MX2020010320A - Composiciones de erenumab y usos de las mismas. - Google Patents

Composiciones de erenumab y usos de las mismas.

Info

Publication number
MX2020010320A
MX2020010320A MX2020010320A MX2020010320A MX2020010320A MX 2020010320 A MX2020010320 A MX 2020010320A MX 2020010320 A MX2020010320 A MX 2020010320A MX 2020010320 A MX2020010320 A MX 2020010320A MX 2020010320 A MX2020010320 A MX 2020010320A
Authority
MX
Mexico
Prior art keywords
erenumab
compositions
variants
erenumab compositions
characterization
Prior art date
Application number
MX2020010320A
Other languages
English (en)
Spanish (es)
Inventor
Kenneth Lawson
Noel Rieder
Suminda Hapuarachchi
Jose Gregorio Ramirez
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2020010320A publication Critical patent/MX2020010320A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
MX2020010320A 2018-04-02 2019-04-01 Composiciones de erenumab y usos de las mismas. MX2020010320A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862651651P 2018-04-02 2018-04-02
PCT/US2019/025223 WO2019195185A1 (en) 2018-04-02 2019-04-01 Erenumab compositions and uses thereof

Publications (1)

Publication Number Publication Date
MX2020010320A true MX2020010320A (es) 2021-01-08

Family

ID=66248665

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020010320A MX2020010320A (es) 2018-04-02 2019-04-01 Composiciones de erenumab y usos de las mismas.

Country Status (19)

Country Link
US (2) US11407838B2 (enExample)
EP (1) EP3774881A1 (enExample)
JP (3) JP7840636B2 (enExample)
KR (1) KR20200139720A (enExample)
CN (1) CN111954678A (enExample)
AR (1) AR114722A1 (enExample)
AU (1) AU2019246983B2 (enExample)
BR (1) BR112020019882A2 (enExample)
CA (1) CA3095899A1 (enExample)
CL (2) CL2020002519A1 (enExample)
EA (1) EA202092335A1 (enExample)
IL (1) IL277663A (enExample)
MA (1) MA52202A (enExample)
MX (1) MX2020010320A (enExample)
PH (1) PH12020551618A1 (enExample)
SA (1) SA520420261B1 (enExample)
SG (1) SG11202009629YA (enExample)
TW (1) TWI847980B (enExample)
WO (1) WO2019195185A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3382B1 (ar) * 2008-12-23 2019-03-13 Amgen Inc أجسام مضادة ترتبط مع مستقبل cgrp بشري
WO2022232376A1 (en) * 2021-04-29 2022-11-03 Amgen Inc. Methods for reducing low molecular weight species of recombinantly-produced proteins
EP4455163A4 (en) * 2021-12-22 2025-12-24 Chugai Pharmaceutical Co Ltd REDUCED BIOLOGICALLY ACTIVE ANTIBODY VARIANT
CN115819589A (zh) * 2022-10-19 2023-03-21 武汉人福创新药物研发中心有限公司 一种培养基及生产抗cgrpr抗体的方法

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Also Published As

Publication number Publication date
EP3774881A1 (en) 2021-02-17
US11407838B2 (en) 2022-08-09
BR112020019882A2 (pt) 2021-01-05
TW202003572A (zh) 2020-01-16
TWI847980B (zh) 2024-07-11
WO2019195185A1 (en) 2019-10-10
AU2019246983B2 (en) 2025-12-18
PH12020551618A1 (en) 2021-08-16
US20220348673A1 (en) 2022-11-03
AR114722A1 (es) 2020-10-07
US20190300617A1 (en) 2019-10-03
SA520420261B1 (ar) 2024-05-23
MA52202A (fr) 2021-02-17
JP2023103323A (ja) 2023-07-26
JP2026034591A (ja) 2026-02-27
CA3095899A1 (en) 2019-10-10
KR20200139720A (ko) 2020-12-14
AU2019246983A1 (en) 2020-10-29
CL2023000491A1 (es) 2023-10-13
JP2021519790A (ja) 2021-08-12
SG11202009629YA (en) 2020-10-29
JP7840636B2 (ja) 2026-04-06
EA202092335A1 (ru) 2021-01-22
CN111954678A (zh) 2020-11-17
IL277663A (en) 2020-11-30
CL2020002519A1 (es) 2021-04-05

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