MX2020006655A - Biorreactor y metodos relacionados. - Google Patents

Biorreactor y metodos relacionados.

Info

Publication number
MX2020006655A
MX2020006655A MX2020006655A MX2020006655A MX2020006655A MX 2020006655 A MX2020006655 A MX 2020006655A MX 2020006655 A MX2020006655 A MX 2020006655A MX 2020006655 A MX2020006655 A MX 2020006655A MX 2020006655 A MX2020006655 A MX 2020006655A
Authority
MX
Mexico
Prior art keywords
bioreactor
chamber
modular
related methods
impeller
Prior art date
Application number
MX2020006655A
Other languages
English (en)
Inventor
Bastien Mairesse
Josè Castillo
Sèbastien Jean- Pierre Michel RODRIGUEZ
Original Assignee
Univercells Tech S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univercells Tech S A filed Critical Univercells Tech S A
Publication of MX2020006655A publication Critical patent/MX2020006655A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C12M25/18—Fixed or packed bed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18—Flow directing inserts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18—Flow directing inserts
    • C12M27/20—Baffles; Ribs; Ribbons; Auger vanes

Abstract

Se describe un aparato para el cultivo de células que incluye un biorreactor; el biorreactor puede ser modular y puede incluir en una cámara un lecho fijo, tal como un lecho fijo no estructurado o estructurado (tal como un lecho espiral) para el cultivo de células, con una columna de regreso dispuesta centralmente dentro de la cámara; el biorreactor modular puede incluir una pluralidad de lechos fijos estructurados dispuestos en una configuración apilada; el biorreactor modular puede incluir una cubierta exterior que forma un espacio para acondicionar (por ejemplo, aislar, calentar, enfriar) por lo menos una cámara en donde se cultivan las células; el biorreactor puede incluir también un propulsor con paletas radialmente encorvadas, y puede suspender también el propulsor para que pueda moverse de lado a lado y alinearse con un sistema de mando externo; se describen también métodos relacionados.
MX2020006655A 2017-12-20 2018-12-20 Biorreactor y metodos relacionados. MX2020006655A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762608261P 2017-12-20 2017-12-20
US201862733375P 2018-09-19 2018-09-19
US201862758152P 2018-11-09 2018-11-09
PCT/EP2018/086394 WO2019122239A1 (en) 2017-12-20 2018-12-20 Bioreactor and related methods

Publications (1)

Publication Number Publication Date
MX2020006655A true MX2020006655A (es) 2021-01-08

Family

ID=65013665

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020006655A MX2020006655A (es) 2017-12-20 2018-12-20 Biorreactor y metodos relacionados.

Country Status (12)

Country Link
US (3) US20210130760A1 (es)
EP (1) EP3728549A1 (es)
JP (2) JP7433232B2 (es)
KR (1) KR20200118416A (es)
CN (1) CN111801410A (es)
AU (1) AU2018386438A1 (es)
BR (1) BR112020012574A2 (es)
CA (1) CA3086283A1 (es)
MX (1) MX2020006655A (es)
RU (1) RU2020123777A (es)
SG (1) SG11202005815UA (es)
WO (1) WO2019122239A1 (es)

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Also Published As

Publication number Publication date
KR20200118416A (ko) 2020-10-15
RU2020123777A (ru) 2022-01-21
WO2019122239A1 (en) 2019-06-27
SG11202005815UA (en) 2020-07-29
JP2021508445A (ja) 2021-03-11
US20230272324A1 (en) 2023-08-31
JP2024023339A (ja) 2024-02-21
CN111801410A (zh) 2020-10-20
CA3086283A1 (en) 2019-06-27
US20220396754A1 (en) 2022-12-15
BR112020012574A2 (pt) 2020-11-24
AU2018386438A1 (en) 2020-08-06
JP7433232B2 (ja) 2024-02-19
US20210130760A1 (en) 2021-05-06
EP3728549A1 (en) 2020-10-28
US11680237B2 (en) 2023-06-20

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