BR112012004246A2 - métodos para tratar inflamação neurogênica crônica usando uma toxina clostridial modificada - Google Patents
métodos para tratar inflamação neurogênica crônica usando uma toxina clostridial modificadaInfo
- Publication number
- BR112012004246A2 BR112012004246A2 BR112012004246A BR112012004246A BR112012004246A2 BR 112012004246 A2 BR112012004246 A2 BR 112012004246A2 BR 112012004246 A BR112012004246 A BR 112012004246A BR 112012004246 A BR112012004246 A BR 112012004246A BR 112012004246 A2 BR112012004246 A2 BR 112012004246A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- clostridial toxin
- treating chronic
- modified clostridial
- neurogenic inflammation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gynecology & Obstetrics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/548,073 US8147848B2 (en) | 2009-08-26 | 2009-08-26 | Method for treating premature ejaculation with a botulinum neurotoxin |
PCT/US2010/044959 WO2011028371A1 (en) | 2009-08-26 | 2010-08-10 | Methods of treating chronic neurogenic inflammation using a modified clostridial toxin |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012004246A2 true BR112012004246A2 (pt) | 2016-04-05 |
Family
ID=43127150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012004246A BR112012004246A2 (pt) | 2009-08-26 | 2010-08-10 | métodos para tratar inflamação neurogênica crônica usando uma toxina clostridial modificada |
Country Status (19)
Country | Link |
---|---|
US (8) | US8147848B2 (pt) |
EP (2) | EP2708239B1 (pt) |
JP (2) | JP5766699B2 (pt) |
KR (1) | KR101612988B1 (pt) |
CN (2) | CN102802663B (pt) |
AU (2) | AU2010289969B2 (pt) |
BR (1) | BR112012004246A2 (pt) |
CA (1) | CA2772372C (pt) |
CY (1) | CY1114792T1 (pt) |
DK (2) | DK2470202T3 (pt) |
ES (2) | ES2446969T3 (pt) |
HK (2) | HK1171658A1 (pt) |
IN (1) | IN2012DN02210A (pt) |
MX (2) | MX349947B (pt) |
PL (1) | PL2470202T3 (pt) |
PT (1) | PT2470202E (pt) |
RU (1) | RU2568844C2 (pt) |
SI (1) | SI2470202T1 (pt) |
WO (1) | WO2011028371A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8147848B2 (en) | 2009-08-26 | 2012-04-03 | Allergan, Inc. | Method for treating premature ejaculation with a botulinum neurotoxin |
US20120251518A1 (en) * | 2011-03-29 | 2012-10-04 | Allergan, Inc. | Endopeptidase Treatment of Sexual Dysfunction Disorders |
US20130066148A1 (en) * | 2011-09-12 | 2013-03-14 | Kang Seon Cho | Method of augmenting glans |
EP2649983A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (II) |
EP2649984A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis |
BR112014025396B1 (pt) | 2012-04-13 | 2020-03-17 | Lubrizol Advanced Materials, Inc. | Composto, composição cosmética ou farmacêutica, e, uso de um composto |
EP2649985A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (III) |
US9764010B2 (en) * | 2012-08-24 | 2017-09-19 | Allergan, Inc. | Method for treating premature ejaculation with a neurotoxin |
JP6643324B2 (ja) * | 2014-09-02 | 2020-02-12 | アメリカン シルヴァー リミテッド ライアビリティ カンパニー | ボツリヌス毒素及びコロイド状銀粒子 |
RU2565104C1 (ru) * | 2014-10-24 | 2015-10-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения Российской Федерации (ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздрава России) | Способ лечения преждевременной эякуляции |
MX2019013716A (es) * | 2017-05-18 | 2020-10-12 | Revance Therapeutics Inc | Métodos de tratamiento para la distonía cervical. |
WO2018220232A1 (en) * | 2017-06-02 | 2018-12-06 | Universite De Versailles-St Quentin En Yvelines | Pharmaceutical combination product comprising botulinum toxin for the treatment of erectile dysfunction |
US12102556B2 (en) | 2022-05-31 | 2024-10-01 | Max Azevedo | System and method for fallopian birth control |
Family Cites Families (37)
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GB9120306D0 (en) | 1991-09-24 | 1991-11-06 | Graham Herbert K | Method and compositions for the treatment of cerebral palsy |
US5437291A (en) | 1993-08-26 | 1995-08-01 | Univ Johns Hopkins | Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction |
US5427291A (en) | 1993-09-21 | 1995-06-27 | Smith; David S. | Ski carrier and method employing same |
EP1477183B1 (en) | 1993-12-28 | 2005-11-02 | Allergan, Inc. | Neurotoxic component of Botulinum toxin for modulating cholinergic controlled secretions |
US5766605A (en) | 1994-04-15 | 1998-06-16 | Mount Sinai School Of Medicine Of The City University Of New York | Treatment of autonomic nerve dysfunction with botulinum toxin |
CN1123680A (zh) * | 1994-11-18 | 1996-06-05 | 吕建京 | 一种对于肺脾肾虚有良好功效的保健品及其制造方法 |
JP3692033B2 (ja) | 1997-07-15 | 2005-09-07 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド | 泌尿器疾患及び関連疾患の治療のための神経毒治療法の使用 |
US6063768A (en) | 1997-09-04 | 2000-05-16 | First; Eric R. | Application of botulinum toxin to the management of neurogenic inflammatory disorders |
US6593335B1 (en) | 1997-12-18 | 2003-07-15 | Abbott Laboratories | Potassium channel openers |
US6727283B2 (en) | 1998-10-13 | 2004-04-27 | Pfizer Inc. | Sertraline oral concentrate |
CN1146866C (zh) * | 1998-11-17 | 2004-04-21 | 阿尔卑斯电气株式会社 | 浮起式磁头的冠顶形成方法及冠顶形成装置 |
FR2793689B1 (fr) | 1999-05-19 | 2001-08-24 | Pf Medicament | Dispositif transdermique pour l'administration de testosterone ou d'un de ses derives |
US20060216313A1 (en) * | 1999-08-10 | 2006-09-28 | Allergan, Inc. | Methods for treating a stricture with a botulinum toxin |
RU2180591C2 (ru) * | 1999-12-24 | 2002-03-20 | Государственное научное предприятие Московский научно-исследовательский институт психиатрии МЗ РФ | Средство для лечения сексуальных дисфункций у мужчин |
US6495154B1 (en) | 2000-11-21 | 2002-12-17 | Vivus Inc. | On demand administration of clomipramine and salts thereof to treat premature ejaculation |
US20020086036A1 (en) | 2000-12-05 | 2002-07-04 | Allergan Sales, Inc. | Methods for treating hyperhidrosis |
EP1397126B9 (en) | 2001-03-16 | 2007-02-21 | DMI Biosciences, Inc. | Use of tramadol for delaying ejaculation |
PL364580A1 (en) | 2001-03-29 | 2004-12-13 | Bristol-Myers Squibb Company | Cyclopropylindole derivatives as selective serotonin reuptake inhibitors |
US20030113349A1 (en) | 2001-12-18 | 2003-06-19 | Coleman William P. | Topically applied clostridium botulinum toxin compositions and treatment methods |
PT1474143E (pt) * | 2002-01-25 | 2009-01-02 | Modular Properties Ltd | Métodos e composições para tratar a disfunção eréctil masculina |
US6776991B2 (en) * | 2002-06-26 | 2004-08-17 | Allergan, Inc. | Methods for treating priapism |
US20040009180A1 (en) | 2002-07-11 | 2004-01-15 | Allergan, Inc. | Transdermal botulinum toxin compositions |
TW200418838A (en) * | 2002-09-18 | 2004-10-01 | Bristol Myers Squibb Co | Compounds for the treatment of premature ejaculation |
WO2005072433A2 (en) * | 2004-01-26 | 2005-08-11 | The Board Of Trustees Of The Leland Stanford Junior University | Toxin induced sympathectomy |
US20060100584A1 (en) | 2004-08-10 | 2006-05-11 | Orest Olejnik | Needleless microprotrusion elastoplast system |
US20080220021A1 (en) | 2005-02-14 | 2008-09-11 | Pankaj Modi | Topical Botulinum Toxin Compositions for the Treatment of Hyperhidrosis |
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US20090005319A1 (en) * | 2007-07-01 | 2009-01-01 | Barone Jr Frank V | Topical compositions for delaying ejaculation and methods of using the same |
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SG185338A1 (en) | 2007-10-23 | 2012-11-29 | Allergan Inc | Methods of treating urogenital-neurological disorders using modified clostridial toxins |
US8147848B2 (en) | 2009-08-26 | 2012-04-03 | Allergan, Inc. | Method for treating premature ejaculation with a botulinum neurotoxin |
US9049616B2 (en) | 2012-03-29 | 2015-06-02 | Broadcom Corporation | Session recovery after network coordinator or AP restart for single user, multiple user, multiple access, and/or MIMO wireless communications |
US9764010B2 (en) | 2012-08-24 | 2017-09-19 | Allergan, Inc. | Method for treating premature ejaculation with a neurotoxin |
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2009
- 2009-08-26 US US12/548,073 patent/US8147848B2/en not_active Expired - Fee Related
-
2010
- 2010-08-10 DK DK10742993.8T patent/DK2470202T3/da active
- 2010-08-10 AU AU2010289969A patent/AU2010289969B2/en not_active Ceased
- 2010-08-10 MX MX2014001306A patent/MX349947B/es unknown
- 2010-08-10 CN CN201080048073.8A patent/CN102802663B/zh not_active Expired - Fee Related
- 2010-08-10 EP EP13188887.7A patent/EP2708239B1/en active Active
- 2010-08-10 BR BR112012004246A patent/BR112012004246A2/pt not_active Application Discontinuation
- 2010-08-10 DK DK13188887.7T patent/DK2708239T3/en active
- 2010-08-10 CN CN201410067182.4A patent/CN103816530B/zh not_active Expired - Fee Related
- 2010-08-10 JP JP2012526812A patent/JP5766699B2/ja not_active Expired - Fee Related
- 2010-08-10 MX MX2012002378A patent/MX2012002378A/es active IP Right Grant
- 2010-08-10 ES ES10742993.8T patent/ES2446969T3/es active Active
- 2010-08-10 EP EP10742993.8A patent/EP2470202B1/en active Active
- 2010-08-10 CA CA2772372A patent/CA2772372C/en not_active Expired - Fee Related
- 2010-08-10 SI SI201030508T patent/SI2470202T1/sl unknown
- 2010-08-10 PT PT107429938T patent/PT2470202E/pt unknown
- 2010-08-10 WO PCT/US2010/044959 patent/WO2011028371A1/en active Application Filing
- 2010-08-10 ES ES13188887.7T patent/ES2564677T3/es active Active
- 2010-08-10 KR KR1020127007553A patent/KR101612988B1/ko active IP Right Grant
- 2010-08-10 RU RU2012110324/15A patent/RU2568844C2/ru active
- 2010-08-10 IN IN2210DEN2012 patent/IN2012DN02210A/en unknown
- 2010-08-10 PL PL10742993T patent/PL2470202T3/pl unknown
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2012
- 2012-02-22 US US13/402,755 patent/US8329193B2/en active Active
- 2012-10-18 US US13/654,808 patent/US8617570B2/en not_active Expired - Fee Related
- 2012-12-03 HK HK12112423.8A patent/HK1171658A1/xx not_active IP Right Cessation
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2013
- 2013-11-15 US US14/081,993 patent/US8916177B2/en not_active Expired - Fee Related
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2014
- 2014-01-29 CY CY20141100075T patent/CY1114792T1/el unknown
- 2014-07-30 HK HK14107738.6A patent/HK1194292A1/zh not_active IP Right Cessation
- 2014-11-06 US US14/534,913 patent/US9186395B2/en not_active Expired - Fee Related
-
2015
- 2015-06-17 JP JP2015122108A patent/JP6078108B2/ja not_active Expired - Fee Related
- 2015-08-14 AU AU2015213381A patent/AU2015213381B2/en not_active Ceased
- 2015-11-16 US US14/942,424 patent/US9457069B2/en active Active
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2016
- 2016-10-03 US US15/283,734 patent/US9907841B2/en not_active Expired - Fee Related
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2018
- 2018-03-02 US US15/910,417 patent/US10420823B2/en not_active Expired - Fee Related
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
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B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
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