MX2020004639A - Sistemas y metodos de administracion de farmacos que comprenden acido polisialico y/u otros polimeros. - Google Patents
Sistemas y metodos de administracion de farmacos que comprenden acido polisialico y/u otros polimeros.Info
- Publication number
- MX2020004639A MX2020004639A MX2020004639A MX2020004639A MX2020004639A MX 2020004639 A MX2020004639 A MX 2020004639A MX 2020004639 A MX2020004639 A MX 2020004639A MX 2020004639 A MX2020004639 A MX 2020004639A MX 2020004639 A MX2020004639 A MX 2020004639A
- Authority
- MX
- Mexico
- Prior art keywords
- polymer
- aminoalkyl
- reacting
- polysialic acid
- peptide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6925—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a microcapsule, nanocapsule, microbubble or nanobubble
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y40/00—Manufacture or treatment of nanostructures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nanotechnology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201731277A ES2711669A1 (es) | 2017-11-02 | 2017-11-02 | Sistemas de liberacion de farmacos de acido polisialico y metodos |
| PCT/EP2018/080050 WO2019086627A1 (en) | 2017-11-02 | 2018-11-02 | Drug delivery systems and methods comprising polysialic acid and/or other polymers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2020004639A true MX2020004639A (es) | 2020-11-06 |
Family
ID=64477081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020004639A MX2020004639A (es) | 2017-11-02 | 2018-11-02 | Sistemas y metodos de administracion de farmacos que comprenden acido polisialico y/u otros polimeros. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220071917A9 (enExample) |
| EP (1) | EP3703666A1 (enExample) |
| JP (2) | JP7443230B2 (enExample) |
| AU (1) | AU2018361481B2 (enExample) |
| CA (1) | CA3079574A1 (enExample) |
| ES (1) | ES2711669A1 (enExample) |
| MX (1) | MX2020004639A (enExample) |
| WO (1) | WO2019086627A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020099513A1 (en) * | 2018-11-13 | 2020-05-22 | Lipoxen Technologies Limited | Glycopolysialylation of blinatumomab |
| AU2020266770A1 (en) | 2019-05-01 | 2021-10-14 | Universidade De Santiago De Compostela | Intracellular delivery of anti-KRAS antibodies formulated into nanocapsules |
| EP3986374B1 (en) * | 2019-06-21 | 2026-01-28 | Université catholique de Louvain | Lipid nanocapsules charged with incretin mimetics |
| WO2021163097A1 (en) | 2020-02-14 | 2021-08-19 | Chang Gung Memorial Hospital | Tandem repeat cancer-targeting peptides for molecular conjugation or engineering and uses thereof in cancer theranostics |
| CN112048002B (zh) * | 2020-08-07 | 2021-12-10 | 上海维洱生物医药科技有限公司 | 一种靶向t细胞的酶敏感纳米体系及其制备方法和应用 |
| CN112402626B (zh) * | 2020-11-26 | 2023-05-02 | 中国人民解放军陆军军医大学第二附属医院 | 一种靶向肿瘤的生物伪装纳米递药系统及其制备方法 |
| CA3221371A1 (en) * | 2021-06-08 | 2022-12-15 | Cytodigm, Inc. | Novel particle composition comprising sialic acid binding ligand |
| CN115025241B (zh) * | 2022-06-22 | 2023-08-01 | 西南民族大学 | 靶向cd22的纳米制剂及其制备方法和应用 |
| WO2024118638A2 (en) * | 2022-11-28 | 2024-06-06 | Colorado School Of Mines | Compositions and methods for making and using polymer-coated nanocapsules for targeted pharmaceutical agent delivery |
| WO2025085881A1 (en) | 2023-10-20 | 2025-04-24 | Eli Lilly And Company | Nanoparticles and formulations thereof for delivering therapeutic agents throughout the central nervous system |
| EP4652991A1 (en) | 2024-05-22 | 2025-11-26 | Universidade de Santiago de Compostela | Nanoassemblies for the intracellular delivery of active principles of aminoacidic nature |
| CN119318719B (zh) * | 2024-09-24 | 2025-09-05 | 武汉理工大学 | 一种靶向神经氨酸酶的载药纳米粒及其制备方法和应用 |
| CN119318718B (zh) * | 2024-09-24 | 2025-10-03 | 武汉理工大学 | 一种pH/神经氨酸酶双响应载药纳米粒及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2294535T3 (es) * | 2003-08-12 | 2008-04-01 | Lipoxen Technologies Limited | Derivados del acido polisialico. |
| EP2106806A1 (en) | 2008-03-31 | 2009-10-07 | Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. | Nanoparticles for targeted delivery of active agents to the lung |
| ES2385995B2 (es) | 2011-01-10 | 2013-05-21 | Universidade De Santiago De Compostela | Nanocápsulas con cubierta polimérica |
| CA2825016C (en) | 2011-01-24 | 2021-02-16 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Nanoparticles for dermal and systemic delivery of drugs |
| BR112014006596A2 (pt) | 2011-09-21 | 2017-03-28 | Yissum Res Dev Co | nanopartícula que encapsula uma pluralidade de nanocarreadores, composição, uso de uma nanopartícula, kit, sistema de entrega, processo para obter uma nanopartícula, e, processo de nanoaspersão para obter as nanopartículas |
| JP2015509085A (ja) * | 2012-01-01 | 2015-03-26 | キュービーアイ エンタープライゼズ リミテッドQbi Enterprises Ltd. | 治療剤および診断剤の選択的送達のためのendo180を標的とする粒子 |
| US9993439B2 (en) * | 2012-06-20 | 2018-06-12 | University Of Waterloo | Mucoadhesive nanoparticle delivery system |
| PL229276B1 (pl) | 2015-07-17 | 2018-06-29 | Univ Jagiellonski | Nanokapsuła do przenoszenia związku lipofilowego i sposób jej wytwarzania |
-
2017
- 2017-11-02 ES ES201731277A patent/ES2711669A1/es not_active Withdrawn
-
2018
- 2018-11-02 EP EP18808228.3A patent/EP3703666A1/en active Pending
- 2018-11-02 MX MX2020004639A patent/MX2020004639A/es unknown
- 2018-11-02 JP JP2020524446A patent/JP7443230B2/ja active Active
- 2018-11-02 AU AU2018361481A patent/AU2018361481B2/en active Active
- 2018-11-02 WO PCT/EP2018/080050 patent/WO2019086627A1/en not_active Ceased
- 2018-11-02 US US16/760,527 patent/US20220071917A9/en active Pending
- 2018-11-02 CA CA3079574A patent/CA3079574A1/en active Pending
-
2024
- 2024-02-21 JP JP2024024604A patent/JP7756185B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20210228494A1 (en) | 2021-07-29 |
| EP3703666A1 (en) | 2020-09-09 |
| AU2018361481B2 (en) | 2024-06-13 |
| JP2024059777A (ja) | 2024-05-01 |
| WO2019086627A1 (en) | 2019-05-09 |
| JP7443230B2 (ja) | 2024-03-05 |
| CA3079574A1 (en) | 2019-05-29 |
| ES2711669A1 (es) | 2019-05-06 |
| US20220071917A9 (en) | 2022-03-10 |
| JP2021516211A (ja) | 2021-07-01 |
| JP7756185B2 (ja) | 2025-10-17 |
| AU2018361481A1 (en) | 2020-05-07 |
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