MX2023004618A - Uso de formulaciones de coenzima q10 en el tratamiento y prevencion de epidermolisis ampollosa. - Google Patents

Uso de formulaciones de coenzima q10 en el tratamiento y prevencion de epidermolisis ampollosa.

Info

Publication number
MX2023004618A
MX2023004618A MX2023004618A MX2023004618A MX2023004618A MX 2023004618 A MX2023004618 A MX 2023004618A MX 2023004618 A MX2023004618 A MX 2023004618A MX 2023004618 A MX2023004618 A MX 2023004618A MX 2023004618 A MX2023004618 A MX 2023004618A
Authority
MX
Mexico
Prior art keywords
coenzyme
epidermolysis bullosa
formulations
prevention
treatment
Prior art date
Application number
MX2023004618A
Other languages
English (en)
Inventor
Rangaprasad Sarangarajan
Niven Rajin Narain
Michael Andrew Kiebish
Original Assignee
Berg Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berg Llc filed Critical Berg Llc
Publication of MX2023004618A publication Critical patent/MX2023004618A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere, en parte, a métodos para tratar Epidermólisis Ampollosa (EB, por sus siglas en inglés) en un sujeto en necesidad del mismo, caracterizada porque comprende la administración tópica de una cantidad terapéuticamente efectiva de una Coenzima Q10 (CoQ10, por sus siglas en inglés) al sujeto.
MX2023004618A 2017-05-17 2019-11-15 Uso de formulaciones de coenzima q10 en el tratamiento y prevencion de epidermolisis ampollosa. MX2023004618A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762507773P 2017-05-17 2017-05-17

Publications (1)

Publication Number Publication Date
MX2023004618A true MX2023004618A (es) 2023-05-09

Family

ID=64274898

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023004618A MX2023004618A (es) 2017-05-17 2019-11-15 Uso de formulaciones de coenzima q10 en el tratamiento y prevencion de epidermolisis ampollosa.

Country Status (12)

Country Link
US (2) US11419830B2 (es)
EP (1) EP3634391A4 (es)
JP (1) JP7173992B2 (es)
KR (1) KR102682716B1 (es)
CN (1) CN110769818A (es)
AU (1) AU2018269377A1 (es)
BR (1) BR112019024116A2 (es)
CA (1) CA3063916A1 (es)
CL (1) CL2019003287A1 (es)
MA (1) MA52274A (es)
MX (1) MX2023004618A (es)
WO (1) WO2018213502A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210116531A (ko) * 2019-01-18 2021-09-27 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 영양 장애형 표피 수포증 치료약
WO2023064806A1 (en) 2021-10-12 2023-04-20 Phoenix Tissue Repair, Inc. Collagen 7 protein replacement therapy

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS588010A (ja) 1981-07-08 1983-01-18 Eisai Co Ltd ユビデカレノン含有リポソ−ム
JPS58201711A (ja) 1982-05-19 1983-11-24 Eisai Co Ltd ユビデカレノン含有リポソ−ム被覆体
US4895727A (en) 1985-05-03 1990-01-23 Chemex Pharmaceuticals, Inc. Pharmaceutical vehicles for exhancing penetration and retention in the skin
JPS6277318A (ja) 1985-10-01 1987-04-09 Eisai Co Ltd 熱傷治療剤
JPS6339813A (ja) 1986-08-05 1988-02-20 Eisai Co Ltd 創傷治療剤
US6764693B1 (en) 1992-12-11 2004-07-20 Amaox, Ltd. Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants
US5863556A (en) 1993-08-20 1999-01-26 Euro-Celtique, S.A. Preparations for the external application of antiseptic agents and/or agents promoting the healing of wounds
PT789584E (pt) 1994-11-04 2002-03-28 Polymun Scient Immunbio Forsch Aplicacao de superoxido-dismutase (sod) em liposomas
IL117773A (en) 1996-04-02 2000-10-31 Pharmos Ltd Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability
US5891469A (en) 1997-04-02 1999-04-06 Pharmos Corporation Solid Coprecipitates for enhanced bioavailability of lipophilic substances
WO1999011242A1 (en) 1997-09-04 1999-03-11 Biozone Laboratories, Inc. Oral liposomal delivery system
US6048846A (en) 1998-02-26 2000-04-11 Cochran; Timothy M. Compositions used in human treatment
US20040170625A1 (en) * 1998-07-30 2004-09-02 Regenerx Biopharmaceuticals, Inc. Methods of treating Epidermolysis Bullosa and associated dermatological indications with thymosin beta 4, analogues, isoforms and other derivatives
US20040034107A1 (en) 1999-02-11 2004-02-19 Mse Pharmazeutika Gmbh Ubiquinone Qn for the treatment of pain
DE19905879A1 (de) 1999-02-11 2000-08-17 Mse Pharmazeutika Gmbh Ubichinon Qn zur Behandlung von Schmerzen
US20050019268A1 (en) 1999-02-11 2005-01-27 Mse Pharmazeutika Gmbh Spray containing ubiquinone Qn
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
AU3930600A (en) * 1999-03-30 2000-10-16 Purdue Research Foundation Methods for identifying agents that inhibit serum aging factors and uses and compositions thereof
US20020048551A1 (en) 1999-04-06 2002-04-25 Keller Brian C. Delivery of biologically active material in a liposomal formulation for administration into the mouth
US7005274B1 (en) 1999-09-15 2006-02-28 Migenix Corp. Methods and compositions for diagnosing and treating arthritic disorders and regulating bone mass
IT1307281B1 (it) 1999-11-25 2001-10-30 Simonelli Giuseppe Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva,
NZ509803A (en) 2000-02-09 2001-08-31 Paul A Treatment of fibromyalgia with ubiquinone 10 and succinic acid
EP1278512A2 (en) 2000-05-03 2003-01-29 MBT Munich Biotechnology AG Cationic diagnostic, imaging and therapeutic agents associated with activated vascular sites
ATE402692T1 (de) * 2000-05-09 2008-08-15 Kaneka Corp Dermale zusammenstellungen die als wirkstoff coenzym q enthalten
US6465517B1 (en) 2000-07-11 2002-10-15 N.V. Nutricia Composition for the treatment of migraine
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
AUPR177300A0 (en) 2000-11-29 2000-12-21 Centre For Molecular Biology And Medicine Therapeutic methods
US6984395B2 (en) 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
EP1388340B1 (en) 2001-05-10 2010-09-08 Kaneka Corporation Compositions for transmucosal administration containing coenzyme q as the active ingredient
WO2002096408A1 (en) 2001-05-30 2002-12-05 Laxdale Limited Coenzyme q and eicosapentaenoic acid (epa)
US6753325B2 (en) 2001-11-06 2004-06-22 The Quigley Corporation Composition and method for prevention, reduction and treatment of radiation dermatitis
US20030105031A1 (en) 2001-11-06 2003-06-05 Rosenbloom Richard A. Methods for the treatment of skin disorders
US20030118536A1 (en) 2001-11-06 2003-06-26 Rosenbloom Richard A. Topical compositions and methods for treatment of adverse effects of ionizing radiation
US20030105027A1 (en) 2001-11-06 2003-06-05 Rosenbloom Richard A. Nutritional supplements and methods for prevention, reduction and treatment of radiation injury
US7435725B2 (en) 2001-11-06 2008-10-14 The Quigly Corporation Oral compositions and methods for prevention, reduction and treatment of radiation injury
US9034310B2 (en) 2002-02-21 2015-05-19 Stephen B. Cantrell Interferon-statin combination cancer therapy
AU2003218718A1 (en) 2002-03-09 2003-09-22 Mse Pharmazeutika Gmbh Utilization of ubiquinones for influencing the effect of histamine
US7060733B2 (en) 2002-08-15 2006-06-13 The Regents Of The University Of California Methods for treating pancreatitis with curcumin compounds and inhibitors of reactive oxygen species
US7083813B2 (en) 2002-11-06 2006-08-01 The Quigley Corporation Methods for the treatment of peripheral neural and vascular ailments
TWI322008B (en) 2003-01-31 2010-03-21 Kaneka Corp Fatigue improving agent including reduced coenzyme q10
CN1208052C (zh) 2003-03-20 2005-06-29 上海家化联合股份有限公司 一种辅酶q10前体脂质体及其制备方法
US8252322B2 (en) 2003-06-03 2012-08-28 Corn Products Development, Inc. Delivery system with increased bioavailability
AU2004251774A1 (en) 2003-06-25 2005-01-06 Charles Erwin Chemical combination and method for increasing delivery of coenzyme Q 10
US7169385B2 (en) 2003-09-29 2007-01-30 Ronald G. Udell Solubilized CoQ-10 and carnitine
US20070009583A1 (en) 2003-10-10 2007-01-11 Qvist Michael H Dressing
ME01881B (me) 2004-01-22 2014-12-20 Univ Miami Topijske formulacije koenzima q10 i postupci upotrebe
US20050226947A1 (en) * 2004-02-04 2005-10-13 Dale Kern Agents for sequestering serum aging factors and uses therefore
US20050208118A1 (en) 2004-03-18 2005-09-22 Takemoto Arnold C Preparations of encapsulated bioavailable chelating agents for detoxifying humans and animals
US20090098201A1 (en) 2004-06-28 2009-04-16 Bio Intellectual Property Services (Bio Ips) Llc Composition and Method for Treatment and Prevention of Atherosclerosis
US20060110415A1 (en) 2004-11-22 2006-05-25 Bioderm Research Topical Delivery System for Cosmetic and Pharmaceutical Agents
EP1909763A2 (en) 2005-07-28 2008-04-16 Isp Investments Inc. Benzoquinones of enhanced bioavailability
JP2007063160A (ja) * 2005-08-30 2007-03-15 Shiseido Co Ltd 基底膜安定化剤
JP4794289B2 (ja) 2005-12-07 2011-10-19 株式会社村田製作所 カード型装置
US10583098B2 (en) 2006-05-02 2020-03-10 Sung Lan Hsia Topical co-enzyme Q10 formulations and treatment of pain, fatigue and wounds
EP2136787B1 (en) 2007-03-22 2019-08-21 Berg LLC Topical formulations having enhanced bioavailability
JP2009040757A (ja) * 2007-08-10 2009-02-26 Maruzen Pharmaceut Co Ltd ラミニン５産生促進剤、皮膚基底膜正常化剤及び皮膚損傷回復促進剤
JP2009191039A (ja) * 2008-02-15 2009-08-27 Maruzen Pharmaceut Co Ltd ヒアルロン酸合成酵素３ｍＲＮＡ発現促進剤、アクアポリン３ｍＲＮＡ発現促進剤、セリンパルミトイルトランスフェラーゼｍＲＮＡ発現促進剤及びラミニン５産生促進剤
EA034552B1 (ru) 2009-05-11 2020-02-19 БЕРГ ЭлЭлСи Способ лечения или предотвращения прогрессирования онкологических заболеваний
CN102548549A (zh) * 2009-08-25 2012-07-04 细胞研究有限公司 利用外代谢转换剂(辅酶q10)治疗肉瘤的方法
PE20130045A1 (es) 2010-03-12 2013-01-28 Berg Pharma Llc FORMULACIONES INTRAVENOSAS DE COENZIMA Q10 (CoQ10) Y METODOS DE USO DE LAS MISMAS
AU2011350620B2 (en) 2010-12-28 2017-03-02 Kamedis Ltd. Plant extracts for the treatment and prevention of infections
US9211256B2 (en) 2011-03-08 2015-12-15 The Johns Hopkins University Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof
KR102058256B1 (ko) 2011-06-17 2020-01-22 버그 엘엘씨 흡입성 약제학적 조성물들
NZ702369A (en) * 2012-06-01 2016-12-23 Berg Llc Treatment of solid tumors using coenzyme q10
US10960045B2 (en) 2015-10-14 2021-03-30 Constant Therapeutics Llc Methods and compositions for the treatment of epidermolysis bullosa

Also Published As

Publication number Publication date
EP3634391A1 (en) 2020-04-15
CL2019003287A1 (es) 2020-07-31
US11419830B2 (en) 2022-08-23
KR20200015549A (ko) 2020-02-12
WO2018213502A1 (en) 2018-11-22
CN110769818A (zh) 2020-02-07
EP3634391A4 (en) 2021-02-24
BR112019024116A2 (pt) 2020-06-02
MA52274A (fr) 2021-02-24
US20180369164A1 (en) 2018-12-27
AU2018269377A1 (en) 2019-12-19
JP7173992B2 (ja) 2022-11-17
US20230142060A1 (en) 2023-05-11
JP2020520927A (ja) 2020-07-16
CA3063916A1 (en) 2018-11-22
KR102682716B1 (ko) 2024-07-08

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