ES2062330T3 - Conjugados. - Google Patents
Conjugados.Info
- Publication number
- ES2062330T3 ES2062330T3 ES90301589T ES90301589T ES2062330T3 ES 2062330 T3 ES2062330 T3 ES 2062330T3 ES 90301589 T ES90301589 T ES 90301589T ES 90301589 T ES90301589 T ES 90301589T ES 2062330 T3 ES2062330 T3 ES 2062330T3
- Authority
- ES
- Spain
- Prior art keywords
- hbcag
- lys
- polypeptide
- particles
- conjugates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- -1 AMINO SIDE CHAIN Chemical group 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 abstract 1
- 231100000283 hepatitis Toxicity 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 239000002699 waste material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PARTICULAS (HBCAG) ANTIGENAS DEL NUCLEO DE LA HEPATITIS B, QUE LLEVAN UN POLIPEPTIDO QUE PRESENTA UN EPITOPO ANTIGENICO Y QUE SON ADECUADAS PARA USO EN VACUNAS, SE COMPONE DE HBCAG PROVISTO CON UNA EXTENSION TERMINAL N QUE INCORPORA UN RESIDUO "LYS" Y EL MENCIONADO POLIPEPTIDO SE ACOPLA A LAS PARTICULAS POR MEDIO DEL GRUPO AMINO DE CADENA LATERAL DEL RESIDUO "LYS".
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898903313A GB8903313D0 (en) | 1989-02-14 | 1989-02-14 | Conjugates |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2062330T3 true ES2062330T3 (es) | 1994-12-16 |
Family
ID=10651663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90301589T Expired - Lifetime ES2062330T3 (es) | 1989-02-14 | 1990-02-14 | Conjugados. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0385610B1 (es) |
JP (1) | JP2858848B2 (es) |
AU (1) | AU634518B2 (es) |
CA (1) | CA2009896A1 (es) |
DE (1) | DE69007311T2 (es) |
DK (1) | DK0385610T3 (es) |
ES (1) | ES2062330T3 (es) |
GB (1) | GB8903313D0 (es) |
IE (1) | IE64983B1 (es) |
NZ (1) | NZ232505A (es) |
ZA (1) | ZA901086B (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2167304T3 (es) * | 1987-06-22 | 2002-05-16 | Medeva Holdings Bv | Peptido que contiene el antigeno de superficie de la hepatitis b. |
EP0491077A1 (en) * | 1990-12-19 | 1992-06-24 | Medeva Holdings B.V. | A composition used as a therapeutic agent against chronic viral hepatic diseases |
EP0563091A1 (en) * | 1990-12-20 | 1993-10-06 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Vaccines based on hepatitis b surface antigen |
US5607691A (en) * | 1992-06-12 | 1997-03-04 | Affymax Technologies N.V. | Compositions and methods for enhanced drug delivery |
FR2699538B1 (fr) * | 1992-12-22 | 1995-02-03 | Agronomique Inst Nat Rech | Sous-unité d'une capsule protéique CS31A modifiée par au moins un peptide hétérologue, capsule protéique CS31A et microorganismes portant ces sous-unités; procédés d'obtention et utilisation de ceux-ci. |
AU2540897A (en) * | 1996-03-21 | 1997-10-10 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Methods and compositions of chimeric polypeptides for tumor antigen vaccines |
IL137766A0 (en) * | 1998-02-12 | 2001-10-31 | Immune Complex Corp | Strategically modified hepatitis b core proteins and their derivatives |
EP1123114B1 (en) | 1998-10-21 | 2005-12-28 | THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Virus-like particles for the induction of autoantibodies |
MXPA01005389A (es) | 1998-11-30 | 2003-03-27 | Cytos Biotechnology Ag | Presentacion molecular ordenada de antigenos, metodos de preparacion y uso. |
CZ20011907A3 (cs) | 1998-12-04 | 2002-01-16 | Biogen, Inc. | Částice jádra HBV s imunogenními sloľkami navázanými prostřednictvím peptidových ligandů |
WO2001085208A2 (en) | 2000-05-05 | 2001-11-15 | Cytos Biotechnology Ag | Molecular antigen arrays and vaccines |
US7320793B2 (en) | 2001-01-19 | 2008-01-22 | Cytos Biotechnology Ag | Molecular antigen array |
US7128911B2 (en) | 2001-01-19 | 2006-10-31 | Cytos Biotechnology Ag | Antigen arrays for treatment of bone disease |
US7094409B2 (en) | 2001-01-19 | 2006-08-22 | Cytos Biotechnology Ag | Antigen arrays for treatment of allergic eosinophilic diseases |
US7115266B2 (en) | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
CN102061288A (zh) | 2002-07-17 | 2011-05-18 | 希托斯生物技术股份公司 | 使用衍生自ap205外壳蛋白的病毒样颗粒的分子抗原阵列 |
BR0312297A (pt) | 2002-07-18 | 2005-04-12 | Cytos Biotechnology Ag | Conjugados veìculos de hapteno e seu uso |
SI1524994T1 (sl) | 2002-07-19 | 2011-08-31 | Cytos Biotechnology Ag | Sestavki cepiv, ki vsebujejo amiloidne beta 1-6 antigenske mreĹľe |
US7537767B2 (en) | 2003-03-26 | 2009-05-26 | Cytis Biotechnology Ag | Melan-A- carrier conjugates |
AU2004224762B2 (en) | 2003-03-26 | 2009-12-24 | Kuros Us Llc | Packaging of immunostimulatory oligonucleotides into virus-like particles: method of preparation and use |
US8080642B2 (en) | 2003-05-16 | 2011-12-20 | Vical Incorporated | Severe acute respiratory syndrome DNA compositions and methods of use |
US20060024670A1 (en) | 2004-05-18 | 2006-02-02 | Luke Catherine J | Influenza virus vaccine composition and methods of use |
GB0424563D0 (en) | 2004-11-05 | 2004-12-08 | Novartis Ag | Organic compounds |
ES2932952T3 (es) | 2012-04-24 | 2023-01-30 | Ohio State Innovation Foundation | Composiciones y métodos para tratar y prevenir el síndrome reproductivo y respiratorio porcino |
US10279028B2 (en) | 2012-04-24 | 2019-05-07 | Ohio State Innovation Foundation | Compositions and methods for treating and preventing porcine reproductive and respiratory syndrome |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8421282D0 (en) * | 1984-08-22 | 1984-09-26 | Connaught Lab | Multispecific antigenic proteins |
US4882145A (en) * | 1986-12-09 | 1989-11-21 | Scripps Clinic And Research Foundation | T cell epitopes of the hepatitis B virus nucleocapsid protein |
GB8709274D0 (en) * | 1987-04-16 | 1987-05-20 | Wellcome Found | Peptides |
-
1989
- 1989-02-14 GB GB898903313A patent/GB8903313D0/en active Pending
-
1990
- 1990-02-13 ZA ZA901086A patent/ZA901086B/xx unknown
- 1990-02-13 CA CA002009896A patent/CA2009896A1/en not_active Abandoned
- 1990-02-13 IE IE50290A patent/IE64983B1/en not_active IP Right Cessation
- 1990-02-13 NZ NZ232505A patent/NZ232505A/en unknown
- 1990-02-14 JP JP2033622A patent/JP2858848B2/ja not_active Expired - Fee Related
- 1990-02-14 ES ES90301589T patent/ES2062330T3/es not_active Expired - Lifetime
- 1990-02-14 DE DE69007311T patent/DE69007311T2/de not_active Expired - Lifetime
- 1990-02-14 AU AU49755/90A patent/AU634518B2/en not_active Ceased
- 1990-02-14 EP EP90301589A patent/EP0385610B1/en not_active Expired - Lifetime
- 1990-02-14 DK DK90301589.9T patent/DK0385610T3/da active
Also Published As
Publication number | Publication date |
---|---|
EP0385610A1 (en) | 1990-09-05 |
AU4975590A (en) | 1990-10-18 |
CA2009896A1 (en) | 1990-08-14 |
ZA901086B (en) | 1990-11-28 |
IE900502L (en) | 1990-08-14 |
IE64983B1 (en) | 1995-09-20 |
DE69007311D1 (de) | 1994-04-21 |
EP0385610B1 (en) | 1994-03-16 |
DK0385610T3 (da) | 1994-07-25 |
NZ232505A (en) | 1992-12-23 |
JPH0327400A (ja) | 1991-02-05 |
JP2858848B2 (ja) | 1999-02-17 |
DE69007311T2 (de) | 1994-06-23 |
AU634518B2 (en) | 1993-02-25 |
GB8903313D0 (en) | 1989-04-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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