AR074816A1 - Anticuerpo anti- idiotipo dirigido contra un anticuerpo dirigido contra el peptido beta amiloide - Google Patents
Anticuerpo anti- idiotipo dirigido contra un anticuerpo dirigido contra el peptido beta amiloideInfo
- Publication number
- AR074816A1 AR074816A1 ARP090104999A ARP090104999A AR074816A1 AR 074816 A1 AR074816 A1 AR 074816A1 AR P090104999 A ARP090104999 A AR P090104999A AR P090104999 A ARP090104999 A AR P090104999A AR 074816 A1 AR074816 A1 AR 074816A1
- Authority
- AR
- Argentina
- Prior art keywords
- antibody
- directed against
- beta
- peptide
- idiotipo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/686—Anti-idiotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Anticuerpo antiidiotipo que se une a la región determinante de la complementariedad de un anticuerpo dirigido contra el péptido beta-amiloide. En una realización, dicho anticuerpo se une al mismo epítopo o a un epítopo solapado que el anticuerpo obtenible de la línea celular DSM ACC2939. También se describe un inmunoensayo para la determinación de un anticuerpo dirigido contra el péptido beta-amiloide y para la determinación de un anticuerpo antiidiotipo que se une a un anticuerpo dirigido contra el péptido beta-amiloide.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08022235 | 2008-12-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR074816A1 true AR074816A1 (es) | 2011-02-16 |
Family
ID=40581970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP090104999A AR074816A1 (es) | 2008-12-22 | 2009-12-21 | Anticuerpo anti- idiotipo dirigido contra un anticuerpo dirigido contra el peptido beta amiloide |
Country Status (22)
Country | Link |
---|---|
US (2) | US8614297B2 (es) |
EP (1) | EP2379601B1 (es) |
JP (1) | JP5642702B2 (es) |
KR (2) | KR20110086182A (es) |
CN (2) | CN106990251B (es) |
AR (1) | AR074816A1 (es) |
AU (1) | AU2009331900A1 (es) |
BR (1) | BRPI0923544B1 (es) |
CA (1) | CA2746779C (es) |
CY (1) | CY1118420T1 (es) |
DK (1) | DK2379601T3 (es) |
ES (1) | ES2595981T3 (es) |
HR (1) | HRP20161398T1 (es) |
HU (1) | HUE030478T2 (es) |
IL (1) | IL213343A0 (es) |
LT (1) | LT2379601T (es) |
MX (2) | MX352117B (es) |
PL (1) | PL2379601T3 (es) |
PT (1) | PT2379601T (es) |
SI (1) | SI2379601T1 (es) |
TW (1) | TWI424162B (es) |
WO (1) | WO2010072384A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
US9334319B2 (en) | 2012-04-20 | 2016-05-10 | Abbvie Inc. | Low acidic species compositions |
US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
WO2013177115A2 (en) * | 2012-05-21 | 2013-11-28 | Abbvie Inc. | Novel purification of human, humanized, or chimeric antibodies using protein a affinity chromatography |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
CA2905010A1 (en) | 2013-03-12 | 2014-09-18 | Abbvie Inc. | Human antibodies that bind human tnf-alpha and methods of preparing the same |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
US9598667B2 (en) | 2013-10-04 | 2017-03-21 | Abbvie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
EP3176580A1 (en) | 2015-12-01 | 2017-06-07 | Roche Diagnostics GmbH | Method for reduction of interferences in immunoassays |
EP3508849B1 (en) * | 2016-08-31 | 2023-04-19 | Eiken Kagaku Kabushiki Kaisha | Antibody measurement method using antigen-carrying insoluble carrier particles on which antigen is immobilized by different methods, and reagent for antibody measurement |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5219730A (en) | 1982-09-28 | 1993-06-15 | New York University | Idiotype-anti-idiotype immunoassay |
US4828981A (en) | 1983-08-24 | 1989-05-09 | Synbiotics Corporation | Immunoassays for determining Dirofilaria immitis infection using antiidiotype monoclonal antibody reagents |
EP0170302A1 (fr) | 1984-06-27 | 1986-02-05 | l'Association internationale à but scientifique, dite: Institut international de pathologie cellulaire et moléculaire | Procédé de dosage immunologique d'une substance dans un échantillon liquide au moyen d'anticorps anti-idiotypiques |
US5238808A (en) | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
US4666829A (en) | 1985-05-15 | 1987-05-19 | University Of California | Polypeptide marker for Alzheimer's disease and its use for diagnosis |
EP0243471A4 (en) | 1985-10-22 | 1989-07-11 | Cooper Lipotech Inc | SOLID PHASE LIPOSOME IMMUNOANALYSIS SYSTEM. |
SG60022A1 (en) | 1988-11-03 | 1999-02-22 | Igen Inc | Electrochemicalmiliuminescent assays |
US5068088A (en) | 1988-11-03 | 1991-11-26 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescent measurements |
JPH04507285A (ja) | 1988-12-09 | 1992-12-17 | セントコー・インコーポレーテッド | 抗イディオトープ免疫検定法 |
IL100866A (en) | 1991-02-06 | 1995-10-31 | Igen Inc | Luminescence test method and device based on magnetic tiny particles, containing many magnets |
WO1994001451A2 (en) | 1992-07-13 | 1994-01-20 | Bionebraska, Inc. | Method for modification of recombinant polypeptides |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US7179892B2 (en) | 2000-12-06 | 2007-02-20 | Neuralab Limited | Humanized antibodies that recognize beta amyloid peptide |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
KR100767146B1 (ko) | 2000-02-24 | 2007-10-15 | 워싱톤 유니버시티 | Aβ 펩티드를 격리시키는 인간화 항체 |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
TWI255272B (en) | 2000-12-06 | 2006-05-21 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
CA2451998A1 (en) | 2001-08-17 | 2003-02-27 | Eli Lilly And Company | Anti-a.beta. antibodies |
AR038568A1 (es) | 2002-02-20 | 2005-01-19 | Hoffmann La Roche | Anticuerpos anti-a beta y su uso |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
WO2004092197A2 (en) | 2003-04-07 | 2004-10-28 | The Regents Of The University Of California | Amyloid-specific peptides and uses thereof |
PE20050627A1 (es) | 2003-05-30 | 2005-08-10 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido beta amiloideo |
JP2007527865A (ja) | 2003-09-12 | 2007-10-04 | ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 種々の配列を有するタンパク質から形成されたアミロイドに共通の高分子量凝集中間体に特異的なモノクローナル抗体 |
EP1680666A4 (en) | 2003-10-27 | 2008-03-26 | Monogram Biosciences Inc | ANTI-THERAPEUTIC HUMAN ANTIBODY DETECTION |
JPWO2005105998A1 (ja) | 2004-04-27 | 2008-07-31 | 財団法人化学及血清療法研究所 | ヒト抗アミロイドβペプチド抗体およびその抗体フラグメント |
WO2006036291A2 (en) | 2004-07-30 | 2006-04-06 | Rinat Neuroscience Corp. | Antibodies directed against amyloid-beta peptide and methods using same |
AR051528A1 (es) | 2004-12-15 | 2007-01-17 | Neuralab Ltd | Anticuerpos humanizados que reconocen el peptido beta amiloideo |
PE20061323A1 (es) | 2005-04-29 | 2007-02-09 | Rinat Neuroscience Corp | Anticuerpos dirigidos contra el peptido amiloide beta y metodos que utilizan los mismos |
AU2007222584B2 (en) | 2006-03-09 | 2012-07-12 | F. Hoffmann-La Roche Ag | Anti-drug antibody assay |
EP1917854A1 (en) | 2006-11-06 | 2008-05-07 | F. Hoffmann-La Roche Ag | Method for producing anti idiotypic antibodies |
US20080127359A1 (en) * | 2006-11-06 | 2008-05-29 | Hermann Beck | Method for producing anti-idiotypic antibodies |
TWI434855B (zh) * | 2006-11-21 | 2014-04-21 | Hoffmann La Roche | 結合物及其在免疫分析中作為參考標準之用途 |
-
2009
- 2009-12-15 US US12/637,833 patent/US8614297B2/en active Active
- 2009-12-18 HU HUE09796629A patent/HUE030478T2/en unknown
- 2009-12-18 DK DK09796629.5T patent/DK2379601T3/en active
- 2009-12-18 ES ES09796629.5T patent/ES2595981T3/es active Active
- 2009-12-18 SI SI200931544A patent/SI2379601T1/sl unknown
- 2009-12-18 WO PCT/EP2009/009160 patent/WO2010072384A1/en active Application Filing
- 2009-12-18 JP JP2011542710A patent/JP5642702B2/ja active Active
- 2009-12-18 BR BRPI0923544-2A patent/BRPI0923544B1/pt not_active IP Right Cessation
- 2009-12-18 MX MX2014009062A patent/MX352117B/es unknown
- 2009-12-18 KR KR1020117014278A patent/KR20110086182A/ko active Application Filing
- 2009-12-18 LT LTEP09796629.5T patent/LT2379601T/lt unknown
- 2009-12-18 CN CN201710026240.2A patent/CN106990251B/zh active Active
- 2009-12-18 EP EP09796629.5A patent/EP2379601B1/en active Active
- 2009-12-18 KR KR1020137019063A patent/KR101777899B1/ko active IP Right Grant
- 2009-12-18 AU AU2009331900A patent/AU2009331900A1/en not_active Abandoned
- 2009-12-18 PT PT97966295T patent/PT2379601T/pt unknown
- 2009-12-18 PL PL09796629T patent/PL2379601T3/pl unknown
- 2009-12-18 CA CA2746779A patent/CA2746779C/en active Active
- 2009-12-18 CN CN2009801517154A patent/CN102257010A/zh active Pending
- 2009-12-18 MX MX2011006641A patent/MX2011006641A/es active IP Right Grant
- 2009-12-21 TW TW098143984A patent/TWI424162B/zh not_active IP Right Cessation
- 2009-12-21 AR ARP090104999A patent/AR074816A1/es unknown
-
2011
- 2011-06-02 IL IL213343A patent/IL213343A0/en unknown
-
2013
- 2013-08-07 US US13/960,893 patent/US9547010B2/en active Active
-
2016
- 2016-10-25 HR HRP20161398TT patent/HRP20161398T1/hr unknown
- 2016-11-04 CY CY20161101134T patent/CY1118420T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR074816A1 (es) | Anticuerpo anti- idiotipo dirigido contra un anticuerpo dirigido contra el peptido beta amiloide | |
AR101846A1 (es) | Anticuerpos anti-cll-1 e inmunoconjugados | |
CL2013003214A1 (es) | Formulacion estable que comprende al menos un anticuerpo monoclonal que se une especificamente a pcsk9, un tampon, un surfactante y al menos un estabilizador; y su uso para tratar o prevenir enfermedades relacionadas con el colesterol. | |
CL2008003782A1 (es) | Anticuerpo bivalente bioespecifico que comprende la cadena ligera y pesada de un anticuerpo que se une a un primer antigeno donde el dominio ch3 se reemplaza por ch1, y la cadena ligera y pesada de un anticuerpo que se une a un segundo antigeno, en el que el dominio ch3 esta reemplazado por cl; metodo de preparacion; y composicion. | |
EA200970210A1 (ru) | Prlr-специфическое антитело и его применения | |
CL2007003771A1 (es) | Polinucleotido que codifica antigeno de n. meningitidis; vector y celula huesped que lo comprenden; polipeptido codificado; anticuerpo que se une al polipeptido; composicion que comprende el polinucleotido, vector, celula, polipeptido o anticuerpo an | |
AR060241A1 (es) | Composiciones y metodos de uso para anticuerpos de c-met | |
CR20160206A (es) | Composiciones y métodos para anticuerpos que se dirigen a la proteína de complemento C5 | |
CR20130621A (es) | Anticuerpos anti-angptl3 y usos de los mismos | |
CL2013002888A1 (es) | Anticuerpo que se une peptido antigenico que se obtiene a partir de una proteina tau; composicion farmaceutica que comprende; uso para tratar trastorno o enfermedad neurodegenerativa;kit de ensayo, linea celular (div 2457-2011). | |
CR20120310A (es) | Anticuerpos neutralizadores contra el receptor de prolactina y su uso terapéutico | |
PE20140806A1 (es) | Anticuerpos anti-factor d humanizados y sus usos | |
CL2007003622A1 (es) | Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales. | |
CU24058B1 (es) | Antagonistas de pcsk9 | |
CL2008001741A1 (es) | Anticuerpo quimerico o humanizado o fragmento de los mismos que se unen especificamente a por lo menos un epitope en la proteina beta-amiloide; molecula de acido nucleico que lo codifica; composicion que lo comprende; y su uso para tratar enfermedades asociados con la formacion de placas amiloides. | |
RS53291B (en) | BETA 1-42 SPECIFIC MONOCLONIC ANTIBODIES WITH THERAPEUTIC PROPERTIES | |
TR201901841T4 (tr) | Her antikorlarının sabit dozlaması. | |
UA106070C2 (uk) | Антитіло, що специфічно зв'язується з egfr і her3 | |
CL2011002380A1 (es) | Anticuerpo multiespecifico que comprende un anticuerpo de longitud completa que se une especificamente a un primer antigeno y uno o mas fragmentos fab de cadena sencilla que se unen a uno o mas antigenos, acido nucleico que lo codifica; y composicion farmaceutica que lo comprende. | |
PE20141787A1 (es) | Composiciones anti-cgrp y uso de las mismas | |
CR11691A (es) | Anticuerpos monoclonales contra la proteína rgm a y sus usos | |
CR20120127A (es) | Anticuerpos monoclonales | |
CL2012000914A1 (es) | Anticuerpos monoclonales que se unen especificamente a la region c-terminal de progastrina. uso para la preparacion de un medicamento util en el tratamiento de cancer colorectal. | |
AR082630A1 (es) | Anticuerpos anti-tenascina-c a2 y metodos de uso | |
CL2007002879A1 (es) | Anticuerpo monoclonal contra nectina-2; celula de hibridoma que lo produce; composicion farmaceutica que lo comprende; y su uso para tratar cancer. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |