SG11202105652XA - Heterocyclic compound - Google Patents

Heterocyclic compound

Info

Publication number
SG11202105652XA
SG11202105652XA SG11202105652XA SG11202105652XA SG11202105652XA SG 11202105652X A SG11202105652X A SG 11202105652XA SG 11202105652X A SG11202105652X A SG 11202105652XA SG 11202105652X A SG11202105652X A SG 11202105652XA SG 11202105652X A SG11202105652X A SG 11202105652XA
Authority
SG
Singapore
Prior art keywords
heterocyclic compound
heterocyclic
compound
Prior art date
Application number
SG11202105652XA
Inventor
Takaharu Hirayama
Yoshiteru Ito
Hiroshi Banno
Hidekazu Tokuhara
Toshio Tanaka
Yasuyoshi Arikawa
Noriyuki Nii
Youichi Kawakita
Shinichi Imamura
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of SG11202105652XA publication Critical patent/SG11202105652XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
SG11202105652XA 2018-11-28 2019-11-27 Heterocyclic compound SG11202105652XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018222530 2018-11-28
PCT/JP2019/046261 WO2020111087A1 (en) 2018-11-28 2019-11-27 Heterocyclic compound

Publications (1)

Publication Number Publication Date
SG11202105652XA true SG11202105652XA (en) 2021-06-29

Family

ID=70853784

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202105652XA SG11202105652XA (en) 2018-11-28 2019-11-27 Heterocyclic compound

Country Status (15)

Country Link
US (3) US20220048916A1 (en)
EP (1) EP3888652A4 (en)
JP (2) JP6972384B2 (en)
KR (2) KR102646470B1 (en)
CN (1) CN113038948A (en)
AU (1) AU2019390863A1 (en)
BR (1) BR112021009994A2 (en)
CA (1) CA3120774A1 (en)
IL (2) IL303962A (en)
MX (1) MX2021005877A (en)
PH (1) PH12021551251A1 (en)
SG (1) SG11202105652XA (en)
TW (2) TWI784213B (en)
WO (1) WO2020111087A1 (en)
ZA (1) ZA202104402B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021005877A (en) * 2018-11-28 2021-07-16 Takeda Pharmaceuticals Co Heterocyclic compound.
JPWO2021241611A1 (en) 2020-05-27 2021-12-02
GB202018412D0 (en) 2020-11-23 2021-01-06 Exscientia Ltd Malt-1 modulators ii
TW202342032A (en) * 2022-02-02 2023-11-01 日商小野藥品工業股份有限公司 Cancer therapeutic agent containing malt1 inhibitor as an active ingredient

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2288521A1 (en) * 1974-10-25 1976-05-21 Merck Patent Gmbh NEW PENICILLINS AND PROCESS FOR THEIR PREPARATION
CN1065243C (en) * 1995-05-31 2001-05-02 住友制药株式会社 Naphthyridine derivs.
GB9720052D0 (en) * 1997-09-19 1997-11-19 Smithkline Beecham Plc Novel compounds
GB201321734D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic Agents
ES2738695T3 (en) 2014-05-28 2020-01-24 Novartis Ag New Pirazolo Pyrimidine Derivatives and their use as MALT1 inhibitors
JP2018533610A (en) 2015-11-13 2018-11-15 ノバルティス アーゲー Novel pyrazolo pyrimidine derivatives
MX2019001132A (en) * 2016-07-29 2019-12-16 Lupin Ltd Substituted thiazolo-pyridine compounds as malt1 inhibitors.
EP3535254A4 (en) * 2016-11-01 2020-06-24 Cornell University Cornell Center For Technology, Enterprise & Commercialization ("CCTEC") Compounds for malt1 degradation
EP3592731A4 (en) * 2017-03-08 2020-10-07 Cornell University Inhibitors of malt1 and uses thereof
US20200111087A1 (en) * 2018-10-08 2020-04-09 Jinlei Zhou Method for encrypting digital contract document between contractors
MX2021005877A (en) * 2018-11-28 2021-07-16 Takeda Pharmaceuticals Co Heterocyclic compound.

Also Published As

Publication number Publication date
US20220089595A1 (en) 2022-03-24
US20220048916A1 (en) 2022-02-17
WO2020111087A9 (en) 2021-01-21
AU2019390863A2 (en) 2021-07-01
AU2019390863A1 (en) 2021-06-24
US11897879B2 (en) 2024-02-13
IL283368A (en) 2021-07-29
TWI784213B (en) 2022-11-21
IL303962A (en) 2023-08-01
EP3888652A4 (en) 2022-10-19
KR20210092301A (en) 2021-07-23
KR102359143B1 (en) 2022-02-08
KR102646470B1 (en) 2024-03-11
MX2021005877A (en) 2021-07-16
BR112021009994A2 (en) 2021-08-17
PH12021551251A1 (en) 2021-12-06
CN113038948A (en) 2021-06-25
CA3120774A1 (en) 2020-06-04
TW202039484A (en) 2020-11-01
JPWO2020111087A1 (en) 2021-09-27
EP3888652A1 (en) 2021-10-06
KR20220019848A (en) 2022-02-17
US20210332045A1 (en) 2021-10-28
JP7434249B2 (en) 2024-02-20
WO2020111087A1 (en) 2020-06-04
US11230545B2 (en) 2022-01-25
TW202306956A (en) 2023-02-16
JP2022017461A (en) 2022-01-25
JP6972384B2 (en) 2021-11-24
ZA202104402B (en) 2023-01-25

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