MX3244E - Procedimiento mejorado para obtener una composicion efervescente de aspirina - Google Patents
Procedimiento mejorado para obtener una composicion efervescente de aspirinaInfo
- Publication number
- MX3244E MX3244E MX000545U MX54570U MX3244E MX 3244 E MX3244 E MX 3244E MX 000545 U MX000545 U MX 000545U MX 54570 U MX54570 U MX 54570U MX 3244 E MX3244 E MX 3244E
- Authority
- MX
- Mexico
- Prior art keywords
- aspirin
- suspension
- coating material
- aqueous solution
- surrounded
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a un procedimiento mejorado para obtener una composición efervescente de aspirina, de libre fluidez, fácilmente humedecible, en partículas, que comprende un núcleo de aspirina materailmente rodeado por una capa que contiene un material de revestimineto soluble en agua y farmacéuticamente aceptable, caracterizados por los pasos de: a) preparar una suspensión de aspirina en una solución acuosa que contiene un material de revestimiento con un punto de fusión de, por lo menos, 105 grados C, constituído por o que incluye al menos un ingrediente seleccionado de glicina, metionina, sacarosa, lactosa, un polímero de arabino-galactana, manitol, inositol, sorbitol; para la preparación de la suspensión se suspende la aspirina en una solución acuosa de un agente humectante y la suspensión resultante se convierte en una pasta suave mediante la adición de una primera porción de una cantidad de la solución acuosa del material del revestimiento y de un agente formador de película; el restante de la cantidad de solución se agrega a la pasta paa formar la suspensión, la cual se alimenta con agitación contínua a un dispositivo de rociado por aspersión, a una temperatura de entrada de entre 150 y 300 grados C; b) secar por aspersión la suspensión; los ingredientes en la suspensión están presentes en cantidades relativas tales que en el paso de secado por aspersión se forman partículas que comprenden un núcleo de aspirina materialmente rodeado por una capa del material de revestimiento.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB58203/69A GB1287475A (en) | 1969-11-28 | 1969-11-28 | Aspirin formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
MX3244E true MX3244E (es) | 1980-08-06 |
Family
ID=10481023
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX000545U MX3244E (es) | 1969-11-28 | 1970-11-27 | Procedimiento mejorado para obtener una composicion efervescente de aspirina |
Country Status (19)
Country | Link |
---|---|
US (1) | US3882228A (es) |
JP (1) | JPS516727B1 (es) |
AT (1) | AT302533B (es) |
BE (1) | BE759520A (es) |
CA (1) | CA948108A (es) |
DE (1) | DE2058434C3 (es) |
DK (1) | DK130453B (es) |
ES (1) | ES385974A1 (es) |
FR (1) | FR2073431B1 (es) |
GB (1) | GB1287475A (es) |
IE (1) | IE34756B1 (es) |
IL (1) | IL35714A (es) |
IN (1) | IN129401B (es) |
MX (1) | MX3244E (es) |
NL (1) | NL165928C (es) |
OA (1) | OA03600A (es) |
SE (1) | SE383099B (es) |
ZA (1) | ZA707915B (es) |
ZM (1) | ZM13470A1 (es) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2636152C2 (de) * | 1976-08-11 | 1980-11-06 | Arcana Chem.-Pharm. Fabrik Gmbh, Spittal, Drau (Oesterreich) | Verfahren zur Herstellung von Dragees |
JPS5364921A (en) * | 1976-11-24 | 1978-06-09 | Yasumi Aoki | Method of sliding snowfall on metal roof |
JPS5373831A (en) * | 1976-12-11 | 1978-06-30 | Keiichi Abe | Snow sliding roof |
US4251518A (en) * | 1979-07-03 | 1981-02-17 | Ralston Purina Company | Method of preparing readily disintegrable pharmaceutical compositions |
FR2470599A1 (fr) * | 1979-12-07 | 1981-06-12 | Panoz Donald | Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus |
JPS58110745A (ja) * | 1981-12-22 | 1983-07-01 | 株式会社西部技研 | 屋根の積雪防止装置 |
FR2525474A1 (fr) * | 1982-04-26 | 1983-10-28 | Roussel Uclaf | Nouvelle forme pharmaceutique orale de clometacine |
US4459280A (en) * | 1982-07-23 | 1984-07-10 | G. D. Searle & Co. | Psyllium hydrophilic mucilloid composition |
US4548806A (en) * | 1982-07-23 | 1985-10-22 | G. D. Searle & Co. | Psyllium hydrophilic mucilloid composition |
US4507276A (en) * | 1982-08-20 | 1985-03-26 | Bristol-Myers Company | Analgesic capsule |
JPS60100516A (ja) * | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
US4568559A (en) * | 1984-02-06 | 1986-02-04 | Biotek, Inc. | Composite core coated microparticles and process of preparing same |
JPS6152012U (es) * | 1984-09-12 | 1986-04-08 | ||
DE3440288C2 (de) * | 1984-11-05 | 1987-03-12 | Gergely, Gerhard, Dr.-Ing., Wien | Pharmazeutische Zubereitung mit einem Gehalt an Ibuprofen sowie Verfahren zu ihrer Herstellung |
US4867984A (en) * | 1984-11-06 | 1989-09-19 | Nagin K. Patel | Drug in bead form and process for preparing same |
IE59106B1 (en) * | 1985-05-31 | 1994-01-12 | Warner Lambert Co | A therapeutic effervescent composition and a method of preparing the same |
US4687662A (en) * | 1985-08-30 | 1987-08-18 | Warner-Lambert Company | Therapeutic effervescent composition |
US4650669A (en) * | 1985-07-30 | 1987-03-17 | Miles Laboratories, Inc. | Method to make effervescent calcium tablets and calcium tablets produced thereby |
US5188840A (en) * | 1985-09-26 | 1993-02-23 | Chugai Seiyaku Kabushiki Kaisha | Slow-release pharmaceutical agent |
GB8525348D0 (en) * | 1985-10-15 | 1985-11-20 | Nicholas Kiwi Pacific Pty Ltd | Effervescent tablets |
US5238686A (en) * | 1986-03-27 | 1993-08-24 | Kinaform Technology, Inc. | Sustained-release pharmaceutical preparation |
US5223264A (en) * | 1989-10-02 | 1993-06-29 | Cima Labs, Inc. | Pediatric effervescent dosage form |
DE4027927A1 (de) * | 1990-09-04 | 1992-03-05 | Bayer Ag | Brausekomponente und verfahren zu ihrer herstellung |
US5085852A (en) * | 1991-04-19 | 1992-02-04 | The Procter & Gamble Company | Antimicrobial oral compositions |
ATE154241T1 (de) * | 1991-10-01 | 1997-06-15 | Takeda Chemical Industries Ltd | Mikropartikeln-zusammenfassung zur verlängerten freigabe und herstellung derselbe |
TW333456B (en) | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
HU217125B (hu) * | 1993-03-10 | 1999-11-29 | Béres Rt. | Cukor- és nátriummentes pezsgőtabletta és -granulátum és eljárás azok előállítására |
FR2708853A1 (fr) * | 1993-06-30 | 1995-02-17 | Salsarulo Gilles | Composition à base d'acide acétylsalicylique à biodisponibilité améliorée et procédé pour la produire. |
DE19606151C2 (de) | 1996-02-20 | 1999-05-12 | Losan Pharma Gmbh | Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben |
US6248391B1 (en) * | 1997-07-16 | 2001-06-19 | Bpsi Holdings, Inc. | Bright white film coatings and film coating compositions therefor |
FR2766089B1 (fr) * | 1997-07-21 | 2000-06-02 | Prographarm Lab | Comprime multiparticulaire perfectionne a delitement rapide |
EP0913178A1 (en) * | 1997-11-03 | 1999-05-06 | Boehringer Mannheim Gmbh | Process for the manufacture of dry, amorphous products comprising biologically active material by means of convection drying and products obtainable by the process |
EP0913177A1 (de) * | 1997-11-03 | 1999-05-06 | Roche Diagnostics GmbH | Verfahren zur Herstellung trockener, amorpher Produkte enthaltend biologisch aktive Materialien mittels Konvektionstrocknung, insbesondere Sprühtrocknung |
US20070141181A1 (en) | 1998-02-13 | 2007-06-21 | Nutramax Laboratories, Inc. | Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals |
US6797289B2 (en) | 1998-02-13 | 2004-09-28 | Nutramax Laboratories, Inc. | Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals |
US20010000472A1 (en) * | 1998-02-27 | 2001-04-26 | Nutramax Laboratories, Inc. | L-ergothioneine, milk thistle, and s-adenosylmethionine for the prevention, treatment and repair of liver damage |
AU3308999A (en) | 1998-02-27 | 1999-09-15 | Nutramax Laboratories, Inc. | L-ergothioneine, milk thistle, and s-adenosylmethionine for the prevention, treatment and repair of liver damage |
US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
AU2003209475A1 (en) * | 2002-03-07 | 2003-09-16 | Vectura Limited | Fast melt multiparticulate formulations for oral delivery |
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US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
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NZ540166A (en) | 2002-10-25 | 2007-06-29 | Foamix Ltd | Cosmetic and pharmaceutical foam |
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US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
US8119109B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Foamable compositions, kits and methods for hyperhidrosis |
US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
US8119150B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Non-flammable insecticide composition and uses thereof |
US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
CA2555121A1 (en) * | 2004-02-04 | 2005-08-25 | Foamix Ltd. | Cosmetic and pharmaceutical foam with solid matter |
AU2006313443A1 (en) * | 2005-05-09 | 2007-05-18 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
AU2006271230A1 (en) | 2005-07-22 | 2007-01-25 | Warner Chilcott Company, Llc | Compositions for reducing the incidence of drug induced arrhythmia |
EP1757274B1 (de) * | 2005-08-08 | 2012-07-25 | Stada Arzneimittel Ag | Brausezubereitung gegen Erkältungssymptome |
CN101489414B (zh) * | 2006-07-12 | 2013-05-22 | 普拉克生化公司 | 部分中和的酸涂层的食品级颗粒 |
US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
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SG173537A1 (en) | 2009-04-01 | 2011-09-29 | Colgate Palmolive Co | Dentifrice compositions and methods for treating and preventing damage to tooth surfaces |
WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
CA2769625C (en) | 2009-07-29 | 2017-04-11 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
US8945516B2 (en) | 2009-10-02 | 2015-02-03 | Foamix Pharmaceuticals Ltd. | Surfactant-free water-free foamable compositions, breakable foams and gels and their uses |
US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
WO2011143347A2 (en) * | 2010-05-11 | 2011-11-17 | Sensient Colors Llc | Film coating composition and methods of making and using the same |
US8900557B2 (en) | 2010-12-30 | 2014-12-02 | Jr Chem, Llc | Dental cleaning composition |
MX369634B (es) * | 2015-02-20 | 2019-11-14 | Cytec Ind Inc | Composiciones de dialquil sulfosuccinato, metodos para hacerlas y metodos de uso. |
US10398641B2 (en) | 2016-09-08 | 2019-09-03 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
CA3178769A1 (en) | 2020-05-18 | 2021-11-25 | Jonas Savmarker | New pharmaceutical composition for drug delivery |
EP4236921A1 (en) | 2021-11-25 | 2023-09-06 | Orexo AB | Pharmaceutical composition comprising adrenaline |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1299504A (fr) * | 1959-04-15 | 1962-07-27 | Philips Nv | Procédé de préparation de produits secs pour poudrage, stables à l'air, contenant en particulier des substances douées d'activité biologique |
US3145146A (en) * | 1961-10-31 | 1964-08-18 | Warner Lambert Pharmaceutical | Modified mannitol for pharmaceutical tablets |
US3293132A (en) * | 1963-03-25 | 1966-12-20 | Merck & Co Inc | Spray dried vitamin compositions and method of preparation |
NL6414091A (nl) * | 1964-12-04 | 1966-06-06 | Organon Nv | Werkwijze voor het vloeibaar maken van poeders alsmede de aldus verkregen poeders |
US3384546A (en) * | 1965-05-28 | 1968-05-21 | Miles Lab | Directly compressed low-density crystalline sorbitol pharmaceutical tablets |
-
0
- BE BE759520D patent/BE759520A/xx not_active IP Right Cessation
-
1969
- 1969-11-28 GB GB58203/69A patent/GB1287475A/en not_active Expired
-
1970
- 1970-11-23 US US092284A patent/US3882228A/en not_active Expired - Lifetime
- 1970-11-23 IE IE1499/70A patent/IE34756B1/xx unknown
- 1970-11-23 ZA ZA707915A patent/ZA707915B/xx unknown
- 1970-11-24 IL IL35714A patent/IL35714A/xx unknown
- 1970-11-26 IN IN129401A patent/IN129401B/en unknown
- 1970-11-27 FR FR7042668A patent/FR2073431B1/fr not_active Expired
- 1970-11-27 ZM ZM134/70A patent/ZM13470A1/xx unknown
- 1970-11-27 SE SE7016129A patent/SE383099B/xx unknown
- 1970-11-27 DE DE2058434A patent/DE2058434C3/de not_active Expired
- 1970-11-27 AT AT1071370A patent/AT302533B/de not_active IP Right Cessation
- 1970-11-27 OA OA54102A patent/OA03600A/xx unknown
- 1970-11-27 ES ES385974A patent/ES385974A1/es not_active Expired
- 1970-11-27 NL NL7017417.A patent/NL165928C/xx not_active IP Right Cessation
- 1970-11-27 MX MX000545U patent/MX3244E/es unknown
- 1970-11-27 CA CA099,296A patent/CA948108A/en not_active Expired
- 1970-11-27 DK DK605470AA patent/DK130453B/da not_active IP Right Cessation
- 1970-11-28 JP JP45105390A patent/JPS516727B1/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
BE759520A (fr) | 1971-04-30 |
NL7017417A (es) | 1971-06-02 |
IL35714A0 (en) | 1971-01-28 |
ES385974A1 (es) | 1973-05-01 |
DE2058434B2 (de) | 1980-04-24 |
OA03600A (fr) | 1971-03-30 |
AT302533B (de) | 1972-10-25 |
SE383099B (sv) | 1976-03-01 |
ZA707915B (en) | 1971-08-25 |
FR2073431B1 (es) | 1974-03-22 |
IN129401B (es) | 1975-08-16 |
FR2073431A1 (es) | 1971-10-01 |
DK130453B (da) | 1975-02-24 |
US3882228A (en) | 1975-05-06 |
IE34756B1 (en) | 1975-08-06 |
DE2058434A1 (de) | 1971-06-03 |
CA948108A (en) | 1974-05-28 |
ZM13470A1 (en) | 1971-11-22 |
GB1287475A (en) | 1972-08-31 |
NL165928B (nl) | 1981-01-15 |
DE2058434C3 (de) | 1980-12-18 |
IE34756L (en) | 1971-05-28 |
NL165928C (nl) | 1981-06-15 |
JPS516727B1 (es) | 1976-03-02 |
DK130453C (es) | 1975-07-21 |
IL35714A (en) | 1974-03-14 |
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