MX3473E - Procedimiento para la preparacion de una vacuna contra hepatitis viral - Google Patents
Procedimiento para la preparacion de una vacuna contra hepatitis viralInfo
- Publication number
- MX3473E MX3473E MX000071U MX7176U MX3473E MX 3473 E MX3473 E MX 3473E MX 000071 U MX000071 U MX 000071U MX 7176 U MX7176 U MX 7176U MX 3473 E MX3473 E MX 3473E
- Authority
- MX
- Mexico
- Prior art keywords
- serum
- procedure
- antigen
- preparation
- viral hepatitis
- Prior art date
Links
- 206010019799 Hepatitis viral Diseases 0.000 title abstract 2
- 229960002520 hepatitis vaccine Drugs 0.000 title abstract 2
- 201000001862 viral hepatitis Diseases 0.000 title abstract 2
- 210000002966 serum Anatomy 0.000 abstract 6
- 239000000427 antigen Substances 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 abstract 1
- 231100000283 hepatitis Toxicity 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a procedimiento para la preparación de una vacuna contra hepatitis viral caracterizado porque comprende: A. obtener el suero sanguíneo de un portador crónico de hepatitis Be Ag cuyo suero sanguineo contiene HBsAg asociados con partículas de un tamano de 16 a 50 nm de las cuales algunas están en escala de 30 - 50 nm y están sustancialmente libre de anti-HBs y anti-e anticuerpos, con por lo menos 1 por ciento de las partículas esta caracterizado por la presencia de e-antigeno libre, no combinado y no precipitado; B. Separar otra materia proteinácea del suero tal que el suero contiene menos del 10 por ciento de material proteináceo o diferente del asociado con HBsAg o e-antígeno; C. Inactivar cualquier virus en suero; y D. Diluir el suero que contiene antígeno con un medio fisiológicamente aceptable.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7508046A FR2303562A1 (fr) | 1975-03-14 | 1975-03-14 | Nouvelle preparation d'antigene utilisable comme vaccin |
| US05/631,961 US4118479A (en) | 1975-03-14 | 1975-11-17 | Vaccine for active immunization containing hepatitis B surface antigen and associated antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX3473E true MX3473E (es) | 1980-12-10 |
Family
ID=26218778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX000071U MX3473E (es) | 1975-03-14 | 1976-03-12 | Procedimiento para la preparacion de una vacuna contra hepatitis viral |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4118478A (es) |
| JP (1) | JPS51133414A (es) |
| AT (1) | AT349136B (es) |
| AU (1) | AU505999B2 (es) |
| CA (1) | CA1066190A (es) |
| DE (1) | DE2610717C3 (es) |
| MX (1) | MX3473E (es) |
| NL (1) | NL7602621A (es) |
| SE (1) | SE437329B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4102996A (en) * | 1977-04-20 | 1978-07-25 | Merck & Co., Inc. | Method of preparing hepatitis B core antigen |
| DE2750045A1 (de) * | 1977-11-09 | 1979-05-10 | Behringwerke Ag | Verfahren zur entfernung von detergentien aus virusantigensuspensionen |
| ZA792485B (en) * | 1978-06-07 | 1980-06-25 | New York Blood Center Inc | Vaccine for active immunization containing hepatitis b surface and/or e-antigens |
| US4181713A (en) * | 1978-10-30 | 1980-01-01 | Merck & Co., Inc. | Isolation of HBs Ag |
| US4395395A (en) * | 1979-05-21 | 1983-07-26 | The United States Of America As Represented By The Department Of Health And Human Services | Detection of non-A, non-B hepatitis associated antigen |
| JPS5610119A (en) * | 1979-07-05 | 1981-02-02 | Alpha Therapeutic Corp | Manufacture of b type hepatitis infection preventive vaccine |
| JPH0625069B2 (ja) * | 1981-01-29 | 1994-04-06 | ブリティッシュ・テクノロジー・グループ・リミテッド | B型肝炎ワクチン製造方法 |
| DE3150935A1 (de) * | 1981-12-23 | 1983-06-30 | Uwe Dr.med. 3400 Göttingen Böttcher | Verfahren zur herstellung eines hepatitis-b impfstoffes |
| US5324513A (en) * | 1984-03-07 | 1994-06-28 | Institut Pasteur | Composition useful for the fabrication of vaccines |
| US4639371A (en) * | 1984-10-02 | 1987-01-27 | New York Blood Center, Inc. | Hepatitis B antigenic compositions and vaccines against hepatitis B derived therefrom |
| US4683294A (en) * | 1985-04-03 | 1987-07-28 | Smith Kline Rit, S.A. | Process for the extraction and purification of proteins from culture media producing them |
| SG11202003793WA (en) | 2017-10-30 | 2020-05-28 | Baxalta GmbH | Environmentally compatible detergents for inactivation of lipid-enveloped viruses |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4017360A (en) * | 1975-05-14 | 1977-04-12 | Merck & Co., Inc. | Method for purifying hepatitis B antigen |
| US4024243A (en) * | 1975-06-16 | 1977-05-17 | Merck & Co., Inc. | Process for isolating hepatitis B antigen |
-
1976
- 1976-02-27 SE SE7602871A patent/SE437329B/xx not_active IP Right Cessation
- 1976-03-12 NL NL7602621A patent/NL7602621A/xx not_active Application Discontinuation
- 1976-03-12 AU AU11967/76A patent/AU505999B2/en not_active Expired
- 1976-03-12 CA CA248,345A patent/CA1066190A/en not_active Expired
- 1976-03-12 MX MX000071U patent/MX3473E/es unknown
- 1976-03-13 DE DE2610717A patent/DE2610717C3/de not_active Expired
- 1976-03-15 JP JP51028011A patent/JPS51133414A/ja active Pending
- 1976-03-15 AT AT186276A patent/AT349136B/de not_active IP Right Cessation
-
1977
- 1977-02-24 US US05/771,728 patent/US4118478A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA1066190A (en) | 1979-11-13 |
| AT349136B (de) | 1979-03-26 |
| US4118478A (en) | 1978-10-03 |
| DE2610717A1 (de) | 1977-05-26 |
| SE7602871L (sv) | 1976-09-15 |
| DE2610717B2 (de) | 1980-05-14 |
| AU1196776A (en) | 1977-09-15 |
| AU505999B2 (en) | 1979-12-13 |
| ATA186276A (de) | 1978-08-15 |
| DE2610717C3 (de) | 1981-02-05 |
| NL7602621A (nl) | 1976-09-16 |
| SE437329B (sv) | 1985-02-25 |
| JPS51133414A (en) | 1976-11-19 |
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