MX348127B - Derivados de quinazolinona como inhibidores del virus de la hepatitis c. - Google Patents

Derivados de quinazolinona como inhibidores del virus de la hepatitis c.

Info

Publication number
MX348127B
MX348127B MX2014008042A MX2014008042A MX348127B MX 348127 B MX348127 B MX 348127B MX 2014008042 A MX2014008042 A MX 2014008042A MX 2014008042 A MX2014008042 A MX 2014008042A MX 348127 B MX348127 B MX 348127B
Authority
MX
Mexico
Prior art keywords
hcv
inhibitors
hcv inhibitors
quinazolinone derivatives
quinazolinone
Prior art date
Application number
MX2014008042A
Other languages
English (en)
Spanish (es)
Other versions
MX2014008042A (es
Inventor
Pierre Jean-Marie Bernard Raboisson
Koen Vandyck
Original Assignee
Janssen Sciences Ireland Uc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Uc filed Critical Janssen Sciences Ireland Uc
Publication of MX2014008042A publication Critical patent/MX2014008042A/es
Publication of MX348127B publication Critical patent/MX348127B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
MX2014008042A 2011-12-28 2012-12-27 Derivados de quinazolinona como inhibidores del virus de la hepatitis c. MX348127B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11195841 2011-12-28
EP12152267 2012-01-24
PCT/EP2012/076942 WO2013098320A1 (en) 2011-12-28 2012-12-27 Quinazolinone derivatives as hcv inhibitors

Publications (2)

Publication Number Publication Date
MX2014008042A MX2014008042A (es) 2014-08-21
MX348127B true MX348127B (es) 2017-05-26

Family

ID=47505013

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014008042A MX348127B (es) 2011-12-28 2012-12-27 Derivados de quinazolinona como inhibidores del virus de la hepatitis c.

Country Status (12)

Country Link
US (1) US9382261B2 (show.php)
EP (1) EP2797913B1 (show.php)
JP (2) JP6199891B2 (show.php)
CN (1) CN104169271B (show.php)
AU (1) AU2012360910B8 (show.php)
BR (1) BR112014016007A8 (show.php)
CA (1) CA2858646A1 (show.php)
ES (1) ES2601461T3 (show.php)
IN (1) IN2014MN01486A (show.php)
MX (1) MX348127B (show.php)
RU (1) RU2014131017A (show.php)
WO (1) WO2013098320A1 (show.php)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9326973B2 (en) 2012-01-13 2016-05-03 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US20150023913A1 (en) 2013-07-02 2015-01-22 Bristol-Myers Squibb Company Hepatitis C Virus Inhibitors
US9717712B2 (en) 2013-07-02 2017-08-01 Bristol-Myers Squibb Company Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus
EP3021845A1 (en) 2013-07-17 2016-05-25 Bristol-Myers Squibb Company Combinations comprising biphenyl derivatives for use in the treatment of hcv
US10617675B2 (en) 2015-08-06 2020-04-14 Bristol-Myers Squibb Company Hepatitis C virus inhibitors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8143288B2 (en) 2005-06-06 2012-03-27 Bristol-Myers Squibb Company Inhibitors of HCV replication
US8329159B2 (en) 2006-08-11 2012-12-11 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US7659270B2 (en) * 2006-08-11 2010-02-09 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
JP2010506843A (ja) 2006-10-13 2010-03-04 エックスティーエル バイオファーマシューティカルズ リミテッド Ｈｃｖを治療するための化合物および方法
US20100055071A1 (en) 2006-11-21 2010-03-04 Martin Robert Leivers Anti-Viral Compounds
US7906655B2 (en) 2008-08-07 2011-03-15 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
JP2012510523A (ja) 2008-12-03 2012-05-10 プレシディオ ファーマシューティカルズ インコーポレイテッド Ｈｃｖｎｓ５ａの阻害剤
HK1203929A1 (en) * 2008-12-03 2015-11-06 普雷西迪奥制药公司 Inhibitors of hcv ns5a
WO2011004276A1 (en) * 2009-07-06 2011-01-13 Pfizer Limited Hepatitis c virus inhibitors
UA108211C2 (uk) 2009-11-04 2015-04-10 Янссен Рід Айрленд Бензімідазолімідазольні похідні
WO2011091446A1 (en) * 2010-01-22 2011-07-28 Glaxosmithkline Llc Chemical compounds
CN102858157A (zh) * 2010-03-04 2013-01-02 埃南塔制药公司 作为hcv复制的抑制剂的组合药物活性剂
US8815849B2 (en) * 2010-07-26 2014-08-26 Janssen R&D Ireland Hetero-bicyclic derivatives as HCV inhibitors
WO2013098313A1 (en) * 2011-12-28 2013-07-04 Janssen R&D Ireland Hetero-bicyclic derivatives as hcv inhibitors

Also Published As

Publication number Publication date
RU2014131017A (ru) 2016-02-20
CN104169271A (zh) 2014-11-26
CN104169271B (zh) 2017-04-05
AU2012360910A8 (en) 2017-02-02
EP2797913B1 (en) 2016-08-17
WO2013098320A1 (en) 2013-07-04
BR112014016007A8 (pt) 2017-07-04
MX2014008042A (es) 2014-08-21
EP2797913A1 (en) 2014-11-05
BR112014016007A2 (pt) 2017-06-13
US9382261B2 (en) 2016-07-05
AU2012360910B8 (en) 2017-02-02
AU2012360910B2 (en) 2017-01-05
AU2012360910A1 (en) 2014-06-26
CA2858646A1 (en) 2013-07-04
IN2014MN01486A (show.php) 2015-04-24
JP2015503537A (ja) 2015-02-02
US20140378485A1 (en) 2014-12-25
ES2601461T3 (es) 2017-02-15
JP6199891B2 (ja) 2017-09-20
JP2018012699A (ja) 2018-01-25

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Legal Events

Date Code Title Description
GB Transfer or assignment

Owner name: JANSSEN SCIENCES IRELAND UC

FG Grant or registration