MX347355B - Diagnostico basado en troponina y en peptido natriuretico cerebral (bnp) de pacientes en riesgo y de causa de ataque. - Google Patents
Diagnostico basado en troponina y en peptido natriuretico cerebral (bnp) de pacientes en riesgo y de causa de ataque.Info
- Publication number
- MX347355B MX347355B MX2014003496A MX2014003496A MX347355B MX 347355 B MX347355 B MX 347355B MX 2014003496 A MX2014003496 A MX 2014003496A MX 2014003496 A MX2014003496 A MX 2014003496A MX 347355 B MX347355 B MX 347355B
- Authority
- MX
- Mexico
- Prior art keywords
- stroke
- troponin
- cause
- risk patients
- based diagnosis
- Prior art date
Links
- 238000003745 diagnosis Methods 0.000 title 1
- 208000032382 Ischaemic stroke Diseases 0.000 abstract 2
- 206010014498 Embolic stroke Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/326—Arrhythmias, e.g. ventricular fibrillation, tachycardia, atrioventricular block, torsade de pointes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
La presente invención se refiere a un método para diferenciar de manera temprana sí un sujeto padece de ataque insquémico cardioembólico o de ataque isquémico no cardioembólico, caracterizado porque comprende determinar la cantidad de una troponina cardíaca en una muestra de un sujeto que padece de ataque isquémico, en donde la muestra ser ha obtenido no más de 6 horas después del comienzo de los síntomas del ataque isquémico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11185421 | 2011-10-17 | ||
| PCT/EP2012/070553 WO2013057135A1 (en) | 2011-10-17 | 2012-10-17 | Troponin and bnp based diagnosis of risk patients and cause of stroke |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014003496A MX2014003496A (es) | 2014-07-14 |
| MX347355B true MX347355B (es) | 2017-04-24 |
Family
ID=47049159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014003496A MX347355B (es) | 2011-10-17 | 2012-10-17 | Diagnostico basado en troponina y en peptido natriuretico cerebral (bnp) de pacientes en riesgo y de causa de ataque. |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US20140220604A1 (es) |
| EP (2) | EP2769227B1 (es) |
| JP (2) | JP6117805B2 (es) |
| KR (2) | KR101643147B1 (es) |
| CN (2) | CN103998938B (es) |
| AU (1) | AU2012324967B2 (es) |
| BR (2) | BR112014007007B1 (es) |
| CA (1) | CA2846285C (es) |
| ES (2) | ES2595028T3 (es) |
| MX (1) | MX347355B (es) |
| SG (1) | SG2014014559A (es) |
| WO (1) | WO2013057135A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104769436B (zh) | 2012-11-09 | 2018-01-26 | 霍夫曼-拉罗奇有限公司 | 阵发性心房纤颤的基于TnT的诊断 |
| WO2017051938A1 (ko) * | 2015-09-23 | 2017-03-30 | (주)바이오메트릭스 테크놀로지 | 심질환 바이오마커의 표준농도-감도 테이블에 의한 심질환의 진행상태 및 치료상태를 모니터링하는 방법 및 이를 위한 바이오칩 |
| JP7085471B2 (ja) | 2015-10-05 | 2022-06-16 | ユニバーシティ オブ ピッツバーグ-オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション | 心臓バイオマーカーのインピーダンス測定による検出のための垂直配向のプラチナワイヤ・アプタセンサアレイの作成およびパラメータ評価 |
| ES2817087T3 (es) * | 2016-08-04 | 2021-04-06 | Hoffmann La Roche | ESM-1 (endocan) circulante en la evaluación de la fibrilación auricular |
| JP7109484B2 (ja) * | 2017-06-13 | 2022-07-29 | エフ.ホフマン-ラ ロシュ アーゲー | 心房細動(af)の評価のための脂肪酸結合タンパク質3 |
| KR102170826B1 (ko) * | 2018-01-18 | 2020-10-27 | 사회복지법인 삼성생명공익재단 | 뇌졸중 진단 또는 예후예측용 바이오마커 및 이의 용도 |
| EP3841382A1 (en) * | 2018-08-24 | 2021-06-30 | Roche Diagnostics GmbH | Circulating fgfbp-1 (fibroblast growth factor-binding protein 1) in the assessment of atrial fibrillation and for the prediction of stroke |
| CN114807356B (zh) * | 2022-05-19 | 2025-02-28 | 苏州大学 | 一种nppb基因dna羟甲基化标志物、引物及其应用 |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| GB9211686D0 (en) | 1992-06-03 | 1992-07-15 | Medisinsk Innovation A S | Chemical compounds |
| WO1996037777A1 (en) * | 1995-05-23 | 1996-11-28 | Nelson Randall W | Mass spectrometric immunoassay |
| WO1999006445A1 (en) | 1997-07-31 | 1999-02-11 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-15 |
| DE19828466A1 (de) | 1998-06-26 | 1999-12-30 | Roche Diagnostics Gmbh | Entstörung von Immunoassays durch Substanzen, die aus den Framework-Regionen von Antikörpern abgeleitet sind |
| US6709855B1 (en) | 1998-12-18 | 2004-03-23 | Scios, Inc. | Methods for detection and use of differentially expressed genes in disease states |
| DE19902601A1 (de) | 1999-01-23 | 2000-07-27 | Roche Diagnostics Gmbh | Verfahren und Vorrichtung zum Entnehmen analytischer Verbrauchsmittel aus einem Vorratsbehältnis |
| JP2002543841A (ja) | 1999-05-17 | 2002-12-24 | バイオファーム ゲゼルシャフト ツア バイオテクノロジシェン エントヴィックルング ウント ツム フェルトリーブ フォン ファルマカ エムベーハー | TGF−βスーパーファミリーの新規のメンバーであるGDF―15の神経保護特性 |
| US7632647B2 (en) | 2001-04-13 | 2009-12-15 | Biosite Incorporated | Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes |
| EP1322957B1 (en) | 2001-05-04 | 2009-08-12 | Biosite Incorporated | Diagnostic markers of acute coronary syndromes and methods of use thereof |
| WO2002098432A1 (en) | 2001-06-01 | 2002-12-12 | The Brigham And Women's Hospital, Inc. | Methods of treating cardiac disorders |
| DE60233949D1 (de) | 2001-08-20 | 2009-11-19 | Biosite Inc | Diagnostische marker für schlaganfall und hirntrauma sowie verfahren zur verwendung davon |
| US7262017B2 (en) * | 2001-09-14 | 2007-08-28 | Torrey Pines Institute For Molecular Studies | Diagnostic markers for ischemia |
| US20030082153A1 (en) | 2001-10-22 | 2003-05-01 | The Government Of The United States Of America | Stem cells that transform to beating cardiomyocytes |
| CA2390820A1 (en) | 2002-06-17 | 2003-12-17 | St. Vincent's Hospital Sydney Limited | Methods of diagnosis, prognosis and treatment of cardiovascular disease |
| JP2006526140A (ja) | 2002-12-24 | 2006-11-16 | バイオサイト インコーポレイテッド | 鑑別診断のためのマーカーおよびその使用方法 |
| ATE403157T1 (de) | 2004-03-15 | 2008-08-15 | Hoffmann La Roche | Verwendung des bnp-art und anp-art peptiden für das festsetzen der gefahren von herzgefäss- komplikationen als folge der volumenüberlastung |
| US20060099608A1 (en) | 2004-03-29 | 2006-05-11 | Medstar Research Institute | Methods of diagnosing cardiovascular disease |
| DE102004023402A1 (de) * | 2004-05-12 | 2005-12-08 | Roche Diagnostics Gmbh | Verfahren zur Erhöhung des dynamischen Messbereichs von auf spezifischen Bindereaktionen basierenden, insbesondere immunologischen Testelementen |
| WO2005113585A2 (en) | 2004-05-20 | 2005-12-01 | Acceleron Pharma Inc. | Modified tgf-beta superfamily polypeptides |
| US20060003338A1 (en) | 2004-06-30 | 2006-01-05 | Deng David X | System and methods for the management and treatment of vascular graft disease |
| US20060166303A1 (en) * | 2005-01-24 | 2006-07-27 | Eberhard Spanuth | Use of cardiac hormones for assessing a cardiovascular risk with respect to the administration of anti-inflammatory drugs |
| JP4828550B2 (ja) | 2005-02-17 | 2011-11-30 | エフ.ホフマン−ラ ロシュ アーゲー | 心機能障害を診断するためのNT−proANP/NT−proBNP比の使用 |
| EP1731910A1 (en) | 2005-06-07 | 2006-12-13 | F. Hoffmann-La Roche Ag | Use of NT-proANP and NT-proBNP for diagnosing cardiac diseases |
| ES2273599B1 (es) * | 2005-10-14 | 2008-06-01 | Universidad De Barcelona | Compuestos para el tratamiento de la fibrilacion auricular. |
| EP1816477A1 (en) | 2006-02-06 | 2007-08-08 | F. Hoffmann-la Roche AG | The use of natriuretic peptides and placenta growth factor levels for risk stratification of individuals elected for cardiac stress testing |
| US7838250B1 (en) * | 2006-04-04 | 2010-11-23 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
| PL2034830T3 (pl) * | 2006-05-25 | 2015-04-30 | Biogen Ma Inc | Przeciwciało anty-VLA-1 do leczenia udaru |
| EP1862805A1 (en) | 2006-06-01 | 2007-12-05 | University of Zürich | The use of mrp 8/14 levels for discrimination of individuals at risk of acute coronary syndromes |
| MX2009000914A (es) | 2006-08-04 | 2009-06-18 | Hannover Med Hochschule | Medios y metodos para evaluar el riesgo de intervenciones cardiacas basadas en el factor 15 de diferenciacion del crecimiento. |
| CN101501067B (zh) * | 2006-08-08 | 2013-01-16 | 梅约医学教育与研究基金会 | 利尿和利尿钠的多肽 |
| US20080050749A1 (en) * | 2006-08-17 | 2008-02-28 | Ildiko Amann-Zalan | Use of bnp-type peptides for the stratification of therapy with erythropoietic stimulating agents |
| IS8576A (is) * | 2006-12-05 | 2007-01-15 | Decode Genetics | Genetic susceptibility variants of atrial fibrillation and stroke |
| NZ577805A (en) | 2006-12-05 | 2012-09-28 | Decode Genetics Ehf | Genetic markers for risk management of cardiac arrhythmia |
| CN106908603B (zh) | 2007-01-25 | 2019-04-02 | 霍夫曼-拉罗奇有限公司 | Igfbp-7在心力衰竭评估中的用途 |
| CA2685382C (en) * | 2007-05-01 | 2023-02-21 | The Regents Of The University Of California | Methods for diagnosing ischemia |
| EP2037278A1 (en) * | 2007-09-11 | 2009-03-18 | F.Hoffmann-La Roche Ag | Vascular markers in the remodelling of cardiac injury |
| PL2040072T3 (pl) * | 2007-09-22 | 2013-06-28 | Hoffmann La Roche | System analityczny do określania koncentracji analitu w płynie ustrojowym |
| US20090233312A1 (en) * | 2007-10-10 | 2009-09-17 | Nanosphere, Inc. | Methods and assays to assess cardiac risk and ischemia |
| JP2011501113A (ja) * | 2007-10-10 | 2011-01-06 | エフ.ホフマン−ラ ロシュ アーゲー | 急性冠症候群を有する患者での既存の心筋機能不全の評価のためのナトリウム利尿ペプチド/トロポニン比 |
| EP2201383B1 (en) | 2007-10-10 | 2014-01-15 | Roche Diagnostics GmbH | Means and methods for monitoring myocardial infarction and its treatment |
| CA2711071A1 (en) * | 2008-01-07 | 2009-07-16 | Ortho-Clinical Diagnostics, Inc. | Determination of sflt-1:angiogenic factor complex |
| JP2011528115A (ja) | 2008-07-14 | 2011-11-10 | エフ.ホフマン−ラ ロシュ アーゲー | 心不全を有する患者の診断、モニター及び治療の選択のためのマルチマーカーパネル |
| WO2010017972A1 (en) * | 2008-08-13 | 2010-02-18 | Roche Diagnostics Gmbh | D-dimer, troponin, nt-probnp for pulmonary embolism |
| CN102257386B (zh) * | 2008-10-24 | 2014-12-31 | B.R.A.H.M.S有限公司 | 通过测定标志肽的水平在已患过中风或短暂性缺血性发作的患者中进行预后和风险评估 |
| CN102422157B (zh) | 2009-04-27 | 2014-10-29 | 霍夫曼-拉罗奇有限公司 | 内皮抑制素作为心力衰竭标记的应用 |
| CN102549436A (zh) | 2009-07-27 | 2012-07-04 | 霍夫曼-拉罗奇有限公司 | mimecan在评价心力衰竭中的用途 |
| CN108387744A (zh) | 2010-08-26 | 2018-08-10 | 弗·哈夫曼-拉罗切有限公司 | 生物标志物在评估从动脉高血压向心力衰竭的早期转变中的用途 |
| CN104620111B (zh) | 2012-09-12 | 2017-08-08 | 霍夫曼-拉罗奇有限公司 | 鉴定具有异常分数缩短的患者 |
| EP2730923A1 (en) | 2012-11-09 | 2014-05-14 | Roche Diagniostics GmbH | NTproBNP and cTnT based therapy guidance in heart failure |
| CA2893639C (en) | 2012-12-04 | 2021-01-05 | F. Hoffmann-La Roche Ag | Biomarkers in the selection of therapy of heart failure |
-
2012
- 2012-10-17 CN CN201280062128.XA patent/CN103998938B/zh active Active
- 2012-10-17 CA CA2846285A patent/CA2846285C/en active Active
- 2012-10-17 KR KR1020147010178A patent/KR101643147B1/ko active Active
- 2012-10-17 KR KR1020167019896A patent/KR101950561B1/ko active Active
- 2012-10-17 ES ES12775484.4T patent/ES2595028T3/es active Active
- 2012-10-17 CN CN201610329765.9A patent/CN105785053B/zh active Active
- 2012-10-17 ES ES16175468T patent/ES2824110T3/es active Active
- 2012-10-17 SG SG2014014559A patent/SG2014014559A/en unknown
- 2012-10-17 EP EP12775484.4A patent/EP2769227B1/en active Active
- 2012-10-17 BR BR112014007007-5A patent/BR112014007007B1/pt active IP Right Grant
- 2012-10-17 EP EP16175468.4A patent/EP3088900B1/en not_active Revoked
- 2012-10-17 MX MX2014003496A patent/MX347355B/es active IP Right Grant
- 2012-10-17 BR BR122021026652-2A patent/BR122021026652B1/pt active IP Right Grant
- 2012-10-17 JP JP2014536214A patent/JP6117805B2/ja active Active
- 2012-10-17 WO PCT/EP2012/070553 patent/WO2013057135A1/en not_active Ceased
- 2012-10-17 AU AU2012324967A patent/AU2012324967B2/en active Active
-
2014
- 2014-04-14 US US14/251,803 patent/US20140220604A1/en not_active Abandoned
-
2015
- 2015-09-21 US US14/859,616 patent/US20160011210A1/en not_active Abandoned
-
2016
- 2016-10-05 US US15/285,798 patent/US20170023588A1/en not_active Abandoned
- 2016-11-04 JP JP2016216261A patent/JP6412085B2/ja active Active
-
2018
- 2018-03-05 US US15/911,695 patent/US11047865B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX347355B (es) | Diagnostico basado en troponina y en peptido natriuretico cerebral (bnp) de pacientes en riesgo y de causa de ataque. | |
| EA201391187A1 (ru) | Способ диагностики злокачественной опухоли и набор для диагностики путем измерения активности nk-клеток | |
| EP4321866A3 (en) | Gdf-15 as a diagnostic marker to predict the clinical outcome of a treatment with immune checkpoint blockers | |
| MX2018008882A (es) | Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro. | |
| EP4060048A3 (en) | Non-invasive diagnostic method for diagnosing bladder cancer | |
| IN2014CN04326A (es) | ||
| PH12014501682A1 (en) | Composition and method for diagnosis and treatment of diseases associated with neurite degeneration | |
| WO2011092285A3 (en) | Means and methods for diagnosing heart failure in a subject | |
| WO2013033609A3 (en) | Methods and compositions for the treatment and diagnosis of cancer | |
| EA201590247A1 (ru) | Антитела к siglec-15 | |
| MX358541B (es) | Metodos para predecir el riesgo de desarrollar hipertension. | |
| IN2015DN00678A (es) | ||
| MX360479B (es) | Anticuerpos contra microbioma, factores de estres y marcadores de mastocitos como marcadores de diagnostico para ibs. | |
| EA201690213A1 (ru) | Композиции и способ лечения связанных с комплементом состояний | |
| WO2012094550A3 (en) | Assays and methods of treatment relating to vitamin d insufficiency | |
| MX2015008436A (es) | Composiciones para permeabilizar celulas sanguineos fijos y sus usos. | |
| EA201300817A1 (ru) | Способ улучшенного приживления гемопоэтических стволовых клеток | |
| NZ711543A (en) | Anti-cd83 antibodies and use thereof | |
| FI20115670A0 (fi) | Kardiovaskulaarinen in vitro-malli | |
| WO2014179737A3 (en) | Assays and methods of treatment relating to vitamin d insufficiency | |
| WO2011083461A3 (en) | Method for diagnosing and monitoring schizophrenia and tauopathies | |
| WO2014169011A3 (en) | Methods for treating immune diseases | |
| EP2571504A4 (en) | Use of aromatase inhibitors for synchronizing ovulation, inducing superovulation or double ovulation and improving twinning and fertility in a mammal | |
| WO2014047442A3 (en) | Biomarkers for assessing treatment of sialic acid deficiency diseases and conditions | |
| WO2011163639A3 (en) | Cell aging as a unique biomarker of major depression |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |