MX2023002896A - Metodo para monitoreo no invasivo de agente trazador fluorescente con correcciones de reflejo difuso. - Google Patents

Metodo para monitoreo no invasivo de agente trazador fluorescente con correcciones de reflejo difuso.

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Publication number
MX2023002896A
MX2023002896A MX2023002896A MX2023002896A MX2023002896A MX 2023002896 A MX2023002896 A MX 2023002896A MX 2023002896 A MX2023002896 A MX 2023002896A MX 2023002896 A MX2023002896 A MX 2023002896A MX 2023002896 A MX2023002896 A MX 2023002896A
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Mexico
Prior art keywords
sub
signal
detector during
during illumination
fluorescent agent
Prior art date
Application number
MX2023002896A
Other languages
English (en)
Inventor
Edward Solomon
Jennifer Keating
Kimberly Schultz
Kate Bechtel
Original Assignee
Medibeacon Inc
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Publication date
Application filed by Medibeacon Inc filed Critical Medibeacon Inc
Publication of MX2023002896A publication Critical patent/MX2023002896A/es

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    • A61B5/201—Assessing renal or kidney functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14556—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases by fluorescence
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    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physiology (AREA)
  • Signal Processing (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Optics & Photonics (AREA)
  • Evolutionary Computation (AREA)
  • Fuzzy Systems (AREA)
  • Mathematical Physics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Un método para monitorear una señal de fluorescencia de tiempo variable emitida de un agente fluorescente desde dentro de un medio con propiedades ópticas de tiempo variable se proporciona e incluye proporcionar un conjunto de datos de medición que incluye una pluralidad de entradas de medición que incluyen al menos dos mediciones obtenidas de un paciente antes y después de administración del agente fluorescente. Las mediciones pueden incluir uno o más de: una señal DRex detectada por un detector de luz no filtrado durante iluminación por luz de longitud de onda de excitación de la primera región adyacente al medio de reflejo difuso; una señal de Flr detectada por un detector de luz filtrado durante iluminación por luz de longitud de onda de excitación; y una señal DRem detectada por el detector de luz no filtrado durante iluminación por luz de longitud de onda de emisión. El método además incluye identificar una porción de administración de pos-agente del conjunto de datos de medición; y transformar cada señal de Flr a una señal IF que representa una intensidad de fluorescencia detectada emitida únicamente por el agente fluorescente.
MX2023002896A 2017-01-30 2019-07-30 Metodo para monitoreo no invasivo de agente trazador fluorescente con correcciones de reflejo difuso. MX2023002896A (es)

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US201762452025P 2017-01-30 2017-01-30

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MX2019009040A MX2019009040A (es) 2017-01-30 2018-01-30 Metodo para monitoreo no invasivo de agente trazador fluorescente con correcciones de reflejo difuso.
MX2023002896A MX2023002896A (es) 2017-01-30 2019-07-30 Metodo para monitoreo no invasivo de agente trazador fluorescente con correcciones de reflejo difuso.

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US (6) US10548521B2 (es)
EP (1) EP3573518A4 (es)
JP (2) JP6861288B2 (es)
KR (2) KR102429632B1 (es)
CN (3) CN110520035B (es)
AU (1) AU2018213422B2 (es)
BR (1) BR112019015520A2 (es)
CA (2) CA3051963A1 (es)
IL (2) IL300236B2 (es)
MX (2) MX2019009040A (es)
PH (1) PH12019501749A1 (es)
RU (1) RU2721652C1 (es)
SG (2) SG10202108183SA (es)
WO (1) WO2018140978A1 (es)
ZA (1) ZA201904973B (es)

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