MX2020004158A - Polisacaridos pecticos enzimaticamente hidrolizados para tratar o prevenir infecciones. - Google Patents

Polisacaridos pecticos enzimaticamente hidrolizados para tratar o prevenir infecciones.

Info

Publication number
MX2020004158A
MX2020004158A MX2020004158A MX2020004158A MX2020004158A MX 2020004158 A MX2020004158 A MX 2020004158A MX 2020004158 A MX2020004158 A MX 2020004158A MX 2020004158 A MX2020004158 A MX 2020004158A MX 2020004158 A MX2020004158 A MX 2020004158A
Authority
MX
Mexico
Prior art keywords
residues
polysaccharides
carrot
product
rhamnose
Prior art date
Application number
MX2020004158A
Other languages
English (en)
Inventor
Ruud Albers
Maria Tzoumaki
Original Assignee
Nutrileads B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2018/074127 external-priority patent/WO2020048609A1/en
Application filed by Nutrileads B V filed Critical Nutrileads B V
Publication of MX2020004158A publication Critical patent/MX2020004158A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/732—Pectin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/231—Pectin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01015—Polygalacturonase (3.2.1.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01067—Galacturan 1,4-alpha-galacturonidase (3.2.1.67)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01082—Exo-poly-alpha-galacturonosidase (3.2.1.82)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/02—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2) hydrolysing N-glycosyl compounds (3.2.2)
    • C12Y302/02002—Inosine nucleosidase (3.2.2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/02—Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/0201—Pectin lyase (4.2.2.10)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/324—Foods, ingredients or supplements having a functional effect on health having an effect on the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01011—Pectinesterase (3.1.1.11)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dispersion Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La invención se refiere a un producto para uso en el tratamiento terapéutico o profiláctico de infecciones, dicho tratamiento comprende la administración oral del producto, en el que el producto se selecciona de una 5 formulación nutricional, un producto alimenticio, un suplemento dietético, una bebida y un producto farmacéutico, dicho producto contiene polisacáridos de zanahoria RG-I que tienen las siguientes características de combinación: un peso molecular en el intervalo de 10-300 kDa;• una estructura que consiste en residuos de ácido galacturónico y residuos de ramnosa, dichos residuos de ramnosa están contenidos en residuos de alfa(1 ? 4)-galacturónico-alfa(1 ? 2)-ramnosa; la siguiente composición de monosacáridos: 20-60 % en moles de residuos de ácido galacturónico, en la que los ácidos galacturónicos individuales pueden metilarse y/o acetil-esterificarse;? 8-50 % en moles de residuos de ramnosa;? 0-40 % en moles de residuos de arabinosa; ? 0-40 % en moles de residuos de galactosa; ? relación molar de residuos de ácido galacturónico a residuos de ramnosa en el intervalo de 5:1 a 1:1; los residuos de ácido galacturónico, los residuos de ramnosa, los residuos de arabinosa y los residuos de galactosa juntos constituyen al menos el 85 % en moles de los residuos de monosacáridos en los polisacáridos RG-I de zanahoria. Estos polisacáridos RG-I de zanahoria se pueden producir hidrolizando parcialmente los polisacáridos pécticos presentes en un aislado de pectina de zanahoria. La eficacia de los polisacáridos RG-I de zanahoria contra las infecciones mejora sustancialmente hidrolizando enzimáticamente los polisacáridos RG-I para eliminar al menos parte del componente de homogalacturonano.
MX2020004158A 2017-10-23 2018-10-23 Polisacaridos pecticos enzimaticamente hidrolizados para tratar o prevenir infecciones. MX2020004158A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17197706 2017-10-23
PCT/EP2018/074127 WO2020048609A1 (en) 2018-09-07 2018-09-07 Prebiotic for treating disorders associated with disturbed composition or functionality of the intestinal microbiome
PCT/EP2018/079055 WO2019081523A1 (en) 2017-10-23 2018-10-23 ENZYMATIC HYDROLYZED PECTIC POLYSACCHARIDES FOR THE TREATMENT OR PREVENTION OF INFECTIONS

Publications (1)

Publication Number Publication Date
MX2020004158A true MX2020004158A (es) 2020-10-07

Family

ID=63896203

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020004158A MX2020004158A (es) 2017-10-23 2018-10-23 Polisacaridos pecticos enzimaticamente hidrolizados para tratar o prevenir infecciones.

Country Status (10)

Country Link
US (1) US11723915B2 (es)
EP (1) EP3700357B1 (es)
JP (1) JP7234247B2 (es)
KR (1) KR20200078570A (es)
CN (1) CN111683546A (es)
AU (1) AU2018356377B2 (es)
CA (1) CA3079933A1 (es)
MX (1) MX2020004158A (es)
PL (1) PL3700357T3 (es)
WO (1) WO2019081523A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110511298A (zh) * 2019-09-09 2019-11-29 浙江大学 一种提取富含半乳糖侧链的rg-i果胶多糖的方法
EP3895710A1 (en) * 2020-04-15 2021-10-20 DSM IP Assets B.V. Food and/or feed compositions to manage immune homeostasis
CN115251364B (zh) * 2022-07-25 2023-09-19 福州大学 一种改性茶果胶的制备方法及其制品和应用
WO2024074377A1 (en) 2022-10-03 2024-04-11 Nutrileads B.V. Rhamnogalacturoran i for use in the treatment of dyspnea or persistent cough caused or exacerbated by viral respiratory infection in patients suffering from asthma, copd or post-viral lung complaints
WO2024105131A1 (en) * 2022-11-15 2024-05-23 Nutrileads B.V. Prebiotic composition for stabilizing a healthy gut microbiota
CN117512032B (zh) * 2023-11-07 2024-04-30 北京市农林科学院 低分子量hg型果胶的制备方法及其构象表征

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6492350B2 (en) 2000-01-27 2002-12-10 Jdc (Hawaii) Inc. Chitin oligosaccharides and/or chitosan oligosaccharides for preventing or treating common cold or treating pain
DE10019076A1 (de) * 2000-04-06 2001-10-18 Lang Christine Verwendung von Polygalakturoniden als Lebensmittelzusatzstoffe
DE10057976B4 (de) * 2000-11-22 2005-02-03 Südzucker AG Mannheim/Ochsenfurt Verfahren zur Herstellung von Pektinhydrolyseprodukten
WO2004084652A1 (en) * 2003-03-26 2004-10-07 Novozymes A/S Method of producing vegetable puree
EP1765874A1 (en) 2004-03-26 2007-03-28 Glycogenesys, Inc. Modified pectins, compositions and methods related thereto
US8603461B2 (en) 2005-04-26 2013-12-10 TEAGASC—The Agriculture and Food Development Authority Probiotic composition suitable for animals
WO2009042230A1 (en) 2007-09-27 2009-04-02 Biopolymer Engineering, Inc. Dba Biothera, Inc ß-GLUCAN TREATMENT OF UPPER RESPIRATORY TRACT INFECTION SYMPTOMS AND PSYCHOLOGICAL WELL-BEING
CN102762597A (zh) * 2009-12-11 2012-10-31 联合利华公众股份有限公司 适合调节免疫应答的多糖
WO2011136634A1 (en) 2010-04-26 2011-11-03 N.V. Nutricia Preventing salmonella infection induced weight loss
JP5996837B2 (ja) 2010-05-28 2016-09-21 小林製薬株式会社 インフルエンザウイルスの感染抑制剤
US9951148B2 (en) 2011-04-29 2018-04-24 Nutrileads B.V. Method for isolation of polysaccharides
CN102277398B (zh) * 2011-07-18 2013-10-16 新乡医学院 高生物利用度改性果胶制备工艺及抗肿瘤应用
CN102784193A (zh) 2012-08-16 2012-11-21 魏舒畅 采用耦合技术制备红芪提取物的方法
WO2014150139A1 (en) 2013-03-15 2014-09-25 Microbiome Therapeutics, Llc. Activated soy pod fiber
US9393259B2 (en) 2013-03-21 2016-07-19 Lonza Ltd. Composition comprising arabinogalactan and polyphenols from larch trees
JP6233032B2 (ja) 2013-06-05 2017-11-22 デクセリアルズ株式会社 光学活性化合物の製造方法
CN103980371B (zh) * 2014-04-22 2016-06-08 中国农业科学院北京畜牧兽医研究所 苜蓿多糖的制备方法及用途
WO2015192247A1 (en) 2014-06-21 2015-12-23 The Royal Institution For The Advancement Of Learning/Mcgill University Enzymatic production of prebiotic oligosaccharides from potato pulp
GB201502668D0 (en) * 2015-02-17 2015-04-01 Glycomar Ltd And Albert Bartlett & Sons Airdrie Ltd Method for isolation of polysaccharides
KR101774566B1 (ko) 2015-11-05 2017-09-04 한국식품연구원 면역기능 증진 활성이 우수한 효소처리 보리잎 유래 다당 분획물 및 이의 용도

Also Published As

Publication number Publication date
AU2018356377A1 (en) 2020-05-07
CA3079933A1 (en) 2019-05-02
CN111683546A (zh) 2020-09-18
KR20200078570A (ko) 2020-07-01
EP3700357B1 (en) 2024-04-03
US20200246373A1 (en) 2020-08-06
US11723915B2 (en) 2023-08-15
PL3700357T3 (pl) 2024-07-29
JP2021500085A (ja) 2021-01-07
AU2018356377B2 (en) 2024-08-08
BR112020008079A2 (pt) 2020-11-03
EP3700357A1 (en) 2020-09-02
EP3700357C0 (en) 2024-04-03
WO2019081523A1 (en) 2019-05-02
JP7234247B2 (ja) 2023-03-07

Similar Documents

Publication Publication Date Title
MX2020004158A (es) Polisacaridos pecticos enzimaticamente hidrolizados para tratar o prevenir infecciones.
HRP20191440T1 (hr) Sastavi koji sadrže bakterijske sojeve
BRPI0910112A8 (pt) Preparação de oligossacarídeo de (arabino)xilano
WO2009092383A3 (en) Products and methods to prevent infection
EP2014181A3 (en) Compositions based on prebiotic and immunogenic ingredients for the prevention and treatment of gastroenteric disorders caused by dysbiosis and/or alterations of the normal intestinal flora
BR112012005768A2 (pt) agente antiobesidade, bebida ou alimento antiobesidade, agente de melhoramento de tolerância à glicose, e alimento ou bebida para o melhoramento de tolerância à glicose
MX2021002478A (es) Prebiotico para el tratamiento de trastornos asociados a la composicion o funcionalidad alterada del microbioma intestinal.
WO2017022962A8 (ko) Ripk 억제제를 유효성분으로 포함하는 면역질환의 예방 또는 치료용 조성물
WO2011106417A3 (en) Garcinia mangostana l. and iridoid based formulations
MX2019009711A (es) Mejoras en o con respecto a compuestos organicos.
MX2016014050A (es) Combinacion de un acido hialuronico y un polisacarido sulfatado.
BR112018068642A2 (pt) composição e uso de composição
NZ720863A (en) Anti-viral properties of aloe vera and acquired immune deficiency syndrome (aids) treatment
WO2020245809A3 (en) Identification and selection of a plant starting material of a plant chondroitin sulfate and hyaluronic acid, and transformation of such plant starting material to obtain ingredients for use in foods, supplements, medical devices or drugs
HRP20231090T1 (hr) Pripravci i metode sinergističkog tretmana glikokaliksa
WO2005076761A3 (en) Composition for preenting a cold
TR201713929A2 (tr) Ki̇tosan ve alji̇natin hemostati̇k kompozi̇syonlari
MX2017004760A (es) Formulacion esterilizada por calor que comprende quitosan y proceso para preparacion de la misma.
Abd El-Mawla et al. HPLC analysis and role of the Saudi Arabian propolis in improving the pathological changes of kidney treated with monosodium glutamate
AR079375A1 (es) Soluciones de rehidratacion oral que comprenden dextrosa. metodo de preparacion.
BR112012030485A2 (pt) composição para prevenção ou tratamento de osteoporose e processo de fabricação para a mesma
CL2011000183A1 (es) Uso de una composicion de extracto seco de buddleja globosa, para preparar un fitofarmaco, medicamento o un nutraceutico para prevenir o tratar trastornos gastrointestinales causados por tratamientos antimicrobianos.
WO2016195194A3 (ko) 신규한 tlr2 길항제
BR112018013804A2 (pt) entrega baseada em alimentos de agentes terapêuticos para tratamento de encefalopatia hepática
MX2021001145A (es) Formulación de liberación inmediata de una combinación triple de principios activos farmacéuticos, útil en el tratamiento del síndrome del ovario poliquístico.