MX347355B - Diagnostico basado en troponina y en peptido natriuretico cerebral (bnp) de pacientes en riesgo y de causa de ataque. - Google Patents
Diagnostico basado en troponina y en peptido natriuretico cerebral (bnp) de pacientes en riesgo y de causa de ataque.Info
- Publication number
- MX347355B MX347355B MX2014003496A MX2014003496A MX347355B MX 347355 B MX347355 B MX 347355B MX 2014003496 A MX2014003496 A MX 2014003496A MX 2014003496 A MX2014003496 A MX 2014003496A MX 347355 B MX347355 B MX 347355B
- Authority
- MX
- Mexico
- Prior art keywords
- stroke
- troponin
- cause
- risk patients
- based diagnosis
- Prior art date
Links
- 238000003745 diagnosis Methods 0.000 title 1
- 208000032382 Ischaemic stroke Diseases 0.000 abstract 2
- 206010014498 Embolic stroke Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/326—Arrhythmias, e.g. ventricular fibrillation, tachycardia, atrioventricular block, torsade de pointes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
La presente invención se refiere a un método para diferenciar de manera temprana sí un sujeto padece de ataque insquémico cardioembólico o de ataque isquémico no cardioembólico, caracterizado porque comprende determinar la cantidad de una troponina cardíaca en una muestra de un sujeto que padece de ataque isquémico, en donde la muestra ser ha obtenido no más de 6 horas después del comienzo de los síntomas del ataque isquémico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11185421 | 2011-10-17 | ||
| PCT/EP2012/070553 WO2013057135A1 (en) | 2011-10-17 | 2012-10-17 | Troponin and bnp based diagnosis of risk patients and cause of stroke |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014003496A MX2014003496A (es) | 2014-07-14 |
| MX347355B true MX347355B (es) | 2017-04-24 |
Family
ID=47049159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014003496A MX347355B (es) | 2011-10-17 | 2012-10-17 | Diagnostico basado en troponina y en peptido natriuretico cerebral (bnp) de pacientes en riesgo y de causa de ataque. |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US20140220604A1 (es) |
| EP (2) | EP3088900B1 (es) |
| JP (2) | JP6117805B2 (es) |
| KR (2) | KR101950561B1 (es) |
| CN (2) | CN105785053B (es) |
| AU (1) | AU2012324967B2 (es) |
| BR (2) | BR122021026652B1 (es) |
| CA (1) | CA2846285C (es) |
| ES (2) | ES2595028T3 (es) |
| MX (1) | MX347355B (es) |
| SG (1) | SG2014014559A (es) |
| WO (1) | WO2013057135A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014072500A1 (en) | 2012-11-09 | 2014-05-15 | Roche Diagnostics Gmbh | Tnt based diagnosis of paroxysmal atrial fibrillation |
| WO2017051938A1 (ko) * | 2015-09-23 | 2017-03-30 | (주)바이오메트릭스 테크놀로지 | 심질환 바이오마커의 표준농도-감도 테이블에 의한 심질환의 진행상태 및 치료상태를 모니터링하는 방법 및 이를 위한 바이오칩 |
| EP3359968B1 (en) | 2015-10-05 | 2020-08-19 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Development and parameter assessment for vertically aligned platinum wire aptasensor arrays for impedimetric detection of cardiac biomarkers |
| ES2817087T3 (es) * | 2016-08-04 | 2021-04-06 | Hoffmann La Roche | ESM-1 (endocan) circulante en la evaluación de la fibrilación auricular |
| WO2018229051A1 (en) * | 2017-06-13 | 2018-12-20 | Roche Diagnostics Gmbh | Fatty acid binding protein 3 for the assessment of atrial fibrillation (af) |
| KR102170826B1 (ko) * | 2018-01-18 | 2020-10-27 | 사회복지법인 삼성생명공익재단 | 뇌졸중 진단 또는 예후예측용 바이오마커 및 이의 용도 |
| JP7451499B2 (ja) * | 2018-08-24 | 2024-03-18 | エフ. ホフマン-ラ ロシュ アーゲー | 心房細動の判定および脳卒中の予測のための循環fgfbp-1(線維芽細胞成長因子結合タンパク質1) |
| CN114807356B (zh) * | 2022-05-19 | 2025-02-28 | 苏州大学 | 一种nppb基因dna羟甲基化标志物、引物及其应用 |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| GB9211686D0 (en) | 1992-06-03 | 1992-07-15 | Medisinsk Innovation A S | Chemical compounds |
| WO1996037777A1 (en) * | 1995-05-23 | 1996-11-28 | Nelson Randall W | Mass spectrometric immunoassay |
| WO1999006445A1 (en) | 1997-07-31 | 1999-02-11 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-15 |
| DE19828466A1 (de) | 1998-06-26 | 1999-12-30 | Roche Diagnostics Gmbh | Entstörung von Immunoassays durch Substanzen, die aus den Framework-Regionen von Antikörpern abgeleitet sind |
| US6709855B1 (en) | 1998-12-18 | 2004-03-23 | Scios, Inc. | Methods for detection and use of differentially expressed genes in disease states |
| DE19902601A1 (de) | 1999-01-23 | 2000-07-27 | Roche Diagnostics Gmbh | Verfahren und Vorrichtung zum Entnehmen analytischer Verbrauchsmittel aus einem Vorratsbehältnis |
| ES2275513T3 (es) | 1999-05-17 | 2007-06-16 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Und Zum Vertrieb Von Pharmaka Mbh | Propiedades neuroprotectoras de gdf-15, un miembro de la superfamilia de tgf-beta. |
| US7427490B2 (en) | 2001-08-20 | 2008-09-23 | Biosite Incorporated | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
| US7632647B2 (en) | 2001-04-13 | 2009-12-15 | Biosite Incorporated | Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes |
| EP1322957B1 (en) | 2001-05-04 | 2009-08-12 | Biosite Incorporated | Diagnostic markers of acute coronary syndromes and methods of use thereof |
| US20030022870A1 (en) * | 2001-06-01 | 2003-01-30 | Victor Dzau | Methods of treating cardiac disorders |
| US7262017B2 (en) * | 2001-09-14 | 2007-08-28 | Torrey Pines Institute For Molecular Studies | Diagnostic markers for ischemia |
| US20030082153A1 (en) * | 2001-10-22 | 2003-05-01 | The Government Of The United States Of America | Stem cells that transform to beating cardiomyocytes |
| US7157235B2 (en) | 2002-06-17 | 2007-01-02 | St. Vincent's Hospital Sydney Limited | Methods of diagnosis, prognosis and treatment of cardiovascular disease |
| CA2511501A1 (en) | 2002-12-24 | 2004-07-15 | Biosite Incorporated | Markers for differential diagnosis and methods of use thereof |
| DE602005008497D1 (de) | 2004-03-15 | 2008-09-11 | Roche Diagnostics Gmbh | Verwendung des BNP-Art und ANP-Art Peptiden für das Festsetzen der Gefahren von Herzgefäß- Komplikationen als Folge der Volumenüberlastung |
| WO2005103720A1 (en) * | 2004-03-29 | 2005-11-03 | Medstar Research Institute, Inc. | Methods of diagnosing cardiovascular disease |
| DE102004023402A1 (de) * | 2004-05-12 | 2005-12-08 | Roche Diagnostics Gmbh | Verfahren zur Erhöhung des dynamischen Messbereichs von auf spezifischen Bindereaktionen basierenden, insbesondere immunologischen Testelementen |
| US20090042780A1 (en) | 2004-05-20 | 2009-02-12 | Acceleron Pharma Inc | Modified TGF-Beta Superfamily Polypeptides and Related Methods |
| US20060003338A1 (en) | 2004-06-30 | 2006-01-05 | Deng David X | System and methods for the management and treatment of vascular graft disease |
| US20060166303A1 (en) * | 2005-01-24 | 2006-07-27 | Eberhard Spanuth | Use of cardiac hormones for assessing a cardiovascular risk with respect to the administration of anti-inflammatory drugs |
| CN101120256A (zh) | 2005-02-17 | 2008-02-06 | 霍夫曼-拉罗奇有限公司 | Nt-原anp/nt-原bnp的比值用于诊断心功能障碍的用途 |
| EP1731910A1 (en) | 2005-06-07 | 2006-12-13 | F. Hoffmann-La Roche Ag | Use of NT-proANP and NT-proBNP for diagnosing cardiac diseases |
| ES2273599B1 (es) * | 2005-10-14 | 2008-06-01 | Universidad De Barcelona | Compuestos para el tratamiento de la fibrilacion auricular. |
| EP1816477A1 (en) | 2006-02-06 | 2007-08-08 | F. Hoffmann-la Roche AG | The use of natriuretic peptides and placenta growth factor levels for risk stratification of individuals elected for cardiac stress testing |
| US7838250B1 (en) * | 2006-04-04 | 2010-11-23 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
| JP5496658B2 (ja) * | 2006-05-25 | 2014-05-21 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 脳卒中を処置する方法 |
| EP1862805A1 (en) | 2006-06-01 | 2007-12-05 | University of Zürich | The use of mrp 8/14 levels for discrimination of individuals at risk of acute coronary syndromes |
| CN106018820B (zh) | 2006-08-04 | 2018-04-27 | 汉诺威医学院 | 根据gdf-15评价心脏介入风险的工具与方法 |
| US8324162B2 (en) * | 2006-08-08 | 2012-12-04 | Mayo Foundation For Medical Education And Research | Diuretic and natriuretic polypeptides lacking the blood pressure lowering property |
| US20080050749A1 (en) * | 2006-08-17 | 2008-02-28 | Ildiko Amann-Zalan | Use of bnp-type peptides for the stratification of therapy with erythropoietic stimulating agents |
| KR20150113216A (ko) | 2006-12-05 | 2015-10-07 | 디코드 제네틱스 이에이치에프 | 심장성 부정맥의 위험 관리를 위한 유전적 마커 |
| IS8576A (is) * | 2006-12-05 | 2007-01-15 | Decode Genetics | Genetic susceptibility variants of atrial fibrillation and stroke |
| WO2008089994A1 (en) | 2007-01-25 | 2008-07-31 | Roche Diagnostics Gmbh | Use of igfbp-7 in the assessment of heart failure |
| US20100197518A1 (en) * | 2007-05-01 | 2010-08-05 | Huichun Xu | Methods for Diagnosing Ischemia |
| EP2037278A1 (en) * | 2007-09-11 | 2009-03-18 | F.Hoffmann-La Roche Ag | Vascular markers in the remodelling of cardiac injury |
| EP2040072B1 (de) * | 2007-09-22 | 2013-01-02 | Roche Diagnostics GmbH | Analysesystem zur Bestimmung der Konzentration eines Analyten in einer Körperflüssigkeit |
| EP2201383B1 (en) | 2007-10-10 | 2014-01-15 | Roche Diagnostics GmbH | Means and methods for monitoring myocardial infarction and its treatment |
| EP2210111A1 (en) * | 2007-10-10 | 2010-07-28 | Roche Diagnostics GmbH | Natriuretic peptide/troponin ratio for the assessment of preexisting myocardial dysfunction in patients with acute coronary syndrome |
| US20090233312A1 (en) * | 2007-10-10 | 2009-09-17 | Nanosphere, Inc. | Methods and assays to assess cardiac risk and ischemia |
| RU2010133157A (ru) * | 2008-01-07 | 2012-02-20 | Орто-Клиникал Дайэгностикс, Инк. (Us) | Определение комплекса sflt-1:ангиогенный фактор |
| EP2318844A1 (en) | 2008-07-14 | 2011-05-11 | Roche Diagnostics GmbH | Multimarker panel for diagnosing, monitoring and selecting the therapy for patients with heart failure |
| WO2010017972A1 (en) * | 2008-08-13 | 2010-02-18 | Roche Diagnostics Gmbh | D-dimer, troponin, nt-probnp for pulmonary embolism |
| JP5902479B2 (ja) * | 2008-10-24 | 2016-04-13 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | マーカーペプチドのレベルを決定することによる脳卒中患者における予後判定及びリスク評価のための方法 |
| EP2425245B1 (en) | 2009-04-27 | 2016-10-05 | Roche Diagnostics GmbH | Use of endostatin as a marker of heart failure |
| CN105548563B (zh) | 2009-07-27 | 2017-09-22 | 霍夫曼-拉罗奇有限公司 | mimecan在评价心力衰竭中的用途 |
| EP2796874B1 (en) | 2010-08-26 | 2017-03-08 | Roche Diagnostics GmbH | Use of biomarkers in monitoring a medication in a subject suffering from heart failure |
| ES2913539T3 (es) | 2012-09-12 | 2022-06-02 | Hoffmann La Roche | Identificación de pacientes con fracción de acortamiento anómala |
| EP2730923A1 (en) | 2012-11-09 | 2014-05-14 | Roche Diagniostics GmbH | NTproBNP and cTnT based therapy guidance in heart failure |
| CN108956999A (zh) | 2012-12-04 | 2018-12-07 | 霍夫曼-拉罗奇有限公司 | 心力衰竭疗法的选择中的生物标记物 |
-
2012
- 2012-10-17 MX MX2014003496A patent/MX347355B/es active IP Right Grant
- 2012-10-17 EP EP16175468.4A patent/EP3088900B1/en not_active Revoked
- 2012-10-17 AU AU2012324967A patent/AU2012324967B2/en active Active
- 2012-10-17 BR BR122021026652-2A patent/BR122021026652B1/pt active IP Right Grant
- 2012-10-17 CA CA2846285A patent/CA2846285C/en active Active
- 2012-10-17 KR KR1020167019896A patent/KR101950561B1/ko active Active
- 2012-10-17 WO PCT/EP2012/070553 patent/WO2013057135A1/en not_active Ceased
- 2012-10-17 JP JP2014536214A patent/JP6117805B2/ja active Active
- 2012-10-17 BR BR112014007007-5A patent/BR112014007007B1/pt active IP Right Grant
- 2012-10-17 SG SG2014014559A patent/SG2014014559A/en unknown
- 2012-10-17 ES ES12775484.4T patent/ES2595028T3/es active Active
- 2012-10-17 ES ES16175468T patent/ES2824110T3/es active Active
- 2012-10-17 CN CN201610329765.9A patent/CN105785053B/zh active Active
- 2012-10-17 KR KR1020147010178A patent/KR101643147B1/ko active Active
- 2012-10-17 CN CN201280062128.XA patent/CN103998938B/zh active Active
- 2012-10-17 EP EP12775484.4A patent/EP2769227B1/en active Active
-
2014
- 2014-04-14 US US14/251,803 patent/US20140220604A1/en not_active Abandoned
-
2015
- 2015-09-21 US US14/859,616 patent/US20160011210A1/en not_active Abandoned
-
2016
- 2016-10-05 US US15/285,798 patent/US20170023588A1/en not_active Abandoned
- 2016-11-04 JP JP2016216261A patent/JP6412085B2/ja active Active
-
2018
- 2018-03-05 US US15/911,695 patent/US11047865B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX347355B (es) | Diagnostico basado en troponina y en peptido natriuretico cerebral (bnp) de pacientes en riesgo y de causa de ataque. | |
| EA201391187A1 (ru) | Способ диагностики злокачественной опухоли и набор для диагностики путем измерения активности nk-клеток | |
| PL2986735T3 (pl) | Sposób określania składu ilościowego komórek krwi w próbce | |
| ECSP14010817A (es) | Composición y método para el diagnóstico y el tratamiento de las enfermedades asociadas a la degeneración de las neuritas | |
| MX2018008882A (es) | Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro. | |
| IN2014CN04326A (es) | ||
| WO2011092285A3 (en) | Means and methods for diagnosing heart failure in a subject | |
| WO2013033609A3 (en) | Methods and compositions for the treatment and diagnosis of cancer | |
| EA201590247A1 (ru) | Антитела к siglec-15 | |
| MX358541B (es) | Metodos para predecir el riesgo de desarrollar hipertension. | |
| IN2015DN00678A (es) | ||
| EP4060048A3 (en) | Non-invasive diagnostic method for diagnosing bladder cancer | |
| MX360479B (es) | Anticuerpos contra microbioma, factores de estres y marcadores de mastocitos como marcadores de diagnostico para ibs. | |
| WO2012094550A3 (en) | Assays and methods of treatment relating to vitamin d insufficiency | |
| MX2015008436A (es) | Composiciones para permeabilizar celulas sanguineos fijos y sus usos. | |
| EA201300817A1 (ru) | Способ улучшенного приживления гемопоэтических стволовых клеток | |
| NZ711543A (en) | Anti-cd83 antibodies and use thereof | |
| FI20115670A0 (fi) | Kardiovaskulaarinen in vitro-malli | |
| NZ729773A (en) | Biomarkers for disease progression in melanoma | |
| EP3489365A4 (en) | COMPOSITION FOR PREDICTING THE RISK OR DIAGNOSING A METABOLIC SYNDROME OR DISORDERS ASSOCIATED WITH METABOLIC SYNDROME USING AN ORAL BACTERIAL COMMUNITY | |
| WO2014179737A3 (en) | Assays and methods of treatment relating to vitamin d insufficiency | |
| EP2571504A4 (en) | Use of aromatase inhibitors for synchronizing ovulation, inducing superovulation or double ovulation and improving twinning and fertility in a mammal | |
| WO2014047442A3 (en) | Biomarkers for assessing treatment of sialic acid deficiency diseases and conditions | |
| WO2011085176A3 (en) | Fret-based method for the determination of protein phosphatase and kinase activity | |
| WO2011163639A3 (en) | Cell aging as a unique biomarker of major depression |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |