MX2021000308A - Composiciones de fusosoma y usos de estas. - Google Patents
Composiciones de fusosoma y usos de estas.Info
- Publication number
- MX2021000308A MX2021000308A MX2021000308A MX2021000308A MX2021000308A MX 2021000308 A MX2021000308 A MX 2021000308A MX 2021000308 A MX2021000308 A MX 2021000308A MX 2021000308 A MX2021000308 A MX 2021000308A MX 2021000308 A MX2021000308 A MX 2021000308A
- Authority
- MX
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- Prior art keywords
- fusosome
- regulatory element
- target cell
- compositions
- specific regulatory
- Prior art date
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10041—Use of virus, viral particle or viral elements as a vector
- C12N2740/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
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- C12N2760/18011—Paramyxoviridae
- C12N2760/18211—Henipavirus, e.g. hendra virus
- C12N2760/18222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18822—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
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- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
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- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La presente descripción proporciona, al menos en parte, métodos y composiciones para la administración in vivo de fusosoma. En algunas modalidades, el fusosoma comprende una combinación de elementos que promueven la especificidad por las células diana, por ejemplo, uno o más de un fusógeno, un elemento regulador positivo específico de la célula diana y un elemento regulador específico de la célula no diana. En algunas modalidades, el fusosoma comprende una o más modificaciones que disminuyen una respuesta inmune contra el fusosoma.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862695650P | 2018-07-09 | 2018-07-09 | |
US201862695537P | 2018-07-09 | 2018-07-09 | |
US201862767261P | 2018-11-14 | 2018-11-14 | |
US201862767241P | 2018-11-14 | 2018-11-14 | |
US201962848305P | 2019-05-15 | 2019-05-15 | |
US201962848284P | 2019-05-15 | 2019-05-15 | |
PCT/US2019/040978 WO2020014209A1 (en) | 2018-07-09 | 2019-07-09 | Fusosome compositions and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021000308A true MX2021000308A (es) | 2021-06-08 |
Family
ID=67659932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021000308A MX2021000308A (es) | 2018-07-09 | 2019-07-09 | Composiciones de fusosoma y usos de estas. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP3820509A1 (es) |
JP (1) | JP2021530985A (es) |
KR (1) | KR20210043574A (es) |
CN (1) | CN112955174A (es) |
AU (1) | AU2019301053A1 (es) |
BR (1) | BR112021000145A2 (es) |
CA (1) | CA3105953A1 (es) |
IL (1) | IL279897A (es) |
MX (1) | MX2021000308A (es) |
SG (1) | SG11202100071YA (es) |
WO (1) | WO2020014209A1 (es) |
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-
2019
- 2019-07-09 BR BR112021000145-0A patent/BR112021000145A2/pt unknown
- 2019-07-09 CN CN201980058212.6A patent/CN112955174A/zh active Pending
- 2019-07-09 AU AU2019301053A patent/AU2019301053A1/en active Pending
- 2019-07-09 JP JP2021500638A patent/JP2021530985A/ja active Pending
- 2019-07-09 WO PCT/US2019/040978 patent/WO2020014209A1/en active Application Filing
- 2019-07-09 KR KR1020217003524A patent/KR20210043574A/ko unknown
- 2019-07-09 SG SG11202100071YA patent/SG11202100071YA/en unknown
- 2019-07-09 MX MX2021000308A patent/MX2021000308A/es unknown
- 2019-07-09 CA CA3105953A patent/CA3105953A1/en active Pending
- 2019-07-09 EP EP19753491.0A patent/EP3820509A1/en active Pending
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2020
- 2020-12-31 IL IL279897A patent/IL279897A/en unknown
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AU2019301053A1 (en) | 2021-01-28 |
EP3820509A1 (en) | 2021-05-19 |
CN112955174A (zh) | 2021-06-11 |
CA3105953A1 (en) | 2020-01-16 |
JP2021530985A (ja) | 2021-11-18 |
IL279897A (en) | 2021-03-01 |
BR112021000145A2 (pt) | 2021-04-06 |
WO2020014209A1 (en) | 2020-01-16 |
KR20210043574A (ko) | 2021-04-21 |
SG11202100071YA (en) | 2021-02-25 |
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