MX338297B - Metodos y composiciones relacionados con fusiones de alk para el diagnostico y tratamiento de cancer. - Google Patents
Metodos y composiciones relacionados con fusiones de alk para el diagnostico y tratamiento de cancer.Info
- Publication number
- MX338297B MX338297B MX2011012162A MX2011012162A MX338297B MX 338297 B MX338297 B MX 338297B MX 2011012162 A MX2011012162 A MX 2011012162A MX 2011012162 A MX2011012162 A MX 2011012162A MX 338297 B MX338297 B MX 338297B
- Authority
- MX
- Mexico
- Prior art keywords
- fusions
- methods
- alk
- diagnosing
- treating cancer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17893709P | 2009-05-15 | 2009-05-15 | |
| PCT/US2010/035147 WO2010132888A2 (en) | 2009-05-15 | 2010-05-17 | Methods and compositions relating to fusions of alk for diagnosing and treating cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2011012162A MX2011012162A (es) | 2012-01-30 |
| MX338297B true MX338297B (es) | 2016-04-11 |
Family
ID=43085621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011012162A MX338297B (es) | 2009-05-15 | 2010-05-17 | Metodos y composiciones relacionados con fusiones de alk para el diagnostico y tratamiento de cancer. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20120208713A1 (enExample) |
| EP (2) | EP3133167B1 (enExample) |
| JP (2) | JP2012526563A (enExample) |
| CN (1) | CN102575287B (enExample) |
| AU (1) | AU2010248782B2 (enExample) |
| BR (1) | BRPI1012140A2 (enExample) |
| CA (1) | CA2762108A1 (enExample) |
| ES (1) | ES2700098T3 (enExample) |
| MX (1) | MX338297B (enExample) |
| RU (1) | RU2562144C2 (enExample) |
| WO (1) | WO2010132888A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8168383B2 (en) | 2006-04-14 | 2012-05-01 | Cell Signaling Technology, Inc. | Gene defects and mutant ALK kinase in human solid tumors |
| ES2561406T3 (es) | 2006-04-14 | 2016-02-26 | Cell Signaling Technology, Inc. | Defectos de genes y quinasa ALK mutante en tumores sólidos humanos |
| TWI518325B (zh) | 2010-02-04 | 2016-01-21 | 自治醫科大學 | 對ａｌｋ抑制劑具有先抗性或後抗性癌症的識別、判斷和治療 |
| WO2012019132A2 (en) | 2010-08-06 | 2012-02-09 | Cell Signaling Technology, Inc. | Anaplastic lymphoma kinase in kidney cancer |
| JP2015508644A (ja) * | 2012-02-08 | 2015-03-23 | インサイト ジェネティクス インコーポレイテッド | 癌の診断および治療のためのｒｏｓ１の融合体に関する方法および組成物 |
| CN102888452B (zh) * | 2012-05-18 | 2014-08-27 | 复旦大学附属肿瘤医院 | 一种筛查alk融合基因的方法 |
| US9084456B1 (en) * | 2012-05-28 | 2015-07-21 | Jack Zemer | Linkage for jewelry components |
| WO2014026133A1 (en) * | 2012-08-09 | 2014-02-13 | Insight Genetics, Inc. | Methods and compositions relating to alk for diagnosing and treating inflammatory breast and other human cancers |
| CA2882759C (en) * | 2012-08-31 | 2018-11-20 | The Regents Of The University Of Colorado | Detection of the ntrk1-mprip gene fusion for cancer diagnosis |
| CN103805687B (zh) * | 2012-11-09 | 2016-06-01 | 益善生物技术股份有限公司 | Alk融合基因检测的pcr引物、试剂盒和液相芯片 |
| RU2509153C1 (ru) * | 2012-11-28 | 2014-03-10 | Федеральное государственное бюджетное учреждение "Российский онкологический научный центр имени Н.Н. Блохина" Российской академии медицинских наук (ФГБУ "РОНЦ им. Н.Н. Блохина" РАМН) | Способ анализа транслокаций eml4-alk, ассоциированных с чувствительностью рака легкого к противоопухолевой таргетной терапии |
| US10072298B2 (en) | 2013-04-17 | 2018-09-11 | Life Technologies Corporation | Gene fusions and gene variants associated with cancer |
| EP2986736B1 (en) * | 2013-04-17 | 2019-09-18 | Life Technologies Corporation | Gene fusions and gene variants associated with cancer |
| CN103290120B (zh) * | 2013-05-24 | 2015-03-25 | 厦门艾德生物医药科技有限公司 | 一种用于检测alk基因表达的探针、引物及试剂盒 |
| CN106414768B (zh) * | 2014-03-27 | 2020-05-29 | 生命技术公司 | 与癌症相关的基因融合体和基因变异体 |
| US9428812B2 (en) * | 2014-04-28 | 2016-08-30 | Insight Genetics, Inc. | Kit comprising primers for amplifying ALK kinase domain nucleic acids |
| WO2016106701A1 (zh) * | 2014-12-31 | 2016-07-07 | 深圳华大基因股份有限公司 | 检测非小细胞肺癌的qRT-PCR引物、探针、芯片、试剂盒、应用和方法 |
| CN107532209A (zh) * | 2015-04-17 | 2018-01-02 | 豪夫迈·罗氏有限公司 | 检测基因融合的多重pcr |
| CN107022610B (zh) * | 2017-04-01 | 2019-02-05 | 常州桐树生物科技有限公司 | 肿瘤驱动基因的检测芯片及其应用 |
| KR101987065B1 (ko) * | 2017-08-07 | 2019-06-10 | 주식회사 싸이토젠 | Eml4-alk유전자 변이 분석방법 |
| RU2681165C1 (ru) * | 2017-12-01 | 2019-03-04 | Общество с ограниченной ответственностью "Научно-Исследовательский Центр Молекулярной Биомедицины" (ООО "НИЦ МолБиоМед") | Способ определения активности теломеразы методом двойной амплификации теломерных повторов в реальном времени |
| CN111235272B (zh) * | 2020-01-10 | 2023-07-07 | 厦门艾德生物医药科技股份有限公司 | 一次性检测肺癌多重基因突变的组合物及其应用 |
| CN113005200B (zh) * | 2021-04-14 | 2023-07-04 | 深圳乐土生物科技有限公司 | 一种检测肉瘤融合基因突变的引物组合物、试剂盒及应用 |
| CN114807124B (zh) * | 2022-04-01 | 2023-09-12 | 上海信诺佰世医学检验有限公司 | 一种检测alk融合基因的引物和探针组合物、试剂盒及方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| AU8126694A (en) * | 1993-10-26 | 1995-05-22 | Affymax Technologies N.V. | Arrays of nucleic acid probes on biological chips |
| US6696548B2 (en) * | 1993-12-03 | 2004-02-24 | St. Jude Children's Research Hospital | Antibodies for recognition of alk protein tyrosine/kinase receptor |
| US5529925A (en) * | 1993-12-03 | 1996-06-25 | St. Jude Children's Research Hospital | Nucleic acid sequences and fusion proteins present in human t(2;5) lymphoma |
| US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| GB9812768D0 (en) * | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
| US7339033B2 (en) * | 1998-06-26 | 2008-03-04 | Genentech, Inc. | Pro1481 |
| GB0319227D0 (en) * | 2003-08-15 | 2003-09-17 | Novartis Ag | Organic compounds |
| ATE429495T1 (de) * | 2005-01-25 | 2009-05-15 | Sky Genetics Inc | Nukleinsäuren für die apoptose von krebszellen |
| WO2006085326A2 (en) * | 2005-02-10 | 2006-08-17 | Siano Mobile Silicon Ltd. | System and method for mitigating memory requirements |
| WO2006094073A2 (en) * | 2005-03-02 | 2006-09-08 | Acadia Pharmaceuticals Inc. | Functional bioluminescence energy resonance transfer (bret) assay to screen, identify and characterize receptor tyrosine kinase ligands |
| US20060286558A1 (en) * | 2005-06-15 | 2006-12-21 | Natalia Novoradovskaya | Normalization of samples for amplification reactions |
| CA2598893C (en) * | 2006-10-11 | 2012-04-10 | Astellas Pharma Inc. | Eml4-alk fusion gene |
| JP5562640B2 (ja) * | 2007-04-13 | 2014-07-30 | セル・シグナリング・テクノロジー・インコーポレイテツド | ヒト固形腫瘍における遺伝子欠失及び突然変異ａｌｋキナーゼ |
-
2010
- 2010-05-17 EP EP16175320.7A patent/EP3133167B1/en not_active Not-in-force
- 2010-05-17 CA CA2762108A patent/CA2762108A1/en not_active Abandoned
- 2010-05-17 AU AU2010248782A patent/AU2010248782B2/en not_active Ceased
- 2010-05-17 BR BRPI1012140A patent/BRPI1012140A2/pt not_active IP Right Cessation
- 2010-05-17 EP EP10775673A patent/EP2432900A4/en not_active Ceased
- 2010-05-17 CN CN201080031440.3A patent/CN102575287B/zh not_active Expired - Fee Related
- 2010-05-17 ES ES16175320T patent/ES2700098T3/es active Active
- 2010-05-17 RU RU2011151049/10A patent/RU2562144C2/ru not_active IP Right Cessation
- 2010-05-17 JP JP2012511069A patent/JP2012526563A/ja active Pending
- 2010-05-17 MX MX2011012162A patent/MX338297B/es active IP Right Grant
- 2010-05-17 WO PCT/US2010/035147 patent/WO2010132888A2/en not_active Ceased
- 2010-05-17 US US13/320,303 patent/US20120208713A1/en not_active Abandoned
-
2016
- 2016-01-04 JP JP2016000290A patent/JP6397833B2/ja not_active Expired - Fee Related
- 2016-10-26 US US15/334,974 patent/US20170183743A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012526563A (ja) | 2012-11-01 |
| RU2011151049A (ru) | 2013-06-20 |
| WO2010132888A3 (en) | 2011-01-20 |
| EP3133167B1 (en) | 2018-09-12 |
| RU2562144C2 (ru) | 2015-09-10 |
| AU2010248782A1 (en) | 2012-01-19 |
| CN102575287B (zh) | 2016-11-16 |
| CA2762108A1 (en) | 2010-11-18 |
| AU2010248782B2 (en) | 2015-06-11 |
| MX2011012162A (es) | 2012-01-30 |
| CN102575287A (zh) | 2012-07-11 |
| US20120208713A1 (en) | 2012-08-16 |
| EP3133167A1 (en) | 2017-02-22 |
| JP2016052332A (ja) | 2016-04-14 |
| US20170183743A1 (en) | 2017-06-29 |
| BRPI1012140A2 (pt) | 2016-05-03 |
| EP2432900A2 (en) | 2012-03-28 |
| ES2700098T3 (es) | 2019-02-14 |
| JP6397833B2 (ja) | 2018-09-26 |
| WO2010132888A2 (en) | 2010-11-18 |
| EP2432900A4 (en) | 2012-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |