MX2021001145A - Formulación de liberación inmediata de una combinación triple de principios activos farmacéuticos, útil en el tratamiento del síndrome del ovario poliquístico. - Google Patents
Formulación de liberación inmediata de una combinación triple de principios activos farmacéuticos, útil en el tratamiento del síndrome del ovario poliquístico.Info
- Publication number
- MX2021001145A MX2021001145A MX2021001145A MX2021001145A MX2021001145A MX 2021001145 A MX2021001145 A MX 2021001145A MX 2021001145 A MX2021001145 A MX 2021001145A MX 2021001145 A MX2021001145 A MX 2021001145A MX 2021001145 A MX2021001145 A MX 2021001145A
- Authority
- MX
- Mexico
- Prior art keywords
- active pharmaceutical
- pharmaceutical ingredients
- immediate release
- release formulation
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
La invención se refiere a una formulación de liberación inmediata para administración oral, que comprende; a) una combinación de tres principios activos farmacéuticos que son espironolactona; pioglitazona o una sal de la misma; y metformina o una sal de la misma; y b) polietilenglicol sólido que tiene un peso molecular promedio de 3350 a 8000 g/mol; en la que: cada uno de los principios activos farmacéuticos está presente en una cantidad terapéuticamente efectiva; y el polietilenglicol está presente en una cantidad tal que disminuye los perfiles de disolución in vitro de cada uno de los principios activos farmacéuticos sin modificar el tiempo de disgregación de la formulación en comparación con los perfiles de disolución de cada uno de los principios activos farmacéuticos de una formulación que tiene la misma composición pero sin el polietilenglicol sólido, así como, a su procedimiento de preparación.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18382586 | 2018-08-02 | ||
PCT/EP2019/070751 WO2020025742A1 (en) | 2018-08-02 | 2019-08-01 | Immediate release formulation of a triple combination of active pharmaceutical ingredients useful in the treatment of polycystic ovary syndrome |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021001145A true MX2021001145A (es) | 2021-06-23 |
Family
ID=63244530
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021001145A MX2021001145A (es) | 2018-08-02 | 2019-08-01 | Formulación de liberación inmediata de una combinación triple de principios activos farmacéuticos, útil en el tratamiento del síndrome del ovario poliquístico. |
Country Status (7)
Country | Link |
---|---|
US (1) | US20210290639A1 (es) |
EP (1) | EP3829546A1 (es) |
JP (1) | JP2021533109A (es) |
KR (1) | KR20210045404A (es) |
CA (1) | CA3107945A1 (es) |
MX (1) | MX2021001145A (es) |
WO (1) | WO2020025742A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201518979D0 (en) * | 2015-10-27 | 2015-12-09 | Univ Leuven Kath | Treatment of hepatic steatosis related oligo-ovulation |
CN114796239A (zh) * | 2022-05-13 | 2022-07-29 | 上海金不换兰考制药有限公司 | 一种螺内酯组合物、制剂及制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9060941B2 (en) * | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US20070286903A1 (en) * | 2006-06-13 | 2007-12-13 | Becicka Brian T | Composition and method for taste masking |
NZ602809A (en) * | 2010-05-05 | 2015-02-27 | Boehringer Ingelheim Int | Pharmaceutical formulations comprising pioglitazone and linagliptin |
WO2016059219A1 (en) * | 2014-10-17 | 2016-04-21 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
EP3025707A1 (en) * | 2014-11-27 | 2016-06-01 | Arven Ilac Sanayi Ve Ticaret A.S. | A multilayer tablet comprising metformin and pioglitazone |
GB201518979D0 (en) * | 2015-10-27 | 2015-12-09 | Univ Leuven Kath | Treatment of hepatic steatosis related oligo-ovulation |
-
2019
- 2019-08-01 CA CA3107945A patent/CA3107945A1/en active Pending
- 2019-08-01 WO PCT/EP2019/070751 patent/WO2020025742A1/en unknown
- 2019-08-01 EP EP19745170.1A patent/EP3829546A1/en not_active Withdrawn
- 2019-08-01 US US17/265,198 patent/US20210290639A1/en not_active Abandoned
- 2019-08-01 JP JP2021504798A patent/JP2021533109A/ja active Pending
- 2019-08-01 MX MX2021001145A patent/MX2021001145A/es unknown
- 2019-08-01 KR KR1020217004802A patent/KR20210045404A/ko unknown
Also Published As
Publication number | Publication date |
---|---|
WO2020025742A1 (en) | 2020-02-06 |
EP3829546A1 (en) | 2021-06-09 |
WO2020025742A9 (en) | 2020-10-08 |
US20210290639A1 (en) | 2021-09-23 |
CA3107945A1 (en) | 2020-02-06 |
KR20210045404A (ko) | 2021-04-26 |
JP2021533109A (ja) | 2021-12-02 |
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