MX342039B - Composiciones y usos de materiales con actividad antimicrobiana elevada y toxicidad baja referencia cruzada a solicitudes previas. - Google Patents

Composiciones y usos de materiales con actividad antimicrobiana elevada y toxicidad baja referencia cruzada a solicitudes previas.

Info

Publication number
MX342039B
MX342039B MX2013002122A MX2013002122A MX342039B MX 342039 B MX342039 B MX 342039B MX 2013002122 A MX2013002122 A MX 2013002122A MX 2013002122 A MX2013002122 A MX 2013002122A MX 342039 B MX342039 B MX 342039B
Authority
MX
Mexico
Prior art keywords
compositions
materials
antimicrobial activity
low toxicity
high antimicrobial
Prior art date
Application number
MX2013002122A
Other languages
English (en)
Other versions
MX2013002122A (es
Inventor
P Bevilacqua Michael
Bentitez Diego
J Deming Timothy
A Hanson Jarrod
Koziol Lucas
Original Assignee
The Regents Of The Univ Of California *
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The Univ Of California * filed Critical The Regents Of The Univ Of California *
Publication of MX2013002122A publication Critical patent/MX2013002122A/es
Publication of MX342039B publication Critical patent/MX342039B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3526—Organic compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)

Abstract

La presente invención se refiere a los agentes antimicrobianos constituidos por copolipéptidos sintéticos mejorados contienen residuos aminoacídicos catiónicos y se pueden basar en una secuencia en bloque. Estos agentes antimicrobianos presentan una toxicidad baja para mamíferos y pueden dar lugar a un autoensamblaje dirigido. Los copolipéptidos sintéticos de la invención son útiles en el tratamiento de heridas y otras infecciones.
MX2013002122A 2010-08-23 2011-08-23 Composiciones y usos de materiales con actividad antimicrobiana elevada y toxicidad baja referencia cruzada a solicitudes previas. MX342039B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37619510P 2010-08-23 2010-08-23
PCT/US2011/048869 WO2012027411A2 (en) 2010-08-23 2011-08-23 Compositions and uses of materials with high antimicrobial activity and low toxicity

Publications (2)

Publication Number Publication Date
MX2013002122A MX2013002122A (es) 2013-06-05
MX342039B true MX342039B (es) 2016-09-09

Family

ID=45724032

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013002122A MX342039B (es) 2010-08-23 2011-08-23 Composiciones y usos de materiales con actividad antimicrobiana elevada y toxicidad baja referencia cruzada a solicitudes previas.

Country Status (16)

Country Link
US (3) US9017730B2 (es)
EP (1) EP2608800B1 (es)
JP (1) JP5902171B2 (es)
CN (1) CN103260635A (es)
AU (3) AU2011293468B2 (es)
BR (1) BR112013004436A2 (es)
CA (2) CA2809093C (es)
DK (1) DK2608800T3 (es)
ES (1) ES2622498T3 (es)
HU (1) HUE032899T2 (es)
LT (1) LT2608800T (es)
MX (1) MX342039B (es)
PL (1) PL2608800T3 (es)
PT (1) PT2608800T (es)
SG (1) SG188281A1 (es)
WO (1) WO2012027411A2 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2608800T (pt) 2010-08-23 2017-05-03 Amicrobe Inc Resumo
KR102141254B1 (ko) * 2012-03-23 2020-08-04 아미크로베, 인코포레이티드. 조직-적합성 특성을 갖는 항균물질의 조성물 및 용도
WO2016029920A1 (en) * 2014-08-29 2016-03-03 Aarhus Universitet Positively charged co-polymers for use as antimicrobial agents
US11298424B2 (en) 2014-10-01 2022-04-12 The Regents Of The University Of California Non-ionic and thermoresponsive diblock copolypeptide hydrogels for delivery of molecules and cells
CN106674329B (zh) * 2015-11-05 2021-07-23 程家维 具备抗微生物、抗癌/促进伤口愈合活性的肽及其用途
CN105708592B (zh) * 2016-04-17 2018-04-24 河南科技大学第一附属医院 一种手外科术后的手臂支架
AU2018249552A1 (en) * 2017-04-06 2019-10-31 Amicrobe, Inc. Compositions and uses of locally-applied antimicrobial synthetic cationic polypeptide(s) with enhanced performance and safety
CN111234034B (zh) * 2020-01-22 2021-10-08 国家纳米科学中心 一种调控细胞膜受体的多肽组合物及其制备方法和应用
JP2023521796A (ja) * 2020-04-08 2023-05-25 アミクローブ，インコーポレイテッド ウイルス感染症の予防及び治療のために局所投与される合成アミノ酸ポリマーの組成物及びその使用
US12090206B2 (en) 2020-04-23 2024-09-17 The Regents Of The University Of California Compositions comprising tri- and penta-block synthetic copolypeptide hydrogels
CA3188232A1 (en) * 2020-08-10 2022-02-17 Kushee-Nidhi Kush KUMAR Antifungal matrix formed from peptide hydrogels
CN112933108B (zh) * 2021-02-05 2024-07-23 华东理工大学 掺杂多肽聚合物的骨髓腔填充物及在骨髓炎治疗中的用途
CN114748681B (zh) * 2022-04-13 2023-03-10 四川大学 一种可注射自愈合水凝胶敷料及其制备方法、用途

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US6686446B2 (en) 1998-03-19 2004-02-03 The Regents Of The University Of California Methods and compositions for controlled polypeptide synthesis
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Also Published As

Publication number Publication date
PT2608800T (pt) 2017-05-03
WO2012027411A2 (en) 2012-03-01
PL2608800T3 (pl) 2017-08-31
HUE032899T2 (hu) 2017-11-28
US20150366193A1 (en) 2015-12-24
EP2608800A4 (en) 2014-01-22
SG188281A1 (en) 2013-04-30
AU2016203767A1 (en) 2016-06-23
AU2014213503A1 (en) 2014-09-04
CA2912577A1 (en) 2012-03-01
DK2608800T3 (da) 2017-05-01
AU2014213503B2 (en) 2016-03-10
MX2013002122A (es) 2013-06-05
US20130267458A1 (en) 2013-10-10
JP2013536242A (ja) 2013-09-19
JP5902171B2 (ja) 2016-04-13
LT2608800T (lt) 2017-05-10
CA2912577C (en) 2019-02-19
CA2809093A1 (en) 2012-03-01
WO2012027411A9 (en) 2012-05-31
AU2011293468A1 (en) 2013-03-14
AU2016203767B2 (en) 2018-04-26
AU2011293468B2 (en) 2014-05-15
EP2608800B1 (en) 2017-01-18
US20200288709A1 (en) 2020-09-17
CA2809093C (en) 2015-11-24
ES2622498T3 (es) 2017-07-06
US10448634B2 (en) 2019-10-22
EP2608800A2 (en) 2013-07-03
WO2012027411A3 (en) 2012-07-19
US9017730B2 (en) 2015-04-28
CN103260635A (zh) 2013-08-21
BR112013004436A2 (pt) 2016-06-21

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