MX2020004901A - Un proceso novedoso homogeneo en un solo paso para la preparacion a gran escala de bencimidazoles sustituidos en la posicion 2. - Google Patents

Un proceso novedoso homogeneo en un solo paso para la preparacion a gran escala de bencimidazoles sustituidos en la posicion 2.

Info

Publication number
MX2020004901A
MX2020004901A MX2020004901A MX2020004901A MX2020004901A MX 2020004901 A MX2020004901 A MX 2020004901A MX 2020004901 A MX2020004901 A MX 2020004901A MX 2020004901 A MX2020004901 A MX 2020004901A MX 2020004901 A MX2020004901 A MX 2020004901A
Authority
MX
Mexico
Prior art keywords
novel
large scale
substituted benzimidazoles
scale manufacture
homogeneous process
Prior art date
Application number
MX2020004901A
Other languages
English (en)
Inventor
Pradeep Cheruku
SRIRAM Suresh R
James Joseph Michels
Original Assignee
Ecolab Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ecolab Usa Inc filed Critical Ecolab Usa Inc
Publication of MX2020004901A publication Critical patent/MX2020004901A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23F—NON-MECHANICAL REMOVAL OF METALLIC MATERIAL FROM SURFACE; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL; MULTI-STEP PROCESSES FOR SURFACE TREATMENT OF METALLIC MATERIAL INVOLVING AT LEAST ONE PROCESS PROVIDED FOR IN CLASS C23 AND AT LEAST ONE PROCESS COVERED BY SUBCLASS C21D OR C22F OR CLASS C25
    • C23F11/00—Inhibiting corrosion of metallic material by applying inhibitors to the surface in danger of corrosion or adding them to the corrosive agent
    • C23F11/08—Inhibiting corrosion of metallic material by applying inhibitors to the surface in danger of corrosion or adding them to the corrosive agent in other liquids
    • C23F11/10—Inhibiting corrosion of metallic material by applying inhibitors to the surface in danger of corrosion or adding them to the corrosive agent in other liquids using organic inhibitors
    • C23F11/14—Nitrogen-containing compounds
    • C23F11/149—Heterocyclic compounds containing nitrogen as hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Metallurgy (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

Se divulgan bencimidazoles 2-sustituidos y métodos para preparar los mismos. Las composiciones pueden incluir un compuesto o una sal de este, un ácido y un solvente aprótico polar. Las composiciones pueden usarse para inhibir la corrosión de una superficie de metal en contacto con un sistema acuoso, y proporcionar una protección mejorada contra la corrosión de metales en el sistema acuoso. Fórmula (I). (VER FORMULA).
MX2020004901A 2017-11-13 2018-11-09 Un proceso novedoso homogeneo en un solo paso para la preparacion a gran escala de bencimidazoles sustituidos en la posicion 2. MX2020004901A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762585278P 2017-11-13 2017-11-13
PCT/US2018/059947 WO2019094672A1 (en) 2017-11-13 2018-11-09 A novel one-pot homogeneous process for the large scale manufacture of 2-substituted benzimidazoles

Publications (1)

Publication Number Publication Date
MX2020004901A true MX2020004901A (es) 2020-09-09

Family

ID=64572508

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020004901A MX2020004901A (es) 2017-11-13 2018-11-09 Un proceso novedoso homogeneo en un solo paso para la preparacion a gran escala de bencimidazoles sustituidos en la posicion 2.

Country Status (12)

Country Link
US (1) US11053203B2 (es)
EP (1) EP3710436A1 (es)
JP (1) JP2021502401A (es)
KR (1) KR102653426B1 (es)
CN (1) CN111372924B (es)
AU (1) AU2018366253B2 (es)
BR (1) BR112020009285A2 (es)
CA (1) CA3082375A1 (es)
MX (1) MX2020004901A (es)
SG (1) SG11202004310YA (es)
TW (1) TWI823873B (es)
WO (1) WO2019094672A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110776467A (zh) * 2019-10-30 2020-02-11 西南石油大学 一种基于苯并咪唑衍生物的缓蚀剂及其制备方法和应用
US20210301151A1 (en) * 2020-03-27 2021-09-30 Ecolab Usa Inc. Galvanized metal corrosion inhibitor compositions and methods of use
AU2022323983A1 (en) * 2021-08-02 2024-01-18 Ecolab Usa Inc. One-pot homogeneous process for the large scale manufacture of 2-substituted benzimidazoles
US20230416128A1 (en) 2022-06-23 2023-12-28 Ecolab Usa Inc. Method of Inhibiting Corrosion of a Metal in an Industrial Water System

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1176659B (de) 1960-12-27 1964-08-27 Beiersdorf & Co A G P Verfahren zur Herstellung von 1-(ª‰-Diaethyl-amino-aethyl)-2-(ª‡-hydroxy-p-methoxy-benzyl)-5-nitro-benzimidazol und seinem Hydrochlorid
US3784517A (en) * 1972-06-27 1974-01-08 Us Air Force Preparation of polybenzimidazoles in the presence of a sulfone solvent
US4001268A (en) 1974-08-07 1977-01-04 The United States Of America As Represented By The Secretary Of The Air Force Substituted phenyl-benzimidazo compounds
DE2900506A1 (de) 1979-01-08 1980-07-17 Basf Ag Verfahren zur herstellung von 2-cyanmethylbenzimidazol
SU819098A1 (ru) 1979-01-17 1981-04-07 Предприятие П/Я Р-6875 Способ получени 2-метилбензимидазола
SU1164232A1 (ru) 1983-05-11 1985-06-30 Ферганский политехнический институт Способ получени 2-ацетиламинобензимидазола
DE4305714A1 (de) 1993-02-25 1994-09-01 Hoechst Ag Verfahren zur Herstellung von substituiertem und unsubstituiertem 2-(Cyanmethyl)benzimidazol
DE19539114C1 (de) 1995-10-20 1997-04-17 Hoechst Ag Verfahren zur Aufarbeitung von Benzimidazolone enthaltenden Reaktionsgemischen
DE10201725A1 (de) 2002-01-18 2003-08-14 Boehringer Ingelheim Pharma Verfahren zur Herstellung und Reinigung von 1,7'-Dimethyl-2'-propyl-2,5'-bi-1H-benzimidazol
WO2006034418A2 (en) 2004-09-21 2006-03-30 Athersys, Inc. Benzimidazole acetic acids exhibiting crth2 receptor antagonism and uses thereof
US7470827B2 (en) * 2005-06-03 2008-12-30 Ppg Industries Ohio, Inc. Composition for the vapor phase dehydrohalogenation of 1,1,2-trihaloethane to 1,1-dihaloethylene and methods for preparing and using such composition
DE102005034279A1 (de) 2005-07-22 2007-01-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Herstellung von 1,7'-Dimethyl-2'-propyl-2,5'-bi-1H-benzimidazol
US7834130B2 (en) * 2007-02-22 2010-11-16 Pbi Performance Products, Inc. Process for the production of polybenzimidazole from a tetraminobiphenyl and an isophthalic acid
WO2009116089A2 (en) 2008-03-14 2009-09-24 Ipca Laboratories Limited Novel intermediates and method for synthesis of 4'-[(1,4'-dimethyl-2'-propyl-[2,6'- bi-1hbenzimidazol]-l-yl)methyl]-1,1-biphenyl]-2-carboxylic acid.
JP2011519840A (ja) 2008-05-02 2011-07-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １，７’−ジメチル−２’−プロピル−２，５’−ビ−１ｈ−ベンゾイミダゾールの製造
CN101891689B (zh) 2010-07-23 2012-04-18 江苏先声药物研究有限公司 盐酸γ-羟基苯达莫司汀的制备方法
WO2012028925A2 (en) 2010-09-03 2012-03-08 Ogene Systems (I) Pvt Ltd An improved process for the preparation of telmisartan
CN101979383B (zh) * 2010-09-27 2012-09-05 昆明振华制药厂有限公司 一种盐酸羟苄唑的合成方法
US20130303781A1 (en) 2010-11-24 2013-11-14 Sequent Scientific Limited Process for preparation of triclabendazole
CN102050791B (zh) 2010-12-10 2012-12-26 江苏江神药物化学有限公司 替米沙坦的关键中间体及其合成方法及由该中间体合成替米沙坦的方法
US8710082B2 (en) * 2011-02-18 2014-04-29 Board Of Trustees Of Michigan State University Benzimidazole inhibition of biofilm formation
CA2828456C (en) * 2011-03-03 2021-05-04 Zalicus Pharmaceuticals Ltd. N-benzl-amino-carboxamide inhibitors of the sodium channel
CN102250021B (zh) 2011-04-27 2013-06-05 浙江工业大学 一种喹喏西林类化合物及苯并咪唑类化合物的制备方法
CN102659686B (zh) 2012-04-11 2014-11-26 宁波九胜创新医药科技有限公司 一种2-正丙基-4-甲基-6-(1'-甲基苯并咪唑-2-基)苯并咪唑的制备方法
CN103145623A (zh) 2012-06-14 2013-06-12 史慎德 一种制备2-(((1H-苯并[d]咪唑-2-基)甲基)(1-苯甲基-1H-苯并[d]咪唑-2-基)氨基)乙酸的方法
MX365192B (es) 2012-06-19 2019-05-23 Synbias Pharma Ag Derivados de bendamustina y compuestos relacionados, y uso medico de los mismos para la terapia de cancer.
CN102827083A (zh) 2012-08-21 2012-12-19 江苏恒祥化工有限责任公司 一种2-甲基苯并咪唑的制备方法
US20140066629A1 (en) 2012-08-29 2014-03-06 E I Du Pont De Nemours And Company Process for the preparation of aromatic azole compounds
CN103435551A (zh) 2013-06-28 2013-12-11 浙江工业大学 一种2-取代的苯并咪唑类化合物的制备方法
CN103910682B (zh) 2013-11-28 2016-03-02 大连理工大学 一种基于邻苯二胺环化的苯并咪唑类化合物制备方法
EP2886536A1 (en) 2013-12-19 2015-06-24 Helmut Schickaneder Bendamustine derivatives as anti-proliferative agents
WO2016191672A1 (en) 2015-05-28 2016-12-01 Ecolab Usa Inc. 2-substituted imidazole and benzimidazole corrosion inhibitors
CN104974096B (zh) 2015-07-07 2019-02-01 威海迪素制药有限公司 一种替米沙坦中间体的制备方法
CN105198819B (zh) 2015-09-23 2017-12-15 上海泰坦科技股份有限公司 苯并咪唑‑2‑甲醛的合成工艺
TW201726664A (zh) 2015-11-26 2017-08-01 國立臺灣大學 苯并咪唑類化合物及其在心血管相關疾病之應用
US20180354909A1 (en) 2015-12-11 2018-12-13 The Board Of Regents Of The University Of Texas System Substituted benzimidazolium, pyrido-imidazolium, or pyrazino-imidazolium compounds as chemotherapeutics

Also Published As

Publication number Publication date
KR20200087779A (ko) 2020-07-21
BR112020009285A2 (pt) 2020-10-27
US20190144395A1 (en) 2019-05-16
EP3710436A1 (en) 2020-09-23
AU2018366253A1 (en) 2020-05-21
TW201922715A (zh) 2019-06-16
SG11202004310YA (en) 2020-06-29
CA3082375A1 (en) 2019-05-16
CN111372924A (zh) 2020-07-03
TWI823873B (zh) 2023-12-01
US11053203B2 (en) 2021-07-06
KR102653426B1 (ko) 2024-03-29
CN111372924B (zh) 2023-09-19
AU2018366253B2 (en) 2024-05-02
RU2020119396A (ru) 2021-12-15
WO2019094672A1 (en) 2019-05-16
JP2021502401A (ja) 2021-01-28

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