MX348334B - Microorganismo y metodos para la biosintesis de butadieno. - Google Patents

Microorganismo y metodos para la biosintesis de butadieno.

Info

Publication number
MX348334B
MX348334B MX2013008988A MX2013008988A MX348334B MX 348334 B MX348334 B MX 348334B MX 2013008988 A MX2013008988 A MX 2013008988A MX 2013008988 A MX2013008988 A MX 2013008988A MX 348334 B MX348334 B MX 348334B
Authority
MX
Mexico
Prior art keywords
butadiene
naturally occurring
occurring microbial
methods
biosynthesis
Prior art date
Application number
MX2013008988A
Other languages
English (en)
Spanish (es)
Other versions
MX2013008988A (es
Inventor
E Osterhout Robin
Pharkya Priti
J Burk Mark
P Burgard Anthony
Sun Jun
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of MX2013008988A publication Critical patent/MX2013008988A/es
Publication of MX348334B publication Critical patent/MX348334B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/20—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms
    • C07C1/24—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms by elimination of water
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01036—Acetoacetyl-CoA reductase (1.1.1.36)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
    • C12Y103/01008—Acyl-CoA dehydrogenase (NADP+) (1.3.1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/08—Oxidoreductases acting on the CH-CH group of donors (1.3) with flavin as acceptor (1.3.8)
    • C12Y103/08006—Glutaryl-CoA dehydrogenase (1.3.8.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/99—Oxidoreductases acting on the CH-CH group of donors (1.3) with other acceptors (1.3.99)
    • C12Y103/99032—Glutaryl-CoA dehydrogenase (non-decarboxylating) (1.3.99.32)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01009—Acetyl-CoA C-acetyltransferase (2.3.1.9)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/0107—Glutaconyl-CoA decarboxylase (4.1.1.70)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01055—3-Hydroxybutyryl-CoA dehydratase (4.2.1.55)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/0112—4-Hydroxybutanoyl-CoA dehydratase (4.2.1.120)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y403/00—Carbon-nitrogen lyases (4.3)
    • C12Y403/01—Ammonia-lyases (4.3.1)
    • C12Y403/01014—3-Aminobutyryl-CoA ammonia-lyase (4.3.1.14)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2521/00—Catalysts comprising the elements, oxides or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium or hafnium
    • C07C2521/02—Boron or aluminium; Oxides or hydroxides thereof
    • C07C2521/04—Alumina
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2521/00—Catalysts comprising the elements, oxides or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium or hafnium
    • C07C2521/12—Silica and alumina
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2521/00—Catalysts comprising the elements, oxides or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium or hafnium
    • C07C2521/16—Clays or other mineral silicates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/10—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of rare earths
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/16—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
    • C07C2523/24—Chromium, molybdenum or tungsten
    • C07C2523/28—Molybdenum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/16—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
    • C07C2523/24—Chromium, molybdenum or tungsten
    • C07C2523/31—Chromium, molybdenum or tungsten combined with bismuth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of the iron group metals or copper
    • C07C2523/74—Iron group metals
    • C07C2523/745—Iron
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2527/00—Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • C07C2527/14—Phosphorus; Compounds thereof
    • C07C2527/16—Phosphorus; Compounds thereof containing oxygen
    • C07C2527/167—Phosphates or other compounds comprising the anion (PnO3n+1)(n+2)-
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2527/00—Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • C07C2527/14—Phosphorus; Compounds thereof
    • C07C2527/16—Phosphorus; Compounds thereof containing oxygen
    • C07C2527/167—Phosphates or other compounds comprising the anion (PnO3n+1)(n+2)-
    • C07C2527/173—Phosphoric acid or other acids with the formula Hn+2PnO3n+1
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX2013008988A 2011-02-02 2012-02-02 Microorganismo y metodos para la biosintesis de butadieno. MX348334B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161438947P 2011-02-02 2011-02-02
PCT/US2012/023632 WO2012106516A1 (en) 2011-02-02 2012-02-02 Microorganisms and methods for the biosynthesis of butadiene

Publications (2)

Publication Number Publication Date
MX2013008988A MX2013008988A (es) 2014-03-21
MX348334B true MX348334B (es) 2017-06-07

Family

ID=46603080

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013008988A MX348334B (es) 2011-02-02 2012-02-02 Microorganismo y metodos para la biosintesis de butadieno.

Country Status (13)

Country Link
US (4) US9321701B2 (OSRAM)
EP (1) EP2670852A4 (OSRAM)
JP (3) JP5960729B2 (OSRAM)
KR (1) KR20140145935A (OSRAM)
CN (2) CN106191132A (OSRAM)
AU (1) AU2012212118B2 (OSRAM)
BR (1) BR112013019811A2 (OSRAM)
CA (1) CA2826293A1 (OSRAM)
MX (1) MX348334B (OSRAM)
MY (2) MY162964A (OSRAM)
PH (1) PH12013501630A1 (OSRAM)
SG (1) SG192614A1 (OSRAM)
WO (1) WO2012106516A1 (OSRAM)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8129154B2 (en) 2008-06-17 2012-03-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
BRPI0922276A2 (pt) 2008-12-16 2015-08-04 Genomatica Inc "organismo microbiano de ocorrência não-natural, e , método para produzir isopropanol, 4-hidroxibutirato,e, 1,4-butanodiol."
EP2440669A4 (en) 2009-06-10 2013-08-28 Genomatica Inc MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL
KR20120120493A (ko) 2009-12-10 2012-11-01 게노마티카 인코포레이티드 합성 가스 또는 기타 가스상 탄소원 및 메탄올을 1,3-부탄디올로 변환하는 방법 및 변환용 유기체
JP5911847B2 (ja) 2010-05-05 2016-04-27 ジェノマティカ， インコーポレイテッド ブタジエンの生合成のための微生物および方法
BR112013019811A2 (pt) * 2011-02-02 2017-02-21 Genomatica Inc processo para a produção de butadieno e organismo microbiano que não ocorre naturalmente.
WO2012174439A2 (en) 2011-06-17 2012-12-20 Invista Technologies S.A R.L. Methods of producing four carbon molecules
US9422578B2 (en) 2011-06-17 2016-08-23 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
US9169486B2 (en) 2011-06-22 2015-10-27 Genomatica, Inc. Microorganisms for producing butadiene and methods related thereto
BR112014008061A2 (pt) 2011-10-19 2017-04-11 Scientist Of Fortune Sa método para a produção enzimática de butadieno
WO2013071074A1 (en) * 2011-11-11 2013-05-16 Invista North America S.A. R.L. Methods of producing butadiene
WO2014085612A1 (en) 2012-11-28 2014-06-05 INVISTA North America S.á r.l. Methods for biosynthesis of isobutene
CA2893431C (en) 2012-12-07 2021-12-07 Richard BOCKRATH Fermentative production of a hydrocarbon
AU2013354179B2 (en) 2012-12-07 2018-10-18 Global Bioenergies Improved fermentation method
JP2014161252A (ja) * 2013-02-22 2014-09-08 Sekisui Chem Co Ltd 組換え細胞
WO2014152434A2 (en) 2013-03-15 2014-09-25 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
US10294496B2 (en) 2013-07-19 2019-05-21 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
WO2015021059A1 (en) 2013-08-05 2015-02-12 INVISTA North America S.á r.l. Methods for biosynthesis of isobutene
US9862973B2 (en) 2013-08-05 2018-01-09 Invista North America S.A.R.L. Methods for biosynthesis of isoprene
WO2015084633A1 (en) 2013-12-03 2015-06-11 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
CA2935069C (en) 2013-12-27 2023-05-09 Genomatica, Inc. Methods and organisms with increased carbon flux efficiencies
BR112016029382A2 (pt) 2014-06-16 2017-10-17 Invista Tech Sarl processo para a produção de glutarato e éster metílico de ácido glutárico
WO2016004334A1 (en) 2014-07-03 2016-01-07 Genomatica, Inc. Microorganisms for producing 4c-5c compounds with unsaturation and methods related thereto
WO2016007196A1 (en) * 2014-07-07 2016-01-14 Cobalt Technologies, Inc. Biomass conversion to butadiene
CN107208118A (zh) 2014-09-18 2017-09-26 基因组股份公司 具有提高的能源效率的非天然微生物
CN104298866B (zh) * 2014-09-30 2017-06-06 杭州电子科技大学 一种克劳斯硫磺回收过程中反应炉动态建模方法
WO2016066873A1 (es) 2014-10-30 2016-05-06 Abengoa Research, S.L. Óxidos mixtos que comprenden magnesio y boro, y su uso como catalizadores para producir precursores de butadieno
WO2016066869A1 (es) 2014-10-30 2016-05-06 Abengoa Research, S.L. Catalizador microporoso con encapsulación selectiva de óxidos metálicos útil para producir precursores de butadieno
US10196326B2 (en) * 2015-02-23 2019-02-05 Versalis S.P.A. Process for the production of dienes
US10844404B2 (en) 2015-04-09 2020-11-24 Genomatica Inc. Engineered microorgansims and methods for improved crotyl alcohol production
US10941454B2 (en) 2015-05-30 2021-03-09 Genomatica, Inc. Vinylisomerase-dehydratases, alkenol dehydratases, linalool dehydratases and crotyl alcohol dehydratases and methods for making and using them
EP3341471A4 (en) * 2015-08-24 2020-07-22 White Dog Labs, Inc. MICROBIAL ORGANISMS FOR CONVERTING ACETYL-COA IN CROTYL ALCOHOL AND METHOD FOR PRODUCING CROTYL ALCOHOL
SG11201803164SA (en) 2015-10-30 2018-05-30 Genomatica Inc Methanol dehydrogenase fusion proteins
KR101929631B1 (ko) 2016-12-20 2018-12-14 서강대학교산학협력단 미생물 발효를 이용한 1,3-부타디엔의 제조 방법
EA201891926A1 (ru) * 2017-02-03 2019-04-30 Киверди, Инк. Микроорганизмы и искусственные экосистемы для производства белка, продуктов питания и полезных побочных продуктов из субстратов c1
WO2019006257A1 (en) 2017-06-30 2019-01-03 Invista North America .S.A.R.L. METHODS, SYNTHETIC HOSTS AND REAGENTS FOR HYDROCARBON BIOSYNTHESIS
WO2019006255A1 (en) 2017-06-30 2019-01-03 Invista North America S.A.R.L. METHODS, MATERIALS, SYNTHETIC HOSTS AND REAGENTS FOR HYDROCARBON BIOSYNTHESIS AND DERIVATIVES
JP7242058B2 (ja) * 2017-07-24 2023-03-20 国立研究開発法人理化学研究所 デカルボキシラーゼ、及びそれを用いた不飽和炭化水素化合物の製造方法
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
EP3814515A2 (en) 2018-06-26 2021-05-05 Genomatica, Inc. Engineered microorganisms with g3p---> 3pg enzyme and/or fructose-1,6-bisphosphatase including those having synthetic or enhanced methylotrophy
WO2021030835A1 (en) * 2019-08-12 2021-02-18 Zymergen Inc. Engineered biosynthetic pathways for production of 3-amino-4-hydroxybenzoic acid by fermentation
JP7276493B2 (ja) 2019-10-24 2023-05-18 信越化学工業株式会社 熱伝導性シリコーン組成物及びその製造方法
MX2023011547A (es) 2021-04-01 2023-10-30 Synthos Dwory 7 Spolka Z Ograniczona Odpowiedzialnoscia Procedimiento conducido adiabaticamente para la produccion de 1,3-butadieno a partir de mezclas de etanol y acetaldehido.
JP7761892B2 (ja) 2023-06-15 2025-10-29 株式会社Ｃｏ２資源化研究所 クロチルアルコールを生成するヒドロゲノフィラス属細菌形質転換体

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB525198A (en) 1938-03-21 1940-08-23 Melle Usines Sa Improvements in or relating to the preparation of di-olefines
US5219757A (en) 1988-04-27 1993-06-15 Daicel Chemical Industries, Ltd. Production of optically active 1,3-butanediol by asymmetric assimilation or reduction of 4-hydroxy-2-butanone
US5849970A (en) 1995-06-23 1998-12-15 The Regents Of The University Of Colorado Materials and methods for the bacterial production of isoprene
AU3482200A (en) 1999-02-02 2000-08-25 Bernhard Palsson Methods for identifying drug targets based on genomic sequence data
WO2002055995A2 (en) 2001-01-10 2002-07-18 Penn State Res Found Method and system for modeling cellular metabolism
US7127379B2 (en) 2001-01-31 2006-10-24 The Regents Of The University Of California Method for the evolutionary design of biochemical reaction networks
CA2439260C (en) 2001-03-01 2012-10-23 The Regents Of The University Of California Models and methods for determining systemic properties of regulated reaction networks
US20030224363A1 (en) 2002-03-19 2003-12-04 Park Sung M. Compositions and methods for modeling bacillus subtilis metabolism
CA2480216A1 (en) 2002-03-29 2003-10-09 Genomatica, Inc. Human metabolic models and methods
US7856317B2 (en) 2002-06-14 2010-12-21 Genomatica, Inc. Systems and methods for constructing genomic-based phenotypic models
WO2004018621A2 (en) 2002-07-10 2004-03-04 The Penn State Research Foundation Method for determining gene knockout strategies
JP5064656B2 (ja) 2002-10-15 2012-10-31 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 実施反応経路を同定するための方法およびシステム
DE102006025821A1 (de) 2006-06-02 2007-12-06 Degussa Gmbh Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd
EP3800262A1 (en) 2007-03-16 2021-04-07 Genomatica, Inc. Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
EP2706111A1 (en) * 2008-03-03 2014-03-12 Joule Unlimited Technologies, Inc. Engineered CO2 fixing microorganisms producing carbon-based products of interest
EP2279251A2 (en) 2008-04-23 2011-02-02 Danisco US Inc. Isoprene synthase variants for improved microbial production of isoprene
WO2010006076A2 (en) * 2008-07-08 2010-01-14 Opx Biotechnologies Inc. Methods, compositions and systems for biosynthetic bio production of 1,4-butanediol
SG169641A1 (en) 2008-09-15 2011-04-29 Danisco Us Inc Systems using cell culture for production of isoprene
WO2010127319A2 (en) * 2009-04-30 2010-11-04 Genomatica, Inc. Organisms for the production of 1,3-butanediol
US20120276606A1 (en) 2009-10-30 2012-11-01 Daicel Corporation Recombinant microorganisms with 1,3-butanediol-producing function and uses thereof
JP5911847B2 (ja) * 2010-05-05 2016-04-27 ジェノマティカ， インコーポレイテッド ブタジエンの生合成のための微生物および方法
SG191214A1 (en) * 2010-12-17 2013-07-31 Mitsubishi Chem Corp Synthetic pathway generating apparatus, synthesis pathway generating method, synthesis pathway generating program, and method of producing 3-hydroxypropionic acid, crotonyl alcohol and butadiene
BR112013019811A2 (pt) * 2011-02-02 2017-02-21 Genomatica Inc processo para a produção de butadieno e organismo microbiano que não ocorre naturalmente.
US9169486B2 (en) * 2011-06-22 2015-10-27 Genomatica, Inc. Microorganisms for producing butadiene and methods related thereto

Also Published As

Publication number Publication date
WO2012106516A1 (en) 2012-08-09
EP2670852A1 (en) 2013-12-11
MX2013008988A (es) 2014-03-21
CA2826293A1 (en) 2012-08-09
US20170044572A1 (en) 2017-02-16
PH12013501630A1 (en) 2014-01-06
JP2016192974A (ja) 2016-11-17
JP5960729B2 (ja) 2016-08-02
US20120225466A1 (en) 2012-09-06
SG192614A1 (en) 2013-09-30
CN103459602A (zh) 2013-12-18
CN103459602B (zh) 2016-08-10
US20210147881A1 (en) 2021-05-20
MY179664A (en) 2020-11-11
US20190048366A1 (en) 2019-02-14
KR20140145935A (ko) 2014-12-24
US9321701B2 (en) 2016-04-26
BR112013019811A2 (pt) 2017-02-21
JP2014504508A (ja) 2014-02-24
JP2018166514A (ja) 2018-11-01
EP2670852A4 (en) 2017-04-26
CN106191132A (zh) 2016-12-07
AU2012212118B2 (en) 2015-11-12
MY162964A (en) 2017-07-31
AU2012212118A1 (en) 2013-05-02

Similar Documents

Publication Publication Date Title
PH12013501630A1 (en) Microorganisms and methods for the biosynthesis of butadiene
PH12014500588A1 (en) Microorganisms and methods for producing alkenes
MY165107A (en) A fermentation process
WO2012177619A3 (en) Microorganisms for producing 1,3-butanediol and methods related thereto
PH12014500391A1 (en) Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols
MY186108A (en) Gas fermentation for the production of protein or feed
MY175283A (en) Mutant microorganisms having high ability to produce putrescine and method for producing putrescine using the same
MY161621A (en) Methods and systems for the production of hydrocarbon products
AU2012353654A8 (en) Modified microorganisms and methods of making butadiene using same
MY163228A (en) Process for Producing 3-Hydroxybutyric Acid or Salt Thereof
MX355741B (es) Metodos y composiciones de fermentacion microbiana.
MY168208A (en) Recombinant microorganisms and uses therefor
MX348760B (es) Proceso para fermentacion de gas de sintesis.
NZ600866A (en) Alcohol production process
MY171760A (en) Microorganisms and methods for the production of caprolactone
UA106381C2 (ru) Способ получения ферментированного молочного продукта
MY180565A (en) Apparatus and method for separating and refining product manufactured by microbial fermentation by using adsorbent
IN2014DN07980A (OSRAM)
MY163223A (en) Method for producing hydrocarbons
MX2012010427A (es) Cepas de levaduras y sus usos en la produccion de lipidos.
WO2012177983A3 (en) Microorganisms for producing ethylene glycol and methods related thereto
WO2013034613A3 (de) Verfahren zur herstellung eines getränks oder einer getränkebase
MY180152A (en) A fermentation process
WO2014049382A3 (en) Ethylenediamine fermentative production by a recombinant microorganism
EP4389904A3 (en) Microorganisms for producing 4c-5c compounds with unsaturation and methods related thereto

Legal Events

Date Code Title Description
FG Grant or registration