EA202190926A1 - Композиции и способы в отношении сконструированных и несконструированных t-клеток для лечения гематологических опухолей - Google Patents

Композиции и способы в отношении сконструированных и несконструированных t-клеток для лечения гематологических опухолей

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Publication number
EA202190926A1
EA202190926A1 EA202190926A EA202190926A EA202190926A1 EA 202190926 A1 EA202190926 A1 EA 202190926A1 EA 202190926 A EA202190926 A EA 202190926A EA 202190926 A EA202190926 A EA 202190926A EA 202190926 A1 EA202190926 A1 EA 202190926A1
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EA
Eurasian Patent Office
Prior art keywords
domain
cells
methods
compositions
unconstructed
Prior art date
Application number
EA202190926A
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English (en)
Russian (ru)
Inventor
Даулет Кадил Сатпаев
Марисса Энн Херрман
Джейсон Майкл Ромеро
Ифэн Фрэнк Цзин
Цили Ан
Айя Якобовиц
Original Assignee
Эдисет Био, Инк.
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Application filed by Эдисет Био, Инк. filed Critical Эдисет Био, Инк.
Publication of EA202190926A1 publication Critical patent/EA202190926A1/ru

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    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • C12N15/62DNA sequences coding for fusion proteins
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EA202190926A 2018-10-01 2019-10-01 Композиции и способы в отношении сконструированных и несконструированных t-клеток для лечения гематологических опухолей EA202190926A1 (ru)

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US201862739822P 2018-10-01 2018-10-01
PCT/US2019/054132 WO2020072536A1 (en) 2018-10-01 2019-10-01 COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON- ENGINEERED γδ-Τ CELLS FOR TREATMENT OF HEMATOLOGICAL TUMORS

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EA202190926A1 true EA202190926A1 (ru) 2021-06-25

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US (1) US20210388100A1 (enExample)
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KR (1) KR20210070330A (enExample)
CN (1) CN113056283A (enExample)
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CN108395482B (zh) 2017-02-08 2021-02-05 西比曼生物科技(香港)有限公司 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
EP4004049A1 (en) * 2019-07-24 2022-06-01 Regeneron Pharmaceuticals, Inc. Chimeric antigen receptors with mage-a4 specificity and uses thereof
CN113402612A (zh) 2020-03-17 2021-09-17 西比曼生物科技(香港)有限公司 靶向cd19和cd20的联合嵌合抗原受体及其应用
CN113667640B (zh) * 2021-08-27 2022-09-02 广州百暨基因科技有限公司 CAR-γδT细胞的制备方法
WO2023102264A1 (en) * 2021-12-05 2023-06-08 Adicet Therapeutics, Inc. Treatment of b cell malignancies
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