MX349947B - Metodos de tratamiento de inflamacion neurogenica cronica usando una toxina clostridial modificada. - Google Patents
Metodos de tratamiento de inflamacion neurogenica cronica usando una toxina clostridial modificada.Info
- Publication number
- MX349947B MX349947B MX2014001306A MX2014001306A MX349947B MX 349947 B MX349947 B MX 349947B MX 2014001306 A MX2014001306 A MX 2014001306A MX 2014001306 A MX2014001306 A MX 2014001306A MX 349947 B MX349947 B MX 349947B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- clostridial toxin
- treating chronic
- modified clostridial
- neurogenic inflammation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Gynecology & Obstetrics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Pregnancy & Childbirth (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invención se refiere a método para prolongar el tiempo de clímax en un paciente con necesidad del mismo, como son los métodos para tratar la eyaculación precoz mediante la administración local de una neurotoxina clostridial, tal como una neurotoxina botulínica, al paciente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/548,073 US8147848B2 (en) | 2009-08-26 | 2009-08-26 | Method for treating premature ejaculation with a botulinum neurotoxin |
PCT/US2010/044959 WO2011028371A1 (en) | 2009-08-26 | 2010-08-10 | Methods of treating chronic neurogenic inflammation using a modified clostridial toxin |
Publications (1)
Publication Number | Publication Date |
---|---|
MX349947B true MX349947B (es) | 2017-08-22 |
Family
ID=43127150
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014001306A MX349947B (es) | 2009-08-26 | 2010-08-10 | Metodos de tratamiento de inflamacion neurogenica cronica usando una toxina clostridial modificada. |
MX2012002378A MX2012002378A (es) | 2009-08-26 | 2010-08-10 | Metodos de tratamiento de inflamacion neurogenica cronica usando una toxina clostridial modificada. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012002378A MX2012002378A (es) | 2009-08-26 | 2010-08-10 | Metodos de tratamiento de inflamacion neurogenica cronica usando una toxina clostridial modificada. |
Country Status (19)
Country | Link |
---|---|
US (8) | US8147848B2 (es) |
EP (2) | EP2708239B1 (es) |
JP (2) | JP5766699B2 (es) |
KR (1) | KR101612988B1 (es) |
CN (2) | CN103816530B (es) |
AU (2) | AU2010289969B2 (es) |
BR (1) | BR112012004246A2 (es) |
CA (1) | CA2772372C (es) |
CY (1) | CY1114792T1 (es) |
DK (2) | DK2470202T3 (es) |
ES (2) | ES2564677T3 (es) |
HK (2) | HK1171658A1 (es) |
IN (1) | IN2012DN02210A (es) |
MX (2) | MX349947B (es) |
PL (1) | PL2470202T3 (es) |
PT (1) | PT2470202E (es) |
RU (1) | RU2568844C2 (es) |
SI (1) | SI2470202T1 (es) |
WO (1) | WO2011028371A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8147848B2 (en) | 2009-08-26 | 2012-04-03 | Allergan, Inc. | Method for treating premature ejaculation with a botulinum neurotoxin |
US20120251518A1 (en) * | 2011-03-29 | 2012-10-04 | Allergan, Inc. | Endopeptidase Treatment of Sexual Dysfunction Disorders |
US20130066148A1 (en) * | 2011-09-12 | 2013-03-14 | Kang Seon Cho | Method of augmenting glans |
EP2649985A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (III) |
EP2649983A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (II) |
EP2649984A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis |
AU2013246882B2 (en) | 2012-04-13 | 2017-10-19 | Lubrizol Advanced Materials, Inc. | Compounds which inhibit neuronal exocytosis (II) |
US9764010B2 (en) | 2012-08-24 | 2017-09-19 | Allergan, Inc. | Method for treating premature ejaculation with a neurotoxin |
SG11201701619TA (en) * | 2014-09-02 | 2017-03-30 | American Silver Llc | Botulinum toxin and colloidal silver particles |
RU2565104C1 (ru) * | 2014-10-24 | 2015-10-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения Российской Федерации (ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздрава России) | Способ лечения преждевременной эякуляции |
CN110996979A (zh) * | 2017-05-18 | 2020-04-10 | 雷文斯治疗公司 | 颈肌张力障碍的治疗方法 |
WO2018220232A1 (en) * | 2017-06-02 | 2018-12-06 | Universite De Versailles-St Quentin En Yvelines | Pharmaceutical combination product comprising botulinum toxin for the treatment of erectile dysfunction |
Family Cites Families (37)
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GB9120306D0 (en) | 1991-09-24 | 1991-11-06 | Graham Herbert K | Method and compositions for the treatment of cerebral palsy |
US5437291A (en) | 1993-08-26 | 1995-08-01 | Univ Johns Hopkins | Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction |
US5427291A (en) | 1993-09-21 | 1995-06-27 | Smith; David S. | Ski carrier and method employing same |
AU688452B2 (en) | 1993-12-28 | 1998-03-12 | Allergan, Inc. | Botulinum toxins for treating various disorders and associated pain |
US5766605A (en) | 1994-04-15 | 1998-06-16 | Mount Sinai School Of Medicine Of The City University Of New York | Treatment of autonomic nerve dysfunction with botulinum toxin |
CN1123680A (zh) * | 1994-11-18 | 1996-06-05 | 吕建京 | 一种对于肺脾肾虚有良好功效的保健品及其制造方法 |
ES2385130T3 (es) | 1997-07-15 | 2012-07-18 | The Regents Of The University Of Colorado, A Body Corporate | Uso de terapia con neurotoxinas para el tratamiento de enfermedades urológicas y de enfermedades relacionadas |
US6063768A (en) | 1997-09-04 | 2000-05-16 | First; Eric R. | Application of botulinum toxin to the management of neurogenic inflammatory disorders |
US6593335B1 (en) | 1997-12-18 | 2003-07-15 | Abbott Laboratories | Potassium channel openers |
US6727283B2 (en) | 1998-10-13 | 2004-04-27 | Pfizer Inc. | Sertraline oral concentrate |
CN1146866C (zh) * | 1998-11-17 | 2004-04-21 | 阿尔卑斯电气株式会社 | 浮起式磁头的冠顶形成方法及冠顶形成装置 |
FR2793689B1 (fr) | 1999-05-19 | 2001-08-24 | Pf Medicament | Dispositif transdermique pour l'administration de testosterone ou d'un de ses derives |
US20060216313A1 (en) * | 1999-08-10 | 2006-09-28 | Allergan, Inc. | Methods for treating a stricture with a botulinum toxin |
RU2180591C2 (ru) * | 1999-12-24 | 2002-03-20 | Государственное научное предприятие Московский научно-исследовательский институт психиатрии МЗ РФ | Средство для лечения сексуальных дисфункций у мужчин |
US6495154B1 (en) | 2000-11-21 | 2002-12-17 | Vivus Inc. | On demand administration of clomipramine and salts thereof to treat premature ejaculation |
US20020086036A1 (en) | 2000-12-05 | 2002-07-04 | Allergan Sales, Inc. | Methods for treating hyperhidrosis |
WO2002074241A2 (en) | 2001-03-16 | 2002-09-26 | Dmi Biosciences Inc. | Method of delaying ejaculation |
EP1373203A1 (en) | 2001-03-29 | 2004-01-02 | Bristol-Myers Squibb Company | Cyclopropylindole derivatives as selective serotonin reuptake inhibitors |
US20030113349A1 (en) | 2001-12-18 | 2003-06-19 | Coleman William P. | Topically applied clostridium botulinum toxin compositions and treatment methods |
ATE406900T1 (de) * | 2002-01-25 | 2008-09-15 | Modular Properties Ltd | Verfahren und zusammensetzungen zur behandlung der männlichen erektionsstörung |
US6776991B2 (en) * | 2002-06-26 | 2004-08-17 | Allergan, Inc. | Methods for treating priapism |
US20040009180A1 (en) | 2002-07-11 | 2004-01-15 | Allergan, Inc. | Transdermal botulinum toxin compositions |
TW200418838A (en) | 2002-09-18 | 2004-10-01 | Bristol Myers Squibb Co | Compounds for the treatment of premature ejaculation |
US20070264373A1 (en) * | 2004-01-26 | 2007-11-15 | Ian Carroll | Toxin Induced Sympathectomy |
US20060100584A1 (en) | 2004-08-10 | 2006-05-11 | Orest Olejnik | Needleless microprotrusion elastoplast system |
US20080220021A1 (en) | 2005-02-14 | 2008-09-11 | Pankaj Modi | Topical Botulinum Toxin Compositions for the Treatment of Hyperhidrosis |
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US8147848B2 (en) | 2009-08-26 | 2012-04-03 | Allergan, Inc. | Method for treating premature ejaculation with a botulinum neurotoxin |
US9049616B2 (en) | 2012-03-29 | 2015-06-02 | Broadcom Corporation | Session recovery after network coordinator or AP restart for single user, multiple user, multiple access, and/or MIMO wireless communications |
US9764010B2 (en) | 2012-08-24 | 2017-09-19 | Allergan, Inc. | Method for treating premature ejaculation with a neurotoxin |
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2009
- 2009-08-26 US US12/548,073 patent/US8147848B2/en not_active Expired - Fee Related
-
2010
- 2010-08-10 MX MX2014001306A patent/MX349947B/es unknown
- 2010-08-10 WO PCT/US2010/044959 patent/WO2011028371A1/en active Application Filing
- 2010-08-10 JP JP2012526812A patent/JP5766699B2/ja not_active Expired - Fee Related
- 2010-08-10 PL PL10742993T patent/PL2470202T3/pl unknown
- 2010-08-10 RU RU2012110324/15A patent/RU2568844C2/ru active
- 2010-08-10 DK DK10742993.8T patent/DK2470202T3/da active
- 2010-08-10 ES ES13188887.7T patent/ES2564677T3/es active Active
- 2010-08-10 IN IN2210DEN2012 patent/IN2012DN02210A/en unknown
- 2010-08-10 BR BR112012004246A patent/BR112012004246A2/pt not_active Application Discontinuation
- 2010-08-10 CN CN201410067182.4A patent/CN103816530B/zh not_active Expired - Fee Related
- 2010-08-10 SI SI201030508T patent/SI2470202T1/sl unknown
- 2010-08-10 EP EP13188887.7A patent/EP2708239B1/en active Active
- 2010-08-10 ES ES10742993.8T patent/ES2446969T3/es active Active
- 2010-08-10 PT PT107429938T patent/PT2470202E/pt unknown
- 2010-08-10 DK DK13188887.7T patent/DK2708239T3/en active
- 2010-08-10 CN CN201080048073.8A patent/CN102802663B/zh not_active Expired - Fee Related
- 2010-08-10 EP EP10742993.8A patent/EP2470202B1/en active Active
- 2010-08-10 CA CA2772372A patent/CA2772372C/en not_active Expired - Fee Related
- 2010-08-10 AU AU2010289969A patent/AU2010289969B2/en not_active Ceased
- 2010-08-10 KR KR1020127007553A patent/KR101612988B1/ko active IP Right Grant
- 2010-08-10 MX MX2012002378A patent/MX2012002378A/es active IP Right Grant
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2012
- 2012-02-22 US US13/402,755 patent/US8329193B2/en active Active
- 2012-10-18 US US13/654,808 patent/US8617570B2/en not_active Expired - Fee Related
- 2012-12-03 HK HK12112423.8A patent/HK1171658A1/xx not_active IP Right Cessation
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2013
- 2013-11-15 US US14/081,993 patent/US8916177B2/en not_active Expired - Fee Related
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2014
- 2014-01-29 CY CY20141100075T patent/CY1114792T1/el unknown
- 2014-07-30 HK HK14107738.6A patent/HK1194292A1/zh not_active IP Right Cessation
- 2014-11-06 US US14/534,913 patent/US9186395B2/en not_active Expired - Fee Related
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2015
- 2015-06-17 JP JP2015122108A patent/JP6078108B2/ja not_active Expired - Fee Related
- 2015-08-14 AU AU2015213381A patent/AU2015213381B2/en not_active Ceased
- 2015-11-16 US US14/942,424 patent/US9457069B2/en active Active
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2016
- 2016-10-03 US US15/283,734 patent/US9907841B2/en not_active Expired - Fee Related
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2018
- 2018-03-02 US US15/910,417 patent/US10420823B2/en not_active Expired - Fee Related
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