GB1518582A - Viral hepatitis vaccine - Google Patents
Viral hepatitis vaccineInfo
- Publication number
- GB1518582A GB1518582A GB9299/76A GB929976A GB1518582A GB 1518582 A GB1518582 A GB 1518582A GB 9299/76 A GB9299/76 A GB 9299/76A GB 929976 A GB929976 A GB 929976A GB 1518582 A GB1518582 A GB 1518582A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hepatitis
- vaccine
- surface antigen
- particles
- march
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 206010019799 Hepatitis viral Diseases 0.000 title abstract 2
- 201000001862 viral hepatitis Diseases 0.000 title abstract 2
- 229960002520 hepatitis vaccine Drugs 0.000 title 1
- 208000002672 hepatitis B Diseases 0.000 abstract 5
- 239000000427 antigen Substances 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 239000002245 particle Substances 0.000 abstract 3
- 210000002966 serum Anatomy 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 208000000419 Chronic Hepatitis B Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000007865 diluting Methods 0.000 abstract 1
- SPSXSWRZQFPVTJ-ZQQKUFEYSA-N hepatitis b vaccine Chemical compound C([C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCSC)C(=O)N[C@@H](CC1N=CN=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)OC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](N)CCCNC(N)=N)C1=CC=CC=C1 SPSXSWRZQFPVTJ-ZQQKUFEYSA-N 0.000 abstract 1
- 229940124736 hepatitis-B vaccine Drugs 0.000 abstract 1
- 230000000415 inactivating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
1518582 Hepatitis B vaccine COMMUNITY BLOOD COUNCIL OF GREATER NEW YORK Inc 9 March 1976 [14 March 1975 17 Nov 1975] 09299/76 Heading A5B A vaccine against viral hepatitis comprises antigenic particles of size 30 to 50 nm containing unprecipitated free hepatitis B surface antigen and at least 5% of said particles containing unprecipitated antigens specific to filaments or hepatitis B Dane particles, and having less than 10 units per 1000 units of hepatitis B surface antigen, of hepatitis B surface antigen antibodies, together with a physiologically acceptable medium. The vaccine is prepared from blood serum of chronic hepatitis B carriers, by removing unwanted proteinaceous matter, inactivating virus in the serum, and diluting with a suitable medium.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/631,961 US4118479A (en) | 1975-03-14 | 1975-11-17 | Vaccine for active immunization containing hepatitis B surface antigen and associated antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1518582A true GB1518582A (en) | 1978-07-19 |
Family
ID=24533494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB9299/76A Expired GB1518582A (en) | 1975-11-17 | 1976-03-09 | Viral hepatitis vaccine |
Country Status (3)
| Country | Link |
|---|---|
| FR (1) | FR2331354A2 (en) |
| GB (1) | GB1518582A (en) |
| SU (1) | SU728720A3 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4102996A (en) * | 1977-04-20 | 1978-07-25 | Merck & Co., Inc. | Method of preparing hepatitis B core antigen |
| ZA792485B (en) * | 1978-06-07 | 1980-06-25 | New York Blood Center Inc | Vaccine for active immunization containing hepatitis b surface and/or e-antigens |
-
1976
- 1976-03-09 GB GB9299/76A patent/GB1518582A/en not_active Expired
- 1976-03-12 SU SU762332953A patent/SU728720A3/en active
- 1976-03-30 FR FR7609168A patent/FR2331354A2/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2331354A2 (en) | 1977-06-10 |
| FR2331354B2 (en) | 1979-01-19 |
| SU728720A3 (en) | 1980-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |