MX349347B - Enfermedad tromboembolica. - Google Patents

Enfermedad tromboembolica.

Info

Publication number
MX349347B
MX349347B MX2013014622A MX2013014622A MX349347B MX 349347 B MX349347 B MX 349347B MX 2013014622 A MX2013014622 A MX 2013014622A MX 2013014622 A MX2013014622 A MX 2013014622A MX 349347 B MX349347 B MX 349347B
Authority
MX
Mexico
Prior art keywords
thromboemoblic
disease markers
relates
thromboembolism
risk
Prior art date
Application number
MX2013014622A
Other languages
English (en)
Other versions
MX2013014622A (es
Inventor
Eduardo Salas
José Manuel Soria
Miroslava Ogorelkova
Roberto Elosua
Sergio Castillo
Joan S Vila
Original Assignee
Gendiag Exe Sl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46320920&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX349347(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gendiag Exe Sl filed Critical Gendiag Exe Sl
Publication of MX2013014622A publication Critical patent/MX2013014622A/es
Publication of MX349347B publication Critical patent/MX349347B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invención se refiere a un procedimiento para una evaluación más apropiada del riesgo de un acontecimiento tromboembólico basándose en la presencia de diferentes variantes genéticas. La invención también se refiere a un procedimiento para determinar el riesgo de padecer una enfermedad tromboembólica combinando la ausencia o la presencia de uno o más marcadores polimórficos en una muestra del sujeto que presenta factores de riesgo convencionales para tromboembolia así como también a medios implementados por computadora para llevar a cabo dicho procedimiento.
MX2013014622A 2011-06-16 2012-06-13 Enfermedad tromboembolica. MX349347B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11170235.3A EP2535424B1 (en) 2011-06-16 2011-06-16 SNPs associated with thromboemoblic disease
PCT/EP2012/061185 WO2012171949A2 (en) 2011-06-16 2012-06-13 Thromboembolic disease

Publications (2)

Publication Number Publication Date
MX2013014622A MX2013014622A (es) 2014-03-27
MX349347B true MX349347B (es) 2017-07-25

Family

ID=46320920

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013014622A MX349347B (es) 2011-06-16 2012-06-13 Enfermedad tromboembolica.
MX2017009492A MX360663B (es) 2011-06-16 2012-06-13 Enfermedad tromboembolica.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2017009492A MX360663B (es) 2011-06-16 2012-06-13 Enfermedad tromboembolica.

Country Status (16)

Country Link
US (2) US9518297B2 (es)
EP (3) EP2535424B1 (es)
AR (1) AR086734A1 (es)
AU (1) AU2012269112B2 (es)
BR (1) BR112013032352A2 (es)
CA (1) CA2839368C (es)
CL (1) CL2013003605A1 (es)
DK (2) DK2535424T3 (es)
DO (1) DOP2013000296A (es)
ES (2) ES2547075T3 (es)
MX (2) MX349347B (es)
NO (1) NO2721172T3 (es)
PE (1) PE20141069A1 (es)
PT (2) PT2535424E (es)
RU (1) RU2606758C2 (es)
WO (1) WO2012171949A2 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10557170B2 (en) 2011-06-16 2020-02-11 Gendiag.Exe, S.L. Thromboembolic disease markers
ES2547075T3 (es) 2011-06-16 2015-10-01 Gendiag.Exe, S.L. SNP asociados a enfermedad tromboembólica
EP4286517A3 (en) 2013-04-04 2024-03-13 President and Fellows of Harvard College Therapeutic uses of genome editing with crispr/cas systems
WO2016160721A1 (en) 2015-03-27 2016-10-06 President And Fellows Of Harvard College Modified t cells and methods of making and using the same
WO2017097854A1 (en) * 2015-12-08 2017-06-15 Umc Utrecht Holding B.V. Extracellular vesicle markers for stable angina and unstable angina
ES2911406T3 (es) * 2016-12-09 2022-05-19 Gene Gender S R L Método y kit para predecir el riesgo de trombosis venosa profunda y embolia pulmonar
WO2018104549A1 (en) * 2016-12-09 2018-06-14 Gene Predictis Sa Method for predicting the risk of deep vein thrombosis and pulmonary embolism associated with hormonal preparations and hormone levels
WO2018195129A1 (en) 2017-04-17 2018-10-25 University Of Maryland, College Park Embryonic cell cultures and methods of using the same
EP3631016A1 (en) * 2017-05-24 2020-04-08 Genincode UK, Ltd. Cancer-associated venous thromboembolic events
CA3090339A1 (en) * 2018-02-09 2019-08-15 Genincode Uk, Ltd. Prediction of pregnancy loss
CN108642163B (zh) * 2018-05-16 2021-10-22 江苏中济万泰生物医药有限公司 一种人类红细胞abo血型基因分型引物组及应用
RU2710213C1 (ru) * 2018-12-17 2019-12-25 Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) Способ определения вероятности церебральной и нецеребральной тромбоэмболии артерий большого круга кровообращения
EA038901B1 (ru) * 2019-09-27 2021-11-03 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр гематологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ гематологии" Минздрава России) Способ прогнозирования тромбоэмболических осложнений у женщин при носительстве мутаций гена протромбина [f2(20210)ga]
RU2722986C1 (ru) * 2019-12-24 2020-06-05 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр терапии и профилактической медицины" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ТПМ" Минздрава России) Способ прогнозирования дополнительного риска тромбоэмболических осложнений у пациентов старческого возраста с фибрилляцией предсердий
CN114410766A (zh) * 2021-11-24 2022-04-29 广州知力医学诊断技术有限公司 一种血栓与出凝血性疾病检测panel及其应用
EP4194568A1 (en) * 2021-12-10 2023-06-14 Genincode Uk Limited Covid-19-associated venous thromboembolism
CN114214402B (zh) * 2021-12-29 2024-02-09 江苏意诺飞生物科技有限公司 血液高凝或静脉血栓风险基因多态性检测引物组、试剂盒及检测方法和应用

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US1975A (en) 1841-02-12 Manner of constructing corn-shellers
US4883750A (en) 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
JP3163105B2 (ja) 1994-02-14 2001-05-08 リヤクス・ユニフアーシテイト・レイデン 血栓症及び／又は活性化プロテインｃに対する弱い抗凝血応答に関連した遺伝性欠陥の存在をスクリーニングする方法
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US20050026168A1 (en) * 2002-12-13 2005-02-03 Genesis Group Inc. Method for the detection of risk factors associated with myocardial infarction
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Also Published As

Publication number Publication date
RU2014101169A (ru) 2015-07-27
CL2013003605A1 (es) 2014-08-08
PT2535424E (pt) 2015-10-29
AR086734A1 (es) 2014-01-22
EP2535424B1 (en) 2015-08-05
AU2012269112A1 (en) 2014-01-30
DK2535424T3 (en) 2015-09-14
MX2013014622A (es) 2014-03-27
MX360663B (es) 2018-11-13
DK2721172T3 (en) 2018-02-19
US20140221230A1 (en) 2014-08-07
DOP2013000296A (es) 2014-03-31
WO2012171949A3 (en) 2013-02-21
US20160102355A1 (en) 2016-04-14
RU2606758C2 (ru) 2017-01-10
EP2721172B1 (en) 2018-01-10
EP2799556A3 (en) 2015-04-08
ES2663943T3 (es) 2018-04-17
EP2535424A1 (en) 2012-12-19
EP2721172A2 (en) 2014-04-23
NO2721172T3 (es) 2018-06-09
EP2799556A2 (en) 2014-11-05
BR112013032352A2 (pt) 2018-10-30
AU2012269112B2 (en) 2015-09-03
ES2547075T3 (es) 2015-10-01
US9518297B2 (en) 2016-12-13
CA2839368A1 (en) 2012-12-20
DK2721172T5 (en) 2018-02-26
WO2012171949A2 (en) 2012-12-20
US10023914B2 (en) 2018-07-17
PT2721172T (pt) 2018-02-21
PE20141069A1 (es) 2014-09-06
CA2839368C (en) 2018-12-04

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