MX344112B - Metodo y dispositivo para el tratamiento de trastornos del colesterol en la sangre. - Google Patents
Metodo y dispositivo para el tratamiento de trastornos del colesterol en la sangre.Info
- Publication number
- MX344112B MX344112B MX2013002681A MX2013002681A MX344112B MX 344112 B MX344112 B MX 344112B MX 2013002681 A MX2013002681 A MX 2013002681A MX 2013002681 A MX2013002681 A MX 2013002681A MX 344112 B MX344112 B MX 344112B
- Authority
- MX
- Mexico
- Prior art keywords
- abnormal
- levels
- blood cholesterol
- treatment
- treating blood
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/12—Blood circulatory system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Obesity (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
La presente invención se refiere a células de sangre total sin plasma, estando el plasma separado delas células de sangre total mediante plasmaféresis extracorporal, para su utilización en el tratamiento de tratamiento de trastornos del colesterol, en donde dichas células de sangre total están adaptadas para ser administrables a un paciente que presenta niveles de colesterol total anormales, niveles de LDL anormales y/o niveles de HDL anormales cuando se miden antes del tratamiento, en un primer régimen de tratamiento que comprende dos o más ciclos, en donde el primer régimen de tratamiento disminuye los niveles de LDL en pacientes que presenta niveles de LDL anormales y/o incrementa los niveles de LDL en pacientes que presentan niveles de LDL anormales y en donde cada ciclo posterior al primer régimen de tratamiento mantiene el nuevo nivel de colesterol total más bajo, nivel de LDL más bajo, y/o nivel de HDL más alto.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/418,123 US10624924B2 (en) | 2012-03-12 | 2012-03-12 | Method and device for treating blood cholesterol disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013002681A MX2013002681A (es) | 2013-09-12 |
MX344112B true MX344112B (es) | 2016-11-30 |
Family
ID=47891413
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013002681A MX344112B (es) | 2012-03-12 | 2013-03-08 | Metodo y dispositivo para el tratamiento de trastornos del colesterol en la sangre. |
Country Status (24)
Country | Link |
---|---|
US (1) | US10624924B2 (es) |
EP (1) | EP2638918B1 (es) |
JP (1) | JP6218401B2 (es) |
KR (2) | KR20130105452A (es) |
CN (2) | CN103301520A (es) |
AR (1) | AR090295A1 (es) |
AU (1) | AU2013201550B2 (es) |
BR (1) | BR102013005877B1 (es) |
CA (1) | CA2809012C (es) |
CL (1) | CL2013000667A1 (es) |
ES (1) | ES2598241T3 (es) |
HK (1) | HK1185791A1 (es) |
HU (1) | HUE029681T2 (es) |
IL (1) | IL225129A (es) |
MX (1) | MX344112B (es) |
MY (1) | MY169320A (es) |
NZ (1) | NZ608133A (es) |
PL (1) | PL2638918T3 (es) |
PT (1) | PT2638918T (es) |
RU (1) | RU2625774C2 (es) |
SG (1) | SG193729A1 (es) |
TW (1) | TWI554275B (es) |
UY (1) | UY34667A (es) |
ZA (1) | ZA201301815B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10624924B2 (en) | 2012-03-12 | 2020-04-21 | Grifols, S.A. | Method and device for treating blood cholesterol disorders |
AU2015201496B2 (en) * | 2014-06-03 | 2019-10-31 | Grifols Worldwide Operations Limited | Use of plasmapheresis to treat blood pressure disorders |
Family Cites Families (44)
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US4374731A (en) | 1980-03-06 | 1983-02-22 | Baxter Travenol Laboratories, Inc. | Method and apparatus for obtaining a desired rate of plasma collection from a membrane plasmapheresis filter |
US4350156A (en) | 1980-05-29 | 1982-09-21 | Japan Foundation For Artificial Organs | Method and apparatus for on-line filtration removal of macromolecules from a physiological fluid |
US4540401A (en) * | 1983-02-22 | 1985-09-10 | Applied Immune Sciences, Inc. | In vivo therapeutic apheresis using lipid vesicles |
AU4409285A (en) | 1984-06-29 | 1986-01-24 | Hemascience Laboratories Inc. | Blood extraction and reinfusion flow control system and method |
US5258149A (en) | 1990-11-27 | 1993-11-02 | W. R. Grace & Co.-Conn. | Process of making a membrane for high efficiency removal of low density lipoprotein-cholesterol from whole blood |
CA2095424A1 (en) | 1992-05-14 | 1993-11-15 | Marc Ellous Parham | Microporous polysulfone support suitable for removal of low density lipoprotein-cholesterol |
JPH06254152A (ja) * | 1993-03-03 | 1994-09-13 | Terumo Corp | 血漿交換装置 |
JPH0788179A (ja) * | 1993-09-22 | 1995-04-04 | Terumo Corp | 血漿交換装置 |
RU2113240C1 (ru) | 1995-05-05 | 1998-06-20 | Акционерное общество закрытого типа "Оптика" | Способ мембранного плазмафереза по одноигольной схеме под действием силы тяжести и устройство для его осуществления |
EP0832193A1 (en) | 1995-05-26 | 1998-04-01 | Diacrin, Inc. | Porcine hepatocytes for use in treatment of disorders characterized by insufficient liver function |
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FR2747591B1 (fr) | 1996-04-19 | 1998-05-22 | Hospal Ind | Appareil medical pour le traitement extracorporel du sang ou du plasma et procedes de fabrication de cet appareil |
JP2000512635A (ja) * | 1996-06-07 | 2000-09-26 | イーライ リリー アンド カンパニー | Obタンパク質を結合するタンパク質 |
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RU2153168C2 (ru) * | 1997-11-25 | 2000-07-20 | Научно-исследовательский институт кардиологии | Способ определения показаний к проведению плазмафереза при лечении стенокардии |
DE19821534C1 (de) | 1998-05-14 | 1999-08-19 | Braun Melsungen Ag | Blutreinigungsmaschine |
JP2002533169A (ja) | 1998-12-29 | 2002-10-08 | オキュロジックス コーポレイション | レオロジー的処置方法および関連するアフェレーシスシステム |
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JP2012512908A (ja) | 2008-12-19 | 2012-06-07 | アンセラ・ファーマシューティカルズ・インコーポレイテッド | 分泌ホスホリパーゼa2(spla2)インヒビターまたはspla2インヒビター併用療法を用いる主要心臓有害イベントおよび急性冠症候群の治療 |
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US10624924B2 (en) | 2012-03-12 | 2020-04-21 | Grifols, S.A. | Method and device for treating blood cholesterol disorders |
-
2012
- 2012-03-12 US US13/418,123 patent/US10624924B2/en active Active
-
2013
- 2013-03-05 ES ES13157889.0T patent/ES2598241T3/es active Active
- 2013-03-05 EP EP13157889.0A patent/EP2638918B1/en active Active
- 2013-03-05 PT PT131578890T patent/PT2638918T/pt unknown
- 2013-03-05 HU HUE13157889A patent/HUE029681T2/en unknown
- 2013-03-05 PL PL13157889T patent/PL2638918T3/pl unknown
- 2013-03-07 ZA ZA2013/01815A patent/ZA201301815B/en unknown
- 2013-03-07 CA CA2809012A patent/CA2809012C/en active Active
- 2013-03-08 TW TW102108168A patent/TWI554275B/zh not_active IP Right Cessation
- 2013-03-08 MX MX2013002681A patent/MX344112B/es active IP Right Grant
- 2013-03-08 MY MYPI2013700376A patent/MY169320A/en unknown
- 2013-03-10 IL IL225129A patent/IL225129A/en active IP Right Grant
- 2013-03-11 RU RU2013110503A patent/RU2625774C2/ru active
- 2013-03-11 AU AU2013201550A patent/AU2013201550B2/en active Active
- 2013-03-11 UY UY0001034667A patent/UY34667A/es not_active Application Discontinuation
- 2013-03-11 AR ARP130100773A patent/AR090295A1/es not_active Application Discontinuation
- 2013-03-11 CL CL2013000667A patent/CL2013000667A1/es unknown
- 2013-03-12 JP JP2013048810A patent/JP6218401B2/ja active Active
- 2013-03-12 SG SG2013018247A patent/SG193729A1/en unknown
- 2013-03-12 BR BR102013005877-7A patent/BR102013005877B1/pt active IP Right Grant
- 2013-03-12 NZ NZ608133A patent/NZ608133A/en unknown
- 2013-03-12 CN CN2013100785746A patent/CN103301520A/zh active Pending
- 2013-03-12 CN CN201711120194.9A patent/CN107754038A/zh active Pending
- 2013-03-12 KR KR1020130026154A patent/KR20130105452A/ko active Application Filing
- 2013-11-25 HK HK13113090.7A patent/HK1185791A1/zh unknown
-
2018
- 2018-06-25 KR KR1020180072810A patent/KR101908899B1/ko active IP Right Grant
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