MX2021005877A - Compuesto heterociclico. - Google Patents

Compuesto heterociclico.

Info

Publication number
MX2021005877A
MX2021005877A MX2021005877A MX2021005877A MX2021005877A MX 2021005877 A MX2021005877 A MX 2021005877A MX 2021005877 A MX2021005877 A MX 2021005877A MX 2021005877 A MX2021005877 A MX 2021005877A MX 2021005877 A MX2021005877 A MX 2021005877A
Authority
MX
Mexico
Prior art keywords
heterocyclic compound
compound
cocrystal
solvate
prophylactic
Prior art date
Application number
MX2021005877A
Other languages
English (en)
Spanish (es)
Inventor
Shinichi Imamura
Hidekazu Tokuhara
Yoshiteru Ito
Takaharu Hirayama
Hiroshi Banno
Toshio Tanaka
Yasuyoshi Arikawa
Noriyuki Nii
Youichi Kawakita
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of MX2021005877A publication Critical patent/MX2021005877A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
MX2021005877A 2018-11-28 2019-11-27 Compuesto heterociclico. MX2021005877A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018222530 2018-11-28
PCT/JP2019/046261 WO2020111087A1 (ja) 2018-11-28 2019-11-27 複素環化合物

Publications (1)

Publication Number Publication Date
MX2021005877A true MX2021005877A (es) 2021-07-16

Family

ID=70853784

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2021005877A MX2021005877A (es) 2018-11-28 2019-11-27 Compuesto heterociclico.
MX2024003064A MX2024003064A (es) 2018-11-28 2021-05-19 Compuesto heterociclico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2024003064A MX2024003064A (es) 2018-11-28 2021-05-19 Compuesto heterociclico.

Country Status (16)

Country Link
US (4) US12152027B2 (enExample)
EP (1) EP3888652A4 (enExample)
JP (2) JP6972384B2 (enExample)
KR (2) KR102359143B1 (enExample)
CN (2) CN113038948B (enExample)
AU (1) AU2019390863B2 (enExample)
BR (1) BR112021009994A2 (enExample)
CA (1) CA3120774A1 (enExample)
IL (2) IL303962B1 (enExample)
MX (2) MX2021005877A (enExample)
MY (1) MY209902A (enExample)
PH (1) PH12021551251A1 (enExample)
SG (1) SG11202105652XA (enExample)
TW (3) TWI848400B (enExample)
WO (1) WO2020111087A1 (enExample)
ZA (1) ZA202104402B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102359143B1 (ko) * 2018-11-28 2022-02-08 다케다 야쿠힌 고교 가부시키가이샤 헤테로시클릭 화합물
US20230192685A1 (en) * 2020-05-27 2023-06-22 Takeda Pharmaceutical Company Limited Method for producing heterocyclic compound
CA3198715A1 (en) * 2020-10-16 2022-04-21 Rheos Medicines, Inc. Malt1 modulators and uses thereof
GB202018412D0 (en) 2020-11-23 2021-01-06 Exscientia Ltd Malt-1 modulators ii
US12252488B2 (en) * 2021-02-12 2025-03-18 Nimbus Saturn, Inc. HPK1 antagonists and uses thereof
AU2022425324A1 (en) 2021-12-30 2024-05-30 Jiangsu Hansoh Pharmaceutical Group Co., Ltd. Tricyclic derivative inhibitor, preparation method therefor, and application thereof
JPWO2023149450A1 (enExample) * 2022-02-02 2023-08-10
US20250188081A1 (en) * 2023-12-08 2025-06-12 Shaman Pharma, LLC Method for Production of Spiro-Oxindole and Indoxyl Derivatives of Mitragynine

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2288521A1 (fr) 1974-10-25 1976-05-21 Merck Patent Gmbh Nouvelles penicillines et procede pour leur preparation
EP0842933B1 (en) * 1995-05-31 2004-08-04 Sumitomo Pharmaceuticals Company, Limited Novel naphthyridine derivatives
GB9720052D0 (en) 1997-09-19 1997-11-19 Smithkline Beecham Plc Novel compounds
GB201321734D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic Agents
KR20170007311A (ko) * 2014-05-28 2017-01-18 노파르티스 아게 신규 피라졸로 피리미딘 유도체 및 malt1 억제제로서의 그의 용도
MX2018005390A (es) * 2015-11-13 2018-08-16 Novartis Ag Nuevos derivados de pirazolo pirimidina.
KR20190033607A (ko) 2016-07-29 2019-03-29 루핀 리미티드 Malt1 저해제로서의 치환 티아졸로-피리딘 화합물
WO2018085247A1 (en) * 2016-11-01 2018-05-11 Cornell University Compounds for malt1 degradation
WO2018165385A1 (en) * 2017-03-08 2018-09-13 Cornell University Inhibitors of malt1 and uses thereof
US20200111087A1 (en) * 2018-10-08 2020-04-09 Jinlei Zhou Method for encrypting digital contract document between contractors
KR102359143B1 (ko) * 2018-11-28 2022-02-08 다케다 야쿠힌 고교 가부시키가이샤 헤테로시클릭 화합물

Also Published As

Publication number Publication date
TWI848400B (zh) 2024-07-11
TW202438498A (zh) 2024-10-01
EP3888652A1 (en) 2021-10-06
KR20220019848A (ko) 2022-02-17
SG11202105652XA (en) 2021-06-29
EP3888652A4 (en) 2022-10-19
BR112021009994A2 (pt) 2021-08-17
US20220089595A1 (en) 2022-03-24
AU2019390863A1 (en) 2021-06-24
MX2024003064A (es) 2024-03-27
TWI784213B (zh) 2022-11-21
CN118420620A (zh) 2024-08-02
CN113038948A (zh) 2021-06-25
CN113038948B (zh) 2024-07-12
JP2022017461A (ja) 2022-01-25
US11230545B2 (en) 2022-01-25
JP7434249B2 (ja) 2024-02-20
IL303962B1 (en) 2026-01-01
WO2020111087A9 (ja) 2021-01-21
US11897879B2 (en) 2024-02-13
AU2019390863A2 (en) 2021-07-01
US12152027B2 (en) 2024-11-26
KR102359143B1 (ko) 2022-02-08
PH12021551251A1 (en) 2021-12-06
KR102646470B1 (ko) 2024-03-11
US20210332045A1 (en) 2021-10-28
TW202306956A (zh) 2023-02-16
ZA202104402B (en) 2023-01-25
MY209902A (en) 2025-08-09
IL303962A (en) 2023-08-01
US20250034141A1 (en) 2025-01-30
JPWO2020111087A1 (ja) 2021-09-27
NZ777412A (en) 2024-05-31
IL283368B1 (en) 2024-09-01
TW202039484A (zh) 2020-11-01
JP6972384B2 (ja) 2021-11-24
US20220048916A1 (en) 2022-02-17
CA3120774A1 (en) 2020-06-04
IL283368B2 (en) 2025-01-01
KR20210092301A (ko) 2021-07-23
IL283368A (en) 2021-07-29
AU2019390863B2 (en) 2025-02-20
WO2020111087A1 (ja) 2020-06-04

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