MX337990B - Metodos para la prevencion y tratamiento de isquemia cerebral. - Google Patents
Metodos para la prevencion y tratamiento de isquemia cerebral.Info
- Publication number
- MX337990B MX337990B MX2012002374A MX2012002374A MX337990B MX 337990 B MX337990 B MX 337990B MX 2012002374 A MX2012002374 A MX 2012002374A MX 2012002374 A MX2012002374 A MX 2012002374A MX 337990 B MX337990 B MX 337990B
- Authority
- MX
- Mexico
- Prior art keywords
- prevention
- treatment
- cerebral ischemia
- methods
- amelioration
- Prior art date
Links
- 201000006474 Brain Ischemia Diseases 0.000 title abstract 2
- 206010008120 Cerebral ischaemia Diseases 0.000 title abstract 2
- 206010008118 cerebral infarction Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003961 neuronal insult Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27526909P | 2009-08-26 | 2009-08-26 | |
| PCT/US2010/046503 WO2011025785A1 (en) | 2009-08-26 | 2010-08-24 | Methods for the prevention and treatment of cerebral ischemia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2012002374A MX2012002374A (es) | 2012-04-10 |
| MX337990B true MX337990B (es) | 2016-03-30 |
Family
ID=42983642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012002374A MX337990B (es) | 2009-08-26 | 2010-08-24 | Metodos para la prevencion y tratamiento de isquemia cerebral. |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US20110207828A1 (enExample) |
| EP (1) | EP2470168B1 (enExample) |
| JP (2) | JP5785546B2 (enExample) |
| CN (1) | CN102647981B (enExample) |
| AU (1) | AU2010286704B2 (enExample) |
| BR (1) | BR112012004167A2 (enExample) |
| CA (1) | CA2772294C (enExample) |
| DK (1) | DK2470168T3 (enExample) |
| EA (1) | EA028677B1 (enExample) |
| ES (1) | ES2663709T3 (enExample) |
| HU (1) | HUE037592T2 (enExample) |
| MX (1) | MX337990B (enExample) |
| NO (1) | NO2470168T3 (enExample) |
| PL (1) | PL2470168T3 (enExample) |
| PT (1) | PT2470168T (enExample) |
| SI (1) | SI2470168T1 (enExample) |
| WO (1) | WO2011025785A1 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005032544A1 (en) | 2003-09-19 | 2005-04-14 | Galileo Pharmaceuticals, Inc. | Treatment of mitochondrial diseases |
| ES2714900T3 (es) | 2005-06-01 | 2019-05-30 | Bioelectron Tech Corp | Productos terapéuticos redox activos para el tratamiento de enfermedades mitocondriales y otras afecciones y modulación de biomarcadores energéticos |
| WO2007100652A2 (en) | 2006-02-22 | 2007-09-07 | Edison Pharmaceuticals, Inc. | Side chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| SI3456707T1 (sl) | 2007-11-06 | 2020-10-30 | Ptc Therapeutics, Inc. | Derivati 4-(P-kuinonil)-2-hidroksibutanamida za zdravljenje mitohondrijske bolezni |
| WO2009089224A1 (en) * | 2008-01-08 | 2009-07-16 | Edison Pharmaceuticals, Inc. | (HET) ARYL-p-QUINONE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES |
| JP5710277B2 (ja) | 2008-03-05 | 2015-04-30 | エジソン ファーマシューティカルズ, インコーポレイテッド | 酸化ストレス疾患の処置のための2−置換−p−キノン誘導体 |
| JP5798481B2 (ja) | 2008-06-25 | 2015-10-21 | エジソン ファーマシューティカルズ, インコーポレイテッド | 酸化ストレス疾患を治療するための2−ヘテロシクリルアミノアルキル−(p−キノン)誘導体 |
| JP2012502064A (ja) | 2008-09-10 | 2012-01-26 | エジソン ファーマシューティカルズ, インコーポレイテッド | 酸化還元活性治療剤を用いての広汎性発達障害の処置 |
| WO2010045220A1 (en) | 2008-10-14 | 2010-04-22 | Edison Pharmaceuticals, Inc. | Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the function of red cells |
| MY157119A (en) | 2008-10-28 | 2016-05-13 | Edison Pharmaceuticals Inc | Process for the production of alpha-tocotrienol and derivatives |
| HUE037574T2 (hu) | 2009-04-28 | 2018-09-28 | Bioelectron Tech Corp | Leber-féle örökletes optikus neuropátia és domináns optikus atrofia kezelése tokotrienol kinonokkal |
| CA2797644A1 (en) * | 2009-12-31 | 2011-07-07 | Edison Pharmaceuticals, Inc. | Treatment of leigh syndrome and leigh-like syndrome with tocotrienol quinones |
| CA2797581A1 (en) * | 2010-04-27 | 2011-11-03 | Edison Pharmaceuticals, Inc. | Formulations of quinones for the treatment of ophthalmic diseases |
| SI2680873T1 (sl) | 2011-03-03 | 2017-12-29 | Cidara Therapeutics, Inc. | Protiglivna sredstva in njihova uporaba |
| WO2012174286A1 (en) | 2011-06-14 | 2012-12-20 | Edison Pharmaceuticals, Inc. | Catechol derivatives for treatment of oxidative stress diseases |
| JP2014520894A (ja) | 2011-07-19 | 2014-08-25 | エジソン ファーマシューティカルズ, インコーポレイテッド | 非アルファトコトリエノールの存在下でのアルファトコトリエノールの選択的酸化のための方法 |
| GB201117808D0 (en) * | 2011-10-14 | 2011-11-30 | Siemens Medical Solutions | SUV correction following dose infiltration |
| PL3677252T3 (pl) * | 2012-03-19 | 2024-01-08 | Cidara Therapeutics, Inc. | Schematy dawkowania dla związków z klasy echinokandyn |
| CA2883882A1 (en) * | 2012-09-07 | 2014-03-13 | Edison Pharmaceuticals, Inc. | Benzoquinone derivatives for treating oxidative stress disorders |
| CN112451518B (zh) * | 2012-11-13 | 2025-02-21 | 因维克特斯生物技术有限公司 | 生育三烯酚的经粘膜递送 |
| US9868711B2 (en) | 2013-03-15 | 2018-01-16 | Bioelectron Technology Corporation | Phenazine-3-one and phenothiazine-3-one derivatives for treatment of oxidative stress disorders |
| CA2906145A1 (en) | 2013-03-15 | 2014-09-18 | Edison Pharmaceuticals, Inc. | Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders |
| US9296712B2 (en) | 2013-03-15 | 2016-03-29 | Edison Pharmaceuticals, Inc. | Resorufin derivatives for treatment of oxidative stress disorders |
| US9670170B2 (en) | 2013-03-15 | 2017-06-06 | Bioelectron Technology Corporation | Resorufin derivatives for treatment of oxidative stress disorders |
| RU2578451C1 (ru) * | 2014-12-09 | 2016-03-27 | Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Амурская Государственная Медицинская Академия" Министерства Здравоохранения Российской Федерации | Способ повышения устойчивости головного мозга к ишемии во время реконструктивных операций на брахиоцефальных артериях |
| WO2016100579A1 (en) | 2014-12-16 | 2016-06-23 | Edison Pharmaceuticals, Inc., | Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide |
| JP7117241B2 (ja) | 2015-12-16 | 2022-08-12 | ピーティーシー セラピューティクス, インコーポレイテッド | 混合されたトコール組成物からアルファ-トコトリエノールを富化するための改良された方法 |
| EP3389646A1 (en) | 2015-12-17 | 2018-10-24 | BioElectron Technology Corporation | Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| ES2955711T3 (es) | 2016-03-16 | 2023-12-05 | Cidara Therapeutics Inc | Regímenes de dosificación para el tratamiento de infecciones fúngicas |
| US10707531B1 (en) | 2016-09-27 | 2020-07-07 | New Dominion Enterprises Inc. | All-inorganic solvents for electrolytes |
| JP2018083799A (ja) | 2016-11-15 | 2018-05-31 | バイオエレクトロン テクノロジー コーポレイション | 2−置換アミノ−ナフト[1,2−d]イミダゾール−5−オン化合物またはその製薬学上許容される塩 |
| CN111050798A (zh) | 2017-07-12 | 2020-04-21 | 奇达拉治疗公司 | 用于治疗真菌感染的组合物和方法 |
| MX2021000157A (es) * | 2018-07-03 | 2021-12-10 | Venturis Therapeutics Inc | Composiciones y métodos para tratar el derrame cerebral. |
| KR102337954B1 (ko) * | 2018-08-16 | 2021-12-10 | 차의과학대학교 산학협력단 | 뇌졸중 치료용 조성물 및 이를 스크리닝하는 방법 |
| FI3866772T3 (fi) | 2018-10-17 | 2024-01-11 | Ptc Therapeutics Inc | 2,3,5-trimetyyli-6-nonyylisykloheksa-2,5-dieeni-1,4-dioni alfa-synukleinopatioiden, tauopatioiden ja muiden häiriöiden estämiseen ja hoitoon |
| CA3156499A1 (en) | 2019-10-04 | 2021-04-08 | Stealth Biotherapeutics Inc. | CHINONE, HYDROCHINONE AND NAPHTOCHINONE ANALOGS OF VATIQUINONE FOR THE TREATMENT OF DISEASES WITH MITOCHONDRIAL DISORDERS |
| JP2022552002A (ja) * | 2019-10-17 | 2022-12-14 | ザ・ペン・ステイト・リサーチ・ファウンデイション | 出血性脳卒中の治療のための機能的ニューロンの再生 |
| EP4126836A1 (en) | 2020-04-03 | 2023-02-08 | Stealth BioTherapeutics Inc. | Compositions and methods for the prevention and/or treatment of mitochondrial disease, including friedreich's ataxia |
| CN116762096A (zh) * | 2020-12-22 | 2023-09-15 | 皇家飞利浦有限公司 | 定位血管收缩 |
| CN113066113B (zh) * | 2021-04-27 | 2022-01-11 | 河北医科大学第二医院 | 自发性高血压大鼠脑模板和地图集的构建方法及设备 |
| CN118175991A (zh) | 2021-07-08 | 2024-06-11 | Ptc医疗公司 | 包含2,3,5-三甲基-6-壬基环己-2,5-二烯-1,4-二酮的药物组合物 |
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| EP2101808A4 (en) * | 2007-01-10 | 2011-11-30 | Edison Pharmaceuticals Inc | TREATMENT OF BREATHLY TROUBLES USING COMPOUNDS OF ERYTHROPOIETIN OR THROMBOPOIETIN ACTIVITY |
| SI3456707T1 (sl) * | 2007-11-06 | 2020-10-30 | Ptc Therapeutics, Inc. | Derivati 4-(P-kuinonil)-2-hidroksibutanamida za zdravljenje mitohondrijske bolezni |
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| JP5798481B2 (ja) * | 2008-06-25 | 2015-10-21 | エジソン ファーマシューティカルズ, インコーポレイテッド | 酸化ストレス疾患を治療するための2−ヘテロシクリルアミノアルキル−(p−キノン)誘導体 |
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| WO2010045220A1 (en) * | 2008-10-14 | 2010-04-22 | Edison Pharmaceuticals, Inc. | Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the function of red cells |
| MY157119A (en) * | 2008-10-28 | 2016-05-13 | Edison Pharmaceuticals Inc | Process for the production of alpha-tocotrienol and derivatives |
| HUE037574T2 (hu) * | 2009-04-28 | 2018-09-28 | Bioelectron Tech Corp | Leber-féle örökletes optikus neuropátia és domináns optikus atrofia kezelése tokotrienol kinonokkal |
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-
2010
- 2010-08-24 CA CA2772294A patent/CA2772294C/en active Active
- 2010-08-24 MX MX2012002374A patent/MX337990B/es active IP Right Grant
- 2010-08-24 WO PCT/US2010/046503 patent/WO2011025785A1/en not_active Ceased
- 2010-08-24 JP JP2012526918A patent/JP5785546B2/ja not_active Expired - Fee Related
- 2010-08-24 AU AU2010286704A patent/AU2010286704B2/en not_active Ceased
- 2010-08-24 ES ES10747777.0T patent/ES2663709T3/es active Active
- 2010-08-24 PT PT107477770T patent/PT2470168T/pt unknown
- 2010-08-24 CN CN201080048363.2A patent/CN102647981B/zh not_active Expired - Fee Related
- 2010-08-24 SI SI201031644T patent/SI2470168T1/en unknown
- 2010-08-24 DK DK10747777.0T patent/DK2470168T3/en active
- 2010-08-24 HU HUE10747777A patent/HUE037592T2/hu unknown
- 2010-08-24 US US12/862,705 patent/US20110207828A1/en not_active Abandoned
- 2010-08-24 PL PL10747777T patent/PL2470168T3/pl unknown
- 2010-08-24 EP EP10747777.0A patent/EP2470168B1/en active Active
- 2010-08-24 EA EA201200355A patent/EA028677B1/ru not_active IP Right Cessation
- 2010-08-24 NO NO10747777A patent/NO2470168T3/no unknown
- 2010-08-24 BR BR112012004167A patent/BR112012004167A2/pt not_active Application Discontinuation
-
2015
- 2015-02-16 JP JP2015027506A patent/JP2015091899A/ja active Pending
-
2016
- 2016-02-10 US US15/040,961 patent/US20170007553A1/en not_active Abandoned
-
2018
- 2018-08-09 US US16/100,062 patent/US20180344667A1/en not_active Abandoned
Also Published As
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|---|---|
| CN102647981A (zh) | 2012-08-22 |
| US20170007553A1 (en) | 2017-01-12 |
| EA028677B1 (ru) | 2017-12-29 |
| PL2470168T3 (pl) | 2018-06-29 |
| BR112012004167A2 (pt) | 2016-03-29 |
| PT2470168T (pt) | 2018-03-28 |
| JP2013503168A (ja) | 2013-01-31 |
| CN102647981B (zh) | 2016-09-28 |
| EP2470168B1 (en) | 2018-01-31 |
| SI2470168T1 (en) | 2018-05-31 |
| AU2010286704A1 (en) | 2012-03-22 |
| CA2772294C (en) | 2018-08-21 |
| NO2470168T3 (enExample) | 2018-06-30 |
| MX2012002374A (es) | 2012-04-10 |
| CA2772294A1 (en) | 2011-03-03 |
| HUE037592T2 (hu) | 2018-09-28 |
| EP2470168A1 (en) | 2012-07-04 |
| EA201200355A1 (ru) | 2012-07-30 |
| US20110207828A1 (en) | 2011-08-25 |
| US20180344667A1 (en) | 2018-12-06 |
| DK2470168T3 (en) | 2018-05-07 |
| JP5785546B2 (ja) | 2015-09-30 |
| WO2011025785A1 (en) | 2011-03-03 |
| ES2663709T3 (es) | 2018-04-16 |
| AU2010286704B2 (en) | 2016-10-20 |
| JP2015091899A (ja) | 2015-05-14 |
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