MX343225B - Nuevos derivados de aril-benzocicloalquil-amida. - Google Patents

Nuevos derivados de aril-benzocicloalquil-amida.

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Publication number
MX343225B
MX343225B MX2013008312A MX2013008312A MX343225B MX 343225 B MX343225 B MX 343225B MX 2013008312 A MX2013008312 A MX 2013008312A MX 2013008312 A MX2013008312 A MX 2013008312A MX 343225 B MX343225 B MX 343225B
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MX
Mexico
Prior art keywords
benzocycloalkyl
amide derivatives
new aryl
aryl
new
Prior art date
Application number
MX2013008312A
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English (en)
Other versions
MX2013008312A (es
Inventor
Aebi Johannes
Binggeli Alfred
Kuehne Holger
Wang Haiyan
Hertel Cornelia
P Maerki Hans
Kuhn Bernd
Ashok Konkar Anish
Original Assignee
Hoffmann La Roche
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Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2013008312A publication Critical patent/MX2013008312A/es
Publication of MX343225B publication Critical patent/MX343225B/es

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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
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    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Abstract

La invención proporciona nuevos compuestos que tienen la fórmula general (I) (Ver Formula) en la que R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 y n tienen los significados aquí descritos, composiciones que contienen estos compuestos y métodos para la utilización de los compuestos.
MX2013008312A 2011-01-24 2012-01-18 Nuevos derivados de aril-benzocicloalquil-amida. MX343225B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11151890 2011-01-24
PCT/EP2012/050667 WO2012101011A2 (en) 2011-01-24 2012-01-18 New aryl-benzocycloalkyl amide derivatives

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BR112013018732A2 (pt) 2016-10-25
CN103328436B (zh) 2015-06-10
US8592426B2 (en) 2013-11-26
JP5986108B2 (ja) 2016-09-06
RU2013136777A (ru) 2015-03-10
EP2668155A2 (en) 2013-12-04

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