en active Active
- 2009-12-18 MX MX2014009062A patent/MX352117B/es unknown
- 2009-12-18 KR KR1020117014278A patent/KR20110086182A/ko active Application Filing
- 2009-12-18 CN CN2009801517154A patent/CN102257010A/zh active Pending
- 2009-12-18 AU AU2009331900A patent/AU2009331900A1/en not_active Abandoned
- 2009-12-18 MX MX2011006641A patent/MX2011006641A/es active IP Right Grant
- 2009-12-18 KR KR1020137019063A patent/KR101777899B1/ko active IP Right Grant
- 2009-12-18 PT PT97966295T patent/PT2379601T/pt unknown
- 2009-12-18 CN CN201710026240.2A patent/CN106990251B/zh active Active
- 2009-12-18 SI SI200931544A patent/SI2379601T1/sl unknown
- 2009-12-18 LT LTEP09796629.5T patent/LT2379601T/lt unknown
- 2009-12-18 EP EP09796629.5A patent/EP2379601B1/en active Active
- 2009-12-18 PL PL09796629T patent/PL2379601T3/pl unknown
- 2009-12-18 ES ES09796629.5T patent/ES2595981T3/es active Active
- 2009-12-18 BR BRPI0923544-2A patent/BRPI0923544B1/pt not_active IP Right Cessation
- 2009-12-18 HU HUE09796629A patent/HUE030478T2/en unknown
- 2009-12-21 AR ARP090104999A patent/AR074816A1/es unknown
- 2009-12-21 TW TW098143984A patent/TWI424162B/zh not_active IP Right Cessation
-
2011
- 2011-06-02 IL IL213343A patent/IL213343A0/en unknown
-
2013
- 2013-08-07 US US13/960,893 patent/US9547010B2/en active Active
-
2016
- 2016-10-25 HR HRP20161398TT patent/HRP20161398T1/hr unknown
- 2016-11-04 CY CY20161101134T patent/CY1118420T1/el unknown
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