MX2022004303A - Novedosa variante de acetohidroxiacido sintasa y microorganismo que incluye la misma. - Google Patents

Novedosa variante de acetohidroxiacido sintasa y microorganismo que incluye la misma.

Info

Publication number
MX2022004303A
MX2022004303A MX2022004303A MX2022004303A MX2022004303A MX 2022004303 A MX2022004303 A MX 2022004303A MX 2022004303 A MX2022004303 A MX 2022004303A MX 2022004303 A MX2022004303 A MX 2022004303A MX 2022004303 A MX2022004303 A MX 2022004303A
Authority
MX
Mexico
Prior art keywords
same
microgranisms
novel
acetohydroxyacid synthase
synthase variant
Prior art date
Application number
MX2022004303A
Other languages
English (en)
Inventor
Kwang Woo Lee
Imsang Lee
Tae Yeon Kim
Kyungrim Kim
Heeyeong Kim
Kwang Soo Shin
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of MX2022004303A publication Critical patent/MX2022004303A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01—Transketolases and transaldolases (2.2.1)
    • C12Y202/01006—Acetolactate synthase (2.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente divulgación se refiere a una variante de acetohidroxiácido sintasa, a un polinucleótido que codifica la variante, a un microorganismo que incluye la variante, y a un procedimiento de producción de L-isoleucina mediante el uso del microorganismo.
MX2022004303A 2019-11-22 2020-06-10 Novedosa variante de acetohidroxiacido sintasa y microorganismo que incluye la misma. MX2022004303A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020190151672A KR102147381B1 (ko) 2019-11-22 2019-11-22 아세토하이드록시산 신타제 신규 변이체 및 이를 포함하는 미생물
PCT/KR2020/007529 WO2021101000A1 (ko) 2019-11-22 2020-06-10 아세토하이드록시산 신타제 신규 변이체 및 이를 포함하는 미생물

Publications (1)

Publication Number Publication Date
MX2022004303A true MX2022004303A (es) 2022-05-10

Family

ID=72235100

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022004303A MX2022004303A (es) 2019-11-22 2020-06-10 Novedosa variante de acetohidroxiacido sintasa y microorganismo que incluye la misma.

Country Status (10)

Country Link
US (1) US20230203106A1 (es)
EP (1) EP4023751A4 (es)
JP (1) JP7470187B2 (es)
KR (1) KR102147381B1 (es)
CN (1) CN115052976B (es)
AR (1) AR120417A1 (es)
AU (1) AU2020388499A1 (es)
BR (1) BR112022007880A2 (es)
MX (1) MX2022004303A (es)
WO (1) WO2021101000A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240105550A (ko) * 2022-12-28 2024-07-08 씨제이제일제당 (주) 신규한 아세토락테이트 합성효소 활성을 갖는 변이체 폴리펩티드 및 이를 이용한 l-글루탐산 생산 방법

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BR9604993B1 (pt) * 1995-04-20 2009-05-05 dna mutante codificando uma proteìna ahas mutante de sìntese de ácido acetohidróxi e proteìnas ahas mutantes.
KR100264741B1 (ko) 1998-06-19 2000-10-02 손경식 글루탐산을 생산하는 미생물 및 이를 이용한 글루탐산의 제조방법
MXPA02001174A (es) 1999-08-02 2002-07-30 Archer Daniels Midland Co Ingenieria metabolica de la produccion de aminoacidos.
EP1491634A1 (en) * 2003-06-26 2004-12-29 Degussa AG Feedback resistant acetohydroxy acid synthetase mutants
KR100620092B1 (ko) 2004-12-16 2006-09-08 씨제이 주식회사 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법
HUE029181T2 (en) * 2005-07-01 2017-02-28 Basf Se Polynucleotides encoding herbicide-resistant sunflower plants, herbicide-resistant acetohydroxyacetic acid synthase high-subunit protein, and their application methods
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KR101632642B1 (ko) 2015-01-29 2016-06-22 씨제이제일제당 주식회사 신규한 프로모터 및 그의 용도
KR101747542B1 (ko) * 2015-10-23 2017-06-15 씨제이제일제당 (주) L-이소루신 생산능을 가지는 코리네박테리움 속 미생물 및 이를 이용하여 l-이소루신을 생산하는 방법
MY186296A (en) 2016-08-31 2021-07-06 Cj Cheiljedang Corp Novel promoter and use thereof
KR101996129B1 (ko) * 2017-07-11 2019-07-04 씨제이제일제당 (주) 아세토하이드록시산 신타아제 변이체, 이를 포함하는 미생물 또는 이를 이용하는 l-분지쇄 아미노산 생산 방법
CN109554324A (zh) * 2018-12-14 2019-04-02 江南大学 一株产l-异亮氨酸的黄色短杆菌重组菌及其构建方法
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Also Published As

Publication number Publication date
US20230203106A1 (en) 2023-06-29
JP2023503218A (ja) 2023-01-27
JP7470187B2 (ja) 2024-04-17
WO2021101000A1 (ko) 2021-05-27
CN115052976B (zh) 2023-12-19
KR102147381B1 (ko) 2020-08-24
CN115052976A (zh) 2022-09-13
EP4023751A1 (en) 2022-07-06
AR120417A1 (es) 2022-02-09
AU2020388499A1 (en) 2022-04-28
BR112022007880A2 (pt) 2022-07-12
EP4023751A4 (en) 2022-11-09

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