MX337593B - Gemcabeno y derivados para tratar la pancreatitis. - Google Patents
Gemcabeno y derivados para tratar la pancreatitis.Info
- Publication number
- MX337593B MX337593B MX2013007310A MX2013007310A MX337593B MX 337593 B MX337593 B MX 337593B MX 2013007310 A MX2013007310 A MX 2013007310A MX 2013007310 A MX2013007310 A MX 2013007310A MX 337593 B MX337593 B MX 337593B
- Authority
- MX
- Mexico
- Prior art keywords
- gemcabene
- derivatives
- treating pancreatitis
- pancreatitis
- free acid
- Prior art date
Links
- SDMBRCRVFFHJKR-UHFFFAOYSA-N 6-(5-carboxy-5-methylhexoxy)-2,2-dimethylhexanoic acid Chemical compound OC(=O)C(C)(C)CCCCOCCCCC(C)(C)C(O)=O SDMBRCRVFFHJKR-UHFFFAOYSA-N 0.000 title abstract 3
- 229950004781 gemcabene Drugs 0.000 title abstract 3
- 206010033645 Pancreatitis Diseases 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061427236P | 2010-12-27 | 2010-12-27 | |
| PCT/US2011/066736 WO2012092103A1 (en) | 2010-12-27 | 2011-12-22 | Gemcabene and derivatives for treating pancreatitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013007310A MX2013007310A (es) | 2013-10-25 |
| MX337593B true MX337593B (es) | 2016-03-11 |
Family
ID=45498140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013007310A MX337593B (es) | 2010-12-27 | 2011-12-22 | Gemcabeno y derivados para tratar la pancreatitis. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8846761B2 (enExample) |
| EP (2) | EP3170495B1 (enExample) |
| JP (3) | JP2014509305A (enExample) |
| CN (2) | CN103442707A (enExample) |
| AU (1) | AU2011352449B2 (enExample) |
| CA (1) | CA2822921C (enExample) |
| DK (1) | DK2658536T3 (enExample) |
| ES (1) | ES2608177T3 (enExample) |
| HK (1) | HK1250484A1 (enExample) |
| HU (1) | HUE031004T2 (enExample) |
| MX (1) | MX337593B (enExample) |
| PL (1) | PL2658536T3 (enExample) |
| PT (1) | PT2658536T (enExample) |
| WO (1) | WO2012092103A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201912713YA (en) | 2014-11-14 | 2020-02-27 | Gemphire Therapeutics Inc | PROCESSES AND INTERMEDIATES FOR PREPARING α,ω-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS |
| EP3370713A4 (en) * | 2015-11-06 | 2019-10-23 | Gemphire Therapeutics Inc. | TREATMENT OF MIXED DYSLIPIDEMIA |
| CA3059073A1 (en) | 2017-04-18 | 2018-10-25 | Gemphire Therapeutics Inc. | Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR900701262A (ko) * | 1988-06-06 | 1990-12-01 | 오까모도 쇼오스께 | 췌장염 등에 대한 치료제 |
| US5648387A (en) | 1995-03-24 | 1997-07-15 | Warner-Lambert Company | Carboxyalkylethers, formulations, and treatment of vascular diseases |
| US6861555B2 (en) | 2000-01-25 | 2005-03-01 | Warner-Lambert Company | Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith |
| US20020103252A1 (en) | 1997-12-12 | 2002-08-01 | Bisgaier Charles Larry | Statin-carboxyalkylether combinations |
| US20030105154A1 (en) * | 2001-10-24 | 2003-06-05 | Bisgaier Charles Larry | Statin-carboxyalkylether combinations |
| IL145712A0 (en) | 1999-04-01 | 2002-07-25 | Esperion Therapeutics Inc | Ether compounds, compositions, and uses thereof |
| US6713507B2 (en) | 2000-10-11 | 2004-03-30 | Esperion Therapeutics, Inc. | Ether compounds and compositions for cholesterol management and related uses |
| US6645170B2 (en) | 2001-03-05 | 2003-11-11 | Bioject Medical Technologies, Inc. | Simplified disposable needle-free injection apparatus and method |
| US20040229954A1 (en) * | 2003-05-16 | 2004-11-18 | Macdougall Diane Elaine | Selective manipulation of triglyceride, HDL and LDL parameters with 6-(5-carboxy-5-methyl-hexyloxy)-2,2-dimethylhexanoic acid monocalcium salt |
| US7345190B2 (en) | 2003-11-12 | 2008-03-18 | Ssv Therapeutics, Inc. | Carnitine conjugates as dual prodrugs and uses thereof |
-
2011
- 2011-12-22 EP EP16192597.9A patent/EP3170495B1/en active Active
- 2011-12-22 EP EP11810759.8A patent/EP2658536B1/en active Active
- 2011-12-22 PL PL11810759T patent/PL2658536T3/pl unknown
- 2011-12-22 PT PT118107598T patent/PT2658536T/pt unknown
- 2011-12-22 MX MX2013007310A patent/MX337593B/es active IP Right Grant
- 2011-12-22 WO PCT/US2011/066736 patent/WO2012092103A1/en not_active Ceased
- 2011-12-22 DK DK11810759.8T patent/DK2658536T3/en active
- 2011-12-22 CN CN2011800630388A patent/CN103442707A/zh active Pending
- 2011-12-22 CA CA2822921A patent/CA2822921C/en active Active
- 2011-12-22 CN CN201710858297.9A patent/CN107648210A/zh active Pending
- 2011-12-22 US US13/334,384 patent/US8846761B2/en active Active
- 2011-12-22 AU AU2011352449A patent/AU2011352449B2/en not_active Ceased
- 2011-12-22 HU HUE11810759A patent/HUE031004T2/en unknown
- 2011-12-22 JP JP2013546406A patent/JP2014509305A/ja not_active Withdrawn
- 2011-12-22 ES ES11810759.8T patent/ES2608177T3/es active Active
-
2015
- 2015-09-10 JP JP2015178843A patent/JP6207560B2/ja active Active
-
2017
- 2017-09-04 JP JP2017169145A patent/JP2018027953A/ja active Pending
-
2018
- 2018-08-01 HK HK18109899.3A patent/HK1250484A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016028075A (ja) | 2016-02-25 |
| WO2012092103A1 (en) | 2012-07-05 |
| JP6207560B2 (ja) | 2017-10-04 |
| HUE031004T2 (en) | 2017-06-28 |
| EP3170495A1 (en) | 2017-05-24 |
| JP2018027953A (ja) | 2018-02-22 |
| MX2013007310A (es) | 2013-10-25 |
| PT2658536T (pt) | 2016-12-22 |
| PL2658536T3 (pl) | 2017-04-28 |
| US8846761B2 (en) | 2014-09-30 |
| US20120165411A1 (en) | 2012-06-28 |
| CA2822921C (en) | 2018-07-17 |
| CA2822921A1 (en) | 2012-07-05 |
| CN103442707A (zh) | 2013-12-11 |
| EP2658536A1 (en) | 2013-11-06 |
| AU2011352449B2 (en) | 2015-06-18 |
| AU2011352449A1 (en) | 2013-07-11 |
| JP2014509305A (ja) | 2014-04-17 |
| EP2658536B1 (en) | 2016-10-19 |
| HK1250484A1 (zh) | 2018-12-21 |
| EP3170495B1 (en) | 2023-04-26 |
| ES2608177T3 (es) | 2017-04-06 |
| DK2658536T3 (en) | 2017-01-09 |
| CN107648210A (zh) | 2018-02-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |