MX2023001194A - Inhibidores de la endonucleasa policiclicos dependientes de la capside para el tratamiento o la prevencion de la influenza. - Google Patents
Inhibidores de la endonucleasa policiclicos dependientes de la capside para el tratamiento o la prevencion de la influenza.Info
- Publication number
- MX2023001194A MX2023001194A MX2023001194A MX2023001194A MX2023001194A MX 2023001194 A MX2023001194 A MX 2023001194A MX 2023001194 A MX2023001194 A MX 2023001194A MX 2023001194 A MX2023001194 A MX 2023001194A MX 2023001194 A MX2023001194 A MX 2023001194A
- Authority
- MX
- Mexico
- Prior art keywords
- cap
- treating
- polycyclic
- preventing influenza
- dependent endonuclease
- Prior art date
Links
- 102000004533 Endonucleases Human genes 0.000 title abstract 2
- 108010042407 Endonucleases Proteins 0.000 title abstract 2
- 230000001419 dependent effect Effects 0.000 title abstract 2
- 206010022000 influenza Diseases 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 125000003367 polycyclic group Chemical group 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063056861P | 2020-07-27 | 2020-07-27 | |
| PCT/US2021/042711 WO2022026285A1 (en) | 2020-07-27 | 2021-07-22 | Polycyclic cap-dependent endonuclease inhibitors for treating or preventing influenza |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023001194A true MX2023001194A (es) | 2023-04-20 |
Family
ID=80038102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023001194A MX2023001194A (es) | 2020-07-27 | 2021-07-22 | Inhibidores de la endonucleasa policiclicos dependientes de la capside para el tratamiento o la prevencion de la influenza. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240018145A1 (enExample) |
| EP (1) | EP4188379B1 (enExample) |
| JP (1) | JP7695339B2 (enExample) |
| KR (1) | KR20230044252A (enExample) |
| CN (1) | CN116490190A (enExample) |
| AU (1) | AU2021315475A1 (enExample) |
| BR (1) | BR112023001325A2 (enExample) |
| CA (1) | CA3187516A1 (enExample) |
| MX (1) | MX2023001194A (enExample) |
| WO (1) | WO2022026285A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250154090A1 (en) * | 2022-03-01 | 2025-05-15 | Firmenich Sa | Process for preparing gamma,delta-unsaturated aldehydes derivatives |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5475109A (en) * | 1994-10-17 | 1995-12-12 | Merck & Co., Inc. | Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease |
| MX2008005137A (es) * | 2005-10-27 | 2008-09-29 | Shionogi & Co | Derivado de carbamoilpiridona policiclica que tiene actividad inhibidora en vih integrasa. |
| DK2620436T3 (en) * | 2010-09-24 | 2018-07-30 | Shionogi & Co | Substituted polycyclic carbamoylpyridone derivative prodrug |
| TWI695003B (zh) * | 2014-12-23 | 2020-06-01 | 美商基利科學股份有限公司 | 多環胺甲醯基吡啶酮化合物及其醫藥用途 |
| EP4257137A3 (en) * | 2018-05-31 | 2023-11-01 | Shionogi & Co., Ltd | Polycyclic carbamoylpyridone derivatives for the treatment of hiv |
| MA52802A (fr) * | 2018-05-31 | 2021-04-14 | Shionogi & Co | Dérivé de pyridone polycyclique |
| WO2020055858A1 (en) * | 2018-09-10 | 2020-03-19 | Cocrystal Pharma, Inc. | Pyridopyrazine and pyridotriazine inhibitors of influenza virus replication |
-
2021
- 2021-07-22 US US18/015,465 patent/US20240018145A1/en active Pending
- 2021-07-22 CA CA3187516A patent/CA3187516A1/en active Pending
- 2021-07-22 KR KR1020237006229A patent/KR20230044252A/ko active Pending
- 2021-07-22 CN CN202180065598.0A patent/CN116490190A/zh active Pending
- 2021-07-22 JP JP2023505421A patent/JP7695339B2/ja active Active
- 2021-07-22 WO PCT/US2021/042711 patent/WO2022026285A1/en not_active Ceased
- 2021-07-22 MX MX2023001194A patent/MX2023001194A/es unknown
- 2021-07-22 EP EP21848925.0A patent/EP4188379B1/en active Active
- 2021-07-22 BR BR112023001325A patent/BR112023001325A2/pt unknown
- 2021-07-22 AU AU2021315475A patent/AU2021315475A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022026285A1 (en) | 2022-02-03 |
| AU2021315475A1 (en) | 2023-03-02 |
| CN116490190A (zh) | 2023-07-25 |
| KR20230044252A (ko) | 2023-04-03 |
| EP4188379B1 (en) | 2026-02-25 |
| BR112023001325A2 (pt) | 2023-02-14 |
| EP4188379A4 (en) | 2024-08-28 |
| US20240018145A1 (en) | 2024-01-18 |
| EP4188379A1 (en) | 2023-06-07 |
| CA3187516A1 (en) | 2022-02-03 |
| JP2023535771A (ja) | 2023-08-21 |
| AU2021315475A8 (en) | 2023-04-06 |
| JP7695339B2 (ja) | 2025-06-18 |
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