MX2021005877A - Compuesto heterociclico. - Google Patents

Compuesto heterociclico.

Info

Publication number
MX2021005877A
MX2021005877A MX2021005877A MX2021005877A MX2021005877A MX 2021005877 A MX2021005877 A MX 2021005877A MX 2021005877 A MX2021005877 A MX 2021005877A MX 2021005877 A MX2021005877 A MX 2021005877A MX 2021005877 A MX2021005877 A MX 2021005877A
Authority
MX
Mexico
Prior art keywords
heterocyclic compound
compound
cocrystal
solvate
prophylactic
Prior art date
Application number
MX2021005877A
Other languages
English (en)
Spanish (es)
Inventor
Shinichi Imamura
Hidekazu Tokuhara
Yoshiteru Ito
Takaharu Hirayama
Hiroshi Banno
Toshio Tanaka
Yasuyoshi Arikawa
Noriyuki Nii
Youichi Kawakita
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of MX2021005877A publication Critical patent/MX2021005877A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
MX2021005877A 2018-11-28 2019-11-27 Compuesto heterociclico. MX2021005877A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018222530 2018-11-28
PCT/JP2019/046261 WO2020111087A1 (ja) 2018-11-28 2019-11-27 複素環化合物

Publications (1)

Publication Number Publication Date
MX2021005877A true MX2021005877A (es) 2021-07-16

Family

ID=70853784

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2021005877A MX2021005877A (es) 2018-11-28 2019-11-27 Compuesto heterociclico.
MX2024003064A MX2024003064A (es) 2018-11-28 2021-05-19 Compuesto heterociclico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2024003064A MX2024003064A (es) 2018-11-28 2021-05-19 Compuesto heterociclico.

Country Status (16)

Country Link
US (4) US12152027B2 (enExample)
EP (1) EP3888652A4 (enExample)
JP (2) JP6972384B2 (enExample)
KR (2) KR102646470B1 (enExample)
CN (2) CN113038948B (enExample)
AU (1) AU2019390863B2 (enExample)
BR (1) BR112021009994A2 (enExample)
CA (1) CA3120774A1 (enExample)
IL (2) IL283368B2 (enExample)
MX (2) MX2021005877A (enExample)
MY (1) MY209902A (enExample)
PH (1) PH12021551251A1 (enExample)
SG (1) SG11202105652XA (enExample)
TW (2) TWI848400B (enExample)
WO (1) WO2020111087A1 (enExample)
ZA (1) ZA202104402B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021009994A2 (pt) * 2018-11-28 2021-08-17 Takeda Pharmaceutical Company Limited composto, e, medicamento
EP4163280A4 (en) * 2020-05-27 2024-06-05 Takeda Pharmaceutical Company Limited METHOD FOR PRODUCING A HETEROCYCLIC COMPOUND
WO2022081967A1 (en) * 2020-10-16 2022-04-21 Rheos Medicines, Inc. Malt1 modulators and uses thereof
GB202018412D0 (en) 2020-11-23 2021-01-06 Exscientia Ltd Malt-1 modulators ii
WO2022174253A1 (en) * 2021-02-12 2022-08-18 Nimbus Saturn, Inc. Hpk1 antagonists and uses thereof
JP2025501056A (ja) 2021-12-30 2025-01-17 シャンハイ ハンソー バイオメディカル カンパニー リミテッド 三環系誘導体阻害剤、その製造方法と応用
KR20240144146A (ko) 2022-02-02 2024-10-02 오노 야꾸힝 고교 가부시키가이샤 Malt1 저해약을 유효 성분으로서 포함하는 암 치료제
US20250188081A1 (en) * 2023-12-08 2025-06-12 Shaman Pharma, LLC Method for Production of Spiro-Oxindole and Indoxyl Derivatives of Mitragynine

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2288521A1 (fr) 1974-10-25 1976-05-21 Merck Patent Gmbh Nouvelles penicillines et procede pour leur preparation
CA2222687A1 (en) * 1995-05-31 1996-12-05 Masami Muraoka Novel naphthyridine derivatives
GB9720052D0 (en) * 1997-09-19 1997-11-19 Smithkline Beecham Plc Novel compounds
GB201321734D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic Agents
JP6545197B2 (ja) * 2014-05-28 2019-07-17 ノバルティス アーゲー 新規なピラゾロピリミジン誘導体およびmalt1阻害剤としてのその使用
EP3374361A1 (en) * 2015-11-13 2018-09-19 Novartis AG Novel pyrazolo pyrimidine derivatives
WO2018020474A1 (en) * 2016-07-29 2018-02-01 Lupin Limited Substituted thiazolo-pyridine compounds as malt1 inhibitors
US10689366B2 (en) * 2016-11-01 2020-06-23 Cornell University Compounds for MALT1 degredation
EP3592731A4 (en) * 2017-03-08 2020-10-07 Cornell University MALT1 INHIBITORS AND THEIR USES
US20200111087A1 (en) * 2018-10-08 2020-04-09 Jinlei Zhou Method for encrypting digital contract document between contractors
BR112021009994A2 (pt) * 2018-11-28 2021-08-17 Takeda Pharmaceutical Company Limited composto, e, medicamento

Also Published As

Publication number Publication date
IL283368A (en) 2021-07-29
KR20210092301A (ko) 2021-07-23
SG11202105652XA (en) 2021-06-29
NZ777412A (en) 2024-05-31
TWI848400B (zh) 2024-07-11
CN118420620A (zh) 2024-08-02
US20250034141A1 (en) 2025-01-30
CN113038948B (zh) 2024-07-12
TWI784213B (zh) 2022-11-21
TW202438498A (zh) 2024-10-01
JP6972384B2 (ja) 2021-11-24
MX2024003064A (es) 2024-03-27
US11897879B2 (en) 2024-02-13
JP2022017461A (ja) 2022-01-25
US11230545B2 (en) 2022-01-25
WO2020111087A9 (ja) 2021-01-21
TW202306956A (zh) 2023-02-16
MY209902A (en) 2025-08-09
BR112021009994A2 (pt) 2021-08-17
US20210332045A1 (en) 2021-10-28
PH12021551251A1 (en) 2021-12-06
AU2019390863B2 (en) 2025-02-20
AU2019390863A1 (en) 2021-06-24
US20220089595A1 (en) 2022-03-24
TW202039484A (zh) 2020-11-01
JP7434249B2 (ja) 2024-02-20
IL303962B2 (en) 2026-05-01
ZA202104402B (en) 2023-01-25
IL303962B1 (en) 2026-01-01
IL303962A (en) 2023-08-01
EP3888652A4 (en) 2022-10-19
EP3888652A1 (en) 2021-10-06
JPWO2020111087A1 (ja) 2021-09-27
KR102646470B1 (ko) 2024-03-11
CN113038948A (zh) 2021-06-25
CA3120774A1 (en) 2020-06-04
IL283368B2 (en) 2025-01-01
US12152027B2 (en) 2024-11-26
KR20220019848A (ko) 2022-02-17
US20220048916A1 (en) 2022-02-17
KR102359143B1 (ko) 2022-02-08
AU2019390863A2 (en) 2021-07-01
WO2020111087A1 (ja) 2020-06-04
IL283368B1 (en) 2024-09-01

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