MX338591B - Dispositivos intravaginales con un soporte rigido, metodos de fabricacion y usos de los mismos. - Google Patents

Dispositivos intravaginales con un soporte rigido, metodos de fabricacion y usos de los mismos.

Info

Publication number
MX338591B
MX338591B MX2011001605A MX2011001605A MX338591B MX 338591 B MX338591 B MX 338591B MX 2011001605 A MX2011001605 A MX 2011001605A MX 2011001605 A MX2011001605 A MX 2011001605A MX 338591 B MX338591 B MX 338591B
Authority
MX
Mexico
Prior art keywords
rigid support
making
methods
intravaginal devices
matrix
Prior art date
Application number
MX2011001605A
Other languages
English (en)
Other versions
MX2011001605A (es
Inventor
Salah U Ahmed
Jiaxiang Tsao
Original Assignee
Teva Womens Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Womens Health Inc filed Critical Teva Womens Health Inc
Publication of MX2011001605A publication Critical patent/MX2011001605A/es
Publication of MX338591B publication Critical patent/MX338591B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
  • Steroid Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)

Abstract

La presente invención se refiere a dispositivos intravaginales que tienen un soporte rígido, métodos de fabricación y usos de los mismos. Los dispositivos comprenden (a) un soporte rígido que tiene una Dureza Shore A de por lo menos aproximadamente 20 y una resistencia a la tracción de por lo menos aproximadamente 1 MPa, (b) una matriz y (c) un agente activo dispersado en la matriz, en donde el soporte y la matriz están adyacentes y en donde el dispositivo es anular.
MX2011001605A 2008-08-12 2009-08-12 Dispositivos intravaginales con un soporte rigido, metodos de fabricacion y usos de los mismos. MX338591B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8831408P 2008-08-12 2008-08-12
PCT/US2009/004607 WO2010019226A1 (en) 2008-08-12 2009-08-12 Intravaginal devices with a rigid support, methods of making, and uses thereof

Publications (2)

Publication Number Publication Date
MX2011001605A MX2011001605A (es) 2011-05-19
MX338591B true MX338591B (es) 2016-04-25

Family

ID=41669143

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011001605A MX338591B (es) 2008-08-12 2009-08-12 Dispositivos intravaginales con un soporte rigido, metodos de fabricacion y usos de los mismos.

Country Status (9)

Country Link
US (1) US20100040671A1 (es)
EP (1) EP2320871A4 (es)
JP (1) JP2011530379A (es)
AR (1) AR074528A1 (es)
AU (1) AU2009282496B2 (es)
CA (1) CA2733727A1 (es)
EA (1) EA021371B1 (es)
MX (1) MX338591B (es)
WO (1) WO2010019226A1 (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013000002A (es) * 2001-07-27 2013-04-29 Teva Womens Health Inc Metodos de tratamiento de condiciones patologicas asociadas con vejiga hiperactiva.
AU2010256558B2 (en) 2009-06-03 2013-10-03 Forsight Labs, Llc Anterior segment drug delivery
PL2547332T3 (pl) * 2010-03-16 2019-07-31 Titan Pharmaceuticals, Inc. Heterogeniczne wyroby wszczepialne do podaży leku
AU2011238710B2 (en) * 2010-03-28 2015-08-20 Evestra, Inc. Intravaginal drug delivery device
US9220692B2 (en) * 2010-05-05 2015-12-29 Teva Women's Health, Inc. Methods of reducing symptoms in subjects using single dosage forms with tapering release rates
KR20130045332A (ko) * 2010-06-22 2013-05-03 지아시앙 차오 항콜린제를 포함하는 질내 기구 및 그 제조방법
MX2013002016A (es) * 2010-08-20 2013-03-25 Teva Womens Health Inc Dispositivos intravaginales, metodos de fabricacion y usos de los mismos.
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
ZA201107786B (en) * 2010-10-26 2012-07-25 Maurice Roger Pope An inhibotor of pathogens
KR101993786B1 (ko) * 2010-11-12 2019-06-28 더 유니버시티 오브 유타 리서치 파운데이션 윤활제의 제어된 전달을 위한 질내 장치
US20120259163A1 (en) * 2011-04-11 2012-10-11 Nancy Karapasha Method for treating urinary incontinence
US20120259160A1 (en) * 2011-04-11 2012-10-11 Nancy Karapasha Pessary device having improved comfort
HUE032237T2 (en) * 2011-08-17 2017-09-28 Ironwood Pharmaceuticals Inc Treatments for gastrointestinal disorders
RU2740680C2 (ru) 2011-09-14 2021-01-19 Форсайт Вижн5, Инк. Глазное вкладочное устройство и способы
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
RS62297B1 (sr) 2011-11-23 2021-09-30 Therapeuticsmd Inc Prirodne kombinovane hormonske supstitucione formulacije i terapije
TW201332585A (zh) 2012-02-14 2013-08-16 Chemo Res S L 核鞘藥物遞送裝置
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
EP2911623B1 (en) 2012-10-26 2019-08-14 Forsight Vision5, Inc. Ophthalmic system for sustained release of drug to eye
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2015041353A1 (ja) * 2013-09-20 2015-03-26 潤子 八木 子宮脱又は子宮下垂治療用リングペッサリー
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
EP3017809A1 (en) 2014-11-07 2016-05-11 Ferring B.V. Drug-device unit containing quinagolide
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
CA3018148C (en) 2016-03-23 2024-02-20 The University Of North Carolina At Chapel Hill Geometrically complex intravaginal rings, systems and methods of making the same
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
AR125269A1 (es) * 2021-04-01 2023-06-28 Ceva Sante Animale Composiciones de progesterona de liberación controlada y sus utilizaciones
WO2023031218A1 (en) 2021-08-31 2023-03-09 Ferring B.V. Diagnosis and treatment of ectopic endometriosis

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3545439A (en) * 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
BE791632A (fr) * 1971-11-20 1973-05-21 Schering Ag Supports a base de caoutchouc siliconique pour agents medicamenteux
US3920805A (en) * 1971-12-09 1975-11-18 Upjohn Co Pharmaceutical devices and method
US4034749A (en) * 1973-12-06 1977-07-12 Schering Aktiengesellschaft Intrauterine contraceptive device
US3993072A (en) * 1974-08-28 1976-11-23 Alza Corporation Microporous drug delivery device
DE2445971A1 (de) * 1974-09-24 1976-04-08 Schering Ag Arzneimittelwirkstofftraeger ii
US4155991A (en) * 1974-10-18 1979-05-22 Schering Aktiengesellschaft Vaginal ring
IL48277A (en) * 1974-10-18 1978-03-10 Schering Ag Vaginal ring
US4215691A (en) * 1978-10-11 1980-08-05 Alza Corporation Vaginal contraceptive system made from block copolymer
US4286587A (en) * 1978-10-11 1981-09-01 Alza Corporation Vaginal drug delivery system made from polymer
US4292965A (en) * 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
US4308867A (en) * 1979-03-23 1982-01-05 Roseman Theodore J Two-member medicated device for rate-controlled administration of lipophilic pharmaceuticals
US4249531A (en) * 1979-07-05 1981-02-10 Alza Corporation Bioerodible system for delivering drug manufactured from poly(carboxylic acid)
US4402695A (en) * 1980-01-21 1983-09-06 Alza Corporation Device for delivering agent in vagina
DE3040978A1 (de) * 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
NZ200564A (en) * 1982-05-10 1987-03-06 Ahi Operations Ltd Device for slowly releasing chemicals into body cavities of animals
US4629449A (en) * 1982-07-29 1986-12-16 Alza Corporation Vaginal dispenser for dispensing beneficial hormone
US4961931A (en) * 1982-07-29 1990-10-09 Alza Corporation Method for the management of hyperplasia
US4553972A (en) * 1983-05-20 1985-11-19 Syntex (U.S.A.) Inc. Disposable intravaginal contraceptive devices releasing 1-substituted imidazoles
NL8302103A (nl) * 1983-06-13 1985-01-02 Fundatech Sa Intravaginaal contraceptisch middel.
US4589880A (en) * 1983-07-14 1986-05-20 Southern Research Institute Disposable spermicide-releasing diaphragm
US4601893A (en) * 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
AU601170B2 (en) * 1985-06-19 1990-09-06 Fortune Capital Management B.V. Pessary
US4827946A (en) * 1988-01-06 1989-05-09 Steven Kaali Electrified vaginal ring
WO1994016652A1 (en) * 1993-01-26 1994-08-04 Page Hanes, Inc. Disposable vaginal device
US6544546B1 (en) * 1995-07-04 2003-04-08 Akzo Nobel, N.V. Ring-shaped devices
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
IL123813A0 (en) * 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
US6165166A (en) * 1997-04-25 2000-12-26 Schneider (Usa) Inc. Trilayer, extruded medical tubing and medical devices incorporating such tubing
US6982091B2 (en) * 2001-08-29 2006-01-03 Umd, Inc. Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy
US7744916B2 (en) * 1997-06-11 2010-06-29 Umd, Inc. Coated vaginal device for delivery of anti-migraine and anti-nausea drugs
US6572874B1 (en) * 1998-05-15 2003-06-03 Umd, Inc. Vaginal delivery of bisphosphonates
US20050276836A1 (en) * 1997-06-11 2005-12-15 Michelle Wilson Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
JP2002513690A (ja) * 1998-05-01 2002-05-14 エフイ−アイ エンタープライジズ,リミティド 制御放出デバイスの射出成形製造方法
US6663639B1 (en) * 1999-06-22 2003-12-16 Ndo Surgical, Inc. Methods and devices for tissue reconfiguration
US7314716B2 (en) * 1999-11-19 2008-01-01 Mount Sinai School Of Medicine Gustducin γ subunit materials and methods
US6802807B2 (en) * 2001-01-23 2004-10-12 American Medical Systems, Inc. Surgical instrument and method
JP4273208B2 (ja) * 2001-03-30 2009-06-03 チッソ株式会社 婦人科疾患治療剤
US7005138B2 (en) * 2001-12-21 2006-02-28 Duramed Pharmaceuticals, Inc. Method of systematically delivering SSRIs
US7004171B2 (en) * 2002-02-25 2006-02-28 Hi-Gienic Intra Vaginal Technologies Ltd. System for transvaginal drug delivery
US7833545B2 (en) * 2003-04-29 2010-11-16 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
US20060275364A1 (en) * 2005-05-26 2006-12-07 Ahmed Salah U Flexible Solid Dosage Forms and Methods of Making and Using the Same

Also Published As

Publication number Publication date
EP2320871A4 (en) 2012-09-19
AU2009282496B2 (en) 2015-08-06
CA2733727A1 (en) 2010-02-18
JP2011530379A (ja) 2011-12-22
EP2320871A1 (en) 2011-05-18
WO2010019226A1 (en) 2010-02-18
EA021371B1 (ru) 2015-06-30
AR074528A1 (es) 2011-01-26
US20100040671A1 (en) 2010-02-18
MX2011001605A (es) 2011-05-19
EA201170199A1 (ru) 2011-08-30
AU2009282496A1 (en) 2010-02-18

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