SE401364B - Forfarande for framstellning av i stellningen 16 alkylerade prostaglandinanaloger av typ pgfŸ2 - Google Patents

Forfarande for framstellning av i stellningen 16 alkylerade prostaglandinanaloger av typ pgfŸ2

Info

Publication number
SE401364B
SE401364B SE7204588A SE458872A SE401364B SE 401364 B SE401364 B SE 401364B SE 7204588 A SE7204588 A SE 7204588A SE 458872 A SE458872 A SE 458872A SE 401364 B SE401364 B SE 401364B
Authority
SE
Sweden
Prior art keywords
pgfÿ2
prostagland
alkylated
analogs
preparing
Prior art date
Application number
SE7204588A
Other languages
English (en)
Inventor
B J Magerlein
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of SE401364B publication Critical patent/SE401364B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
SE7204588A 1971-04-12 1972-04-10 Forfarande for framstellning av i stellningen 16 alkylerade prostaglandinanaloger av typ pgfŸ2 SE401364B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13334271A 1971-04-12 1971-04-12
US05/555,780 US4212811A (en) 1971-04-12 1975-03-06 Bicyclic lactone intermediates

Publications (1)

Publication Number Publication Date
SE401364B true SE401364B (sv) 1978-05-02

Family

ID=26831285

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7204588A SE401364B (sv) 1971-04-12 1972-04-10 Forfarande for framstellning av i stellningen 16 alkylerade prostaglandinanaloger av typ pgfŸ2
SE7506373A SE401365B (sv) 1971-04-12 1975-06-04 Forfarande for framstellning av i stellningen 16 alkylerade prostaglendinanaloger av typ pgfŸ2
SE7700095A SE418289B (sv) 1971-04-12 1977-01-05 16-alkylerade prostaglandiner av typ pgf?712alfa till anvendning som medel for reglering av reproduktionscykeln

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE7506373A SE401365B (sv) 1971-04-12 1975-06-04 Forfarande for framstellning av i stellningen 16 alkylerade prostaglendinanaloger av typ pgfŸ2
SE7700095A SE418289B (sv) 1971-04-12 1977-01-05 16-alkylerade prostaglandiner av typ pgf?712alfa till anvendning som medel for reglering av reproduktionscykeln

Country Status (10)

Country Link
US (1) US4212811A (sv)
JP (2) JPS5069063A (sv)
BE (1) BE781979A (sv)
CA (1) CA984387A (sv)
CH (2) CH573384A5 (sv)
DE (1) DE2217044C2 (sv)
FR (1) FR2132859B1 (sv)
GB (2) GB1392991A (sv)
NL (1) NL163507C (sv)
SE (3) SE401364B (sv)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1060007A (en) * 1975-02-18 1979-08-07 Gilbert A. Youngdale 2a,2b-dihomo-16,16-dimethyl-prostaglandin analogs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (sv) * 1970-06-10 1975-02-04
US3901923A (en) * 1971-03-23 1975-08-26 Upjohn Co Acylated bicyclic lactones
US3778450A (en) * 1971-03-23 1973-12-11 Upjohn Co Certain bicyclic lactones

Also Published As

Publication number Publication date
CH573384A5 (sv) 1976-03-15
DE2217044A1 (de) 1972-10-26
BE781979A (fr) 1972-10-12
JPS562063B2 (sv) 1981-01-17
GB1392991A (en) 1975-05-07
DE2217044C2 (de) 1985-07-11
SE7506373L (sv) 1975-06-04
NL7204869A (sv) 1972-10-16
JPS5069050A (sv) 1975-06-09
SE401365B (sv) 1978-05-02
FR2132859B1 (sv) 1976-04-16
CA984387A (en) 1976-02-24
GB1392992A (en) 1975-05-07
SE418289B (sv) 1981-05-18
JPS5069063A (sv) 1975-06-09
FR2132859A1 (sv) 1972-11-24
US4212811A (en) 1980-07-15
NL163507C (nl) 1980-09-15
SE7700095L (sv) 1977-01-05
CH573887A5 (sv) 1976-03-31
NL163507B (nl) 1980-04-15

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