MX344112B - Metodo y dispositivo para el tratamiento de trastornos del colesterol en la sangre. - Google Patents

Metodo y dispositivo para el tratamiento de trastornos del colesterol en la sangre.

Info

Publication number
MX344112B
MX344112B MX2013002681A MX2013002681A MX344112B MX 344112 B MX344112 B MX 344112B MX 2013002681 A MX2013002681 A MX 2013002681A MX 2013002681 A MX2013002681 A MX 2013002681A MX 344112 B MX344112 B MX 344112B
Authority
MX
Mexico
Prior art keywords
abnormal
levels
blood cholesterol
treatment
treating blood
Prior art date
Application number
MX2013002681A
Other languages
English (en)
Other versions
MX2013002681A (es
Inventor
Grifols Lucas Victor
Grifols Roura Victor
Original Assignee
Grifols Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols Sa filed Critical Grifols Sa
Publication of MX2013002681A publication Critical patent/MX2013002681A/es
Publication of MX344112B publication Critical patent/MX344112B/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3496Plasmapheresis; Leucopheresis; Lymphopheresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/75General characteristics of the apparatus with filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/12Blood circulatory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La presente invención se refiere a células de sangre total sin plasma, estando el plasma separado delas células de sangre total mediante plasmaféresis extracorporal, para su utilización en el tratamiento de tratamiento de trastornos del colesterol, en donde dichas células de sangre total están adaptadas para ser administrables a un paciente que presenta niveles de colesterol total anormales, niveles de LDL anormales y/o niveles de HDL anormales cuando se miden antes del tratamiento, en un primer régimen de tratamiento que comprende dos o más ciclos, en donde el primer régimen de tratamiento disminuye los niveles de LDL en pacientes que presenta niveles de LDL anormales y/o incrementa los niveles de LDL en pacientes que presentan niveles de LDL anormales y en donde cada ciclo posterior al primer régimen de tratamiento mantiene el nuevo nivel de colesterol total más bajo, nivel de LDL más bajo, y/o nivel de HDL más alto.
MX2013002681A 2012-03-12 2013-03-08 Metodo y dispositivo para el tratamiento de trastornos del colesterol en la sangre. MX344112B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13/418,123 US10624924B2 (en) 2012-03-12 2012-03-12 Method and device for treating blood cholesterol disorders

Publications (2)

Publication Number Publication Date
MX2013002681A MX2013002681A (es) 2013-09-12
MX344112B true MX344112B (es) 2016-11-30

Family

ID=47891413

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013002681A MX344112B (es) 2012-03-12 2013-03-08 Metodo y dispositivo para el tratamiento de trastornos del colesterol en la sangre.

Country Status (24)

Country Link
US (1) US10624924B2 (es)
EP (1) EP2638918B1 (es)
JP (1) JP6218401B2 (es)
KR (2) KR20130105452A (es)
CN (2) CN103301520A (es)
AR (1) AR090295A1 (es)
AU (1) AU2013201550B2 (es)
BR (1) BR102013005877B1 (es)
CA (1) CA2809012C (es)
CL (1) CL2013000667A1 (es)
ES (1) ES2598241T3 (es)
HK (1) HK1185791A1 (es)
HU (1) HUE029681T2 (es)
IL (1) IL225129A (es)
MX (1) MX344112B (es)
MY (1) MY169320A (es)
NZ (1) NZ608133A (es)
PL (1) PL2638918T3 (es)
PT (1) PT2638918T (es)
RU (1) RU2625774C2 (es)
SG (1) SG193729A1 (es)
TW (1) TWI554275B (es)
UY (1) UY34667A (es)
ZA (1) ZA201301815B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10624924B2 (en) 2012-03-12 2020-04-21 Grifols, S.A. Method and device for treating blood cholesterol disorders
AU2015201496B2 (en) * 2014-06-03 2019-10-31 Grifols Worldwide Operations Limited Use of plasmapheresis to treat blood pressure disorders

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Also Published As

Publication number Publication date
IL225129A (en) 2017-02-28
BR102013005877B1 (pt) 2021-10-26
US10624924B2 (en) 2020-04-21
JP6218401B2 (ja) 2017-10-25
CN107754038A (zh) 2018-03-06
TWI554275B (zh) 2016-10-21
HUE029681T2 (en) 2017-02-28
AU2013201550B2 (en) 2015-07-02
IL225129A0 (en) 2013-06-27
RU2013110503A (ru) 2014-09-20
KR101908899B1 (ko) 2018-10-16
HK1185791A1 (zh) 2014-02-28
BR102013005877A2 (pt) 2017-07-11
TW201340973A (zh) 2013-10-16
UY34667A (es) 2013-10-31
NZ608133A (en) 2014-09-26
MY169320A (en) 2019-03-21
CA2809012A1 (en) 2013-09-12
AU2013201550A1 (en) 2013-09-26
US20130236559A1 (en) 2013-09-12
JP2013188475A (ja) 2013-09-26
CA2809012C (en) 2020-04-14
KR20180074646A (ko) 2018-07-03
ES2598241T3 (es) 2017-01-26
EP2638918A1 (en) 2013-09-18
PL2638918T3 (pl) 2017-01-31
MX2013002681A (es) 2013-09-12
KR20130105452A (ko) 2013-09-25
ZA201301815B (en) 2013-11-27
SG193729A1 (en) 2013-10-30
PT2638918T (pt) 2016-10-24
CL2013000667A1 (es) 2013-07-12
RU2625774C2 (ru) 2017-07-18
AR090295A1 (es) 2014-11-05
EP2638918B1 (en) 2016-08-31
CN103301520A (zh) 2013-09-18

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