MX2021003745A - Composiciones y métodos relacionados con células t gamma delta modificadas y no modificadas para el tratamiento de tumores hematológicos. - Google Patents

Composiciones y métodos relacionados con células t gamma delta modificadas y no modificadas para el tratamiento de tumores hematológicos.

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Publication number
MX2021003745A
MX2021003745A MX2021003745A MX2021003745A MX2021003745A MX 2021003745 A MX2021003745 A MX 2021003745A MX 2021003745 A MX2021003745 A MX 2021003745A MX 2021003745 A MX2021003745 A MX 2021003745A MX 2021003745 A MX2021003745 A MX 2021003745A
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Mexico
Prior art keywords
engineered
domain
cells
hematological tumors
compositions
Prior art date
Application number
MX2021003745A
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English (en)
Spanish (es)
Inventor
Aya Jakobovits
Daulet Kadyl Satpayev
Yifeng Frank Jing
Zili An
Jason Michael Romero
Marissa Ann Herrman
Original Assignee
Adicet Bio Inc
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Publication of MX2021003745A publication Critical patent/MX2021003745A/es

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
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MX2021003745A 2018-10-01 2019-10-01 Composiciones y métodos relacionados con células t gamma delta modificadas y no modificadas para el tratamiento de tumores hematológicos. MX2021003745A (es)

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US201862739822P 2018-10-01 2018-10-01
PCT/US2019/054132 WO2020072536A1 (en) 2018-10-01 2019-10-01 COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON- ENGINEERED γδ-Τ CELLS FOR TREATMENT OF HEMATOLOGICAL TUMORS

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CN108395482B (zh) 2017-02-08 2021-02-05 西比曼生物科技（香港）有限公司 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
EP4004049A1 (en) * 2019-07-24 2022-06-01 Regeneron Pharmaceuticals, Inc. Chimeric antigen receptors with mage-a4 specificity and uses thereof
CN113402612A (zh) 2020-03-17 2021-09-17 西比曼生物科技（香港）有限公司 靶向cd19和cd20的联合嵌合抗原受体及其应用
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